ACOTREXED-500 INJECTION
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ACOTREXED-500 INJECTION
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ACOTREXED-500 INJECTION

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ACOTREXED-500 INJECTION

By ACCORD PHARMA

MRP

2828

₹2828

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Product DetailsArrow

About ACOTREXED-500 INJECTION

  • ACOTREXED-500 INJECTION is an anticancer medicine containing the active ingredient Pemetrexed. It belongs to the medication class known as an antifolate agent. It is used to treat non-small cell lung cancer and malignant pleural mesothelioma (cancers of the lungs and chest). This medicine is given alone or in combination with another anticancer medicine, such as cisplatin. Your doctor may prescribe corticosteroids, folic acid, and vitamin B12 to limit the side effects. ACOTREXED-500 INJECTION works by interfering with the growth of cancer cells, eventually destroying them or slowing their spread. It's a powerful medication that requires careful monitoring and adherence to your doctor's instructions to manage potential side effects effectively.
  • Blood tests will be taken before each infusion to determine whether your kidney and liver functions are adequate and whether you have enough blood cells to receive this medicine. Before starting treatment with ACOTREXED-500 INJECTION, it is very important to tell your physician if you currently or previously had any medical conditions of kidney problems, heart disorders, or fluid accumulation in the lungs. Report to your doctor if you recently had or currently having radiotherapy or any vaccination before taking this medication. This ensures that ACOTREXED-500 INJECTION is safe and appropriate for you.
  • Inform your doctor immediately if you are planning to get pregnant or think you may be pregnant. Use effective birth control during the treatment and at least six months after the last dose of ACOTREXED-500 INJECTION. In men, it is recommended not to father a child during and up to 3 months after the treatment. So it is advised to get suggestions about fertility concerns from your doctor. This medication is not recommended for adolescents and children under 18 years of age. It is important to discuss any fertility concerns with your healthcare provider before starting the treatment.

Uses of ACOTREXED-500 INJECTION

  • Malignant pleural mesothelioma, a rare and aggressive cancer affecting the lining of the lungs, requires specialized treatment approaches. Early detection and comprehensive management are crucial for improving patient outcomes in cases of malignant pleural mesothelioma.
  • Non-small cell lung carcinoma, a prevalent form of lung cancer, encompasses various subtypes and treatment strategies. Accurate diagnosis and staging are essential for determining the most appropriate course of action for individuals diagnosed with non-small cell lung carcinoma.

Side Effects of ACOTREXED-500 INJECTIONArrow

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Serious side effects include: Blood infection, Severe allergic reaction, Breathlessness, intense chest pain or cough with bloody sputum, Reduced neutrophil granulocytes (white blood cells), Kidney failure, Pharyngitis (a sore throat) and Abnormal liver function. Common side effects include: Fatigue, Nausea, vomiting, diarrhea, Redness, swelling or sores in the mouth, Loss of appetite, sensation, Reduced hemoglobin level, Increased skin pigmentation, Watery and inflamed eyes, taste change, Fever, Muscle weakness, Dehydration, Constipation, Skin rash and Hair loss.

  • Blood infection
  • Severe allergic reaction
  • Breathlessness, intense chest pain or cough with bloody sputum
  • Reduced neutrophil granulocytes (white blood cells)
  • Kidney failure
  • Pharyngitis (a sore throat)
  • Abnormal liver function
  • Fatigue
  • Nausea, vomiting, diarrhea
  • Redness, swelling or sores in the mouth
  • Loss of appetite, sensation
  • Reduced hemoglobin level
  • Increased skin pigmentation
  • Watery and inflamed eyes, taste change
  • Fever
  • Muscle weakness
  • Dehydration
  • Constipation
  • Skin rash
  • Hair loss

Safety Advice for ACOTREXED-500 INJECTIONArrow

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Pregnancy

UNSAFE

Do not take ACOTREXED-500 INJECTION if you are pregnant because it may cause harm to the unborn baby. Consult your doctor before starting the treatment.

Dosage of ACOTREXED-500 INJECTIONArrow

  • ACOTREXED-500 INJECTION is administered intravenously, meaning it's given directly into a vein through an infusion. This ensures the medication is quickly and effectively distributed throughout your body. Due to the specific requirements of this administration, it is crucial that a qualified healthcare professional administers the injection. Self-administration is strictly prohibited.
  • The dosage and frequency of ACOTREXED-500 INJECTION will be carefully determined by your physician. Several factors influence this decision, including the nature and severity of your medical condition, your overall health status, and your response to the treatment. Because individual needs vary, the dosage regimen will be tailored specifically to you to achieve the best possible outcome. Your doctor will continuously monitor your progress and adjust the dosage as needed.
  • It's important to follow your doctor's instructions precisely regarding the administration schedule. Do not attempt to alter the dosage or frequency on your own, as this could potentially lead to adverse effects or reduced effectiveness of the treatment. If you have any questions or concerns about your dosage, please consult with your healthcare provider.

How to store ACOTREXED-500 INJECTION?Arrow

  • Keep ACOTREXED 500MG INJ away from the reach of children and pets.
  • Store ACOTREXED 500MG INJ at room temperature.

Benefits of ACOTREXED-500 INJECTIONArrow

  • ACOTREXED-500 INJECTION is a medication that works by disrupting the process of cell division and replication. It achieves this by specifically targeting and blocking certain enzymes crucial for folate metabolism. Folate is a vital nutrient that cells need to replicate their DNA and grow. By inhibiting these enzymes, ACOTREXED-500 INJECTION effectively prevents cancer cells from multiplying and spreading. This mechanism is particularly effective against rapidly dividing cells, making it a valuable treatment option for various types of cancer. It's important to note that while ACOTREXED-500 INJECTION is powerful, it can also affect healthy cells, leading to side effects. Therefore, it is typically administered under strict medical supervision to carefully manage dosage and monitor patient response.
  • ACOTREXED-500 INJECTION's action on folate metabolism not only halts cancer cell growth but also impacts DNA synthesis, further hindering the ability of cancer cells to proliferate. This dual action makes it a potent chemotherapeutic agent. The specific enzymes targeted are essential for the production of nucleotides, the building blocks of DNA. By interfering with this process, ACOTREXED-500 INJECTION effectively starves cancer cells of the resources they need to replicate their genetic material and divide. The result is a slowdown or complete cessation of cancer cell growth.
  • The precise targeting of folate metabolism and DNA synthesis by ACOTREXED-500 INJECTION allows for a more focused attack on cancer cells while minimizing damage to other tissues. However, it's crucial to understand that folate is also essential for normal cell function, particularly in rapidly dividing tissues like bone marrow and the lining of the digestive tract. Consequently, side effects like nausea, fatigue, and lowered blood cell counts are possible. Doctors carefully weigh the benefits of ACOTREXED-500 INJECTION against these potential risks when determining the appropriate treatment plan for each patient.

How to use ACOTREXED-500 INJECTIONArrow

  • ACOTREXED-500 INJECTION is administered directly into a vein through an intravenous infusion. This ensures the medication is delivered efficiently and accurately into your bloodstream. It is crucial to understand that this injection must be administered by a qualified healthcare professional. Attempting to self-administer ACOTREXED-500 INJECTION can be dangerous and may lead to serious complications.
  • Your doctor will determine the most appropriate dosage and frequency of administration based on your specific medical condition, its severity, and your overall health. Treatment plans are highly individualized, and what works for one person may not be suitable for another. Regular monitoring and adjustments to the dosage might be necessary throughout your treatment to ensure optimal results and minimize potential side effects.
  • During the infusion, you will be closely monitored by healthcare staff to detect and manage any adverse reactions promptly. It is essential to inform your doctor about any existing medical conditions, allergies, or medications you are currently taking before starting treatment with ACOTREXED-500 INJECTION. This information will help them tailor your treatment plan and ensure your safety.

FAQs

What should I tell my doctor before starting ACOTREXED-500 INJECTION?Arrow

Before starting ACOTREXED-500 INJECTION, you should tell your doctor about any medical conditions you have, especially kidney or liver problems, as well as any medications you are taking, including over-the-counter drugs and supplements.

Can children or adults take ACOTREXED-500 INJECTION?Arrow

No, ACOTREXED-500 INJECTION is not recommended for children or adults under 18 years. Talk with your doctor for more information.

How often do I need to have blood tests while on ACOTREXED-500 INJECTION?Arrow

You will need to have regular blood tests while taking ACOTREXED-500 INJECTION to monitor your blood cell counts, blood uric acid level, and kidney function.

Can I continue my normal activities while on Alimta 500mg?Arrow

It depends on your circumstances and how you feel. You should discuss your activities and any concerns with your healthcare provider while under the treatment of Alimta 500mg.

How is Alimta 500mg administered?Arrow

A healthcare provider gives Alimta 500mg as an intravenous (IV) injection. The dose and frequency of the injections will depend on the patient's condition and other factors.

Is there any interaction of ACOTREXED-500 INJECTION with other drugs?Arrow

There is no known interaction of ACOTREXED-500 INJECTION with other drugs.

What advice should I follow while taking ACOTREXED-500 INJECTION?Arrow

Discuss your fertility problem with the doctor since, in men, it is advised not to father a child during and after the 3 months of treatment. So it is advised to get suggestions about fertility concerns. Avoid planning for the pregnancy. If you experience any symptoms mentioned as a side effect, consult your doctor immediately. Notify your doctor immediately if you have undergone any radiotherapy or taken any vaccines and other medications before starting with ACOTREXED-500 INJECTION because it might reduce the effectiveness of this medicine and may cause side effects. Inform your doctor if you have or had any history of heart disease, kidney problems,s or liver problems.

Which molecule/combination is used for making ACOTREXED-500 INJECTION?Arrow

PEMETREXED is molecule/combination used for making ACOTREXED-500 INJECTION.

For what type of Oncology ailments/diseases/conditions ACOTREXED-500 INJECTION is prescribed?Arrow

ACOTREXED-500 INJECTION is prescribed for Oncology ailments/diseases/conditions.

References

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Eagle Pharmaceuticals, US Food and Drug Administration,

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Seacross Pharmaceuticals Ltd, Electronic medicines compendium (emc),

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Ratings & Review

Good

Dhara Patva

Reviewed on 10-02-2024

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(5/5)

Genuine product....

Saurav

Reviewed on 11-01-2024

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(5/5)

Good service and discount. Help me to get a good discount on some of my daily meds

Yogesh Chawla

Reviewed on 05-08-2023

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(5/5)

Nice experience, always!

Ashutosh Buch

Reviewed on 24-02-2023

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(5/5)

It's good work and always best treatment and every time attend coustomer properly and perfectly

Shraddha Landge

Reviewed on 23-01-2024

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(5/5)


Marketer / Manufacturer Details

ACCORD PHARMA

Country of Origin -

India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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