ZEVTAZ INFU VIAL 1'S

How ZEVTAZ INFU VIAL 1'S Works

• ZEVTAZ INFU VIAL 1'S is a powerful antibiotic combination designed to combat a wide range of bacterial infections. It contains two active ingredients: Ceftazidime and Avibactam. Ceftazidime is a cephalosporin antibiotic, which belongs to the beta-lactam class. It works by interfering with the synthesis of the bacterial cell wall. Specifically, it inhibits the enzymes responsible for building the peptidoglycan layer, a crucial component of the bacterial cell wall. By disrupting this process, ceftazidime weakens the cell wall, eventually leading to bacterial cell death.
• However, many bacteria have developed resistance mechanisms to beta-lactam antibiotics like ceftazidime. One of the most common mechanisms is the production of beta-lactamase enzymes. These enzymes break down the beta-lactam ring in the antibiotic molecule, rendering it ineffective. This is where Avibactam comes in. Avibactam is a non-beta-lactam beta-lactamase inhibitor. It binds to beta-lactamase enzymes, preventing them from breaking down ceftazidime. By inhibiting beta-lactamases, avibactam restores ceftazidime's ability to effectively kill bacteria.
• In essence, ZEVTAZ INFU VIAL 1'S provides a two-pronged attack against bacterial infections. Ceftazidime targets the bacterial cell wall, while Avibactam protects ceftazidime from being inactivated by bacterial resistance mechanisms. This combination makes ZEVTAZ INFU VIAL 1'S effective against many bacteria that are resistant to ceftazidime alone, including many Gram-negative bacteria like Klebsiella pneumoniae, Escherichia coli, and Pseudomonas aeruginosa. This dual action ensures a more comprehensive and potent antibacterial effect, improving the chances of successful treatment, particularly in cases where bacteria have developed resistance to other antibiotics. The synergistic action of ceftazidime and avibactam widens the spectrum of antibacterial activity, making ZEVTAZ INFU VIAL 1'S a valuable tool in combating complicated infections.

Like all medicines, ZEVTAZ INFU VIAL 1'S can cause side effects, although not everybody gets them. **Common side effects (may affect up to 1 in 10 people):** * Diarrhea * Nausea * Vomiting * Headache * Injection site reactions (pain, redness, swelling) * Abnormal liver function tests * Rash * Itching * Fever **Uncommon side effects (may affect up to 1 in 100 people):** * Clostridium difficile-associated diarrhea * Fungal infections (e.g., oral thrush) * Abdominal pain * Loss of appetite * Inflammation of the veins (phlebitis) * Low blood potassium * Anxiety * Insomnia * Dizziness * Seizures * Low blood pressure * Difficulty breathing * Hives * Increased sweating * Muscle cramps * Kidney problems * Blood disorders (e.g., anemia, thrombocytopenia, leukopenia) **Rare side effects (may affect up to 1 in 1,000 people):** * Severe allergic reactions (anaphylaxis) * Stevens-Johnson syndrome * Toxic epidermal necrolysis * Drug reaction with eosinophilia and systemic symptoms (DRESS) * Liver failure **If you experience any severe side effects, such as difficulty breathing, swelling of the face or throat, or a severe skin rash, seek immediate medical attention.** This is not an exhaustive list. Consult your doctor or pharmacist for more information.

• If you miss a dose of ZEVTAZ, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you have any concerns, please consult your healthcare provider.

• Keep ZEVTAZ INFU VIAL away from the reach of children and pets.
• Store ZEVTAZ INFU VIAL at room temperature.

• Complete the Full Course: Even if you start feeling better before the course of ZEVTAZ INFU VIAL 1'S is finished, it's crucial to complete the entire prescribed course. Stopping early can lead to antibiotic resistance, making the infection harder to treat in the future, and may cause a relapse of the infection. This ensures all the bacteria are eradicated, preventing recurrence.
• Stay Hydrated: While on ZEVTAZ INFU VIAL 1'S, drink plenty of fluids, especially water. Staying hydrated helps your body flush out the infection and reduces the risk of side effects. Adequate hydration also supports kidney function, which is important during antibiotic treatment. Aim for at least 8-10 glasses of water per day, unless your doctor advises otherwise.
• Report Any Side Effects: Be vigilant about monitoring your body for any side effects while taking ZEVTAZ INFU VIAL 1'S. Common side effects might include nausea, diarrhea, or rash. If you experience any unusual or severe symptoms, such as difficulty breathing, severe abdominal pain, or signs of an allergic reaction (hives, swelling), contact your doctor immediately. Prompt reporting can help manage side effects effectively.
• Inform Your Doctor About All Medications: Before starting ZEVTAZ INFU VIAL 1'S, inform your doctor about all other medications you are currently taking, including over-the-counter drugs, herbal supplements, and vitamins. Some medications can interact with ZEVTAZ INFU VIAL 1'S, potentially reducing its effectiveness or increasing the risk of side effects. This includes blood thinners, certain diuretics, and other antibiotics.
• Probiotics May Help: Antibiotics like ZEVTAZ INFU VIAL 1'S can sometimes disrupt the natural balance of bacteria in your gut, leading to diarrhea or yeast infections. Taking a probiotic supplement during and after your antibiotic course may help restore the balance of gut flora. Consult with your doctor or pharmacist to choose a suitable probiotic and determine the appropriate dosage and timing.
• Proper Storage of Vial: If applicable and if you are administering at home per medical professional instructions, ensure the ZEVTAZ INFU VIAL 1'S is stored according to the instructions provided by your pharmacist or healthcare provider. Typically, this involves storing the vial in a cool, dry place away from direct sunlight and heat. Incorrect storage can affect the medication's potency.

• ZEVTAZ INFU VIAL 1'S is administered intravenously and does not typically interact with food. You can maintain your regular diet while receiving this medication. If you have any specific dietary restrictions or concerns, please discuss them with your doctor or healthcare provider.