ZYROVA F 5MG TABLET 10'S
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ZYROVA F 5MG TABLET 10'S
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ZYROVA F 5MG TABLET 10'S

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ZYROVA F 5MG TABLET 10'S

By ZYDUS LIFESCIENCES LIMITED

MRP

202.9

₹172.47

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About ZYROVA F 5MG TABLET 10'S

  • ZYROVA F 5MG TABLET 10'S is a combination medication meticulously formulated to address elevated cholesterol levels and associated cardiovascular risks. It combines two active ingredients: Rosuvastatin and Fenofibrate. Rosuvastatin belongs to a class of drugs known as statins, while Fenofibrate is a fibrate.
  • Rosuvastatin functions by inhibiting an enzyme called HMG-CoA reductase, which plays a crucial role in the production of cholesterol in the liver. By blocking this enzyme, Rosuvastatin effectively lowers the levels of LDL-cholesterol (bad cholesterol) in the bloodstream. It also helps to increase HDL-cholesterol (good cholesterol) and reduce triglycerides.
  • Fenofibrate primarily works by activating a protein called PPARα (peroxisome proliferator-activated receptor alpha). This activation leads to increased breakdown and clearance of triglycerides from the blood. Additionally, Fenofibrate can modestly increase HDL-cholesterol levels.
  • The synergistic action of Rosuvastatin and Fenofibrate in ZYROVA F 5MG TABLET 10'S provides a comprehensive approach to managing dyslipidemia, a condition characterized by abnormal lipid levels in the blood. This combination is particularly beneficial for individuals with mixed hyperlipidemia, where both cholesterol and triglyceride levels are elevated.
  • ZYROVA F 5MG TABLET 10'S is typically prescribed as an adjunct to lifestyle modifications, such as diet and exercise. It is crucial to adhere to the prescribed dosage and follow the recommendations of your healthcare provider. Regular monitoring of lipid levels and liver function is recommended during treatment with this medication.
  • This medication is generally well-tolerated; however, potential side effects may include muscle pain, digestive issues, and liver enzyme elevations. It is essential to promptly report any unusual symptoms or concerns to your doctor. ZYROVA F 5MG TABLET 10'S should be used with caution in individuals with pre-existing liver or kidney disease. Always consult your physician or pharmacist for personalized advice.

Uses of ZYROVA F 5MG TABLET 10'S

  • Treatment of High Cholesterol
  • Treatment of Mixed Dyslipidemia
  • Treatment of High Triglycerides
  • Prevention of Heart Attack
  • Prevention of Stroke

How ZYROVA F 5MG TABLET 10'S Works

  • ZYROVA F 5MG TABLET 10'S is a combination medication designed to manage cholesterol levels effectively. It combines two active ingredients: Fenofibrate and Rosuvastatin. Each component works through different mechanisms to achieve a synergistic effect in lowering lipids.
  • Rosuvastatin belongs to a class of drugs called statins, or HMG-CoA reductase inhibitors. It primarily works by blocking the action of HMG-CoA reductase, an enzyme crucial for the synthesis of cholesterol in the liver. By inhibiting this enzyme, rosuvastatin reduces the production of cholesterol within the liver cells. This reduction triggers a compensatory mechanism where liver cells increase the number of LDL receptors on their surface. LDL receptors bind to LDL cholesterol (often called 'bad' cholesterol) in the bloodstream, facilitating its removal from the blood and into the liver for processing. Consequently, rosuvastatin effectively lowers LDL cholesterol levels.
  • Fenofibrate, on the other hand, belongs to a class of medications called fibrates. It primarily works by activating a protein called peroxisome proliferator-activated receptor alpha (PPARα). PPARα is found in various tissues, including the liver and muscles, and plays a crucial role in lipid metabolism. When fenofibrate activates PPARα, it leads to several beneficial effects. Firstly, it increases the breakdown of triglycerides, a type of fat found in the blood. Secondly, it increases the production of high-density lipoprotein (HDL) cholesterol, often referred to as 'good' cholesterol. Finally, it can also reduce the production of apolipoprotein C-III, a protein that inhibits the breakdown of triglycerides. Through these actions, fenofibrate helps to lower triglyceride levels and increase HDL cholesterol levels.
  • The combined action of rosuvastatin and fenofibrate in ZYROVA F 5MG TABLET 10'S addresses multiple aspects of lipid metabolism. Rosuvastatin reduces the production of LDL cholesterol, while fenofibrate enhances triglyceride breakdown and increases HDL cholesterol levels. This dual approach is particularly beneficial for individuals with mixed dyslipidemia, a condition characterized by elevated LDL cholesterol, elevated triglycerides, and low HDL cholesterol. By targeting these different lipid parameters, ZYROVA F 5MG TABLET 10'S helps to reduce the risk of cardiovascular events such as heart attacks and strokes.
  • In summary, ZYROVA F 5MG TABLET 10'S works by utilizing the complementary mechanisms of rosuvastatin and fenofibrate to effectively manage cholesterol levels. Rosuvastatin inhibits cholesterol production in the liver, leading to lower LDL cholesterol, while fenofibrate activates PPARα to reduce triglycerides and increase HDL cholesterol. This combined action provides a comprehensive approach to managing mixed dyslipidemia and reducing cardiovascular risk.

Side Effects of ZYROVA F 5MG TABLET 10'SArrow

Common side effects of ZYROVA F 5MG TABLET may include: Headache, Dizziness, Nausea, Vomiting, Stomach pain, Constipation, Diarrhea, Fatigue, Muscle pain, Joint pain, Back pain, Increased blood sugar levels, Upper respiratory tract infection, Inflammation of nasal passages, Sore throat. Uncommon side effects may include: Allergic reactions (rash, itching, swelling), Liver problems (yellowing of skin or eyes), Kidney problems (changes in urination), Hair loss, Memory problems, Confusion, Depression, Sleep disturbances (insomnia), Erectile dysfunction, Breast enlargement in men, Numbness or tingling in hands or feet, Pancreatitis, Gallbladder problems.

Safety Advice for ZYROVA F 5MG TABLET 10'SArrow

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Allergies

Allergies

Do not use Zyrova F 5mg Tablet if you are allergic to it.

Dosage of ZYROVA F 5MG TABLET 10'SArrow

  • The recommended dosage of 'ZYROVA F 5MG TABLET 10'S' varies depending on individual patient factors, including the severity of their condition, their response to treatment, and any other underlying medical conditions they may have. It is crucial to adhere strictly to the dosage instructions provided by your healthcare provider.
  • Typically, 'ZYROVA F 5MG TABLET 10'S' is administered orally, usually once daily. The tablet should be swallowed whole with a glass of water and can be taken with or without food. However, it's best to take it at the same time each day to maintain consistent levels of the medication in your system.
  • Your physician may start you on a lower dose of 'ZYROVA F 5MG TABLET 10'S' and gradually increase it over time as needed. This allows them to assess your tolerance to the medication and minimize the risk of potential side effects. It is important to not adjust your dosage without consulting your doctor, even if you feel your symptoms are improving or worsening.
  • If you miss a dose of 'ZYROVA F 5MG TABLET 10'S', take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this can increase the risk of adverse effects.
  • It's essential to complete the full course of treatment with 'ZYROVA F 5MG TABLET 10'S' as prescribed by your doctor, even if you start feeling better. Stopping the medication prematurely can lead to a relapse of your condition.
  • Take 'ZYROVA F 5MG TABLET 10'S' only as per the prescription by your physician only

What if I miss my dose of ZYROVA F 5MG TABLET 10'S?Arrow

  • If you miss a dose of ZYROVA F 5MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How to store ZYROVA F 5MG TABLET 10'S?Arrow

  • Keep ZYROVA F 5MG TAB 1X10 away from the reach of children and pets.
  • Store ZYROVA F 5MG TAB 1X10 at room temperature.

Benefits of ZYROVA F 5MG TABLET 10'SArrow

  • ZYROVA F 5MG TABLET 10'S is a combination medication containing fenofibrate and rosuvastatin, designed to address multiple lipid abnormalities simultaneously. This dual-action approach offers several significant benefits for individuals at risk of or suffering from cardiovascular diseases. Primarily, it's used to lower high levels of 'bad' cholesterol (low-density lipoprotein or LDL) and triglycerides while raising levels of 'good' cholesterol (high-density lipoprotein or HDL). By reducing LDL cholesterol, ZYROVA F helps prevent the buildup of plaque in the arteries, a process known as atherosclerosis. This is crucial in reducing the risk of heart attacks, strokes, and other cardiovascular complications.
  • The inclusion of fenofibrate specifically targets high triglyceride levels, another significant risk factor for heart disease and pancreatitis. Fenofibrate works by activating a protein called PPARα, which increases the breakdown and clearance of triglycerides from the bloodstream. Rosuvastatin, on the other hand, is a powerful statin that inhibits the production of cholesterol in the liver. This combined action ensures a more comprehensive approach to managing dyslipidemia compared to using either medication alone.
  • ZYROVA F is particularly beneficial for patients with mixed dyslipidemia, a condition characterized by elevated LDL cholesterol, elevated triglycerides, and low HDL cholesterol. This condition often requires a multi-faceted treatment approach, and ZYROVA F provides a convenient and effective solution by addressing all three lipid abnormalities in a single tablet. The improved lipid profile achieved with ZYROVA F can lead to a reduced risk of cardiovascular events and improved overall cardiovascular health.
  • Beyond its direct effects on lipid levels, ZYROVA F may also offer additional benefits, such as reducing inflammation and improving endothelial function. Inflammation plays a key role in the development of atherosclerosis, and both fenofibrate and rosuvastatin have been shown to have anti-inflammatory properties. Improved endothelial function, which refers to the health of the inner lining of blood vessels, can also contribute to better cardiovascular health. ZYROVA F is typically used in conjunction with lifestyle modifications, such as diet and exercise, to maximize its effectiveness. A heart-healthy diet low in saturated and trans fats, regular physical activity, and maintaining a healthy weight are essential components of a comprehensive treatment plan for dyslipidemia. Furthermore, ZYROVA F can be more convenient for patients who require both a statin and a fibrate, as it reduces the pill burden and simplifies the medication regimen, potentially improving adherence to treatment. As with all medications, ZYROVA F should be taken under the guidance and supervision of a healthcare professional, who can monitor its effectiveness and manage any potential side effects.
  • In summary, ZYROVA F 5MG TABLET 10'S offers a comprehensive approach to managing dyslipidemia by lowering LDL cholesterol and triglycerides while raising HDL cholesterol. This leads to a reduced risk of atherosclerosis, heart attacks, strokes, and pancreatitis. Its anti-inflammatory properties and potential for improving endothelial function provide additional cardiovascular benefits. When combined with a heart-healthy lifestyle, ZYROVA F can significantly improve overall cardiovascular health and reduce the risk of cardiovascular events.

How to use ZYROVA F 5MG TABLET 10'SArrow

  • ZYROVA F 5MG TABLET 10'S is a combination medication containing Fenofibrate and Rosuvastatin, primarily used to manage high cholesterol and triglyceride levels in the blood. It's crucial to use this medication exactly as prescribed by your doctor. The usual starting dose is one tablet daily, taken orally. Do not crush, chew, or break the tablet; swallow it whole with a full glass of water.
  • Consistency is key for the effectiveness of ZYROVA F. Take the tablet at the same time each day to help you remember. It can be taken with or without food; however, taking it with food might improve absorption. If you experience stomach upset, taking it with food may also alleviate this discomfort.
  • Before starting ZYROVA F, inform your doctor about all your medical conditions, especially liver or kidney disease, gallbladder problems, or any muscle disorders. Also, disclose all other medications you're taking, including over-the-counter drugs, herbal supplements, and vitamins, as drug interactions can occur. Regular blood tests are necessary to monitor your cholesterol levels and liver function while you're on this medication. Follow your doctor's instructions carefully, and do not stop taking ZYROVA F without consulting them, even if you feel better. Stopping the medication abruptly may cause your cholesterol levels to rise again. In addition to medication, adopting a healthy lifestyle, including a balanced diet and regular exercise, is essential for managing cholesterol levels effectively.
  • If you miss a dose of ZYROVA F, take it as soon as you remember, unless it's almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one. If you have any questions or concerns about using ZYROVA F, consult your doctor or pharmacist for clarification. Store ZYROVA F 5MG TABLET 10'S at room temperature, away from heat, moisture, and direct sunlight. Keep it out of reach of children and pets.

Quick Tips for ZYROVA F 5MG TABLET 10'SArrow

  • **Take ZYROVA F 5MG TABLET 10'S as prescribed:** Always adhere to your doctor's instructions regarding dosage and timing. Consistency is key for optimal results. Do not self-adjust the dose or stop taking the medication without consulting your healthcare provider, as this could lead to adverse effects or a recurrence of your condition. This medication is typically prescribed for a specific duration, and completing the full course is crucial for its effectiveness.
  • **Be mindful of dietary considerations:** While taking ZYROVA F 5MG TABLET 10'S, be aware that certain foods or beverages might interact with the medication. Your doctor or pharmacist can provide guidance on any specific dietary restrictions or recommendations. For instance, grapefruit juice can sometimes interfere with the absorption of certain medications, so it's wise to inquire about potential interactions.
  • **Understand potential side effects:** Familiarize yourself with the possible side effects associated with ZYROVA F 5MG TABLET 10'S. Common side effects might include muscle pain, headache, or digestive issues. If you experience any severe or persistent side effects, promptly inform your doctor. They can assess the situation and provide appropriate medical advice. Knowing what to expect can help alleviate anxiety and ensure timely intervention if needed.
  • **Stay hydrated and maintain a healthy lifestyle:** Adequate hydration is essential for overall well-being and can also help minimize certain side effects associated with medications. Aim to drink plenty of water throughout the day. Additionally, maintaining a healthy lifestyle through regular exercise and a balanced diet can complement the effects of ZYROVA F 5MG TABLET 10'S and promote overall health.
  • **Store ZYROVA F 5MG TABLET 10'S properly:** To ensure the medication's effectiveness and safety, store it according to the instructions provided on the packaging or by your pharmacist. Typically, this involves keeping it in a cool, dry place away from direct sunlight and moisture. Keep the medication out of reach of children and pets to prevent accidental ingestion.

FAQs

What is Zyrova F 5mg Tablet 10's and what is it used for?Arrow

Zyrova F 5mg Tablet 10's is a combination medicine primarily used to lower elevated levels of cholesterol and triglycerides, reducing the risk of heart diseases.

What are the active ingredients in Zyrova F 5mg Tablet 10's?Arrow

Zyrova F 5mg Tablet 10's contains Rosuvastatin and Fenofibrate as active ingredients.

What are the common side effects of Zyrova F 5mg Tablet 10's?Arrow

Common side effects of Zyrova F 5mg Tablet 10's may include muscle pain, abdominal pain, nausea, headache, and fatigue.

Can I take Zyrova F 5mg Tablet 10's with or without food?Arrow

Zyrova F 5mg Tablet 10's can be taken with or without food, but it is important to take it at the same time each day.

What happens if I miss a dose of Zyrova F 5mg Tablet 10's?Arrow

If you miss a dose of Zyrova F 5mg Tablet 10's, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule.

Is Zyrova F 5mg Tablet 10's safe for pregnant women?Arrow

Zyrova F 5mg Tablet 10's is not recommended for pregnant women as it may harm the unborn baby.

Is Zyrova F 5mg Tablet 10's safe for breastfeeding women?Arrow

Zyrova F 5mg Tablet 10's is not recommended for breastfeeding women as it may be excreted in breast milk and harm the baby.

How should I store Zyrova F 5mg Tablet 10's?Arrow

Store Zyrova F 5mg Tablet 10's at room temperature, away from direct sunlight and moisture. Keep it out of reach of children and pets.

Is it safe to consume alcohol with Zyrova F 5mg Tablet 10's?Arrow

Consuming alcohol with Zyrova F 5mg Tablet 10's may increase the risk of liver problems. Therefore, it is advisable to limit or avoid alcohol consumption.

Can Zyrova F 5mg Tablet 10's interact with other medications?Arrow

Zyrova F 5mg Tablet 10's can interact with certain medications, such as blood thinners and some antacids. Inform your doctor about all your medications to avoid any potential interactions.

How long does it take for Zyrova F 5mg Tablet 10's to start working?Arrow

It may take a few weeks for Zyrova F 5mg Tablet 10's to start working. It is important to take the medication regularly and follow your doctor's instructions to see improvements in cholesterol levels.

Does Zyrova F 5mg Tablet 10's cause muscle pain?Arrow

Yes, Zyrova F 5mg Tablet 10's may cause muscle pain in some patients. Inform your doctor if you experience severe muscle pain or weakness.

Can I break or chew Zyrova F 5mg Tablet 10's?Arrow

Zyrova F 5mg Tablet 10's should be swallowed whole and should not be broken or chewed unless instructed by your doctor.

Is Zyrova F 5mg Tablet 10's safe for long-term use?Arrow

Zyrova F 5mg Tablet 10's can be used for the duration prescribed by your doctor. Regular check-ups are important to monitor any potential side effects during long-term use.

What happens if I overdose on Zyrova F 5mg Tablet 10's?Arrow

If you suspect that you have overdosed on Zyrova F 5mg Tablet 10's, seek immediate medical attention or call a poison control center.

References

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FDA label for rosuvastatin calcium (ZYROVA contains rosuvastatin). This document provides detailed information on clinical pharmacology, indications, dosage, contraindications, warnings, precautions, adverse reactions, and drug interactions.

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DrugBank entry for Rosuvastatin. Provides comprehensive information including chemical structure, mechanism of action, pharmacokinetics, and therapeutic uses.

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Rosuvastatin: a comprehensive review of the evidence and current place in therapy. Expert Opinion on Pharmacotherapy. This article reviews the clinical efficacy and safety profile of rosuvastatin.

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European Medicines Agency (EMA) assessment report for Crestor (rosuvastatin). Although not ZYROVA specifically, it provides scientific discussion and benefit-risk assessment of rosuvastatin.

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Rosuvastatin Use and Risk of Incident Diabetes Mellitus: A Systematic Review and Meta-Analysis. Journal of the American Heart Association. Research article on the risk of diabetes associated with rosuvastatin.

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ZYROVA F 5MG TABLET 10'S

ZYROVA F 5MG TABLET 10'S

MRP

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₹172.47

15 % OFF

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