SITAGLYN M 50/500MG TABLET 10'S

How SITAGLYN M 50/500MG TABLET 10'S Works

• SITAGLYN M 50/500MG TABLET 10'S is a combination medication containing Sitagliptin and Metformin, designed to manage blood sugar levels in individuals with type 2 diabetes. It works through complementary mechanisms of action to improve glycemic control.
• Sitagliptin belongs to a class of drugs called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors). DPP-4 is an enzyme that inactivates incretin hormones. Incretins, such as GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide), are released from the gut in response to food intake. These hormones stimulate insulin release from the pancreas and decrease glucagon secretion from the liver, both of which help to lower blood sugar levels. Sitagliptin works by inhibiting DPP-4, thus increasing the levels and activity of incretin hormones in the body. This results in enhanced insulin secretion and reduced glucagon secretion in a glucose-dependent manner, meaning it primarily works when blood sugar is high, reducing the risk of hypoglycemia.
• Metformin, on the other hand, is a biguanide that works primarily by decreasing glucose production in the liver. It reduces hepatic glucose output by inhibiting gluconeogenesis (the process by which the liver makes glucose from non-carbohydrate sources) and glycogenolysis (the breakdown of glycogen into glucose). Metformin also improves insulin sensitivity in peripheral tissues such as muscle, allowing cells to utilize glucose more effectively. Additionally, it slows down the absorption of glucose from the intestines after a meal.
• In summary, SITAGLYN M 50/500MG TABLET 10'S works through a dual mechanism: Sitagliptin enhances the action of incretin hormones to increase insulin release and decrease glucagon secretion, while Metformin reduces glucose production in the liver and improves insulin sensitivity. This combination helps to lower both fasting and postprandial (after-meal) blood sugar levels, leading to better overall glycemic control in patients with type 2 diabetes. It is usually prescribed along with diet and exercise to achieve optimal results. The synergistic action of these two drugs makes SITAGLYN M an effective option for managing type 2 diabetes when a single medication is not sufficient.

Common side effects of SITAGLYN M 50/500MG TABLET may include nausea, vomiting, diarrhea, stomach pain, loss of appetite, and metallic taste. Some patients might experience headache, dizziness, or drowsiness. Less common but potentially serious side effects are lactic acidosis (symptoms include weakness, muscle pain, trouble breathing, stomach pain with nausea and vomiting, dizziness, irregular heartbeat), pancreatitis (severe stomach pain radiating to your back, with nausea and vomiting), and allergic reactions (rash, itching, swelling). Rarely, it may cause hypoglycemia (low blood sugar) especially when taken with other diabetes medications (symptoms include sweating, shaking, rapid heartbeat, hunger, blurred vision, tingling lips, lightheadedness), or severe joint pain. Kidney problems and heart failure have also been reported in rare cases. Please consult your doctor immediately if you experience any persistent or severe side effects.

• If you miss a dose of SITAGLYN M 50/500MG TABLET, take it as soon as you remember. However, if it is close to your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.
• Missing a dose can cause fluctuations in your blood sugar levels, so try to take the medicine at the same time each day to maintain consistent control.

• Keep SITAGLYN M 50/500MG TAB 1X10 away from the reach of children and pets.
• Store SITAGLYN M 50/500MG TAB 1X10 at room temperature.

• Take SITAGLYN M 50/500MG TABLET 10'S exactly as prescribed by your doctor. Do not change the dosage or stop taking the medication without consulting your healthcare provider. Consistent adherence to the prescribed regimen is crucial for effective blood sugar control.
• SITAGLYN M 50/500MG TABLET 10'S should be taken with food to minimize the risk of gastrointestinal side effects such as nausea, vomiting, or diarrhea. Taking it with a meal helps in better absorption and reduces stomach upset.
• Monitor your blood sugar levels regularly as directed by your doctor while taking SITAGLYN M 50/500MG TABLET 10'S. Keeping a log of your blood sugar readings can help you and your doctor assess how well the medication is working and make necessary adjustments to your treatment plan. Discuss these readings with your healthcare provider during your check-ups.
• Inform your doctor about all other medications, supplements, and herbal products you are taking before starting SITAGLYN M 50/500MG TABLET 10'S. Certain medications can interact with sitagliptin and metformin, potentially affecting their efficacy or increasing the risk of side effects. Be particularly cautious about medications that affect blood sugar levels or kidney function.
• Maintain a healthy lifestyle by following a balanced diet and engaging in regular physical activity while taking SITAGLYN M 50/500MG TABLET 10'S. This tablet works best when combined with lifestyle modifications. A healthy diet low in sugars and saturated fats, along with regular exercise, can significantly improve blood sugar control and overall health. Aim for at least 30 minutes of moderate-intensity exercise most days of the week.
• Stay hydrated by drinking plenty of water throughout the day while on SITAGLYN M 50/500MG TABLET 10'S, unless your doctor has advised otherwise due to other medical conditions. Adequate hydration supports kidney function, which is important as metformin is processed through the kidneys.
• Be aware of the symptoms of hypoglycemia (low blood sugar) and hyperglycemia (high blood sugar) while taking SITAGLYN M 50/500MG TABLET 10'S. Hypoglycemia symptoms may include shakiness, sweating, confusion, and dizziness, while hyperglycemia symptoms include increased thirst, frequent urination, and blurred vision. Know how to manage these conditions and inform your family and close contacts about what to do in case of an emergency. Carry a source of quick-acting glucose with you at all times in case of hypoglycemia.

• SITAGLYN M 50/500MG TABLET 10'S should be taken with food to decrease the chance of an upset stomach.
• Avoid excessive alcohol consumption while taking this medication, as it may increase the risk of lactic acidosis, a serious side effect.
• Inform your doctor about your diet, especially if you are on a restricted or specific diet plan.