ZILOS AM TABLET 10'S

How ZILOS AM TABLET 10'S Works

• ZILOS AM TABLET 10'S is a combination medication designed to effectively manage hypertension (high blood pressure) by utilizing the synergistic effects of its two active ingredients: Amlodipine and Losartan. Each component works through distinct mechanisms to achieve optimal blood pressure control.
• Amlodipine, a calcium channel blocker, primarily targets the smooth muscle cells lining the blood vessels. These cells contract when calcium ions enter them, causing the vessels to narrow and blood pressure to rise. Amlodipine selectively blocks these calcium channels, preventing calcium from entering the smooth muscle cells. This results in the relaxation of the blood vessels, a process known as vasodilation. By widening the blood vessels, Amlodipine reduces the resistance against which the heart has to pump, thereby lowering blood pressure.
• Losartan, on the other hand, is an angiotensin II receptor blocker (ARB). Angiotensin II is a potent vasoconstrictor, meaning it causes blood vessels to narrow. It also stimulates the release of aldosterone, a hormone that promotes sodium and water retention by the kidneys, further increasing blood volume and blood pressure. Losartan works by selectively blocking the angiotensin II receptors, preventing angiotensin II from binding to these receptors. This action inhibits the vasoconstrictive effects of angiotensin II, allowing blood vessels to relax. Additionally, by blocking angiotensin II's action, Losartan reduces aldosterone release, leading to decreased sodium and water retention and a subsequent reduction in blood volume and pressure.
• The combined action of Amlodipine and Losartan provides a comprehensive approach to blood pressure management. Amlodipine directly relaxes blood vessels, while Losartan counteracts the effects of angiotensin II, a key regulator of blood pressure. This dual mechanism helps to achieve a greater reduction in blood pressure compared to using either medication alone. Furthermore, the combination may also help to mitigate some of the side effects associated with each individual drug. For example, Amlodipine can sometimes cause peripheral edema (swelling in the ankles and feet), while Losartan may help to reduce this effect. By working together, these two medications offer a balanced and effective strategy for controlling hypertension and reducing the risk of cardiovascular complications.
• In summary, ZILOS AM TABLET 10'S effectively lowers blood pressure by combining Amlodipine's ability to relax blood vessels with Losartan's ability to block the effects of angiotensin II. This synergistic action provides a comprehensive and balanced approach to managing hypertension.

Possible side effects of ZILOS AM Tablet may include: * **Common Side Effects:** Headache, dizziness, fatigue, nausea, flushing (feeling of warmth), ankle swelling, palpitations (irregular heartbeat), sleepiness. * **Uncommon Side Effects:** Abdominal pain, indigestion, diarrhea, constipation, muscle cramps, joint pain, back pain, blurred vision, double vision, ringing in the ears (tinnitus), skin rash, itching, hair loss, mood changes (including anxiety and depression), increased urination, impotence (erectile dysfunction), breast enlargement in men (gynecomastia), weight gain. * **Rare Side Effects:** Severe allergic reaction (anaphylaxis), liver problems (including jaundice), heart attack, stroke, low blood pressure, gum swelling. **Note:** This is not an exhaustive list. If you experience any unusual or severe side effects, consult your doctor immediately.

• If you miss a dose of ZILOS AM TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double the dose to catch up.

• Keep ZILOS AM TAB 1X10 away from the reach of children and pets.
• Store ZILOS AM TAB 1X10 at room temperature.

• Take ZILOS AM TABLET 10'S exactly as prescribed by your doctor. Do not change the dosage or stop taking the medication without consulting your physician, even if you feel better. This medication is typically prescribed to manage high blood pressure and/or chest pain (angina), and consistent use is crucial for its effectiveness.
• Be mindful of potential side effects. Common side effects of ZILOS AM TABLET 10'S can include headache, dizziness, fatigue, swelling in the ankles or feet, and flushing. If these side effects are bothersome or persistent, inform your doctor. More serious side effects, though rare, require immediate medical attention.
• Monitor your blood pressure regularly while taking ZILOS AM TABLET 10'S, especially during the initial weeks of treatment or after a dosage adjustment. Keep a record of your blood pressure readings and share them with your doctor during your check-ups. This helps in assessing the medication's effectiveness and adjusting the treatment plan if needed.
• Inform your doctor about all other medications, supplements, and herbal products you are taking. ZILOS AM TABLET 10'S can interact with other drugs, potentially affecting their efficacy or increasing the risk of side effects. This is particularly important if you are taking medications for heart conditions, diabetes, or other chronic illnesses.
• Maintain a healthy lifestyle to support the effectiveness of ZILOS AM TABLET 10'S. This includes following a balanced diet low in sodium and saturated fats, engaging in regular physical activity, maintaining a healthy weight, and avoiding excessive alcohol consumption. Quitting smoking is also strongly recommended, as smoking can worsen cardiovascular health.

• Avoid consuming excessive amounts of grapefruit or grapefruit juice while taking ZILOS AM TABLET 10'S, as it may interfere with the medication's effectiveness.