DIAMICRON XR 60MG TABLET 14'S

How DIAMICRON XR 60MG TABLET 14'S Works

• DIAMICRON XR 60MG TABLET 14'S is an oral hypoglycemic (anti-diabetic) medicine used to treat type 2 diabetes mellitus, especially when diet and exercise alone are not sufficient to control blood sugar levels. Its active ingredient, gliclazide, belongs to the sulfonylurea class of medications. Here’s a detailed explanation of how DIAMICRON XR works:
• 1. **Stimulating Insulin Release:** Gliclazide primarily works by stimulating the beta cells in the pancreas to release more insulin. Insulin is a hormone that helps glucose (sugar) move from the blood into cells, where it can be used for energy. In type 2 diabetes, either the pancreas doesn't produce enough insulin, or the body's cells are resistant to insulin's effects. Gliclazide helps overcome the insulin deficiency by prompting the pancreas to release more of it.
• 2. **Mechanism of Action at the Cellular Level:** Specifically, gliclazide binds to sulfonylurea receptors on the beta cells of the pancreas. This binding closes potassium channels, which leads to depolarization of the cell membrane. Depolarization opens calcium channels, allowing calcium ions to enter the beta cells. The increased intracellular calcium triggers the release of insulin from the beta cells.
• 3. **Extended Release Formulation:** DIAMICRON XR is formulated as an extended-release tablet. This means that the gliclazide is released slowly and steadily over a prolonged period, typically 24 hours. This helps to maintain a more consistent level of insulin in the blood throughout the day, reducing the risk of blood sugar spikes after meals and minimizing the fluctuations in blood glucose levels. This controlled release helps in better glycemic control with a single daily dose.
• 4. **Improved Glycemic Control:** By increasing insulin secretion, DIAMICRON XR helps lower blood glucose levels after meals and throughout the day. This improved glycemic control helps reduce the long-term complications associated with diabetes, such as nerve damage (neuropathy), kidney damage (nephropathy), eye damage (retinopathy), and cardiovascular problems.
• 5. **Secondary Effects (Less Prominent):** While the primary action of gliclazide is to stimulate insulin release, it may also have some secondary effects that contribute to its anti-diabetic action. These include: Enhancing insulin sensitivity in peripheral tissues (making cells more responsive to insulin), Reducing glucose production in the liver (gluconeogenesis). However, these effects are generally less significant than its insulin-releasing action.
• In summary, DIAMICRON XR 60MG TABLET 14'S works by stimulating the pancreas to release more insulin, primarily through its action on beta cells. The extended-release formulation ensures a steady release of gliclazide, providing consistent blood sugar control throughout the day. This mechanism helps lower blood glucose levels and reduce the risk of diabetes-related complications. It is crucial to take this medication as prescribed by your doctor and to follow a healthy diet and exercise plan to manage your diabetes effectively.

Like all medicines, DIAMICRON XR 60MG TABLET 14'S can cause side effects, although not everybody gets them. The most common side effect is hypoglycemia (low blood sugar). If you experience symptoms such as sweating, paleness, hunger, trembling, anxiety, fast heartbeat, headache, confusion, or difficulty concentrating, it's important to take action to raise your blood sugar levels quickly. Other possible side effects include: * **Common (may affect up to 1 in 10 people):** * Abdominal pain * Nausea * Vomiting * Diarrhea * Constipation * **Uncommon (may affect up to 1 in 100 people):** * Elevated liver enzymes * Skin rash * Itching * Hives * **Rare (may affect up to 1 in 1,000 people):** * Decreased blood cell counts (e.g., anemia, thrombocytopenia, leukopenia) * Severe skin reactions (e.g., Stevens-Johnson syndrome, toxic epidermal necrolysis) * Liver problems (e.g., hepatitis, jaundice) * **Very rare (may affect up to 1 in 10,000 people):** * Visual disturbances * **Not known (frequency cannot be estimated from the available data):** * Changes in blood glucose levels (hyperglycemia) * Indigestion It is important to contact your doctor immediately if you experience any serious side effects or any side effects that persist or worsen.

• If you miss a dose of DIAMICRON XR 60MG TABLET 14'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep DIAMICRON XR 60MG TAB 1X14 away from the reach of children and pets.
• Store DIAMICRON XR 60MG TAB 1X14 at room temperature.

• **Take DIAMICRON XR 60MG TABLET 14'S as prescribed by your doctor:** Always adhere to the dosage and timing instructions provided by your healthcare provider. Do not alter the dose or stop taking the medication without consulting them, even if you feel better. Consistency is key for managing your blood sugar levels effectively. This helps ensure a steady release of the medication, preventing sudden spikes or drops in blood sugar.
• **Monitor your blood sugar regularly:** Regular blood glucose monitoring is crucial while taking DIAMICRON XR 60MG TABLET 14'S. Keep a log of your readings and share it with your doctor during your appointments. This helps them assess the effectiveness of the medication and make any necessary adjustments to your treatment plan. Understanding how your body responds to the medication is vital for optimal diabetes management.
• **Follow a healthy diet:** Maintain a balanced diet that is low in sugar and refined carbohydrates. Focus on incorporating whole grains, fruits, vegetables, and lean protein sources into your meals. A healthy diet works synergistically with DIAMICRON XR 60MG TABLET 14'S to control blood sugar levels and improve overall health. Consider consulting a registered dietitian for personalized meal planning advice.
• **Engage in regular physical activity:** Aim for at least 30 minutes of moderate-intensity exercise most days of the week. Regular physical activity helps improve insulin sensitivity, lower blood sugar levels, and promote weight management. Choose activities you enjoy, such as walking, swimming, or cycling, to make exercise a sustainable part of your lifestyle. Remember to check your blood sugar before, during, and after exercise, as physical activity can affect blood glucose levels.
• **Be aware of the symptoms of hypoglycemia:** DIAMICRON XR 60MG TABLET 14'S can sometimes cause low blood sugar (hypoglycemia). Be familiar with the symptoms, which may include sweating, shaking, dizziness, confusion, and rapid heartbeat. If you experience any of these symptoms, consume a fast-acting source of sugar, such as glucose tablets or fruit juice, and inform your doctor. Carrying a source of fast-acting sugar with you at all times is a good practice.
• **Stay hydrated:** Drink plenty of water throughout the day. Adequate hydration helps your body function properly and can assist in regulating blood sugar levels. Dehydration can sometimes mimic symptoms of high blood sugar, so staying hydrated is essential for accurate self-monitoring and overall well-being.
• **Inform your doctor about other medications and medical conditions:** Before starting DIAMICRON XR 60MG TABLET 14'S, inform your doctor about all other medications you are taking, including over-the-counter drugs, supplements, and herbal remedies. Also, disclose any other medical conditions you have, such as kidney or liver problems. This information helps your doctor ensure that DIAMICRON XR 60MG TABLET 14'S is safe and appropriate for you.
• **Limit alcohol consumption:** Alcohol can interfere with blood sugar control and increase the risk of hypoglycemia. If you choose to drink alcohol, do so in moderation and with food. Discuss your alcohol consumption habits with your doctor to receive personalized guidance.
• **Manage Stress:** High stress levels can impact blood sugar control. Find healthy ways to manage stress, such as practicing relaxation techniques (meditation, deep breathing), engaging in hobbies, or spending time with loved ones. Consistent stress management can positively influence your overall well-being and help maintain stable blood sugar levels.
• **Attend regular check-ups:** Regular follow-up appointments with your doctor are essential for monitoring your progress and making any necessary adjustments to your treatment plan. These check-ups allow your doctor to assess your blood sugar control, check for potential complications, and provide ongoing support and guidance.

• DIAMICRON XR 60MG TABLET 14'S is generally recommended to be taken with meals to help prevent low blood sugar (hypoglycemia).
• Consistent timing with meals is important. Take it at the same time each day, preferably with breakfast.
• Avoid skipping meals while taking this medication.
• Be cautious about alcohol consumption, as it can increase the risk of low blood sugar.