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ZOSTUM 3 GM INJECTION

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ZOSTUM 3 GM INJECTION

By ZUVENTUS HEALTHCARE LIMITED

MRP

937.05

₹400

57.31 % OFF

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Product DetailsArrow

About ZOSTUM 3 GM INJECTION

  • ZOSTUM 3 GM INJECTION is a powerful antibiotic formulation combining Piperacillin and Tazobactam, designed to combat a wide array of bacterial infections. Piperacillin, a broad-spectrum penicillin antibiotic, works by interfering with the bacteria's ability to form cell walls, leading to their destruction. Tazobactam, a beta-lactamase inhibitor, enhances Piperacillin's effectiveness by preventing bacteria from inactivating it. This synergistic combination ensures robust activity against resistant bacterial strains.
  • This injectable medication is particularly effective against severe infections such as pneumonia, intra-abdominal infections, skin and soft tissue infections, and gynecological infections. It is administered intravenously by healthcare professionals in a clinical setting to ensure appropriate dosage and monitoring. ZOSTUM 3 GM INJECTION is often prescribed when other antibiotics have failed to provide relief, making it a crucial tool in managing complex and life-threatening infections.
  • The inclusion of Tazobactam is vital because many bacteria produce enzymes called beta-lactamases that can break down and neutralize antibiotics like Piperacillin. By inhibiting these enzymes, Tazobactam allows Piperacillin to reach its target and effectively kill the bacteria. This makes ZOSTUM 3 GM INJECTION a reliable choice for infections caused by bacteria known to produce beta-lactamases.
  • ZOSTUM 3 GM INJECTION stands as a testament to modern antibiotic therapy, offering a potent solution for combating bacterial infections that pose a significant threat to health. Its dual-action mechanism, combining a powerful antibiotic with a beta-lactamase inhibitor, ensures a comprehensive approach to bacterial eradication and helps improve patient outcomes in severe infection scenarios. As with all antibiotics, ZOSTUM 3 GM INJECTION should be used judiciously and under the guidance of a healthcare professional to minimize the risk of antibiotic resistance.

Uses of ZOSTUM 3 GM INJECTION

  • Treatment of Pneumonia
  • Treatment of Skin and Soft Tissue Infections
  • Treatment of Urinary Tract Infections
  • Treatment of Bone and Joint Infections
  • Treatment of Septicemia (Blood Infection)
  • Treatment of Gynecological Infections
  • Treatment of Intra-abdominal Infections
  • Treatment of Meningitis
  • Surgical Prophylaxis
  • Treatment of Lower Respiratory Tract Infections such as Pneumonia
  • Treatment of Pelvic Inflammatory Disease (PID)
  • Prevention of Postoperative Infections
  • Empirical Treatment of Infections in Neutropenic Patients

How ZOSTUM 3 GM INJECTION Works

  • ZOSTUM 3 GM INJECTION is a powerful antibiotic combination medication containing Cefoperazone and Sulbactam. Cefoperazone is a cephalosporin antibiotic that inhibits bacterial cell wall synthesis. Bacteria need to build cell walls to survive; Cefoperazone blocks this process, leading to bacterial cell death.
  • Specifically, Cefoperazone binds to penicillin-binding proteins (PBPs), which are enzymes essential for the construction of the bacterial cell wall. By blocking PBPs, Cefoperazone prevents the cross-linking of peptidoglycans, the main structural component of the cell wall. This weakens the cell wall, causing it to break down and resulting in the death of the bacteria.
  • Sulbactam, on the other hand, is a beta-lactamase inhibitor. Beta-lactamases are enzymes produced by some bacteria that can inactivate beta-lactam antibiotics like Cefoperazone. Sulbactam binds to these beta-lactamase enzymes, preventing them from breaking down Cefoperazone. This ensures that Cefoperazone can effectively reach its target and kill the bacteria.
  • The combination of Cefoperazone and Sulbactam in ZOSTUM 3 GM INJECTION works synergistically to broaden the spectrum of activity and overcome antibiotic resistance. Sulbactam enhances the effectiveness of Cefoperazone against bacteria that produce beta-lactamases, making the combination more effective against a wider range of infections.
  • Essentially, Cefoperazone directly attacks the bacteria's ability to build its cell wall, while Sulbactam protects Cefoperazone from being destroyed by bacterial enzymes. This dual action makes ZOSTUM 3 GM INJECTION a potent treatment for various bacterial infections.

Side Effects of ZOSTUM 3 GM INJECTIONArrow

Common side effects of ZOSTUM 3 GM INJECTION may include: * Pain, swelling, or redness at the injection site * Diarrhea * Nausea * Vomiting * Rash * Itching Uncommon side effects may include: * Fever * Headache * Dizziness * Abdominal pain * Yeast infection (oral or vaginal) * Allergic reactions (such as hives, difficulty breathing, or swelling of the face, lips, tongue, or throat) * Changes in liver function tests * Blood disorders (such as decreased white blood cells or platelets) * Seizures (rare)

Safety Advice for ZOSTUM 3 GM INJECTIONArrow

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Allergies

Allergies

Tell your doctor if you are allergic to ZOSTUM 3 GM INJECTION or any other medicines.

Dosage of ZOSTUM 3 GM INJECTIONArrow

  • The dosage of ZOSTUM 3 GM INJECTION is determined by several factors, including the severity and type of infection, the patient's age, weight, kidney function, and overall clinical condition. It is crucial to adhere strictly to the prescribed dosage and administration schedule provided by your healthcare professional. Do not self-adjust the dosage or discontinue treatment without consulting your doctor, even if you start feeling better.
  • For adults with mild to moderate infections, the typical dosage ranges from 1 to 2 grams administered intravenously every 8 to 12 hours. In cases of severe infections, the dosage may be increased to 2 to 3 grams every 6 to 8 hours. The duration of treatment varies depending on the infection's nature and the patient's response to therapy, but it generally lasts for 7 to 14 days.
  • In patients with impaired kidney function, dosage adjustments are necessary to prevent drug accumulation and potential toxicity. Your doctor will carefully assess your kidney function and modify the ZOSTUM 3 GM INJECTION dosage accordingly. It is essential to inform your healthcare provider about any pre-existing kidney conditions or any changes in your kidney function during treatment.
  • For pediatric patients, the dosage is calculated based on their weight. The usual dosage ranges from 50 to 200 mg per kg of body weight per day, divided into multiple doses. The exact dosage and frequency of administration will be determined by your doctor based on the child's specific condition and response to treatment.
  • Take 'ZOSTUM 3 GM INJECTION' only as per the prescription by your physician only

What if I miss my dose of ZOSTUM 3 GM INJECTION?Arrow

  • If you miss a dose of ZOSTUM 3 GM INJECTION, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one. Consult your doctor or pharmacist if you have any concerns.

How to store ZOSTUM 3 GM INJECTION?Arrow

  • Keep ZOSTUM 3GM INJ away from the reach of children and pets.
  • Store ZOSTUM 3GM INJ at room temperature.

Benefits of ZOSTUM 3 GM INJECTIONArrow

  • ZOSTUM 3 GM INJECTION is a powerful combination antibiotic medication primarily used to treat a wide range of bacterial infections. Its effectiveness stems from the synergistic action of its two active ingredients: a broad-spectrum cephalosporin antibiotic and a beta-lactamase inhibitor. This combination allows ZOSTUM to combat bacteria that may have developed resistance to other antibiotics, making it a valuable tool in fighting serious and complex infections.
  • One of the key benefits of ZOSTUM 3 GM INJECTION is its broad spectrum of activity. It is effective against a diverse array of bacteria, including both Gram-positive and Gram-negative organisms. This makes it suitable for treating infections affecting various parts of the body, such as the respiratory tract (e.g., pneumonia, bronchitis), urinary tract (e.g., cystitis, pyelonephritis), skin and soft tissues (e.g., cellulitis, abscesses), and intra-abdominal infections (e.g., peritonitis).
  • ZOSTUM's ability to overcome antibiotic resistance is a significant advantage. The beta-lactamase inhibitor component of the injection works by blocking the action of enzymes produced by some bacteria that can inactivate beta-lactam antibiotics (like the cephalosporin in ZOSTUM). By inhibiting these enzymes, ZOSTUM can effectively kill bacteria that would otherwise be resistant to cephalosporin antibiotics alone.
  • This medication is particularly useful in treating severe infections that require hospitalization. It is often administered intravenously, allowing for rapid and complete absorption into the bloodstream, ensuring that the antibiotic reaches the site of infection quickly and effectively. This makes it ideal for situations where a rapid response is crucial, such as in cases of sepsis or other life-threatening infections.
  • Furthermore, ZOSTUM 3 GM INJECTION can be used as an empirical therapy, meaning it can be started before the specific bacteria causing the infection has been identified. This is particularly important in serious infections where delaying treatment could have severe consequences. Once the causative organism has been identified through laboratory testing, the antibiotic regimen can be adjusted accordingly.
  • Beyond its direct antibacterial effects, ZOSTUM can also contribute to faster recovery times by effectively eliminating the infection and reducing the severity of symptoms. This can lead to a quicker return to normal activities and an improved quality of life for patients. The timely and appropriate use of ZOSTUM 3 GM INJECTION can also help prevent the spread of infection to other parts of the body or to other individuals.
  • ZOSTUM is also beneficial in post-operative settings. It can be administered to prevent infections after surgical procedures, particularly those involving the abdominal area or other sites where the risk of bacterial contamination is high. By preventing post-operative infections, ZOSTUM can help reduce the length of hospital stays and the need for additional treatments.
  • The targeted action of ZOSTUM minimizes damage to beneficial bacteria in the gut, unlike some broad-spectrum antibiotics that can disrupt the normal gut flora, leading to complications like antibiotic-associated diarrhea. While some effect on gut bacteria is possible, the combination formulation aims to maximize efficacy against pathogens while minimizing disruption to the microbiome.
  • Another key advantage of ZOSTUM 3 GM INJECTION is its ease of administration in a hospital setting by healthcare professionals. The intravenous route ensures consistent dosing and bioavailability, leading to predictable therapeutic outcomes. Proper administration and monitoring by healthcare providers can help minimize the risk of adverse effects and optimize the effectiveness of the treatment.
  • In conclusion, ZOSTUM 3 GM INJECTION offers a comprehensive approach to combating a wide range of bacterial infections. Its broad spectrum of activity, ability to overcome antibiotic resistance, rapid intravenous delivery, and potential for use as empirical therapy make it a valuable asset in the treatment of serious infections, contributing to faster recovery times, prevention of complications, and improved patient outcomes.

How to use ZOSTUM 3 GM INJECTIONArrow

  • ZOSTUM 3 GM INJECTION is administered intravenously or intramuscularly by a healthcare professional. It is crucial to adhere strictly to the prescribed dosage and duration of treatment as determined by your doctor. Self-administration of this medication is strongly discouraged.
  • Prior to administration, the ZOSTUM powder needs to be reconstituted with a suitable diluent, such as sterile water for injection or 0.9% sodium chloride solution. The healthcare provider will carefully follow the instructions for reconstitution provided by the manufacturer to ensure the correct concentration and prevent any potential compatibility issues.
  • The reconstituted solution should be visually inspected for particulate matter and discoloration before administration. Do not use if the solution is cloudy or contains visible particles.
  • The injection is typically administered slowly, either as a bolus injection over 3-5 minutes or as an intravenous infusion over 20-30 minutes, depending on the specific situation and the doctor's instructions. The healthcare provider will monitor the patient closely during and after the injection for any signs of adverse reactions.
  • It's important to inform your doctor about any existing medical conditions, allergies, or medications you are currently taking before receiving ZOSTUM. This information helps the healthcare provider to make informed decisions about your treatment.
  • If you experience any side effects during or after the injection, such as rash, itching, swelling, difficulty breathing, or dizziness, inform your healthcare provider immediately.
  • To maximize the effectiveness of ZOSTUM, it is important to complete the full course of treatment, even if you start feeling better before the prescribed duration. Discontinuing the medication prematurely may lead to recurrence of the infection or development of antibiotic resistance.
  • ZOSTUM should be stored according to the manufacturer's instructions, typically in a cool, dry place away from direct sunlight and moisture. Keep out of reach of children. Any unused portion of the reconstituted solution should be discarded properly as per healthcare guidelines.

Quick Tips for ZOSTUM 3 GM INJECTIONArrow

  • **Complete the Full Course:** Even if you start feeling better before you finish the ZOSTUM 3 GM INJECTION treatment, it's crucial to complete the entire course as prescribed by your doctor. Stopping early can allow the infection to persist and potentially lead to antibiotic resistance, making future infections harder to treat.
  • **Stay Hydrated:** When on ZOSTUM 3 GM INJECTION, drink plenty of fluids like water, clear broths, or herbal teas. Staying hydrated helps your body flush out the medication and any toxins released by the infection, aiding in a faster recovery and minimizing potential side effects.
  • **Inform Your Doctor About Allergies:** Before starting ZOSTUM 3 GM INJECTION, tell your doctor about any allergies you have, especially to penicillin or cephalosporin antibiotics. Allergic reactions can be serious, and your doctor needs this information to ensure your safety and choose the most appropriate treatment.
  • **Report Side Effects Promptly:** While ZOSTUM 3 GM INJECTION is generally well-tolerated, some people may experience side effects like diarrhea, nausea, or skin rash. If you experience any unusual or bothersome symptoms, report them to your doctor right away. They can provide guidance on how to manage the side effects or adjust your treatment plan if necessary.
  • **Follow Storage Instructions:** Ensure proper storage of ZOSTUM 3 GM INJECTION. Usually, this medication is administered in a hospital setting and prepared by a healthcare professional. However, if you are continuing treatment at home, follow your doctor's or pharmacist's instructions carefully for preparation and storage to maintain its effectiveness and safety.

Food Interactions with ZOSTUM 3 GM INJECTIONArrow

  • ZOSTUM 3 GM INJECTION does not typically interact with food. It can be administered without regard to meals. However, it's essential to follow your doctor's instructions regarding the timing and method of administration.

FAQs

What is ZOSTUM 3 GM Injection used for?Arrow

ZOSTUM 3 GM Injection is used to treat bacterial infections, such as pneumonia, skin infections, abdominal infections, gynecological infections, and urinary tract infections.

How is ZOSTUM 3 GM Injection administered?Arrow

ZOSTUM 3 GM Injection is usually administered by a healthcare professional via injection into a vein (intravenously) or muscle (intramuscularly).

What are the common side effects of ZOSTUM 3 GM Injection?Arrow

Common side effects of ZOSTUM 3 GM Injection include pain, swelling, redness at the injection site, diarrhea, nausea, and vomiting.

Is ZOSTUM 3 GM Injection safe for pregnant women?Arrow

Limited data is available on the use of ZOSTUM 3 GM Injection during pregnancy. Therefore, it should only be used when clearly needed and prescribed by a doctor.

Is ZOSTUM 3 GM Injection safe for breastfeeding women?Arrow

ZOSTUM 3 GM Injection may be excreted in breast milk. Therefore, breastfeeding women should consult their doctor before using it.

Does ZOSTUM 3 GM Injection interact with other medications?Arrow

ZOSTUM 3 GM Injection may interact with certain medications, such as aminoglycoside antibiotics and probenecid. Therefore, it is important to tell your doctor about all the medications you are taking.

How should ZOSTUM 3 GM Injection be stored?Arrow

ZOSTUM 3 GM Injection should be stored at room temperature, away from direct sunlight and heat. Keep it out of reach of children.

What happens if I miss a dose of ZOSTUM 3 GM Injection?Arrow

If you miss a dose of ZOSTUM 3 GM Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Can ZOSTUM 3 GM Injection cause allergic reactions?Arrow

ZOSTUM 3 GM Injection can cause allergic reactions in some people. If you experience symptoms of an allergic reaction, such as rash, itching, swelling, or difficulty breathing, seek immediate medical attention.

Is ZOSTUM 3 GM Injection safe for people with kidney problems?Arrow

People with kidney problems should use ZOSTUM 3 GM Injection with caution. The dosage may need to be adjusted according to kidney function. Consult your doctor.

Can ZOSTUM 3 GM Injection cause dizziness?Arrow

ZOSTUM 3 GM Injection may cause dizziness in some people. Avoid driving or operating machinery if you experience dizziness.

What are the symptoms of an overdose of ZOSTUM 3 GM Injection?Arrow

Symptoms of an overdose of ZOSTUM 3 GM Injection may include nausea, vomiting, diarrhea, dizziness, confusion, and seizures. If you suspect you have taken an overdose of ZOSTUM 3 GM Injection, seek immediate medical attention.

What are the alternatives to ZOSTUM 3 GM Injection?Arrow

Alternatives to ZOSTUM 3 GM Injection include other antibiotics that can treat similar types of infections. Your doctor will determine the best alternative for you.

What is the main ingredient of ZOSTUM 3 GM Injection?Arrow

The main ingredient of ZOSTUM 3 GM Injection is Ceftriaxone, which is an antibiotic.

Can ZOSTUM 3 GM Injection be used to treat viral infections?Arrow

No, ZOSTUM 3 GM Injection is an antibiotic and is only effective for treating bacterial infections. It is not effective against viral infections.

References

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Rocephin (ceftriaxone sodium) prescribing information. This FDA document provides detailed information on ceftriaxone, including its chemical structure, mechanism of action, indications, dosage, and adverse effects.

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DrugBank entry for Ceftriaxone. This page offers comprehensive details on ceftriaxone, encompassing its chemical properties, pharmacology, and therapeutic applications.

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Pharmacokinetics and pharmacodynamics of ceftriaxone in different clinical conditions: a review. This article reviews the pharmacokinetic and pharmacodynamic properties of ceftriaxone in various patient populations.

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Ceftriaxone. This StatPearls entry summarizes the uses, administration, and potential adverse effects of ceftriaxone.

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Micromedex. A comprehensive drug information database providing in-depth information on Zostum's ingredients, including ceftriaxone.

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UpToDate. A clinical resource that provides detailed information on ceftriaxone's uses, dosage, and potential side effects.

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Very good and quik responce for all medicines

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Reviewed on 03-01-2023

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(5/5)


Marketer / Manufacturer Details

ZUVENTUS HEALTHCARE LIMITED

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India

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ZOSTUM 3 GM INJECTION

MRP

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₹400

57.31 % OFF

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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