ZYROVA F 10MG TABLET 10'S
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ZYROVA F 10MG TABLET 10'S
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ZYROVA F 10MG TABLET 10'S

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ZYROVA F 10MG TABLET 10'S

By ZYDUS LIFESCIENCES LIMITED

MRP

350.9

₹298.26

15 % OFF

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About ZYROVA F 10MG TABLET 10'S

  • ZYROVA F 10MG TABLET 10'S is a combination medication designed to manage cholesterol levels and reduce the risk of cardiovascular events. It contains two active ingredients: Rosuvastatin and Fenofibrate. Rosuvastatin belongs to a class of drugs called statins, which work by inhibiting an enzyme called HMG-CoA reductase. This enzyme is crucial in the production of cholesterol in the liver. By blocking this enzyme, rosuvastatin lowers the amount of cholesterol produced, particularly LDL-cholesterol (the 'bad' cholesterol) which contributes to plaque buildup in arteries.
  • Fenofibrate, on the other hand, belongs to a class of drugs called fibrates. Fenofibrate primarily works by increasing the breakdown of triglycerides, another type of fat in the blood. It also helps to increase the levels of HDL-cholesterol (the 'good' cholesterol), which helps remove LDL-cholesterol from the arteries. The combined action of rosuvastatin and fenofibrate provides a comprehensive approach to managing lipid profiles, addressing both high cholesterol and high triglyceride levels.
  • ZYROVA F 10MG TABLET is typically prescribed for individuals who have not achieved adequate control of their cholesterol and triglyceride levels with diet and exercise alone. It's important to take this medication as directed by your healthcare provider. Regular monitoring of liver function and lipid levels is recommended while taking ZYROVA F 10MG TABLET. Patients should also be aware of potential side effects and promptly report any unusual symptoms to their doctor. This medication is a valuable tool in preventing heart disease and stroke when used as part of a comprehensive treatment plan.

Uses of ZYROVA F 10MG TABLET 10'S

  • Treatment of high cholesterol
  • Treatment of mixed dyslipidemia
  • Prevention of heart disease
  • Prevention of stroke
  • Prevention of myocardial infarction

How ZYROVA F 10MG TABLET 10'S Works

  • ZYROVA F 10MG TABLET is a combination medication containing Fenofibrate and Rosuvastatin. It is primarily used to manage abnormal cholesterol levels and reduce the risk of cardiovascular diseases. To understand how ZYROVA F 10MG TABLET works, it’s essential to look at the individual roles of its active ingredients: Fenofibrate and Rosuvastatin.
  • **Rosuvastatin:** Rosuvastatin belongs to a class of drugs known as statins or HMG-CoA reductase inhibitors. It primarily targets the liver to reduce cholesterol production. Here’s how it works: * **Inhibits HMG-CoA Reductase:** Rosuvastatin blocks the action of HMG-CoA reductase, an enzyme crucial for producing cholesterol in the liver. By inhibiting this enzyme, the liver produces less cholesterol. * **Increases LDL Receptors:** As the liver produces less cholesterol, it compensates by increasing the number of LDL (low-density lipoprotein) receptors on its surface. These receptors bind to LDL cholesterol circulating in the bloodstream, effectively removing it from the blood. LDL cholesterol is often referred to as 'bad' cholesterol because high levels can lead to plaque formation in arteries.
  • **Fenofibrate:** Fenofibrate is a fibric acid derivative that primarily works to lower triglyceride levels and, to a lesser extent, increase HDL (high-density lipoprotein) cholesterol, often called 'good' cholesterol. Here’s how it works: * **Activates PPARα:** Fenofibrate activates a protein called peroxisome proliferator-activated receptor alpha (PPARα). PPARα is found in various tissues, including the liver and muscle. * **Increases Lipoprotein Lipase (LPL):** Activation of PPARα leads to increased production of lipoprotein lipase (LPL), an enzyme that breaks down triglycerides in the blood. This results in lower triglyceride levels. * **Reduces VLDL Production:** Fenofibrate also reduces the production of very-low-density lipoprotein (VLDL) in the liver. VLDL is another type of lipoprotein that carries triglycerides in the blood. * **Increases HDL Cholesterol:** Additionally, fenofibrate can increase the levels of HDL cholesterol by increasing the production of apolipoproteins A-I and A-II, which are components of HDL particles.
  • **Combined Action:** When taken together in ZYROVA F 10MG TABLET, Rosuvastatin and Fenofibrate provide a complementary effect on lipid levels. Rosuvastatin primarily lowers LDL cholesterol, while Fenofibrate primarily lowers triglycerides and raises HDL cholesterol. This combination is particularly useful for patients who have mixed dyslipidemia, characterized by high LDL cholesterol, high triglycerides, and low HDL cholesterol. By addressing multiple aspects of lipid metabolism, ZYROVA F 10MG TABLET helps reduce the risk of atherosclerosis (plaque buildup in arteries), heart attack, stroke, and other cardiovascular complications. It is typically used in conjunction with lifestyle modifications such as diet and exercise to achieve optimal results. Always follow your doctor's instructions when taking this medication.

Side Effects of ZYROVA F 10MG TABLET 10'SArrow

Common side effects of ZYROVA F 10MG TABLET may include headache, muscle pain or weakness, nausea, diarrhea, constipation, upset stomach, gas, dizziness, and fatigue. Less common but potentially serious side effects include liver problems (such as jaundice, dark urine, or persistent fatigue), muscle damage (rhabdomyolysis, indicated by severe muscle pain and weakness), increased blood sugar levels, and allergic reactions (rash, itching, swelling). Other possible side effects are memory loss, confusion, and depression. Consult your doctor immediately if you experience any severe or persistent side effects.

Safety Advice for ZYROVA F 10MG TABLET 10'SArrow

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Allergies

Allergies

Do not use ZYROVA F 10MG TABLET 10'S if you are allergic to it.

Dosage of ZYROVA F 10MG TABLET 10'SArrow

  • The recommended dosage of ZYROVA F 10MG TABLET 10'S varies depending on individual patient needs and should be determined by a healthcare professional. Typically, the starting dose is 10mg once daily, which may be adjusted based on the patient's response and tolerance. The maximum recommended dose is usually 80mg per day. It's crucial to adhere to the prescribed dosage and schedule, as exceeding the recommended amount can increase the risk of adverse effects without necessarily providing additional therapeutic benefits.
  • ZYROVA F 10MG TABLET 10'S is usually taken orally, with or without food. Consistency in timing each day is recommended to maintain stable blood levels of the medication. If a dose is missed, it should be taken as soon as remembered, unless it is almost time for the next scheduled dose. In that case, the missed dose should be skipped, and the regular dosing schedule should be resumed. Doubling up on doses to compensate for missed ones is not advisable.
  • Patients should continue taking ZYROVA F 10MG TABLET 10'S even if they feel well, as the medication helps manage cholesterol levels and reduce the risk of cardiovascular events over the long term. Discontinuation of the medication without consulting a healthcare provider could lead to a rebound effect in cholesterol levels and potentially increase cardiovascular risk. Regular monitoring of cholesterol levels and liver function is important while taking this medication.
  • Certain factors, such as age, kidney function, and other medical conditions, may influence the appropriate dosage of ZYROVA F 10MG TABLET 10'S. Patients with kidney problems may require lower doses. Elderly patients may also be more susceptible to the effects of the medication and may need dosage adjustments. Always inform your physician about all other medications you are taking, as drug interactions can also affect the dosage requirements.
  • Take 'ZYROVA F 10MG TABLET 10'S' only as per the prescription by your physician only

What if I miss my dose of ZYROVA F 10MG TABLET 10'S?Arrow

  • If you miss a dose of ZYROVA F 10MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store ZYROVA F 10MG TABLET 10'S?Arrow

  • Keep ZYROVA F 10MG TAB 1X10 away from the reach of children and pets.
  • Store ZYROVA F 10MG TAB 1X10 at room temperature.

Benefits of ZYROVA F 10MG TABLET 10'SArrow

  • ZYROVA F 10MG TABLET 10'S offers a dual-action approach to managing cholesterol levels and reducing the risk of cardiovascular events. This combination medication contains both a statin (rosuvastatin) and a fibrate (fenofibrate), providing comprehensive lipid management.
  • Rosuvastatin, the statin component, primarily works by inhibiting the enzyme HMG-CoA reductase in the liver. This enzyme is crucial for cholesterol production. By blocking this enzyme, rosuvastatin effectively lowers the levels of LDL-cholesterol (bad cholesterol) in the bloodstream. Lowering LDL-cholesterol is vital in preventing the buildup of plaque in the arteries, a process known as atherosclerosis.
  • Fenofibrate, the fibrate component, primarily works by activating peroxisome proliferator-activated receptor alpha (PPARα). This activation leads to increased breakdown of triglycerides and increased production of HDL-cholesterol (good cholesterol). Lowering triglycerides and raising HDL-cholesterol are important for improving overall lipid profiles and reducing cardiovascular risk.
  • ZYROVA F 10MG TABLET 10'S is particularly beneficial for individuals with mixed dyslipidemia, a condition characterized by elevated levels of LDL-cholesterol, triglycerides, and low levels of HDL-cholesterol. By addressing all three components of dyslipidemia, this medication offers a more comprehensive approach to lipid management compared to statins alone.
  • The combined action of rosuvastatin and fenofibrate in ZYROVA F 10MG TABLET 10'S helps to reduce the risk of heart attacks, strokes, and other cardiovascular complications. By lowering LDL-cholesterol, raising HDL-cholesterol, and reducing triglycerides, this medication helps to prevent the formation of plaques in the arteries and improve blood flow.
  • ZYROVA F 10MG TABLET 10'S can also improve endothelial function, which is the ability of the blood vessels to relax and contract properly. Improved endothelial function is crucial for maintaining healthy blood pressure and preventing cardiovascular disease.
  • ZYROVA F 10MG TABLET 10'S offers a convenient once-daily oral administration, making it easier for patients to adhere to their treatment regimen. Consistency in taking the medication is essential for achieving optimal results.
  • This medication is often prescribed when lifestyle modifications, such as diet and exercise, are not sufficient to achieve desired lipid levels. It serves as an adjunct to lifestyle changes, providing a more powerful tool for managing cholesterol and triglycerides.
  • ZYROVA F 10MG TABLET 10'S should be used under the guidance of a healthcare professional. Regular monitoring of lipid levels and liver function is necessary to ensure the medication's effectiveness and safety. Dosage adjustments may be needed based on individual response and tolerance.
  • ZYROVA F 10MG TABLET 10'S contributes to slowing down the progression of atherosclerotic plaques, reducing the likelihood of arterial blockages and subsequent cardiovascular events.
  • Patients with diabetes or metabolic syndrome, who often have complex lipid abnormalities, may find ZYROVA F 10MG TABLET 10'S particularly useful due to its ability to address multiple lipid parameters simultaneously.

How to use ZYROVA F 10MG TABLET 10'SArrow

  • ZYROVA F 10MG TABLET 10'S is a combination medication containing Fenofibrate and Rosuvastatin, primarily used to lower cholesterol and triglyceride levels in the blood while reducing the risk of cardiovascular diseases. It's crucial to follow your doctor's instructions precisely when taking this medication. Generally, ZYROVA F 10MG TABLET 10'S is taken orally once daily, with or without food, but it's best to take it at the same time each day to maintain consistent blood levels.
  • Swallow the tablet whole with a glass of water; do not crush, chew, or break it, as this can affect how the medication is released and absorbed. The dosage is determined by your doctor based on your medical condition, response to treatment, and other medications you may be taking. Do not change the dosage or stop taking ZYROVA F 10MG TABLET 10'S without consulting your doctor, as this could lead to a rebound effect or worsening of your condition.
  • It's important to maintain a healthy diet and exercise regularly while taking ZYROVA F 10MG TABLET 10'S to maximize its effectiveness. Your doctor may recommend specific dietary changes and an exercise plan. Regular blood tests are necessary to monitor your cholesterol and triglyceride levels, as well as to check for any potential side effects. Be sure to attend all scheduled appointments with your doctor and report any unusual symptoms or side effects you experience while taking this medication.
  • If you miss a dose of ZYROVA F 10MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up. Store ZYROVA F 10MG TABLET 10'S at room temperature, away from moisture and heat. Keep it out of the reach of children and pets. Always consult your healthcare provider for personalized medical advice and guidance.

Quick Tips for ZYROVA F 10MG TABLET 10'SArrow

  • **Take Zyrova F 10mg Tablet as prescribed by your doctor.** It's crucial to adhere to the prescribed dosage and schedule for optimal results. Do not alter the dosage or stop taking the medication without consulting your healthcare provider, even if you feel better. Consistent use is key to managing your cholesterol and triglyceride levels effectively. Remember, this medication is meant to be used in conjunction with lifestyle changes.
  • **Combine Zyrova F 10mg Tablet with a heart-healthy lifestyle.** Medication alone is not enough. Incorporate regular physical activity, such as brisk walking, jogging, or swimming, for at least 30 minutes most days of the week. Adopt a diet low in saturated and trans fats, cholesterol, and processed foods. Increase your intake of fruits, vegetables, and whole grains. Quitting smoking and managing stress are also vital for cardiovascular health. Zyrova F works best when combined with these lifestyle modifications.
  • **Be aware of potential side effects and report them to your doctor.** While generally well-tolerated, Zyrova F 10mg Tablet can cause side effects in some individuals. Common side effects may include muscle pain or weakness (myalgia), digestive issues (such as nausea, constipation, or diarrhea), and headache. More serious side effects, though rare, can include liver problems or severe muscle damage (rhabdomyolysis). If you experience any unusual or persistent symptoms, especially unexplained muscle pain, tenderness, or weakness, contact your doctor immediately. Regular monitoring of liver function may be recommended.
  • **Inform your doctor about all other medications and supplements you are taking.** Drug interactions can affect how Zyrova F 10mg Tablet works or increase the risk of side effects. Be sure to tell your doctor about all prescription medications, over-the-counter drugs, vitamins, herbal supplements, and any other substances you are taking. This includes medications like fibrates (another type of cholesterol-lowering drug), certain antibiotics, antifungals, and immunosuppressants. Your doctor can assess potential interactions and adjust your treatment plan accordingly. It is also important to mention any pre-existing medical conditions you have.
  • **Monitor your cholesterol and triglyceride levels regularly.** Zyrova F 10mg Tablet helps to lower cholesterol and triglyceride levels, but it's important to track your progress. Your doctor will likely order periodic blood tests to monitor your lipid profile and assess how well the medication is working. These tests will help your doctor determine if any adjustments to your dosage or treatment plan are needed. Regular monitoring ensures that you are achieving your target cholesterol levels and reducing your risk of cardiovascular events. Aim for an LDL cholesterol level below 100 mg/dL, or even lower if you have a high risk of heart disease.

Food Interactions with ZYROVA F 10MG TABLET 10'SArrow

  • ZYROVA F 10MG TABLET 10'S can be taken with or without food. However, it is important to take the medicine at the same time each day to maintain a consistent level of medication in your body. Avoid consuming large amounts of grapefruit juice while taking this medication, as it can increase the level of the drug in your bloodstream and potentially increase the risk of side effects. Consult your doctor or pharmacist for specific dietary advice related to your treatment.

FAQs

What is ZYROVA F 10MG TABLET 10'S used for?Arrow

ZYROVA F 10MG TABLET 10'S is primarily used to lower high cholesterol and triglyceride levels, reducing the risk of heart diseases.

What are the common side effects of ZYROVA F 10MG TABLET 10'S?Arrow

Common side effects include muscle pain, headache, nausea, and fatigue. Consult a doctor if these side effects persist or become severe.

What are the ingredients in ZYROVA F 10MG TABLET 10'S?Arrow

ZYROVA F 10MG TABLET 10'S mainly contains Atorvastatin and Fenofibrate.

Can ZYROVA F 10MG TABLET 10'S be taken with or without food?Arrow

ZYROVA F 10MG TABLET 10'S can be taken with or without food, but it is better to take it at the same time each day.

What should I do if I miss a dose of ZYROVA F 10MG TABLET 10'S?Arrow

If you miss a dose, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue with your regular schedule.

Is ZYROVA F 10MG TABLET 10'S safe for pregnant women?Arrow

ZYROVA F 10MG TABLET 10'S is not safe for pregnant women. It should not be used during pregnancy.

Is ZYROVA F 10MG TABLET 10'S safe for breastfeeding women?Arrow

ZYROVA F 10MG TABLET 10'S is not safe for breastfeeding women. It should not be used during breastfeeding.

Is it safe to consume alcohol with ZYROVA F 10MG TABLET 10'S?Arrow

Consuming alcohol with ZYROVA F 10MG TABLET 10'S is not safe, as it can increase the risk of liver problems.

Is ZYROVA F 10MG TABLET 10'S safe for children?Arrow

ZYROVA F 10MG TABLET 10'S is not recommended for children unless directed by a doctor.

How should ZYROVA F 10MG TABLET 10'S be stored?Arrow

Store ZYROVA F 10MG TABLET 10'S at room temperature, away from direct sunlight and moisture.

Can ZYROVA F 10MG TABLET 10'S interact with other medications?Arrow

ZYROVA F 10MG TABLET 10'S can interact with certain medications, such as anticoagulants and some antifungal drugs. Inform your doctor about all the medications you are taking.

Can ZYROVA F 10MG TABLET 10'S cause weight gain?Arrow

ZYROVA F 10MG TABLET 10'S is not likely to cause weight gain, but consult your doctor if you experience weight gain.

How long does it take for ZYROVA F 10MG TABLET 10'S to work?Arrow

It may take a few weeks for ZYROVA F 10MG TABLET 10'S to lower cholesterol levels.

Can ZYROVA F 10MG TABLET 10'S cause muscle pain?Arrow

Yes, ZYROVA F 10MG TABLET 10'S can cause muscle pain. Contact your doctor immediately if you experience severe muscle pain.

Are there alternatives to ZYROVA F 10MG TABLET 10'S?Arrow

Yes, there are other brands and generic alternatives to Atorvastatin and Fenofibrate available. Consult your doctor to determine which option is best for you.

References

Book Icon

FDA - CRESTOR (rosuvastatin calcium) tablets. Full Prescribing Information. This document contains detailed information about rosuvastatin calcium, including its pharmacology, clinical studies, adverse reactions, and dosage and administration.

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DrugBank - Rosuvastatin. A comprehensive resource providing information on rosuvastatin, including its mechanism of action, pharmacokinetics, drug interactions, and therapeutic uses.

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National Center for Biotechnology Information (NCBI) - Rosuvastatin: A Comprehensive Review of its Pharmacokinetics, Pharmacodynamics and Clinical Profile. This review article discusses the pharmacokinetic and pharmacodynamic properties of rosuvastatin, as well as its clinical efficacy and safety.

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European Medicines Agency (EMA) - CRESTOR. European Public Assessment Report (EPAR) for Crestor, providing a summary of the scientific evaluation of rosuvastatin.

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Electronic Medicines Compendium (EMC) - Crestor 5 mg, 10 mg, 20 mg and 40 mg film-coated tablets. Summary of Product Characteristics.

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Marketer / Manufacturer Details

ZYDUS LIFESCIENCES LIMITED

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