SITARA M 50/500MG TABLET 10'S

How SITARA M 50/500MG TABLET 10'S Works

• SITARA M 50/500MG TABLET 10'S is a combination medicine designed to manage type 2 diabetes mellitus effectively. It combines Sitagliptin and Metformin, each working through different mechanisms to control blood sugar levels.
• Sitagliptin belongs to a class of drugs called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors). DPP-4 inhibitors work by increasing the amount of incretin hormones released in the body. Incretins are hormones released by the intestine in response to food intake. They increase insulin release from the pancreas and decrease glucagon secretion from the alpha cells of pancreas. By increasing and prolonging the activity of incretin hormones, sitagliptin increases insulin release in response to high blood glucose and reduces glucagon secretion. The net effect is better glucose control.
• Metformin, on the other hand, is a biguanide. It primarily works by decreasing glucose production in the liver and improving the body's sensitivity to insulin. Metformin reduces the amount of glucose the liver releases into the bloodstream, thus lowering fasting blood sugar levels. It also enhances insulin sensitivity in peripheral tissues (muscle and fat), allowing cells to uptake and use glucose more effectively. Furthermore, Metformin slows down the absorption of glucose from the intestines after a meal, which prevents sharp spikes in blood sugar levels. It does not cause weight gain or hypoglycemia when used alone.
• When Sitagliptin and Metformin are combined, they provide a complementary and synergistic approach to managing blood sugar levels. Sitagliptin enhances insulin secretion and reduces glucagon levels, mainly after meals, while Metformin reduces hepatic glucose production and improves insulin sensitivity throughout the day. This dual action helps maintain stable blood sugar levels throughout the day and night.
• In summary, SITARA M 50/500MG TABLET 10'S works by addressing multiple key defects in type 2 diabetes: insulin deficiency, insulin resistance, and increased hepatic glucose production. It helps to lower both fasting and postprandial (after-meal) blood sugar levels, improving overall glycemic control in individuals with type 2 diabetes when used in conjunction with diet and exercise.

Common side effects of Sitara M 50/500mg Tablet may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, and hypoglycemia (low blood sugar). Other possible side effects are headache, dizziness, fatigue, and skin rash. In rare cases, it can cause lactic acidosis, a serious metabolic condition, or affect liver function. Long-term use may lead to vitamin B12 deficiency. Consult your doctor if you experience any persistent or severe side effects.

• If you miss a dose of SITARA M 50/500MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

• Keep SITARA M 50/500MG TAB 1X10 away from the reach of children and pets.
• Store SITARA M 50/500MG TAB 1X10 at room temperature.

• **Take Sitara M Regularly & Consistently:** For optimal blood sugar control, take Sitara M 50/500mg tablet at the same time each day. Consistency helps maintain steady drug levels in your body, maximizing its effectiveness. Missing doses can lead to fluctuations in blood sugar levels.
• **Follow Dietary Guidelines:** Sitara M works best when combined with a healthy diet. Focus on consuming balanced meals with controlled portions of carbohydrates. Prioritize whole grains, lean proteins, and plenty of fruits and vegetables. Consult a registered dietitian or your doctor for a personalized meal plan.
• **Monitor Your Blood Sugar Regularly:** Keep track of your blood sugar levels as directed by your doctor. Regular monitoring helps you and your doctor understand how Sitara M and your lifestyle choices are affecting your diabetes control. Share your readings with your healthcare provider during your appointments.
• **Be Aware of Hypoglycemia Symptoms:** Sitara M, especially when taken with other diabetes medications, can sometimes cause hypoglycemia (low blood sugar). Learn to recognize the symptoms such as sweating, shakiness, dizziness, rapid heartbeat, and confusion. Carry a source of fast-acting sugar like glucose tablets or juice to treat a hypoglycemic episode promptly. Inform your family and friends about the symptoms of hypoglycemia and how to assist you if needed.
• **Stay Active:** Regular physical activity enhances the effectiveness of Sitara M. Aim for at least 30 minutes of moderate-intensity exercise most days of the week. Activities like brisk walking, cycling, or swimming can improve insulin sensitivity and help lower blood sugar levels. Consult your doctor before starting any new exercise program.
• **Inform Your Doctor About Other Medications:** Disclose all medications, supplements, and herbal remedies you are taking to your doctor. Some medications can interact with Sitara M, affecting its efficacy or increasing the risk of side effects. This includes over-the-counter drugs and herbal supplements.
• **Stay Hydrated:** Drink plenty of water throughout the day. Adequate hydration helps maintain overall health and can indirectly impact blood sugar control. Aim for at least 8 glasses of water daily, unless your doctor advises otherwise.
• **Avoid Alcohol or Limit Intake:** Alcohol can interfere with blood sugar control and increase the risk of hypoglycemia, especially when taking Sitara M. If you choose to drink alcohol, do so in moderation and with food. Discuss alcohol consumption with your doctor.
• **Store Sitara M Properly:** Store Sitara M 50/500mg tablets in a cool, dry place away from direct sunlight and moisture. Keep it out of reach of children and pets. Check the expiration date before taking the medication.
• **Attend Regular Check-ups:** Schedule regular appointments with your doctor for check-ups and monitoring. These visits allow your doctor to assess your progress, adjust your medication if needed, and address any concerns you may have regarding your diabetes management.

• SITARA M 50/500MG TABLET 10'S can be taken with or without food, but it is generally recommended to take it with food to reduce the risk of gastrointestinal side effects such as nausea, vomiting, or diarrhea.
• Avoid excessive alcohol consumption while taking this medication, as it can increase the risk of lactic acidosis, a rare but serious side effect.
• There are no specific food items that are known to interact negatively with SITARA M 50/500MG TABLET 10'S. However, maintaining a consistent diet can help manage blood sugar levels effectively.