LUPISULIN M 50/50 40IU VIAL 10 ML

How LUPISULIN M 50/50 40IU VIAL 10 ML Works

• LUPISULIN M 50/50 is a premixed insulin formulation containing both rapid-acting (soluble) insulin and intermediate-acting (isophane) insulin. This combination helps manage blood sugar levels in people with diabetes mellitus. Here's how it works:
• **Rapid-Acting Insulin (Soluble Insulin):** This component of LUPISULIN M 50/50 starts working quickly, typically within 30 minutes after injection. It mimics the bolus insulin that the pancreas would normally release after a meal. Its primary function is to help the body use the glucose (sugar) that comes from the food you eat. By facilitating the uptake of glucose into cells, it prevents excessive rise in blood sugar levels after meals.
• **Intermediate-Acting Insulin (Isophane Insulin):** This type of insulin has a slower onset of action and a longer duration. It provides a background level of insulin, also known as basal insulin, which helps to control blood sugar levels between meals and overnight. Isophane insulin works by forming crystals that are slowly absorbed into the bloodstream, providing a sustained release of insulin over a longer period. This sustained release helps to maintain stable blood sugar levels throughout the day and night.
• **Overall Action:** LUPISULIN M 50/50 is designed to provide both immediate and prolonged insulin activity. The rapid-acting component addresses post-meal glucose spikes, while the intermediate-acting component manages baseline glucose levels. The 50/50 ratio indicates the proportion of each type of insulin in the mixture. This pre-mixed formulation offers convenience for those who need both types of insulin but prefer fewer injections.
• **Mechanism of Action:** Insulin, in general, works by binding to insulin receptors on cells throughout the body. This binding triggers a cascade of intracellular events that facilitate the uptake of glucose from the bloodstream into cells, especially muscle and fat cells. Inside the cells, glucose can be used for energy or stored as glycogen (in the liver and muscles) or as fat. Insulin also inhibits the liver from producing more glucose, further helping to lower blood sugar levels.
• **Important Considerations:** The specific onset, peak, and duration of action of LUPISULIN M 50/50 can vary depending on factors like the dose, injection site, individual metabolism, and physical activity level. It is crucial to follow your doctor's instructions carefully regarding dosage, timing of injections, and monitoring of blood sugar levels. Regular monitoring is essential to ensure that the insulin is effectively controlling your blood sugar and to adjust the dosage if needed. Always consult with your healthcare provider for personalized advice on managing your diabetes with LUPISULIN M 50/50.

Possible side effects of LUPISULIN M 50/50 40IU VIAL 10 ML include: * Hypoglycemia (low blood sugar): Symptoms may include sweating, shakiness, dizziness, anxiety, blurred vision, rapid heartbeat, headache, hunger, confusion, and difficulty concentrating. * Hyperglycemia (high blood sugar): Symptoms may include increased thirst and urination, blurred vision, fatigue, and weight loss. * Injection site reactions: Redness, swelling, itching, pain, or lumps at the injection site. * Lipodystrophy: Changes in fat tissue at the injection site (either thickening or thinning). * Allergic reactions: Rash, itching, hives, swelling of the face, lips, or tongue, difficulty breathing. * Weight gain * Edema (swelling), especially in the ankles and feet. * Visual disturbances * Peripheral neuropathy (nerve damage causing pain, numbness, or tingling). * Rare but serious side effects may include hypokalemia (low potassium levels) and sodium retention. This is not an exhaustive list, and other side effects may occur. Contact your doctor or pharmacist if you experience any unusual symptoms.

• If you miss a dose of Lupisulin M 50/50, it's important to monitor your blood sugar levels closely.
• Take your next dose as soon as you remember, but only if it's well before your next scheduled meal. If it's close to your next mealtime, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to compensate for the missed one, as this can significantly increase your risk of hypoglycemia (low blood sugar).
• Consult your doctor or diabetes educator for personalized advice on managing missed doses, as individual circumstances may vary.

• Keep LUPISULIN M 50/50 40IU VIAL 10ML away from the reach of children and pets.
• Store LUPISULIN M 50/50 40IU VIAL 10ML in a refrigerator (2 - 8°C). Do not freeze.

• **Understand Your Insulin Type:** LUPISULIN M 50/50 is a premixed insulin, containing 50% rapid-acting insulin and 50% intermediate-acting insulin. This combination helps manage blood sugar levels both after meals and throughout the day. Understanding this balance is crucial for effective diabetes management. Discuss with your doctor how this specific mix suits your dietary habits and lifestyle.
• **Proper Storage is Key:** Always store your unopened LUPISULIN M 50/50 vials in the refrigerator (2°C to 8°C). Avoid freezing. Once opened, the vial can be stored at room temperature (below 25°C) for up to 28 days. Protect it from direct heat and light. Discard the vial after 28 days, even if it still contains insulin, to ensure potency and effectiveness. Record the date you opened the vial to keep track.
• **Administer Correctly:** Inject LUPISULIN M 50/50 subcutaneously (under the skin), usually 15-30 minutes before a meal. Rotate injection sites within the same general area (e.g., abdomen, thigh, or arm) to prevent lipodystrophy (skin thickening or pitting). Ensure you are using the correct insulin syringe and needle, and follow your doctor's or diabetes educator's instructions carefully. Priming the pen or syringe before each injection is important for accurate dosing.
• **Monitor Blood Sugar Regularly:** Frequent blood sugar monitoring is essential when using LUPISULIN M 50/50. Check your blood sugar levels before meals and at bedtime, and as recommended by your healthcare provider. Keep a record of your blood sugar readings to help identify patterns and adjust your insulin dosage accordingly. Discuss any significant changes or concerns with your doctor promptly.
• **Be Aware of Hypoglycemia:** Hypoglycemia (low blood sugar) is a potential side effect of insulin therapy. Learn to recognize the symptoms of hypoglycemia, which may include sweating, shakiness, dizziness, hunger, confusion, and rapid heartbeat. Always carry a source of fast-acting sugar (e.g., glucose tablets, juice) with you to treat hypoglycemia quickly. If you experience frequent or severe episodes of hypoglycemia, consult your doctor to adjust your insulin regimen.

• LUPISULIN M 50/50's effects can be influenced by what and when you eat. Consistent meal timing and carbohydrate intake are crucial for managing blood sugar levels while using this medication.
• Skipping meals or having irregular eating habits can lead to hypoglycemia (low blood sugar). Ensure you eat regular meals and snacks as directed by your doctor.
• Consuming alcohol while using LUPISULIN M 50/50 can significantly lower your blood sugar levels, potentially leading to dangerous hypoglycemia. Avoid or moderate alcohol intake and monitor your blood sugar closely if you do drink.
• Pay attention to the carbohydrate content of your meals. Work with your doctor or a dietitian to understand how different foods affect your blood sugar and adjust your LUPISULIN M 50/50 dosage accordingly.
• Inform your doctor about any changes in your diet, as dosage adjustments may be necessary.