ZERODOL TC TABLET 10'S

How ZERODOL TC TABLET 10'S Works

• ZERODOL TC TABLET 10'S is a combination medicine designed to alleviate pain and inflammation. It combines two active ingredients: Aceclofenac and Tizanidine, each working through different mechanisms to provide comprehensive relief.
• Aceclofenac, a non-steroidal anti-inflammatory drug (NSAID), primarily targets the cyclooxygenase (COX) enzymes. These enzymes are crucial in the production of prostaglandins, which are key mediators of pain, inflammation, and fever. By inhibiting COX enzymes, Aceclofenac reduces the synthesis of prostaglandins, thereby diminishing pain and inflammation at the affected site. This action helps to reduce swelling, redness, and tenderness, making movement more comfortable.
• Tizanidine, on the other hand, is a muscle relaxant that acts centrally within the spinal cord and brain. It is an alpha-2 adrenergic agonist, meaning it binds to and activates alpha-2 adrenergic receptors. This activation reduces the release of excitatory neurotransmitters in the spinal cord, which are responsible for transmitting pain signals and maintaining muscle tone. By decreasing the activity of these neurotransmitters, Tizanidine helps to reduce muscle spasticity, muscle spasms, and associated pain. This results in muscle relaxation, improved mobility, and decreased discomfort.
• The combined action of Aceclofenac and Tizanidine in ZERODOL TC TABLET 10'S provides synergistic benefits. Aceclofenac addresses the inflammatory component of pain, while Tizanidine tackles muscle-related pain and spasms. This dual action makes ZERODOL TC TABLET 10'S particularly effective in conditions where pain and muscle stiffness coexist, such as back pain, sprains, and strains. The medication not only reduces pain and inflammation but also helps to restore normal muscle function and improve overall comfort.
• In summary, ZERODOL TC TABLET 10'S works by targeting both the inflammatory pathways and the central nervous system to relieve pain and muscle spasms. Aceclofenac inhibits prostaglandin production to reduce inflammation, while Tizanidine acts on alpha-2 adrenergic receptors in the spinal cord to relax muscles. Together, they provide comprehensive relief from pain, inflammation, and muscle stiffness, promoting improved mobility and comfort.

Common side effects of Zerodol TC Tablet may include nausea, vomiting, stomach pain, heartburn, diarrhea, constipation, loss of appetite, dizziness, drowsiness, headache, skin rash, and increased liver enzymes. Uncommon side effects may include peptic ulcers, bleeding gums, blurred vision, fluid retention (edema), high blood pressure, and allergic reactions like angioedema (swelling under the skin). Rare but serious side effects can include liver damage, kidney problems, severe skin reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis), and blood disorders.

• If you miss a dose of Zerodol TC Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep ZERODOL TC TAB 1X10 away from the reach of children and pets.
• Store ZERODOL TC TAB 1X10 at room temperature.

• Take ZERODOL TC TABLET 10'S exactly as prescribed by your doctor. Do not exceed the recommended dosage or duration. Overuse can lead to serious side effects, while underuse may not provide adequate relief. It is crucial to follow the prescribed regimen to manage your condition effectively.
• ZERODOL TC TABLET 10'S is often prescribed to manage pain and inflammation associated with conditions like osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. It can also be used for post-operative pain relief. Understanding the specific reason for your prescription helps you appreciate its role in your treatment plan.
• If you have a history of stomach ulcers, bleeding disorders, or heart problems, inform your doctor before starting ZERODOL TC TABLET 10'S. This medication can increase the risk of gastrointestinal bleeding or cardiovascular events in susceptible individuals. Your doctor will assess the risks and benefits to determine if it's suitable for you.
• Avoid taking ZERODOL TC TABLET 10'S with other NSAIDs (non-steroidal anti-inflammatory drugs) like ibuprofen or naproxen, as this can increase the risk of side effects, especially gastrointestinal issues. Always inform your doctor about all the medications you are currently taking, including over-the-counter drugs and herbal supplements, to prevent potential interactions.
• Be aware of potential side effects, such as stomach pain, nausea, heartburn, diarrhea, or constipation. If you experience severe or persistent side effects, such as black stools, vomiting blood, chest pain, or difficulty breathing, seek immediate medical attention. Early reporting of side effects can prevent serious complications. Regular monitoring by your healthcare provider can help manage these effects effectively.

• ZERODOL TC TABLET 10'S may be taken with or without food, but it is generally recommended to take it after food to avoid stomach upset. Consult your doctor for specific advice.