VOGLI TRIO 0.3MG TABLET 10'S
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VOGLI TRIO 0.3MG TABLET 10'SVOGLI TRIO 0.3MG TABLET 10'SVOGLI TRIO 0.3MG TABLET 10'S
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VOGLI TRIO 0.3MG TABLET 10'S

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VOGLI TRIO 0.3MG TABLET 10'S

By MEDLEY PHARMACEUTICALS LTD

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192.19

₹163.36

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Product DetailsArrow

Content Reviewed By:

Dr. Rajesh Sharma

, (MBBS)

Written By:

Ms. Priyanka Shah

, (B.Pharm)

About VOGLI TRIO 0.3MG TABLET 10'S

  • VOGLI TRIO 0.3MG TABLET 10'S is a combination medicine specifically designed to help manage blood sugar levels in adults with type 2 diabetes mellitus. It combines three powerful active ingredients to provide comprehensive glycemic control: Voglibose, Metformin, and Glimepiride.
  • Voglibose, an alpha-glucosidase inhibitor, works by slowing down the absorption of carbohydrates from the small intestine. This action helps to prevent sharp spikes in blood sugar levels after meals, effectively managing postprandial hyperglycemia. By inhibiting the enzymes that break down complex carbohydrates into glucose, Voglibose ensures a more gradual release of glucose into the bloodstream.
  • Metformin, a biguanide, is a cornerstone in the treatment of type 2 diabetes. It primarily works by decreasing glucose production in the liver and improving the body's sensitivity to insulin. Metformin also helps to reduce the amount of sugar absorbed from food and can improve cholesterol levels, offering additional cardiovascular benefits. It is known for its effectiveness in lowering fasting blood sugar levels.
  • Glimepiride, a sulfonylurea, stimulates the pancreas to release more insulin. Insulin is crucial for allowing glucose to enter cells, where it can be used for energy. By increasing insulin secretion, Glimepiride helps to lower blood sugar levels throughout the day. The combination of these three drugs targets different mechanisms in the body to lower blood sugar.
  • This combination allows for a synergistic effect, providing better blood sugar control than any of the drugs used alone. VOGLI TRIO 0.3MG TABLET 10'S is usually prescribed when diet, exercise, and single-agent therapy are not sufficient to achieve adequate glycemic control. It is important to use this medicine as directed by your healthcare provider, along with following a healthy diet and regular exercise program, to achieve the best results in managing your diabetes.

Uses of VOGLI TRIO 0.3MG TABLET 10'S

  • Treatment of type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Improving insulin sensitivity
  • Controlling blood sugar levels after meals
  • Managing insulin resistance in Polycystic Ovary Syndrome (PCOS) (off-label use)
  • Reducing the risk of heart disease (indirectly through blood sugar control)

How VOGLI TRIO 0.3MG TABLET 10'S Works

  • VOGLI TRIO 0.3MG TABLET 10'S is a combination medication designed to manage blood sugar levels in individuals with type 2 diabetes. It combines three active ingredients: Voglibose, Metformin, and a Sulfonylurea (typically Glimepiride or Gliclazide, depending on the specific formulation). Each component works through a different mechanism to achieve comprehensive glycemic control.
  • Voglibose is an alpha-glucosidase inhibitor. It functions by delaying the absorption of glucose from the small intestine into the bloodstream. After a meal, carbohydrates are broken down into glucose, which is then absorbed. Voglibose inhibits the enzymes (alpha-glucosidases) responsible for breaking down complex carbohydrates into simpler sugars. By slowing down this process, Voglibose reduces the rapid rise in blood glucose levels that typically occurs after eating, thus helping to control postprandial (after-meal) hyperglycemia.
  • Metformin is a biguanide that primarily works by decreasing glucose production in the liver. It also enhances insulin sensitivity in muscle tissue, allowing cells to utilize glucose more effectively. Additionally, Metformin reduces glucose absorption from the intestines. It does not stimulate insulin release, so it carries a lower risk of hypoglycemia (low blood sugar) compared to sulfonylureas. Metformin is considered a first-line treatment for type 2 diabetes due to its efficacy and safety profile.
  • The Sulfonylurea component (Glimepiride or Gliclazide) stimulates the pancreas to release more insulin. Insulin is a hormone that helps glucose enter cells from the bloodstream, thereby lowering blood sugar levels. Sulfonylureas bind to specific receptors on pancreatic beta cells, leading to increased insulin secretion. This helps to reduce both fasting and postprandial blood glucose levels. However, because sulfonylureas increase insulin secretion, there is a risk of hypoglycemia, particularly if meals are skipped or delayed.
  • In combination, these three drugs provide a multi-faceted approach to managing blood sugar. Voglibose addresses postprandial hyperglycemia by slowing down glucose absorption. Metformin reduces hepatic glucose production and improves insulin sensitivity. The Sulfonylurea increases insulin secretion from the pancreas. This synergistic effect helps to achieve better glycemic control than any single drug could provide alone. Patients taking VOGLI TRIO 0.3MG TABLET 10'S should adhere to their prescribed diet and exercise regimen for optimal results. Regular monitoring of blood glucose levels is also essential to ensure that the medication is effectively managing their diabetes and to adjust the dosage if necessary.
  • It's important to note that while VOGLI TRIO 0.3MG TABLET 10'S is effective in managing blood sugar, it is not a cure for diabetes. Consistent lifestyle modifications, including a healthy diet, regular physical activity, and weight management, are crucial for long-term diabetes management. Patients should also be aware of potential side effects associated with each component of the medication. Common side effects include gastrointestinal issues like nausea, diarrhea, and abdominal discomfort. Hypoglycemia is a risk, particularly with the Sulfonylurea component. Patients should consult their healthcare provider if they experience any concerning symptoms or have questions about their medication.

Side Effects of VOGLI TRIO 0.3MG TABLET 10'SArrow

The most common side effects of VOGLI TRIO 0.3MG TABLET 10'S are hypoglycemia (low blood glucose level), nausea, diarrhea, abdominal pain, flatulence, constipation, vomiting, and altered taste. Some patients may experience serious side effects like lactic acidosis (symptoms include deep and rapid breathing, nausea, vomiting, stomach pain), allergic reaction (rash, itching, swelling), liver problems (dark urine, yellowing of skin/eyes), and blood disorders. Other possible side effects include blurred vision, headache, dizziness, weakness, metallic taste, and increased sweating. Consult your doctor immediately if you experience any severe or persistent side effects.

Safety Advice for VOGLI TRIO 0.3MG TABLET 10'SArrow

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Allergies

Allergies

Do not use VOGLI TRIO 0.3MG TABLET 10'S if you are allergic to it.

Dosage of VOGLI TRIO 0.3MG TABLET 10'SArrow

  • The recommended dosage of 'VOGLI TRIO 0.3MG TABLET 10'S' varies significantly depending on individual patient factors, including the severity of their diabetes, their response to treatment, and any other existing medical conditions. Your physician will determine the most appropriate dosage regimen for you.
  • Typically, 'VOGLI TRIO 0.3MG TABLET 10'S' is initiated at a low dose to minimize the risk of gastrointestinal side effects, which are common with voglibose, one of the active ingredients. The initial dose might be 0.2 mg or 0.3 mg, taken once daily with the first main meal. The dosage can then be gradually increased based on your blood glucose levels and tolerance.
  • The maximum recommended daily dose of voglibose is usually 0.6 mg to 0.8 mg, divided into two or three doses taken with meals. It's crucial to adhere to your doctor's instructions regarding the timing and frequency of doses. Do not exceed the prescribed dose without consulting your healthcare provider.
  • It is crucial to monitor your blood glucose levels regularly as directed by your doctor, especially when starting 'VOGLI TRIO 0.3MG TABLET 10'S' or when the dosage is adjusted. This will help ensure that your blood sugar levels are well-controlled and that the medication is working effectively.
  • If you miss a dose of 'VOGLI TRIO 0.3MG TABLET 10'S', take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for a missed one.
  • Take 'VOGLI TRIO 0.3MG TABLET 10'S' only as per the prescription by your physician only

What if I miss my dose of VOGLI TRIO 0.3MG TABLET 10'S?Arrow

  • If you miss a dose of VOGLI TRIO 0.3MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

How to store VOGLI TRIO 0.3MG TABLET 10'S?Arrow

  • Keep VOGLI TRIO 0.3MG TAB 1X10 away from the reach of children and pets.
  • Store VOGLI TRIO 0.3MG TAB 1X10 at room temperature.

Benefits of VOGLI TRIO 0.3MG TABLET 10'SArrow

  • VOGLI TRIO 0.3MG TABLET 10'S is a combination medicine used to effectively manage type 2 diabetes mellitus, particularly in individuals whose blood sugar levels are not adequately controlled by diet, exercise, and single-agent therapy. Its triple combination action addresses multiple facets of glucose regulation, offering a comprehensive approach to glycemic control.
  • One of the primary benefits of VOGLI TRIO is its ability to lower post-prandial blood sugar levels. Voglibose, an alpha-glucosidase inhibitor, works by slowing down the absorption of carbohydrates from the small intestine into the bloodstream. This action helps prevent sharp spikes in blood sugar immediately after meals, a common challenge for people with diabetes.
  • Metformin, a biguanide, enhances insulin sensitivity and decreases hepatic glucose production. By improving how the body utilizes insulin, metformin allows cells to take up glucose more efficiently, thereby lowering blood sugar levels. Additionally, it reduces the amount of glucose produced by the liver, further contributing to glycemic control.
  • The third component, glimepiride, is a sulfonylurea that stimulates the pancreas to release more insulin. This increased insulin secretion helps to lower blood sugar levels, particularly when taken before meals. By combining these three medications, VOGLI TRIO provides a synergistic effect, targeting different mechanisms involved in glucose metabolism to achieve optimal blood sugar control.
  • Beyond glycemic control, VOGLI TRIO offers several additional advantages. Effective management of blood sugar levels can reduce the risk of long-term complications associated with diabetes, such as cardiovascular disease, nerve damage (neuropathy), kidney damage (nephropathy), and eye damage (retinopathy). By maintaining stable blood sugar levels, VOGLI TRIO helps protect vital organs and improves overall health outcomes.
  • VOGLI TRIO can also lead to improvements in HbA1c levels, a measure of average blood sugar control over the past 2-3 months. Lowering HbA1c is crucial for reducing the risk of diabetes-related complications and improving long-term prognosis. Regular monitoring of HbA1c levels, in conjunction with VOGLI TRIO treatment, allows healthcare providers to assess treatment effectiveness and make necessary adjustments.
  • Furthermore, the combination therapy in VOGLI TRIO may reduce the need for multiple medications taken at different times of the day, simplifying the treatment regimen and improving patient adherence. Adherence to medication schedules is essential for achieving optimal therapeutic outcomes in diabetes management. This simplified regimen can lead to better overall management of the condition and improved quality of life.
  • It is important to note that VOGLI TRIO should be used in conjunction with lifestyle modifications, including a healthy diet and regular exercise. These lifestyle changes are fundamental to managing diabetes and maximizing the benefits of medication. Patients should work closely with their healthcare providers to develop a comprehensive diabetes management plan that includes medication, diet, exercise, and regular monitoring of blood sugar levels.

How to use VOGLI TRIO 0.3MG TABLET 10'SArrow

  • VOGLI TRIO 0.3MG TABLET 10'S should be taken exactly as prescribed by your doctor. It's typically recommended to take this medication just before meals, ideally with your first bite. This helps to control the rise in blood sugar levels that occur after eating. The dosage and timing are crucial for optimal effectiveness, so adherence to your doctor's instructions is paramount.
  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this can affect how the medication is released into your system. Consistency is key, so try to take VOGLI TRIO 0.3MG TABLET 10'S at the same time each day to maintain a steady level of medication in your body. Missing doses can lead to fluctuations in your blood sugar levels, potentially diminishing the drug's efficacy.
  • While taking VOGLI TRIO 0.3MG TABLET 10'S, it's important to monitor your blood sugar levels regularly, as directed by your healthcare provider. This will help you and your doctor assess how well the medication is working and make any necessary adjustments to your treatment plan. Also, it is very important to inform your doctor of all other medications you may be taking, including over-the-counter drugs and herbal supplements, to avoid potential drug interactions.
  • Remember that VOGLI TRIO 0.3MG TABLET 10'S is most effective when combined with a healthy diet and regular exercise. Follow your doctor's or a registered dietitian's recommendations for a balanced meal plan that supports stable blood sugar levels. Regular physical activity enhances the body's sensitivity to insulin, further aiding in blood sugar control. Lifestyle modifications are a cornerstone in managing diabetes along with medication. Also, store this medicine in a cool dry place, away from direct sunlight and moisture. Keep it out of reach of children and pets. If you experience any unusual side effects or have concerns about your treatment, contact your doctor promptly.
  • If you forget to take a dose, take it as soon as you remember unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up. Also, if you have kidney or liver disease, or heart problems, consult with your doctor before taking this medication. These conditions may affect how VOGLI TRIO 0.3MG TABLET 10'S works in your body or increase your risk of side effects. Always follow your healthcare provider's advice for safe and effective management of your condition.

Quick Tips for VOGLI TRIO 0.3MG TABLET 10'SArrow

  • Take VOGLI TRIO 0.3MG TABLET 10'S exactly as prescribed by your doctor. Do not change the dosage or stop taking the medication without consulting your healthcare provider. This ensures optimal blood sugar control and minimizes the risk of side effects. Adhering to your doctor's instructions is crucial for managing your diabetes effectively.
  • Monitor your blood sugar levels regularly as directed by your doctor. VOGLI TRIO 0.3MG TABLET 10'S helps to lower blood sugar, but regular monitoring is essential to ensure that your levels are within the target range. Keep a record of your blood sugar readings and share them with your doctor during your appointments. This will help your doctor adjust your treatment plan if needed.
  • Follow a healthy diet and exercise regularly while taking VOGLI TRIO 0.3MG TABLET 10'S. This medication works best when combined with a balanced diet and regular physical activity. Focus on consuming whole grains, fruits, vegetables, and lean protein. Aim for at least 30 minutes of moderate-intensity exercise most days of the week. A healthy lifestyle can significantly improve your blood sugar control and overall health.
  • Be aware of the symptoms of low blood sugar (hypoglycemia) and how to manage them. Symptoms may include shakiness, sweating, confusion, and dizziness. Carry a source of fast-acting sugar, such as glucose tablets or fruit juice, with you at all times. If you experience symptoms of hypoglycemia, consume the fast-acting sugar and check your blood sugar level. Inform your family and friends about the signs of hypoglycemia and how to assist you if needed.
  • Inform your doctor about all other medications, supplements, and herbal products you are taking before starting VOGLI TRIO 0.3MG TABLET 10'S. Certain medications can interact with this medicine and affect its effectiveness or increase the risk of side effects. It is important to provide your doctor with a complete list of all the substances you are taking to ensure safe and effective treatment.

FAQs

What is VOGLI TRIO 0.3MG TABLET 10'S?Arrow

VOGLI TRIO 0.3MG TABLET 10'S is a combination medicine used to control high blood sugar levels in people with type 2 diabetes. It contains three medicines: Voglibose, Metformin and Glimepiride.

What is VOGLI TRIO 0.3MG TABLET 10'S used for?Arrow

VOGLI TRIO 0.3MG TABLET 10'S is used to treat type 2 diabetes mellitus. It helps lower blood sugar levels.

How does VOGLI TRIO 0.3MG TABLET 10'S work?Arrow

VOGLI TRIO 0.3MG TABLET 10'S works in three different ways. Voglibose prevents the rise in blood glucose levels after meals. Metformin decreases the amount of glucose produced by the liver and increases the body's sensitivity to insulin. Glimepiride stimulates the release of insulin from the pancreas.

What are the common side effects of VOGLI TRIO 0.3MG TABLET 10'S?Arrow

Common side effects of VOGLI TRIO 0.3MG TABLET 10'S include nausea, vomiting, diarrhea, abdominal pain, and constipation.

Is VOGLI TRIO 0.3MG TABLET 10'S safe during pregnancy?Arrow

There is not enough information available about the safety of VOGLI TRIO 0.3MG TABLET 10'S during pregnancy. Therefore, consult your doctor before taking this medicine if you are pregnant or planning to become pregnant.

Is VOGLI TRIO 0.3MG TABLET 10'S safe during breastfeeding?Arrow

It is not known whether VOGLI TRIO 0.3MG TABLET 10'S passes into breast milk. Therefore, consult your doctor before taking this medicine if you are breastfeeding.

Is it safe to consume alcohol with VOGLI TRIO 0.3MG TABLET 10'S?Arrow

Consuming alcohol with VOGLI TRIO 0.3MG TABLET 10'S can lower blood sugar levels. Therefore, avoid consuming alcohol while taking this medicine.

What is the dosage of VOGLI TRIO 0.3MG TABLET 10'S?Arrow

The dosage of VOGLI TRIO 0.3MG TABLET 10'S will be determined by your doctor. The dosage may vary depending on your age, weight, health condition, and other medications you are taking.

What happens if I miss a dose of VOGLI TRIO 0.3MG TABLET 10'S?Arrow

If you miss a dose of VOGLI TRIO 0.3MG TABLET 10'S, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose.

How to store VOGLI TRIO 0.3MG TABLET 10'S?Arrow

Store VOGLI TRIO 0.3MG TABLET 10'S at room temperature, away from heat and moisture. Keep it out of reach of children and pets.

Can VOGLI TRIO 0.3MG TABLET 10'S interact with other medications?Arrow

VOGLI TRIO 0.3MG TABLET 10'S can interact with certain other medications, such as insulin, sulfonylureas, and some antibiotics. Therefore, tell your doctor about all the medications you are taking before taking this medicine.

What precautions should I take while taking VOGLI TRIO 0.3MG TABLET 10'S?Arrow

While taking VOGLI TRIO 0.3MG TABLET 10'S, you should check your blood sugar levels regularly and follow a healthy diet and exercise plan. Tell your doctor if you experience any side effects.

Can VOGLI TRIO 0.3MG TABLET 10'S treat type 1 diabetes?Arrow

No, VOGLI TRIO 0.3MG TABLET 10'S is not used to treat type 1 diabetes mellitus. It is only for type 2 diabetes mellitus.

Can I take VOGLI TRIO 0.3MG TABLET 10'S on an empty stomach?Arrow

It is best to take VOGLI TRIO 0.3MG TABLET 10'S with food. This reduces the chance of stomach upset.

Can VOGLI TRIO 0.3MG TABLET 10'S cause weight gain?Arrow

VOGLI TRIO 0.3MG TABLET 10'S can cause weight gain in some people. Talk to your doctor if you experience weight gain while taking this medication.

Are there other brands for Voglibose?Arrow

Yes, there are several other brands for Voglibose. Some common brands include Volibix, Glibose, and Voglitab.

References

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DrugBank: Voglibose. This entry provides comprehensive information on Voglibose, including its mechanism of action, pharmacokinetics, and therapeutic uses. It may indirectly relate to Vogli Trio, as Voglibose is a component.

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Efficacy and safety of voglibose 0.2 mg three times daily versus placebo in Japanese patients with type 2 diabetes mellitus treated with diet and exercise: A randomized, double-blind, placebo-controlled trial. This research article examines the efficacy of Voglibose in managing type 2 diabetes, relevant as Vogli Trio contains Voglibose.

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FDA Approved Drug Products. This is the official website of the US Food and Drug Administration for approved drug products. Please use the search function within the website and look for Metformin and/or Glimepiride for detailed drug information.

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European Medicines Agency (EMA) - Amaryl. This provides detailed information on Glimepiride (Amaryl), including its pharmacology and clinical efficacy. Glimepiride is a component of Vogli Trio.

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Metformin: An Old but Still the Best Treatment for Type 2 Diabetes. This paper reviews the role and mechanism of action of Metformin in treating type 2 diabetes, which is one of the components in the Vogli Trio.

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ScienceDirect - This database can be used to search for research articles related to Voglibose, Metformin, and Glimepiride, the ingredients in Vogli Trio. Use keywords like "Voglibose clinical trials," "Metformin mechanism," and "Glimepiride pharmacokinetics."

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