LOSATAN AM TABLET 10'S

How LOSATAN AM TABLET 10'S Works

• LOSATAN AM TABLET 10'S is a combination medication containing Losartan and Amlodipine, designed to manage hypertension (high blood pressure). These two active ingredients work synergistically to lower blood pressure more effectively than either medication could alone. Losartan belongs to a class of drugs called angiotensin II receptor blockers (ARBs), while Amlodipine is a calcium channel blocker.
• Losartan works by blocking the action of angiotensin II, a naturally occurring substance in the body that can cause blood vessels to constrict. Angiotensin II binds to receptors in the walls of blood vessels, leading to vasoconstriction (narrowing of blood vessels) and an increase in blood pressure. By blocking these receptors, Losartan prevents angiotensin II from exerting its effects. This allows blood vessels to relax and widen, reducing the resistance against which the heart has to pump, thereby lowering blood pressure. Losartan also helps reduce the release of aldosterone, a hormone that causes the kidneys to retain sodium and water, which further contributes to lower blood pressure.
• Amlodipine, on the other hand, works by inhibiting the influx of calcium ions into vascular smooth muscle and cardiac muscle. Calcium is essential for muscle contraction. By blocking calcium channels in the smooth muscle cells of blood vessels, Amlodipine causes these muscles to relax. This relaxation leads to vasodilation (widening of blood vessels), particularly in the arteries. The reduced vascular resistance decreases the afterload on the heart, meaning the heart doesn't have to work as hard to pump blood. This action primarily affects arterial smooth muscle, reducing blood pressure with less effect on the veins.
• The combined action of Losartan and Amlodipine provides a comprehensive approach to blood pressure management. Losartan addresses the hormonal component of blood pressure regulation by blocking angiotensin II, while Amlodipine directly relaxes blood vessels by blocking calcium influx. Together, they provide a more effective reduction in blood pressure than either drug could achieve alone. This synergistic effect makes LOSATAN AM TABLET 10'S a powerful tool in managing hypertension and reducing the risk of cardiovascular events such as heart attack, stroke, and kidney problems. The combination helps to maintain lower blood pressure levels throughout the day, offering consistent control of hypertension.

Like all medicines, LOSATAN AM TABLET 10'S can cause side effects, although not everybody gets them. **Common side effects (may affect up to 1 in 10 people):** * Dizziness * Headache * Fatigue * Swelling of ankles, feet, or fingers (edema) * Cough * Nasal congestion * Sore throat * Diarrhea * Nausea * Abdominal pain * Muscle cramps * Increased potassium in the blood * Low blood pressure **Uncommon side effects (may affect up to 1 in 100 people):** * Sleepiness * Palpitations * Rapid heart rate * Chest pain * Shortness of breath * Upset stomach * Constipation * Skin rash * Itching * Hair loss * Impotence * Increased need to urinate, especially at night * Gout * Loss of appetite * Anxiety * Nervousness * Paresthesia (numbness or tingling) * Vertigo **Rare side effects (may affect up to 1 in 1,000 people):** * Increased liver enzymes * Increased bilirubin (a bile pigment) in the blood * Hypersensitivity **Very rare side effects (may affect up to 1 in 10,000 people):** * Inflammation of the liver (hepatitis) **Not known (frequency cannot be estimated from the available data):** * Severe allergic reaction (anaphylaxis) * Muscle pain * Kidney problems * Low sodium levels in the blood * Angioedema (sudden swelling of the face, lips, tongue or throat that may cause difficulty breathing or swallowing). If this happens, stop taking LOSATAN AM TABLET 10'S and tell your doctor immediately or go to the emergency room of your nearest hospital.

• If you miss a dose of Losatan AM Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep LOSATAN AM TAB 1X10 away from the reach of children and pets.
• Store LOSATAN AM TAB 1X10 at room temperature.

• Take LOSATAN AM TABLET 10'S exactly as prescribed by your doctor. Do not change the dosage or stop taking the medication without consulting your healthcare provider. Consistency is key for managing your blood pressure effectively.
• LOSATAN AM TABLET 10'S can be taken with or without food. Choose a consistent time each day to take your tablet to help you remember. If you have stomach upset, taking it with food might help.
• Before starting LOSATAN AM TABLET 10'S, inform your doctor about all other medications you are taking, including over-the-counter drugs, herbal remedies, and supplements. Certain medications can interact with LOSATAN AM and affect its efficacy or increase the risk of side effects. Pay special attention to NSAIDs like ibuprofen or naproxen.
• Regularly monitor your blood pressure while taking LOSATAN AM TABLET 10'S. Keep a log of your blood pressure readings and share it with your doctor during your check-ups. This helps your doctor assess how well the medication is working and make necessary adjustments.
• Be aware of potential side effects of LOSATAN AM TABLET 10'S, such as dizziness, lightheadedness, or swelling in your ankles and feet. If you experience any persistent or bothersome side effects, contact your doctor promptly. Also, avoid sudden changes in posture to minimize dizziness.
• Maintain a healthy lifestyle while taking LOSATAN AM TABLET 10'S. This includes eating a balanced diet low in sodium, engaging in regular physical activity, maintaining a healthy weight, and limiting alcohol consumption. These lifestyle modifications can complement the effects of the medication and improve your overall cardiovascular health.
• If you miss a dose of LOSATAN AM TABLET 10'S, take it as soon as you remember unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.
• Store LOSATAN AM TABLET 10'S at room temperature away from moisture and heat. Keep the medication out of the reach of children and pets. Proper storage ensures the medication remains effective until its expiration date.
• If you are scheduled for any surgery, including dental procedures, inform your doctor or dentist that you are taking LOSATAN AM TABLET 10'S. The medication may need to be temporarily discontinued before the procedure to prevent complications.
• Attend all scheduled follow-up appointments with your doctor while taking LOSATAN AM TABLET 10'S. These appointments are essential for monitoring your blood pressure, assessing your overall health, and making any necessary adjustments to your treatment plan.

• LOSATAN AM TABLET 10'S can be taken with or without food. However, it is advisable to take it at a consistent time each day to maintain steady blood levels and maximize its effectiveness. If you experience stomach upset, taking it with food may help alleviate this.
• Avoid consuming large amounts of grapefruit or grapefruit juice while taking LOSATAN AM TABLET 10'S, as grapefruit can interact with amlodipine, potentially increasing the drug's levels in your body and leading to enhanced side effects. If you have any concerns, consult your doctor or pharmacist.