ROZAVEL F 5/160MG TABLET 15'S

How ROZAVEL F 5/160MG TABLET 15'S Works

• ROZAVEL F 5/160MG TABLET is a combination medication designed to manage cholesterol levels and reduce the risk of cardiovascular events. It combines two active ingredients: Rosuvastatin and Fenofibrate, each working through different mechanisms to achieve optimal results. Rosuvastatin belongs to a class of drugs called statins, while Fenofibrate is a fibrate.
• Rosuvastatin primarily functions by inhibiting an enzyme called HMG-CoA reductase. This enzyme is crucial in the liver's production of cholesterol. By blocking HMG-CoA reductase, Rosuvastatin reduces the amount of cholesterol the liver produces. This leads to a decrease in LDL cholesterol (often referred to as 'bad' cholesterol) in the bloodstream. Lowering LDL cholesterol is vital because high levels contribute to the formation of plaque in the arteries, a process known as atherosclerosis. Additionally, Rosuvastatin can modestly increase HDL cholesterol (often referred to as 'good' cholesterol), which helps remove LDL cholesterol from the arteries.
• Fenofibrate works by activating a protein called peroxisome proliferator-activated receptor alpha (PPARα). PPARα is found in various tissues, including the liver and muscles. When activated, PPARα increases the production of lipoprotein lipase (LPL). LPL is an enzyme that breaks down triglycerides, a type of fat in the blood. By increasing LPL activity, Fenofibrate helps lower triglyceride levels. Elevated triglycerides can also contribute to the risk of cardiovascular disease. Furthermore, Fenofibrate can also increase HDL cholesterol levels.
• The combination of Rosuvastatin and Fenofibrate in ROZAVEL F 5/160MG TABLET provides a dual approach to managing lipid profiles. Rosuvastatin effectively lowers LDL cholesterol, while Fenofibrate reduces triglycerides and increases HDL cholesterol. This synergistic effect helps to comprehensively address multiple lipid abnormalities, making it particularly beneficial for individuals with mixed dyslipidemia (high LDL cholesterol, high triglycerides, and low HDL cholesterol).
• By effectively managing cholesterol and triglyceride levels, ROZAVEL F 5/160MG TABLET helps to slow down or prevent the progression of atherosclerosis. This reduces the risk of serious cardiovascular events such as heart attack, stroke, and peripheral artery disease. It's important to remember that ROZAVEL F 5/160MG TABLET should be used in conjunction with a healthy lifestyle, including a balanced diet, regular exercise, and smoking cessation, to maximize its benefits.

Like all medicines, ROZAVEL F 5/160MG TABLET 15'S can cause side effects, although not everybody gets them. **Common side effects (may affect up to 1 in 10 people):** * Headache * Muscle pain or weakness * Feeling sick (nausea) * Constipation * Dizziness * Increased blood sugar levels * Inflammation of nasal passage and throat **Uncommon side effects (may affect up to 1 in 100 people):** * Skin rash, itching, hives * Increased protein in the urine **Rare side effects (may affect up to 1 in 1,000 people):** * Severe muscle problems (rhabdomyolysis), which can lead to kidney damage * Inflammation of the liver (hepatitis) * Pancreatitis (inflammation of the pancreas) **Very rare side effects (may affect up to 1 in 10,000 people):** * Jaundice (yellowing of the skin and eyes) * Memory loss * Peripheral neuropathy (nerve damage causing numbness, tingling or pain) * Gynecomastia (enlargement of breasts in men) **Other possible side effects:** * Erectile dysfunction * Depression * Breathing problems, including persistent cough and/or shortness of breath or fever * Tendon problems, including tendon rupture **Important:** This is not an exhaustive list. If you experience any unusual symptoms while taking ROZAVEL F 5/160MG TABLET 15'S, consult your doctor or pharmacist immediately.

• If you miss a dose of ROZAVEL F 5/160MG TABLET 15'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep ROZAVEL F 5/160MG TAB 1X15 away from the reach of children and pets.
• Store ROZAVEL F 5/160MG TAB 1X15 at room temperature.

• **Take ROZAVEL F 5/160MG TABLET 15'S as prescribed by your doctor:** Adhere strictly to the dosage and timing instructions provided by your healthcare provider. Do not self-adjust the dose or discontinue the medication without consulting your doctor, as this can affect the medication's efficacy and your overall health. This ensures that the medicine works effectively to manage your cholesterol and triglyceride levels.
• **Maintain a healthy lifestyle while taking ROZAVEL F 5/160MG TABLET 15'S:** This medication works best when combined with a balanced diet low in saturated fats and cholesterol, regular exercise, and avoiding smoking. These lifestyle modifications can significantly improve your cardiovascular health and enhance the benefits of the medication. Lifestyle changes play a crucial role in managing cholesterol and overall well-being.
• **Be aware of potential side effects:** While ROZAVEL F 5/160MG TABLET 15'S is generally well-tolerated, some individuals may experience side effects such as muscle pain, stomach upset, or liver abnormalities. Report any unusual or persistent symptoms to your doctor promptly. Regular monitoring through blood tests might be necessary to check liver function and muscle health. Immediate reporting of side effects ensures timely management and prevents complications.
• **Inform your doctor about other medications and medical conditions:** Before starting ROZAVEL F 5/160MG TABLET 15'S, inform your doctor about all other medications you are taking, including over-the-counter drugs, herbal supplements, and any pre-existing medical conditions such as liver or kidney disease. This information helps your doctor avoid potential drug interactions and adjust the dosage accordingly. A complete medical history is essential for safe and effective treatment.
• **Store ROZAVEL F 5/160MG TABLET 15'S properly:** Keep the medication in its original container, stored at room temperature, away from moisture and direct sunlight. Ensure it is out of reach of children and pets. Proper storage maintains the drug's stability and effectiveness. Check the expiration date before use and discard any expired medication safely.

• ROZAVEL F 5/160MG TABLET 15'S can be taken with or without food. However, it is important to maintain a consistent diet while taking this medication. Avoid consuming large amounts of grapefruit or grapefruit juice, as it can increase the levels of rosuvastatin in your blood and potentially increase the risk of side effects. It's also advisable to limit your intake of high-fat foods, as this medication is used to manage cholesterol and triglycerides, and a diet high in saturated and trans fats can counteract its effectiveness. Consult your doctor or pharmacist for personalized dietary advice while taking ROZAVEL F 5/160MG TABLET 15'S.