VASOGRAIN TABLET 20'S

How VASOGRAIN TABLET 20'S Works

• VASOGRAIN TABLET 20'S is a combination medicine meticulously formulated to alleviate the debilitating symptoms of migraine headaches. It synergistically combines the therapeutic actions of ergotamine, caffeine, and paracetamol to provide comprehensive relief. Let's delve into the mechanism of each component:
• **Ergotamine Tartrate:** Ergotamine, a vasoconstrictor, is the cornerstone of VASOGRAIN's action. During a migraine, blood vessels in the brain dilate, contributing to the throbbing pain. Ergotamine works by constricting these widened blood vessels, returning them to their normal size. This constriction reduces the excessive blood flow and pressure within the cranial vessels, thereby diminishing the headache.
• **Caffeine:** Caffeine plays a dual role in VASOGRAIN. Firstly, it enhances the vasoconstrictive effect of ergotamine. Caffeine itself possesses mild vasoconstrictive properties, and by working in conjunction with ergotamine, it amplifies the overall constriction of blood vessels. Secondly, caffeine acts as an analgesic adjuvant. It reduces fatigue and enhances alertness. It can potentiate the pain-relieving effects of paracetamol, leading to a more effective reduction in migraine pain.
• **Paracetamol:** Paracetamol, a widely used analgesic and antipyretic, provides pain relief by inhibiting the production of prostaglandins in the brain. Prostaglandins are substances that contribute to inflammation and pain signaling. By reducing prostaglandin synthesis, paracetamol helps to alleviate the pain associated with migraines. While paracetamol primarily addresses pain, it also contributes to reducing any associated fever that might accompany a migraine attack.
• In essence, VASOGRAIN TABLET 20'S tackles migraines through a multi-pronged approach: Ergotamine directly constricts dilated blood vessels, caffeine enhances ergotamine's effect and provides additional pain relief, and paracetamol reduces pain and fever. This synergistic combination offers a comprehensive solution for migraine sufferers.

Like all medicines, Vasograin Tablet can cause side effects, although not everybody gets them. **Common Side Effects (may affect up to 1 in 10 people):** * Drowsiness * Dizziness * Nausea * Dry mouth * Muscle weakness **Uncommon Side Effects (may affect up to 1 in 100 people):** * Blurred vision * Difficulty concentrating * Insomnia * Restlessness * Increased heart rate * Low blood pressure * Allergic reactions (skin rash, itching, hives) **Rare Side Effects (may affect up to 1 in 1,000 people):** * Severe allergic reaction (anaphylaxis) with symptoms like swelling of the face, lips, tongue, or throat, difficulty breathing, and loss of consciousness (seek immediate medical attention). * Seizures * Confusion * Hallucinations * Liver problems (yellowing of the skin or eyes, dark urine, pale stools) * Changes in blood cell counts **Very Rare Side Effects (may affect up to 1 in 10,000 people):** * Heart attack * Stroke * Neuroleptic Malignant Syndrome (a severe reaction with high fever, muscle rigidity, altered mental status, and autonomic dysfunction). **Frequency Not Known (cannot be estimated from the available data):** * Rebound headaches (headaches that occur more frequently or severely when the medication is stopped). * Medication-overuse headache (chronic daily headache caused by regular overuse of pain relievers). This is not an exhaustive list of side effects. If you experience any troublesome or persistent side effects, stop taking Vasograin Tablet and consult your doctor or pharmacist.

• If you miss a dose of Vasograin Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep VASOGRAIN TAB 1X20 away from the reach of children and pets.
• Store VASOGRAIN TAB 1X20 at room temperature.

• **Take Vasograin at the First Sign of a Migraine:** For best results, take Vasograin tablet as soon as you feel a migraine coming on. Early intervention can help reduce the severity and duration of the headache.
• **Stay Hydrated:** Drink plenty of water when taking Vasograin. Dehydration can worsen headaches, so staying hydrated can complement the effects of the medication. Aim for at least 8 glasses of water a day, especially during a migraine episode.
• **Avoid Common Migraine Triggers:** Identify and avoid your personal migraine triggers. Common triggers include certain foods (e.g., aged cheese, chocolate, caffeine), stress, lack of sleep, and changes in weather. Keeping a migraine diary can help you pinpoint your triggers.
• **Create a Calm Environment:** When a migraine strikes, find a quiet, dark room to lie down in. Reduce sensory stimulation by turning off lights and minimizing noise. Applying a cold compress to your forehead or temples can also provide relief and enhance the effects of Vasograin.
• **Follow Your Doctor's Instructions:** Always take Vasograin tablet exactly as prescribed by your doctor. Do not exceed the recommended dose or frequency. If your migraines do not improve or worsen, consult your doctor for further evaluation and alternative treatment options.

• VASOGRAIN TABLET 20'S is generally taken without regard to food. However, if you experience stomach upset, it is advisable to take it with food or milk.
• Avoid excessive caffeine intake (e.g., coffee, tea, chocolate) as it may interfere with the medication's effects or worsen side effects.