ZITA DM 20/1000MG TABLET 15'S
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ZITA DM 20/1000MG TABLET 15'S
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ZITA DM 20/1000MG TABLET 15'S

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ZITA DM 20/1000MG TABLET 15'S

By GLENMARK PHARMACEUTICALS LIMITED

MRP

225

₹191.25

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Product DetailsArrow

About ZITA DM 20/1000MG TABLET 15'S

  • ZITA DM 20/1000mg Tablet is a combination medication designed to effectively manage blood sugar levels in individuals with type 2 diabetes. This tablet combines two powerful active ingredients: Sitagliptin and Metformin. Sitagliptin belongs to a class of drugs known as DPP-4 inhibitors, which work by increasing the release of insulin after a meal and decreasing the amount of sugar produced by the liver. Metformin, a biguanide, primarily works by reducing glucose production in the liver and improving insulin sensitivity in the body's tissues.
  • The combination of these two medications offers a dual approach to managing blood sugar levels, addressing different mechanisms that contribute to hyperglycemia in type 2 diabetes. By enhancing insulin secretion and improving insulin utilization, ZITA DM 20/1000mg Tablet helps maintain stable blood sugar levels throughout the day. This can lead to better glycemic control and a reduced risk of long-term complications associated with diabetes, such as nerve damage, kidney disease, and heart problems.
  • This medication is typically prescribed as part of a comprehensive diabetes management plan that includes diet and exercise. It is important to take ZITA DM 20/1000mg Tablet as directed by your healthcare provider and to follow their recommendations for lifestyle modifications. Regular monitoring of blood sugar levels is also crucial to ensure the medication is effectively managing your diabetes. Always consult with your doctor or pharmacist if you have any questions or concerns about this medication.

Uses of ZITA DM 20/1000MG TABLET 15'S

  • Treatment of type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Improving blood sugar control
  • Enhancing insulin sensitivity
  • Reducing post-meal blood sugar levels
  • Slowing the progression of kidney disease (due to diabetes)
  • Reducing the risk of heart disease (in diabetic patients)

How ZITA DM 20/1000MG TABLET 15'S Works

  • ZITA DM 20/1000MG TABLET 15'S is a combination medication designed to manage blood sugar levels in individuals with type 2 diabetes. It combines two active ingredients: Sitagliptin and Metformin, each working through different mechanisms to achieve optimal glycemic control.
  • Sitagliptin belongs to a class of drugs called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors). DPP-4 is an enzyme that breaks down incretin hormones in the body. Incretin hormones, such as GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide), play a crucial role in regulating blood sugar levels. They stimulate insulin release from the pancreas when blood sugar is high and reduce the secretion of glucagon, a hormone that raises blood sugar levels. By inhibiting DPP-4, Sitagliptin increases the levels of active incretin hormones in the body. This leads to increased insulin secretion and decreased glucagon secretion in a glucose-dependent manner. This means that Sitagliptin primarily works when blood sugar levels are elevated, reducing the risk of hypoglycemia (low blood sugar).
  • Metformin, on the other hand, is a biguanide that works primarily by decreasing glucose production in the liver. The liver is a major source of glucose production, especially during fasting states. Metformin reduces hepatic glucose output by suppressing gluconeogenesis (the formation of glucose from non-carbohydrate sources) and glycogenolysis (the breakdown of glycogen into glucose). Additionally, Metformin improves insulin sensitivity in peripheral tissues, such as muscles. This means that cells become more responsive to insulin, allowing them to uptake glucose more efficiently from the bloodstream. Furthermore, Metformin slows down the absorption of glucose from the intestines, which helps to prevent rapid spikes in blood sugar after meals.
  • When Sitagliptin and Metformin are combined in ZITA DM 20/1000MG TABLET 15'S, they provide a complementary approach to managing blood sugar levels. Sitagliptin enhances insulin secretion and reduces glucagon secretion, while Metformin reduces glucose production in the liver and improves insulin sensitivity. This dual action helps to lower both fasting and postprandial (after-meal) blood sugar levels more effectively than either medication alone. This combination therapy is often prescribed when diet, exercise, and single-agent medications like Metformin are not sufficient to achieve target blood sugar levels. It's important to take ZITA DM 20/1000MG TABLET 15'S as prescribed by your healthcare provider, along with following a healthy diet and regular exercise plan, to effectively manage your type 2 diabetes.
  • In summary, ZITA DM works by enhancing your body's own ability to lower blood sugar by increasing insulin release and decreasing glucagon secretion via Sitagliptin, while Metformin reduces glucose production in the liver and increases sensitivity to the insulin your body produces. This synergistic effect helps keep blood sugar levels within a healthy range.

Side Effects of ZITA DM 20/1000MG TABLET 15'SArrow

The most common side effects of ZITA DM 20/1000mg Tablet may include nausea, vomiting, diarrhea, stomach pain, loss of appetite, and metallic taste. Other possible side effects are headache, dizziness, fatigue, weakness, constipation, upper respiratory tract infection, sore throat, stuffy or runny nose. Serious but less frequent side effects may involve lactic acidosis (symptoms include feeling very weak, tired or uncomfortable, unusual muscle pain, trouble breathing, stomach pain with nausea and vomiting, feeling cold, irregular heartbeat or dizziness), allergic reactions (rash, itching, swelling), hypoglycemia (low blood sugar), and liver problems. In rare cases, it can also cause pancreatitis or vitamin B12 deficiency. Contact your doctor immediately if you experience any severe or persistent side effects.

Safety Advice for ZITA DM 20/1000MG TABLET 15'SArrow

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Allergies

Allergies

Do not use ZITA DM 20/1000MG TABLET 15'S if you are allergic to it.

Dosage of ZITA DM 20/1000MG TABLET 15'SArrow

  • The recommended dosage of 'ZITA DM 20/1000MG TABLET 15'S' varies significantly depending on individual patient factors, including the severity of diabetes, kidney function, other medications being taken, and individual response to treatment. Your physician will determine the appropriate dosage based on a thorough evaluation. Typically, 'ZITA DM 20/1000MG TABLET 15'S' is taken once or twice daily with meals to help reduce gastrointestinal side effects and optimize blood sugar control.
  • It's crucial to adhere strictly to the prescribed dosage and timing. Do not exceed the recommended dose or take it more frequently than directed. Doing so can increase the risk of side effects without providing additional benefit. Similarly, do not skip doses or discontinue 'ZITA DM 20/1000MG TABLET 15'S' without consulting your doctor, as this can lead to a loss of blood sugar control.
  • The dosage may be adjusted by your doctor over time based on your blood glucose levels and overall health. Regular monitoring of blood sugar is essential to determine the effectiveness of the medication and to guide dosage adjustments. Report any side effects or concerns to your doctor promptly. This medicine is typically used as part of a comprehensive diabetes management plan that includes diet and exercise. Take 'ZITA DM 20/1000MG TABLET 15'S' only as per the prescription by your physician only.
  • If you miss a dose of 'ZITA DM 20/1000MG TABLET 15'S', take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for a missed one.
  • The maximum daily dose should not be exceeded. Always consult your healthcare provider for any questions or concerns regarding your dosage. They can provide personalized advice based on your specific medical condition and treatment plan.

What if I miss my dose of ZITA DM 20/1000MG TABLET 15'S?Arrow

  • If you miss a dose of ZITA DM 20/1000MG TABLET 15'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double your dose to make up for the missed one.

How to store ZITA DM 20/1000MG TABLET 15'S?Arrow

  • Keep ZITA DM 20/1000MG TAB 1X15 away from the reach of children and pets.
  • Store ZITA DM 20/1000MG TAB 1X15 at room temperature.

Benefits of ZITA DM 20/1000MG TABLET 15'SArrow

  • ZITA DM 20/1000MG TABLET 15'S offers a dual-action approach to managing type 2 diabetes, combining a DPP-4 inhibitor (Sitagliptin) and a biguanide (Metformin) for comprehensive glycemic control. This synergistic combination helps to lower blood sugar levels effectively by addressing multiple aspects of the disease.
  • Sitagliptin, the DPP-4 inhibitor component, works by increasing the levels of incretin hormones in the body. These hormones stimulate the release of insulin after a meal and reduce the secretion of glucagon, a hormone that raises blood sugar levels. By enhancing incretin activity, ZITA DM 20/1000MG helps to improve insulin secretion in response to elevated blood glucose and suppress glucagon release, leading to better postprandial glucose control.
  • Metformin, the biguanide component, primarily works by decreasing glucose production in the liver and improving insulin sensitivity in peripheral tissues, such as muscles. It also reduces the absorption of glucose from the intestines. By reducing hepatic glucose output and enhancing insulin sensitivity, Metformin helps to lower fasting blood sugar levels and improve overall glycemic control.
  • The combined action of Sitagliptin and Metformin in ZITA DM 20/1000MG provides several key benefits for individuals with type 2 diabetes. Firstly, it effectively lowers both fasting and postprandial blood sugar levels, helping to achieve and maintain target HbA1c levels. Secondly, it offers a convenient once- or twice-daily dosing regimen, which can improve adherence to treatment. Thirdly, it has a relatively low risk of hypoglycemia (low blood sugar) compared to some other diabetes medications, such as sulfonylureas.
  • Furthermore, ZITA DM 20/1000MG may offer additional benefits beyond glycemic control. Some studies suggest that Sitagliptin may have a protective effect on pancreatic beta cells, which are responsible for producing insulin. Metformin, on the other hand, has been associated with modest weight loss in some individuals and may have beneficial effects on cardiovascular risk factors, such as cholesterol levels.
  • ZITA DM 20/1000MG TABLET 15'S is typically prescribed as part of a comprehensive diabetes management plan that includes lifestyle modifications, such as diet and exercise. It is important to take this medication as directed by your healthcare provider and to monitor blood sugar levels regularly. Regular check-ups with your doctor are also essential to assess your response to treatment and to adjust your medication regimen as needed.
  • In summary, ZITA DM 20/1000MG TABLET 15'S offers a comprehensive approach to managing type 2 diabetes by combining the complementary actions of Sitagliptin and Metformin. It effectively lowers blood sugar levels, has a low risk of hypoglycemia, and may offer additional benefits beyond glycemic control. When used in conjunction with lifestyle modifications and under the guidance of a healthcare professional, ZITA DM 20/1000MG can help individuals with type 2 diabetes achieve and maintain optimal glycemic control and improve their overall health and well-being.

How to use ZITA DM 20/1000MG TABLET 15'SArrow

  • ZITA DM 20/1000MG TABLET 15'S is an oral antidiabetic medication used to manage type 2 diabetes mellitus. It combines two active ingredients: sitagliptin (a DPP-4 inhibitor) and metformin (a biguanide). To ensure optimal effectiveness and minimize potential side effects, it is crucial to adhere to the prescribed dosage and administration guidelines provided by your healthcare professional.
  • The usual starting dose depends on your existing treatment regimen and individual needs. Your doctor will determine the appropriate dosage for you. ZITA DM should be taken orally, typically once or twice daily, as directed by your physician. It's generally recommended to take it with meals to help reduce gastrointestinal discomfort associated with metformin.
  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this can affect the way the medication is released into your system. Consistency is key. Try to take ZITA DM at the same time(s) each day to maintain a steady level of medication in your bloodstream. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
  • While taking ZITA DM, it is important to follow a healthy diet and exercise regularly as advised by your doctor or a registered dietitian. This will help improve your blood sugar control and overall health. Monitor your blood sugar levels regularly as directed by your healthcare provider. This will help you and your doctor track how well the medication is working and make any necessary adjustments to your treatment plan.
  • Inform your doctor about all other medications, supplements, and herbal products you are taking, as they may interact with ZITA DM. Pay attention to any potential side effects and report them to your doctor promptly. Common side effects may include nausea, vomiting, diarrhea, stomach upset, and headache. More serious side effects are rare but can occur, such as lactic acidosis (a buildup of lactic acid in the blood).
  • Regular check-ups with your doctor are essential to monitor your kidney function and overall health while taking ZITA DM. It's also vital to stay well-hydrated by drinking plenty of water throughout the day. If you have any questions or concerns about taking ZITA DM, do not hesitate to consult your doctor or pharmacist for clarification.

Quick Tips for ZITA DM 20/1000MG TABLET 15'SArrow

  • Take ZITA DM 20/1000MG TABLET 15'S exactly as prescribed by your doctor. Do not change the dosage or stop taking the medication without consulting your physician. Consistency is key for optimal blood sugar control.
  • ZITA DM 20/1000MG TABLET 15'S is best taken with food to minimize the risk of stomach upset. Taking it at the same time each day will also help you remember to take it regularly and maximize its effectiveness. Incorporate it seamlessly into your meal routine.
  • Regularly monitor your blood sugar levels as directed by your healthcare provider. This will help you understand how ZITA DM 20/1000MG TABLET 15'S is working for you and allow your doctor to make any necessary adjustments to your treatment plan. Keep a log of your readings for better tracking.
  • Maintain a healthy lifestyle by following a balanced diet and exercising regularly. These lifestyle changes, combined with ZITA DM 20/1000MG TABLET 15'S, can significantly improve your blood sugar control and overall health. Consult with a dietitian or certified trainer for personalized guidance.
  • Be aware of the symptoms of low blood sugar (hypoglycemia), such as sweating, shaking, dizziness, and confusion. If you experience these symptoms, consume a fast-acting source of sugar, like juice or glucose tablets, and inform your doctor immediately. Carry a snack for emergencies.
  • Inform your doctor about all other medications, supplements, and herbal products you are taking. Some medications can interact with ZITA DM 20/1000MG TABLET 15'S, potentially affecting its effectiveness or increasing the risk of side effects. A complete medication list is essential for safe and effective treatment.
  • Stay hydrated by drinking plenty of water throughout the day. Proper hydration supports overall health and can help regulate blood sugar levels. Water is a better choice than sugary drinks, which can negatively impact your blood sugar.
  • Attend all scheduled appointments with your doctor and other healthcare providers. Regular check-ups are important for monitoring your progress, managing any side effects, and ensuring that your treatment plan is optimized for your individual needs. Don't skip these appointments!
  • Store ZITA DM 20/1000MG TABLET 15'S at room temperature, away from moisture and direct sunlight. Proper storage helps maintain the medication's effectiveness. Keep it out of reach of children and pets.
  • If you experience any persistent or bothersome side effects, such as nausea, diarrhea, or headache, contact your doctor. They can provide guidance on managing these side effects or adjust your medication if necessary. Don't hesitate to seek medical advice.

Food Interactions with ZITA DM 20/1000MG TABLET 15'SArrow

  • ZITA DM 20/1000MG TABLET 15'S can be taken with or without food. However, it is generally recommended to take it with food, especially with your first main meal of the day, to reduce the risk of stomach upset or gastrointestinal side effects. Consistent timing with meals can also help maintain stable blood sugar levels.

FAQs

What is ZITA DM 20/1000MG TABLET 15'S?Arrow

ZITA DM 20/1000MG TABLET 15'S is a combination of two medicines: Sitagliptin and Metformin. It is used to control high blood sugar levels in people with type 2 diabetes mellitus.

How to use ZITA DM 20/1000MG TABLET 15'S?Arrow

Take ZITA DM 20/1000MG TABLET 15'S in the dose and duration as advised by your doctor. It is better to take it with food.

What are the common side effects of ZITA DM 20/1000MG TABLET 15'S?Arrow

Common side effects of ZITA DM 20/1000MG TABLET 15'S include nausea, vomiting, diarrhea, stomach pain, and loss of appetite.

Is ZITA DM 20/1000MG TABLET 15'S safe for the kidneys?Arrow

ZITA DM 20/1000MG TABLET 15'S should be used with caution in patients with kidney disease. Dose adjustment may be needed. Please consult your doctor.

Is ZITA DM 20/1000MG TABLET 15'S safe during pregnancy?Arrow

There is limited information available on the safety of ZITA DM 20/1000MG TABLET 15'S during pregnancy. It should only be used if clearly needed and advised by your doctor.

How to store ZITA DM 20/1000MG TABLET 15'S?Arrow

Store ZITA DM 20/1000MG TABLET 15'S at room temperature, away from direct sunlight and heat. Keep it out of reach of children and pets.

What happens if I miss a dose of ZITA DM 20/1000MG TABLET 15'S?Arrow

If you miss a dose of ZITA DM 20/1000MG TABLET 15'S, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose.

What are the symptoms of overdose of ZITA DM 20/1000MG TABLET 15'S?Arrow

Symptoms of an overdose of ZITA DM 20/1000MG TABLET 15'S may include nausea, vomiting, abdominal pain, diarrhea, and in severe cases, lactic acidosis.

Does ZITA DM 20/1000MG TABLET 15'S cause weight gain?Arrow

ZITA DM 20/1000MG TABLET 15'S does not usually cause weight gain. However, some patients may experience a slight increase in weight.

What medications should not be taken with ZITA DM 20/1000MG TABLET 15'S?Arrow

ZITA DM 20/1000MG TABLET 15'S can interact with certain medications, such as insulin, sulfonylureas, and certain blood pressure medications. Tell your doctor about all the medications you are taking.

Can ZITA DM 20/1000MG TABLET 15'S cause stomach upset?Arrow

Yes, ZITA DM 20/1000MG TABLET 15'S can cause stomach upset, especially when taken on an empty stomach. Taking it with food can help minimize this side effect.

ZITA DM 20/1000MG TABLET 15'S vs Metformin: What is the difference?Arrow

ZITA DM 20/1000MG TABLET 15'S is a combination of sitagliptin and metformin, while metformin is only metformin. ZITA DM 20/1000MG TABLET 15'S works through two different mechanisms to control blood sugar levels.

Can I drink alcohol while taking ZITA DM 20/1000MG TABLET 15'S?Arrow

It is not recommended to consume alcohol while taking ZITA DM 20/1000MG TABLET 15'S, as it may increase the risk of lactic acidosis.

What are the other brands of Sitagliptin?Arrow

Other brands of Sitagliptin include Januvia, Xemet, and Stigliptin.

What are the other brands of Metformin?Arrow

Other brands of Metformin include Glucophage, Glumetza, and Fortamet.

References

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DrugBank: Sitagliptin. This entry provides comprehensive chemical, pharmacological, and pharmaceutical information on Sitagliptin.

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FDA Label for Janumet (Sitagliptin and Metformin Hydrochloride). This document provides prescribing information, including clinical pharmacology, indications, dosage, and safety information for a combination drug containing sitagliptin and metformin.

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National Center for Biotechnology Information (NCBI): Efficacy and safety of sitagliptin/metformin fixed-dose combination therapy compared to glimepiride/metformin in Korean patients with type 2 diabetes mellitus: A 24-week, multicenter, randomized, open-label, phase IV study. Provides research comparing sitagliptin/metformin to other diabetes treatments.

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National Center for Biotechnology Information (NCBI): Sitagliptin/metformin fixed-dose combination: a practical guide for appropriate patient selection and optimized management. Provides a guide for patient selection and management using sitagliptin/metformin.

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European Medicines Agency (EMA): Januvia. This provides the European regulatory perspective on sitagliptin.

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FDA: Januvia (sitagliptin) tablets prescribing information. Provides comprehensive prescribing information for sitagliptin.

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FDA: Glucophage (metformin hydrochloride) tablets prescribing information. Provides prescribing information for metformin hydrochloride.

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National Center for Biotechnology Information (NCBI): Metformin. This provides a detailed overview of metformin's mechanism of action, pharmacokinetics, and clinical uses.

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