VICRYL 2 NW 2317

How VICRYL 2 NW 2317 Works

• VICRYL 2 NW 2317 is a synthetic absorbable suture composed of Polyglactin 910, a copolymer made from 90% glycolide and 10% L-lactide. This unique composition allows VICRYL sutures to offer predictable and reliable absorption while providing excellent tensile strength during the critical wound healing period. The suture is coated with a mixture of calcium stearate and Polyglactin 370 (a copolymer of glycolide and lactide), which reduces tissue drag and improves handling properties, facilitating smooth passage through tissue with minimal trauma.
• The mechanism of action of VICRYL 2 NW 2317 involves a process called hydrolysis. Once implanted, moisture from the body gradually penetrates the suture filaments. This moisture breaks down the polymer chains of Polyglactin 910 into glycolic and lactic acids, which are then metabolized and eliminated by the body. The absorption process begins around 14 days post-implantation, with significant tensile strength remaining during the initial stages of wound healing. At 2 weeks, approximately 75% of the original tensile strength remains, decreasing to around 50% at 3 weeks, and 25% at 4 weeks. The suture is essentially absorbed within 56 to 70 days.
• The braided structure of VICRYL 2 NW 2317 provides excellent knot security, ensuring that the suture holds its position within the tissue. This is crucial for maintaining wound closure and preventing dehiscence (wound separation). The coating further enhances knot security by reducing slippage and friction during knot tying. The predictable absorption profile minimizes the risk of long-term foreign body reaction, promoting better tissue compatibility and reducing the incidence of inflammation or irritation at the suture site.
• In essence, VICRYL 2 NW 2317 works by providing initial wound support through its high tensile strength and secure knotting properties. As the wound heals, the suture gradually loses strength and is absorbed, eliminating the need for suture removal and minimizing patient discomfort. The hydrolytic degradation ensures that the breakdown products are biocompatible and easily eliminated, contributing to optimal wound healing outcomes. The suture's design minimizes tissue trauma and promotes a faster, more comfortable recovery for the patient. This suture is particularly suitable for soft tissue approximation and ligation, where a combination of strength and absorbability is desired.
• The Polyglactin 910 material is biologically inert and elicits only a minimal tissue reaction during absorption. The suture's multifilament construction provides good handling and knot tying properties, making it easy for surgeons to use in a variety of surgical procedures. The violet color (or undyed version) provides good visibility in the surgical field. VICRYL sutures are commonly used in general surgery, plastic surgery, obstetrics/gynecology, ophthalmology, and other specialties where absorbable sutures are indicated. Its reliable performance and predictable absorption make it a trusted choice for surgeons worldwide.

As with all surgical procedures, the use of VICRYL sutures is associated with potential risks. Side effects may include: * **Wound Dehiscence:** Separation of wound edges. * **Infection:** Bacterial contamination at the surgical site, potentially leading to serious complications. * **Inflammatory Reaction:** Characterized by redness, swelling, and pain around the suture site. * **Pain:** Discomfort at the suture site, which can range from mild to severe. * **Irritation:** Localized reaction to the suture material. * **Bleeding:** Hemorrhage from the wound. * **Sinus Formation:** Development of an abnormal channel from a deeper site to the skin surface. * **Suture Extrusion:** Expulsion of the suture material from the wound. * **Delayed Absorption:** Prolonged degradation of the suture material, potentially leading to persistent inflammation or other complications. * **Tissue Reaction:** Body's response to the suture material, which could manifest as a foreign body reaction. * **Allergic reaction:** Allergic reactions to the suture material can occur, although rare. Symptoms may include itching, rash, swelling, or difficulty breathing. Seek immediate medical attention if you experience signs of an allergic reaction. This is not an exhaustive list. Consult with your surgeon or healthcare provider for comprehensive information regarding the risks and side effects associated with VICRYL sutures.

• Since VICRYL 2 NW 2317 is typically administered by a healthcare professional in a clinical setting, missing a dose is unlikely. VICRYL 2 NW 2317 is not intended for self-administration, so the concept of a 'missed dose' does not generally apply. Follow the instructions of your doctor or healthcare provider.

• Keep VICRYL 2 NW 2317 away from the reach of children and pets.
• Store VICRYL 2 NW 2317 at room temperature.

• **Proper Handling is Key:** Always handle VICRYL 2 NW 2317 sutures with care. Avoid crushing or damaging the suture material with surgical instruments. Damaged sutures can compromise tensile strength and increase the risk of breakage during suturing. Use appropriate needle holders and grasping techniques to ensure the suture remains intact and performs as intended. Employ gentle handling to minimize tissue trauma and optimize wound healing outcomes.
• **Suture Size Selection Matters:** Choosing the correct suture size for the specific tissue type and wound closure requirements is crucial. VICRYL 2 NW 2317, being a size 2 suture, is suitable for certain applications. Consider tissue thickness, tension, and the desired level of support when selecting suture size. Using a suture that is too large can lead to excessive tissue trauma, while a suture that is too small may not provide adequate wound closure strength. Consult surgical guidelines and consider individual patient factors to determine the appropriate suture size for each case.
• **Knot Security is Paramount:** Securing knots properly is essential for preventing wound dehiscence and ensuring long-term wound closure integrity. Use established surgical knot tying techniques and ensure that knots are tied securely and without excessive tension. Avoid creating excessively tight knots, as this can lead to tissue strangulation and ischemia. Employ the appropriate number of throws for each knot and consider using knot-tying instruments to enhance precision and security. Regularly inspect knots during and after suturing to confirm their stability and integrity.
• **Wound Tension Management is Vital:** Managing wound tension effectively is critical for achieving optimal wound healing outcomes. Excessive tension on the wound edges can impair blood supply, increase the risk of infection, and lead to delayed healing or dehiscence. Employ techniques such as undermining, layered closure, or the use of tension-relieving sutures to minimize tension on the primary wound closure. Consider using adjuncts such as surgical tapes or wound dressings to provide additional support and reduce tension on the wound edges. Proper wound tension management promotes optimal tissue approximation, reduces scarring, and enhances overall cosmetic results.
• **Storage Conditions Influence Performance:** Proper storage of VICRYL 2 NW 2317 sutures is essential for maintaining their integrity and performance characteristics. Store sutures in a cool, dry place away from direct sunlight and extreme temperatures. Avoid exposing sutures to moisture or corrosive substances, as this can compromise their strength and pliability. Check the expiration date of the sutures before use and discard any expired or damaged sutures. Adhering to proper storage conditions ensures that sutures retain their optimal properties and perform as intended during surgical procedures.

• VICRYL 2 NW 2317 does not typically interact with food. You can maintain your regular diet while using this medication. However, if you have specific dietary restrictions or concerns due to your medical condition, consult your doctor or healthcare provider for personalized advice.