ACUGREL AS 150MG TABLET 10'S

How ACUGREL AS 150MG TABLET 10'S Works

• ACUGREL AS 150MG TABLET 10'S is a dual antiplatelet therapy combining two potent medications: Aspirin and Clopidogrel. This combination is crucial in preventing blood clots, especially in individuals at high risk of cardiovascular events like heart attack or stroke. Understanding how each component works is key to appreciating the overall effectiveness of ACUGREL AS.
• Aspirin, also known as acetylsalicylic acid, acts as an antiplatelet agent by irreversibly inhibiting cyclooxygenase (COX-1) enzyme. COX-1 is responsible for producing thromboxane A2, a substance that promotes platelet aggregation (the clumping of platelets together). By inhibiting COX-1, Aspirin reduces the production of thromboxane A2, thereby hindering platelet aggregation. This action effectively thins the blood and reduces the likelihood of clot formation in arteries.
• Clopidogrel, on the other hand, belongs to a class of drugs called thienopyridines. It works by selectively and irreversibly blocking the P2Y12 receptor on platelet cell membranes. This receptor is crucial for platelet activation and aggregation stimulated by adenosine diphosphate (ADP). When ADP binds to the P2Y12 receptor, it triggers a cascade of events leading to platelet activation and the formation of blood clots. Clopidogrel effectively prevents ADP from binding to the P2Y12 receptor, thus inhibiting platelet activation and aggregation.
• The synergistic effect of Aspirin and Clopidogrel provides a more comprehensive antiplatelet action compared to either drug alone. Aspirin inhibits thromboxane A2 production, while Clopidogrel blocks the ADP pathway. This dual inhibition significantly reduces the risk of arterial thrombosis, which is the formation of blood clots in arteries. This is particularly important in individuals who have undergone percutaneous coronary intervention (PCI), such as stent placement, or those with acute coronary syndrome (ACS).
• ACUGREL AS 150MG TABLET 10'S helps to keep blood flowing smoothly through the arteries, preventing clots that can cause heart attack, stroke, or other serious cardiovascular problems. It is important to take this medication exactly as prescribed by your doctor, as incorrect dosage or discontinuation can increase the risk of adverse events.

Like all medicines, ACUGREL AS 150MG TABLET 10'S can cause side effects, although not everybody gets them. **Common Side Effects (may affect up to 1 in 10 people):** * Increased bleeding tendency * Bruising * Nosebleeds * Gastrointestinal bleeding **Uncommon Side Effects (may affect up to 1 in 100 people):** * Headache * Dizziness * Tingling or numbness * Skin rash * Itching * Stomach ulcers * Constipation * Diarrhea * Vomiting * Nausea * Gas **Rare Side Effects (may affect up to 1 in 1,000 people):** * Severe bleeding * Low blood cell counts **Very Rare Side Effects (may affect up to 1 in 10,000 people):** * Allergic reactions (e.g., swelling of the face, lips, tongue, or throat, difficulty breathing or swallowing) * Liver problems * Kidney problems * Joint pain * Muscle pain * Fever **Other possible side effects:** * Bleeding in the brain * Bleeding in the eyes * Bleeding in the lungs **If you experience any serious side effects, stop taking ACUGREL AS 150MG TABLET 10'S and seek immediate medical attention.** This includes: * Signs of an allergic reaction * Unexpected bleeding that is severe or prolonged * Signs of a blood clot, such as chest pain, shortness of breath, or sudden weakness on one side of the body This is not a complete list of side effects. If you notice any other unusual symptoms, contact your doctor or pharmacist.

• If you miss a dose of Acugrel AS 150mg Tablet 10's, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

• Keep ACUGREL AS 150MG TAB 1X10 away from the reach of children and pets.
• Store ACUGREL AS 150MG TAB 1X10 at room temperature.

• Take ACUGREL AS 150MG TABLET 10'S exactly as prescribed by your doctor. Do not change the dose or stop taking it without consulting your healthcare provider, as this can increase your risk of serious cardiovascular events like heart attack or stroke. This medication is usually taken once daily with or without food.
• Inform your doctor about all other medications, supplements, and herbal products you are currently taking before starting ACUGREL AS 150MG TABLET 10'S. This is crucial because ACUGREL AS 150MG TABLET 10'S can interact with certain medications, such as NSAIDs (like ibuprofen or naproxen), blood thinners (like warfarin), and some antidepressants, potentially increasing the risk of bleeding.
• Be vigilant for signs of bleeding while taking ACUGREL AS 150MG TABLET 10'S. Common side effects include easy bruising, nosebleeds, bleeding gums, and prolonged bleeding from cuts. If you experience any unusual or excessive bleeding, such as blood in your urine or stool, black, tarry stools, or vomiting blood, seek immediate medical attention.
• If you are scheduled for any surgery, dental procedure, or invasive medical test, inform your doctor or dentist that you are taking ACUGREL AS 150MG TABLET 10'S. Your doctor may advise you to stop taking the medication temporarily before the procedure to minimize the risk of bleeding. Follow their instructions carefully regarding when to stop and restart the medication.
• Lifestyle modifications can significantly enhance the benefits of ACUGREL AS 150MG TABLET 10'S. Maintain a healthy diet low in saturated fat and cholesterol, engage in regular physical activity (as advised by your doctor), avoid smoking, and manage your blood pressure and cholesterol levels. These measures will help improve your overall cardiovascular health and reduce your risk of future events. Limit alcohol consumption as it may increase the risk of bleeding.

• ACUGREL AS 150MG TABLET 10'S can be taken with or without food. Food does not significantly affect the absorption of the medication.