SITAXA M 50MG/1000MG TABLET 15'S

How SITAXA M 50MG/1000MG TABLET 15'S Works

• SITAXA M 50MG/1000MG TABLET 15'S is a combination medicine designed to manage blood sugar levels in individuals with type 2 diabetes. It contains two active ingredients: Sitagliptin and Metformin, each working through different mechanisms to achieve optimal glycemic control.
• Sitagliptin belongs to a class of drugs called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors). DPP-4 is an enzyme that breaks down incretin hormones. Incretin hormones, such as GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide), play a crucial role in regulating blood sugar. They stimulate insulin release from the pancreas when blood sugar levels are high and reduce glucagon secretion from the liver. Glucagon is a hormone that raises blood sugar levels. By inhibiting DPP-4, Sitagliptin increases the levels of active incretin hormones in the body. This leads to enhanced insulin secretion, reduced glucagon secretion, and ultimately, lower blood sugar levels, particularly after meals. Sitagliptin works in a glucose-dependent manner, meaning its effects are more pronounced when blood sugar is elevated, reducing the risk of hypoglycemia (low blood sugar).
• Metformin, on the other hand, is a biguanide that works primarily by decreasing glucose production in the liver. It achieves this by suppressing hepatic gluconeogenesis, the process by which the liver converts non-carbohydrate sources into glucose. Metformin also improves insulin sensitivity in peripheral tissues, such as muscles, allowing them to utilize glucose more effectively. Additionally, Metformin slows down the absorption of glucose from the intestines into the bloodstream. Unlike some other diabetes medications, Metformin does not stimulate insulin secretion directly, which minimizes the risk of hypoglycemia when used alone. It can also lead to modest weight loss and is generally considered a first-line treatment for type 2 diabetes.
• When combined in SITAXA M, Sitagliptin and Metformin offer a dual approach to managing blood sugar. Sitagliptin enhances insulin secretion and reduces glucagon, while Metformin reduces glucose production in the liver and improves insulin sensitivity. This synergistic effect helps to achieve better blood sugar control than either medication could achieve alone. The combination addresses multiple aspects of type 2 diabetes, including insulin resistance, impaired insulin secretion, and excessive glucose production.
• It's crucial to use SITAXA M 50MG/1000MG TABLET 15'S as directed by your healthcare provider. Dosage and timing are determined based on individual needs and response to treatment. Regular monitoring of blood sugar levels is necessary to assess the effectiveness of the medication and make any necessary adjustments. Lifestyle modifications, such as diet and exercise, are also essential components of diabetes management and work in conjunction with SITAXA M to achieve optimal health outcomes.

Common side effects of SITAXA M 50MG/1000MG TABLET may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, and hypoglycemia (low blood sugar). Other possible side effects are headache, dizziness, fatigue, constipation, upper respiratory tract infection, and joint pain. Serious but rare side effects may include lactic acidosis, pancreatitis, and allergic reactions like rash, itching, or swelling. In very rare cases, liver problems or vitamin B12 deficiency can occur with long-term use.

• If you miss a dose of SITAXA M 50MG/1000MG TABLET 15'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep SITAXA M 50/1000MG TAB 1X15 away from the reach of children and pets.
• Store SITAXA M 50/1000MG TAB 1X15 at room temperature.

• Take SITAXA M 50MG/1000MG TABLET 15'S exactly as prescribed by your doctor. Do not change the dosage or stop taking the medication without consulting your healthcare provider, as this can affect your blood sugar levels.
• SITAXA M combines two medications: sitagliptin and metformin. Sitagliptin enhances insulin release after a meal and reduces the amount of sugar your liver makes, while metformin reduces glucose production in the liver and improves your body's sensitivity to insulin. This dual action helps in better blood sugar control.
• Take SITAXA M with meals to minimize the risk of stomach upset, a common side effect of metformin. Consistent timing with meals also helps maintain steady blood sugar levels throughout the day. If you experience persistent nausea, vomiting, or diarrhea, inform your doctor.
• Regularly monitor your blood sugar levels as directed by your doctor or diabetes educator. Keeping a log of your blood sugar readings will help you and your healthcare provider assess how well the medication is working and make necessary adjustments to your treatment plan. Discuss any unusual fluctuations with your doctor promptly.
• Inform your doctor about all other medications, supplements, and herbal remedies you are taking, as they may interact with SITAXA M. Certain medications, such as diuretics, corticosteroids, and thyroid medications, can affect blood sugar levels and may require dosage adjustments. Be particularly cautious when taking over-the-counter medications, and always check with your pharmacist or doctor for potential interactions.
• Stay hydrated by drinking plenty of water throughout the day, especially if you experience diarrhea or vomiting. Adequate hydration helps maintain kidney function and prevent dehydration, which can exacerbate diabetes symptoms. Avoid sugary drinks, as they can negatively impact blood sugar control.
• Be aware of the symptoms of hypoglycemia (low blood sugar), such as sweating, shakiness, dizziness, and confusion. Always carry a source of fast-acting glucose, such as glucose tablets or fruit juice, to quickly raise your blood sugar if these symptoms occur. Inform your family and friends about the signs of hypoglycemia and how to assist you if needed.
• Maintain a healthy lifestyle through a balanced diet and regular physical activity. A diet rich in whole grains, fruits, vegetables, and lean protein, combined with at least 30 minutes of moderate-intensity exercise most days of the week, can significantly improve blood sugar control and overall health. Consult with a registered dietitian or certified diabetes educator for personalized guidance.
• Attend regular check-ups with your doctor, including eye exams and foot exams, to monitor for any diabetes-related complications. Early detection and treatment of complications can help prevent long-term health problems. Discuss any new symptoms or concerns with your doctor promptly.
• Store SITAXA M in a cool, dry place away from direct sunlight and moisture. Keep the medication out of reach of children and pets. Do not use the medication if the packaging is damaged or the tablets appear discolored or altered. Dispose of unused medication properly according to local regulations. Always check the expiration date before taking the medication.

• SITAXA M 50MG/1000MG TABLET 15'S can be taken with or without food, but it is generally recommended to take it with food to minimize the risk of gastrointestinal side effects such as nausea or upset stomach.
• Avoid excessive alcohol consumption while taking SITAXA M 50MG/1000MG TABLET 15'S, as it may increase the risk of lactic acidosis (a serious metabolic complication) and can also affect blood sugar control. Moderation is key.
• There are no specific foods that are known to interact negatively with SITAXA M 50MG/1000MG TABLET 15'S. However, maintaining a balanced and consistent diet is important for managing blood sugar levels effectively.