OZOMET VG1 TABLET 15'S

How OZOMET VG1 TABLET 15'S Works

• OZOMET VG1 Tablet is a combination medicine designed to manage blood sugar levels in adults with type 2 diabetes mellitus. It combines three active ingredients: Metformin, Voglibose, and Glimepiride, each working through different mechanisms to achieve comprehensive glycemic control. This triple combination addresses multiple facets of insulin resistance and glucose metabolism, making it effective in managing elevated blood sugar.
• Metformin, a cornerstone in type 2 diabetes treatment, primarily reduces hepatic glucose production. The liver is a significant source of glucose, especially during fasting states. Metformin inhibits gluconeogenesis, the process by which the liver synthesizes glucose from non-carbohydrate sources like amino acids and glycerol. Additionally, Metformin enhances insulin sensitivity in peripheral tissues such as muscles, allowing them to utilize glucose more effectively. This dual action helps lower both fasting and postprandial blood glucose levels. Furthermore, Metformin slows down the absorption of glucose from the intestines, which contributes to its overall glucose-lowering effect. It achieves this by increasing the activity of an enzyme called AMP-activated protein kinase (AMPK), which plays a crucial role in regulating energy balance at the cellular level.
• Voglibose, an alpha-glucosidase inhibitor, functions by delaying the absorption of carbohydrates from the small intestine. It competitively inhibits alpha-glucosidase enzymes located in the brush border of the small intestine. These enzymes are responsible for breaking down complex carbohydrates into simpler sugars like glucose, which can then be absorbed into the bloodstream. By inhibiting these enzymes, Voglibose slows down the postprandial rise in blood glucose levels. This is particularly beneficial for managing the glycemic excursion that occurs after meals. Voglibose's action is localized to the gut, minimizing systemic effects and making it a well-tolerated option for many patients.
• Glimepiride, a sulfonylurea, stimulates the release of insulin from the pancreatic beta cells. It works by binding to the sulfonylurea receptor on these cells, which leads to the closure of ATP-sensitive potassium channels. This closure depolarizes the cell membrane, causing an influx of calcium ions. The increased intracellular calcium triggers the exocytosis of insulin-containing granules. Glimepiride is particularly effective in lowering blood glucose levels when taken before meals, as it helps to augment the body's natural insulin response to food intake. It enhances the ability of the pancreas to secrete insulin in response to elevated glucose levels.
• In summary, OZOMET VG1 Tablet combines the actions of Metformin to reduce hepatic glucose production and improve insulin sensitivity, Voglibose to delay carbohydrate absorption, and Glimepiride to stimulate insulin release. This synergistic effect provides comprehensive glycemic control, helping patients achieve and maintain target blood sugar levels. Regular monitoring of blood glucose levels and adherence to dietary and exercise recommendations are essential for optimal management of type 2 diabetes mellitus.

Common side effects of OZOMET VG1 Tablet may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, hypoglycemia (low blood sugar), headache, dizziness, and weakness. Less common but potentially serious side effects can include lactic acidosis (symptoms include rapid breathing, stomach pain, and muscle cramps), allergic reactions (rash, itching, swelling), liver problems (yellowing of the skin or eyes), and changes in blood counts. In rare cases, it may cause pancreatitis. Always consult your doctor if you experience any unusual or severe symptoms while taking this medication.

• If you miss a dose of OZOMET VG1 TABLET 15'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep OZOMET VG1 TAB 1X15 away from the reach of children and pets.
• Store OZOMET VG1 TAB 1X15 at room temperature.

• Take OZOMET VG1 TABLET 15'S exactly as prescribed by your doctor. Do not change the dosage or stop taking the medication without consulting your healthcare provider. Consistent adherence to the prescribed regimen optimizes blood sugar control.
• OZOMET VG1 TABLET 15'S is most effective when taken with meals. This helps to regulate the absorption of glucose and minimize fluctuations in blood sugar levels after eating. Try to maintain a consistent meal schedule each day.
• Monitor your blood sugar levels regularly as directed by your doctor. Keeping a log of your blood sugar readings helps you and your healthcare provider assess how well OZOMET VG1 TABLET 15'S is working and make necessary adjustments to your treatment plan.
• Inform your doctor about all other medications, supplements, and herbal remedies you are taking. Certain substances can interact with OZOMET VG1 TABLET 15'S, affecting its efficacy or increasing the risk of side effects. This includes over-the-counter drugs and even some foods.
• Maintain a healthy lifestyle by eating a balanced diet and exercising regularly. OZOMET VG1 TABLET 15'S works best when combined with lifestyle modifications. Regular physical activity and a diet low in processed sugars and saturated fats can significantly improve blood sugar control and overall health.

• It is advisable to take OZOMET VG1 TABLET 15'S with or immediately after meals to avoid stomach upset. Avoid excessive alcohol consumption while taking this medicine, as it can increase the risk of low blood sugar (hypoglycemia).