XULTOPHY DISPOPEN 3 ML

How XULTOPHY DISPOPEN 3 ML Works

• XULTOPHY DISPOPEN 3 ML is a combination medicine containing insulin degludec and liraglutide. These two active ingredients work together to improve blood sugar control in adults with type 2 diabetes.
• Insulin degludec is a long-acting basal insulin that helps to lower blood sugar levels throughout the day and night. It works by replacing the insulin that your body should be producing. Insulin allows sugar (glucose) from the blood to enter cells, where it is used for energy. In type 2 diabetes, the body either doesn't produce enough insulin or the cells don't respond properly to insulin, leading to high blood sugar levels. Insulin degludec has a slow and steady release, providing a more stable and predictable effect compared to older insulins, reducing the risk of hypoglycemia (low blood sugar).
• Liraglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist. It works through several mechanisms. First, it enhances insulin release from the pancreas when blood sugar levels are high. Second, it decreases the amount of sugar produced by the liver. Third, it slows down the emptying of the stomach, which can help to reduce appetite and food intake, potentially leading to weight loss. By mimicking the effects of the natural GLP-1 hormone, liraglutide helps to improve blood sugar control in a glucose-dependent manner, meaning its effects are more pronounced when blood sugar is high and less so when blood sugar is normal.
• In essence, XULTOPHY DISPOPEN 3 ML combines the sustained blood sugar lowering action of a basal insulin with the additional benefits of a GLP-1 receptor agonist, such as improved insulin secretion, reduced liver glucose production, and appetite regulation. This dual action helps to achieve better overall glycemic control compared to using either insulin or a GLP-1 receptor agonist alone. It's important to use XULTOPHY DISPOPEN 3 ML exactly as prescribed by your doctor and to follow their instructions regarding diet, exercise, and blood sugar monitoring. Regular monitoring will help you and your doctor determine how well the medication is working and make any necessary adjustments to your treatment plan. Talk to your doctor or pharmacist if you have any questions about how XULTOPHY DISPOPEN 3 ML works or how to use it properly.

Common side effects of Xultophy (insulin degludec and liraglutide) may include: * **Hypoglycemia (low blood sugar):** This is the most common side effect, especially when Xultophy is used with other diabetes medications. Symptoms can include shakiness, sweating, rapid heartbeat, blurred vision, dizziness, and confusion. * **Gastrointestinal issues:** Nausea, diarrhea, vomiting, constipation, and abdominal pain are frequently reported. * **Decreased appetite:** Xultophy can sometimes reduce your appetite. * **Headache** * **Upper respiratory tract infections:** Such as the common cold. * **Injection site reactions:** Redness, pain, or itching at the injection site may occur. Less common, but more serious side effects may include: * **Pancreatitis:** Inflammation of the pancreas, which can cause severe abdominal pain, nausea, and vomiting. * **Gallbladder problems:** Including gallstones and cholecystitis (inflammation of the gallbladder). * **Kidney problems:** Xultophy can sometimes affect kidney function. * **Severe allergic reactions:** Rash, itching, swelling, difficulty breathing, or a rapid heartbeat. * **Increased heart rate:** Xultophy can cause a slight increase in heart rate. * **Hypersensitivity reactions:** Other allergic reactions, such as urticaria (hives) and angioedema (swelling under the skin). * **Thyroid tumors or cancer:** In animal studies, liraglutide (one of the active ingredients in Xultophy) has been associated with an increased risk of thyroid tumors. It is unknown if this risk exists in humans. It is important to contact your doctor immediately if you experience any serious side effects or symptoms that concern you.

• If you miss a dose of Xultophy, take it as soon as you remember, unless it is close to the time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule.
• Do not take a double dose to make up for the missed dose.
• If you are not sure what to do, contact your doctor or pharmacist for advice.

• Keep XULTOPHY DISPOPEN 3ML away from the reach of children and pets.
• Store XULTOPHY DISPOPEN 3ML in a refrigerator (2 - 8°C). Do not freeze.

• Xultophy is a combination medicine containing insulin degludec and liraglutide, used to improve blood sugar control in adults with type 2 diabetes. It's administered as a once-daily injection.
• Always follow your doctor's instructions carefully regarding dosage and timing of Xultophy injections. Do not adjust the dose without consulting your healthcare provider.
• Inject Xultophy under the skin (subcutaneously) of your stomach area (abdomen), thigh, or upper arm. Rotate injection sites to prevent skin thickening or pitting.
• Monitor your blood sugar levels regularly as directed by your doctor, especially when starting Xultophy or changing the dosage. This helps ensure the medication is working effectively.
• Be aware of the symptoms of low blood sugar (hypoglycemia), such as sweating, shakiness, confusion, and dizziness. Carry a source of fast-acting sugar (like glucose tablets or juice) with you in case your blood sugar drops too low.
• If you experience any symptoms of a serious allergic reaction, such as rash, itching, swelling, severe dizziness, or trouble breathing, seek immediate medical attention.
• Xultophy may cause gastrointestinal side effects like nausea, vomiting, or diarrhea. These side effects are usually mild and temporary, but contact your doctor if they persist or worsen.
• Inform your doctor about all other medications you are taking, including over-the-counter drugs, vitamins, and herbal supplements, as they may interact with Xultophy.
• Store Xultophy in the refrigerator (36°F to 46°F [2°C to 8°C]) until first use. After first use, the pen can be stored at room temperature (below 86°F [30°C]) for up to 21 days. Do not freeze.
• Carefully dispose of used Xultophy pens in a sharps container to prevent accidental needle sticks. Follow your local guidelines for proper disposal.
• Remember, Xultophy is part of a comprehensive diabetes management plan that includes diet and exercise. Continue to follow your doctor's recommendations for a healthy lifestyle.
• When using a new Xultophy pen, always prime the pen before your first injection. This ensures the pen is working properly and delivers the correct dose.
• Check the Xultophy pen before each injection to make sure the insulin solution is clear and colorless. Do not use the pen if the solution is cloudy, colored, or contains particles.
• If you miss a dose of Xultophy, take it as soon as you remember, unless it's almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
• Keep Xultophy and all other medications out of reach of children. Accidental injection can be very dangerous.
• Xultophy can be used with other diabetes medications as prescribed by your doctor. However, you should inform your doctor about all medications you are taking to avoid potential drug interactions.
• If you are planning to travel, make sure to pack enough Xultophy and any necessary supplies, such as needles and a sharps container. Keep Xultophy in its original packaging and consider carrying a copy of your prescription.
• During hot weather, protect your Xultophy pen from direct sunlight and extreme temperatures. High temperatures can damage the medication and affect its effectiveness.
• Before starting Xultophy, discuss any existing medical conditions with your doctor, especially if you have a history of pancreatitis, kidney problems, or severe stomach problems.
• Attend regular check-ups with your doctor to monitor your blood sugar levels and overall health while taking Xultophy. These appointments are essential for managing your diabetes effectively.

• Xultophy has no known interactions with food. You can take Xultophy at any time, regardless of your meals. However, it is important to maintain a consistent eating pattern and carbohydrate intake throughout the day.
• Always follow your doctor's or healthcare provider's advice regarding diet and lifestyle while taking Xultophy.