ZAVEDOS 5MG INJECTION
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ZAVEDOS 5MG INJECTION
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ZAVEDOS 5MG INJECTION

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ZAVEDOS 5MG INJECTION

By PFIZER PHARMACEUTICAL INDIA PRIVATE LIMITED

MRP

8900

₹7565

15 % OFF

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Composition

Product DetailsArrow

Content Reviewed By:

Dr. Neha Patel

, (MBBS)

Written By:

Mr. Ankit Jain

, (B.Pharm)

About ZAVEDOS 5MG INJECTION

  • ZAVEDOS 5MG INJECTION contains the active substance Idarubicin hydrochloride, an antineoplastic drug belonging to the anthracycline class. It's prescribed for both adults and children in the treatment of acute non-lymphoblastic leukemia (ANLL), also known as acute myeloid leukemia (AML). Furthermore, it serves as a second-line treatment for relapsed acute lymphoblastic leukemia (ALL) in both adult and pediatric patients. This medication functions by inhibiting or significantly slowing down the proliferation of cancer cells within the body, thereby combating the disease's progression.
  • Before using ZAVEDOS 5MG INJECTION, inform your doctor if you have any allergies to Idarubicin or any of the other ingredients in the medicine. It's crucial to disclose any pre-existing medical conditions such as infections, liver disease, kidney disease, or heart disorders, as well as any stomach problems or if you are currently breastfeeding. If you have been informed by your doctor about any sugar intolerances, discuss this with them before commencing treatment with this medicine. Special caution should be taken in such cases to ensure the medicine is suitable for your condition.
  • ZAVEDOS 5MG INJECTION is strictly contraindicated during pregnancy and breastfeeding. If you are pregnant, suspect you might be pregnant, or are breastfeeding, inform your doctor immediately. Women of childbearing potential must use effective contraception throughout the treatment period to prevent pregnancy. This medication may also impact male fertility, so if you are planning to conceive, discuss this with your doctor beforehand. Common side effects associated with this medication include diarrhea, nausea, vomiting, stomach cramps, and hair loss. Report any severe or persistent side effects to your doctor promptly. It's important to manage these side effects effectively to ensure continuation of the treatment.
  • During treatment with ZAVEDOS 5MG INJECTION, regular monitoring of blood counts and liver and kidney function is crucial to ensure the medication is not causing significant toxicity. Your doctor will adjust the dosage or discontinue the treatment if necessary, based on the test results and your overall condition. Hydration is important during the therapy to help alleviate some of the side effects and support kidney function. It is also advisable to avoid live vaccines during treatment, as ZAVEDOS 5MG INJECTION can weaken the immune system, increasing the risk of infection from the vaccine.
  • It is important to maintain open communication with your healthcare provider about any other medications or supplements you are taking, as they may interact with ZAVEDOS 5MG INJECTION. Avoid alcohol during the treatment, as it can exacerbate some of the side effects, especially nausea and liver problems. Follow your doctor's instructions carefully regarding the dosage and administration schedule, and do not stop taking the medication without consulting them, even if you start to feel better.

Uses of ZAVEDOS 5MG INJECTION

  • Acute myeloid leukemia (AML), a rapidly progressing cancer of the blood and bone marrow, impacting the production of normal blood cells.
  • Relapsed acute lymphoblastic leukemia (ALL), referring to the return of ALL after a period of remission, requiring further treatment strategies.

Side Effects of ZAVEDOS 5MG INJECTIONArrow

Side effects are unwanted symptoms caused by medicines, though not everyone experiences them. Common side effects include: Hair loss, Itchy skin rash, Diarrhea, Nausea, vomiting, Stomach cramps, Headache. Serious side effects include: Abnormal rhythm, Chest pain, Congestive heart failure, Decreased bone marrow function, Liver toxicity, Kidney toxicity, Infections.

  • Hair loss
  • Itchy skin rash
  • Diarrhea
  • Nausea, vomiting
  • Stomach cramps
  • Headache
  • Abnormal rhythm
  • Chest pain
  • Congestive heart failure
  • Decreased bone marrow function
  • Liver toxicity
  • Kidney toxicity
  • Infections

Safety Advice for ZAVEDOS 5MG INJECTIONArrow

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Pregnancy

UNSAFE

ZAVEDOS 5MG INJECTION is unsafe to administer in pregnant women because it may affect the fetus. Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant. Using an effective birth control method during the treatment and for 6.5 months after your last dose is necessary.

Dosage of ZAVEDOS 5MG INJECTIONArrow

  • ZAVEDOS 5MG INJECTION will be administered to you by a qualified healthcare professional, such as a doctor or nurse, in a hospital or clinic environment. These professionals are specifically trained in the administration of cancer chemotherapy.
  • The medication is delivered via intravenous infusion, which means it's administered directly into your vein through a drip. It is crucial that you do not attempt to self-administer this injection. The dosage and duration of your treatment will be determined by your doctor, who will consider several factors.
  • These factors include the severity of your condition, your body weight, and other individual health considerations. Your doctor will carefully assess your overall health profile to determine the most appropriate and effective dosage schedule for you. Following the prescribed dosage and duration is essential for achieving the best possible outcome from the treatment.

How to store ZAVEDOS 5MG INJECTION?Arrow

  • Keep ZAVEDOS 5MG INJ away from the reach of children and pets.
  • Store ZAVEDOS 5MG INJ at room temperature.

Benefits of ZAVEDOS 5MG INJECTIONArrow

  • ZAVEDOS 5MG INJECTION is a powerful medication used in the treatment of various cancers. It works by interfering with the way cancer cells grow and multiply, ultimately slowing down or stopping the progression of the disease. This injection contains a substance that exhibits both antimitotic and cytotoxic effects, meaning it can prevent cells from dividing and also directly kill cancer cells. Its mechanism of action is multifaceted, involving interactions with DNA and the enzyme topoisomerase II.
  • Specifically, ZAVEDOS 5MG INJECTION intercalates with DNA, forming complexes that disrupt the normal function of the DNA molecule. Additionally, it inhibits the activity of topoisomerase II, an enzyme crucial for DNA replication and repair. By stabilizing the DNA-topoisomerase II complex, the drug effectively blocks the relegation component of the ligation-religation reaction, further hindering cancer cell growth. This comprehensive approach makes ZAVEDOS 5MG INJECTION a valuable tool in cancer therapy.
  • It is essential to remember that ZAVEDOS 5MG INJECTION is a potent drug and should only be administered under the close supervision of a qualified healthcare professional. The dosage and treatment schedule will be determined based on the individual patient's condition, the type of cancer being treated, and other factors. Patients should discuss any concerns or potential side effects with their doctor or pharmacist before starting treatment.

How to use ZAVEDOS 5MG INJECTIONArrow

  • ZAVEDOS 5MG INJECTION will be administered to you by a qualified healthcare professional, such as a doctor or nurse, in a hospital or clinic setting. These professionals are specifically trained in the administration of cancer chemotherapy.
  • The medication is delivered intravenously, meaning it is given through a drip directly into your vein. This method ensures the drug is absorbed efficiently into your bloodstream.
  • It is crucial to understand that ZAVEDOS 5MG INJECTION should never be self-administered. Attempting to do so could lead to serious complications.
  • Your doctor will carefully determine the appropriate dosage and the duration of your treatment. This decision will be based on several factors, including the severity of your condition, your body weight, and other individual health considerations. Following your doctor's instructions precisely is vital for the effectiveness and safety of your treatment.
  • During the infusion, you will be closely monitored by the healthcare team to watch for any potential side effects or adverse reactions. If you experience any discomfort or unusual symptoms during the administration, inform your nurse or doctor immediately.

FAQs

Can I take vitamin supplements with ZAVEDOS 5MG INJECTION?Arrow

Certain medications may interact with the effectiveness of ZAVEDOS 5MG INJECTION including prescription, over-the-counter medicines, vitamin or nutritional supplements, and herbal products. Inform your physician about your medication history.

Is ZAVEDOS 5MG INJECTION cardiotoxic?Arrow

Heart problems like cardiac arrest, abnormal heart rhythm, and congestive heart failure may occur in patients receiving this medicine for the long term. Inform your physician if you have any pre-existing heart disorders before initiating the treatment.

Does ZAVEDOS 5MG INJECTION cause hair loss?Arrow

Hair loss is a common side effect of ZAVEDOS 5MG INJECTION. Consult your doctor if you have more hair fall.

Is ZAVEDOS 5MG INJECTION an antibiotic?Arrow

ZAVEDOS 5MG INJECTION is an anthracycline antibiotic, an anti-cancer drug used to treat certain types of cancer.

Is ZAVEDOS 5MG INJECTION a Vesicant?Arrow

Vesicants are drugs that can result in tissue necrosis or the formation of blisters (irritation and ulceration of surrounding tissue) when accidentally infused into tissue surrounding a vein. This medicine is classified as a vesicant, hence it will be carefully administered to you by the healthcare professional.

NULL interaction of ZAVEDOS 5MG INJECTION with other drungsArrow

Information regarding the interaction of ZAVEDOS 5MG INJECTION with other drugs is not available.

What precautions should I take while taking ZAVEDOS 5MG INJECTION?Arrow

Male patient with a female partner of reproductive potential to use effective contraception during the therapy and for 3.5 months after the last dose. Report symptoms of infection, anemia, or bleeding immediately to your doctor. Do not breastfeed during the treatment and for 14 days after the last dose. This medicine may cause infertility in both men and women, inform your doctor if you are planning for pregnancy before initiating the treatment. This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often. Your doctor may advise you to take certain tests to check for the effectiveness of the therapy.

What molecule/combination is used for making ZAVEDOS 5MG INJECTION?Arrow

ZAVEDOS 5MG INJECTION is made from IDARUBICIN molecule.

For what ailments/diseases/conditions is ZAVEDOS 5MG INJECTION prescribed?Arrow

ZAVEDOS 5MG INJECTION is prescribed for ailments/diseases/conditions related to Oncology.

References

Book Icon

Zavedos 5mg Powder for Solution for Injection - Summary of Product Characteristics (SmPC) - (emc). www.medicines.org.uk.

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Idamycin - Idarubicin hydrochloride

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Cersosimo RJ. Idarubicin: an anthracycline antineoplastic agent. Clinical Pharmacy.;11(2):152–67.

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Good service, cheaper medicine and better quality and effective.

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Reviewed on 27-07-2023

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Gotri Medkart Pharmacy providing generic medicines & other products with affordable price with better service.

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Reviewed on 11-01-2024

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Best for medicine and helpfull.😊

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medkart pharmacy medicine is very nice 👍

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Reviewed on 27-11-2023

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(5/5)

Geniune medicines available at good discounts

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Reviewed on 05-12-2022

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(5/5)


Marketer / Manufacturer Details

PFIZER PHARMACEUTICAL INDIA PRIVATE LIMITED

Country of Origin -

India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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