PEMEXAR 500 INJECTION
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PEMEXAR 500 INJECTION
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PEMEXAR 500 INJECTION

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PEMEXAR 500 INJECTION

By RPG LIFE SCIENCES LIMITED

MRP

4671.8

₹3029

35.16 % OFF

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Product DetailsArrow

About PEMEXAR 500 INJECTION

  • PEMEXAR 500 INJECTION is an anticancer medicine containing the active ingredient Pemetrexed. It belongs to the medication class known as an antifolate agent. It is used to treat non-small cell lung cancer and malignant pleural mesothelioma (cancers of the lungs and chest). This medicine is given alone or in combination with another anticancer medicine, such as cisplatin. Your doctor may prescribe corticosteroids, folic acid, and vitamin B12 to limit the side effects. PEMEXAR 500 INJECTION works by interfering with the growth of cancer cells, ultimately slowing down their spread in the body. This targeted approach aims to minimize harm to healthy cells.
  • Before starting treatment with PEMEXAR 500 INJECTION, it's crucial to have blood tests to assess kidney and liver function and ensure you have sufficient blood cells to receive the medicine. Disclose any pre-existing or past medical conditions, especially kidney problems, heart disorders, or fluid accumulation in the lungs, to your physician. It's also important to inform your doctor if you've recently had or are currently undergoing radiotherapy or vaccinations. These factors can influence the safety and effectiveness of the treatment. Regular monitoring and open communication with your healthcare provider are essential for managing potential risks.
  • It is important to tell your doctor immediately if you are planning to get pregnant or think you may be pregnant. Use effective birth control during the treatment and for at least six months after the last dose of PEMEXAR 500 INJECTION. Men are advised not to father a child during treatment and for up to 3 months after the last dose. Seek fertility advice from your doctor if you have concerns. This medication is not recommended for adolescents and children under 18 years of age. Adhering to these precautions helps minimize potential risks and ensures responsible use of the medication.
  • During treatment with PEMEXAR 500 INJECTION, it's vital to maintain open communication with your healthcare team about any side effects you experience. Common side effects include nausea, fatigue, and decreased appetite. Your doctor can provide guidance on managing these side effects effectively. Additionally, it's essential to follow any dietary recommendations or lifestyle adjustments suggested by your doctor to optimize your overall well-being during treatment. Remember, your active participation in your care is crucial for achieving the best possible outcomes.
  • It is important to know that PEMEXAR 500 INJECTION is administered by a healthcare professional, usually through intravenous infusion. The dosage and frequency of treatment will be determined by your doctor based on your individual condition and response to the medicine. Attend all scheduled appointments and follow your doctor's instructions carefully. Do not discontinue treatment without consulting your doctor, even if you start feeling better. Completing the full course of treatment is essential for maximizing its effectiveness.

Uses of PEMEXAR 500 INJECTION

  • Malignant pleural mesothelioma, a rare and aggressive cancer affecting the lining of the lungs, requires specialized treatment approaches.
  • Non-small cell lung carcinoma, a prevalent form of lung cancer, necessitates comprehensive management strategies for improved patient outcomes.

Side Effects of PEMEXAR 500 INJECTIONArrow

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. **Serious:** Blood infection, Severe allergic reaction, Breathlessness, intense chest pain or cough with bloody sputum, Reduced neutrophil granulocytes (white blood cells), Kidney failure, Pharyngitis (a sore throat), Abnormal liver function. **Common:** Fatigue, Nausea, vomiting, diarrhea, Redness, swelling or sores in the mouth, Loss of appetite, sensation, Reduced hemoglobin level, Increased skin pigmentation, Watery and inflamed eyes, taste change, Fever, Muscle weakness, Dehydration, Constipation, Skin rash, Hair loss.

  • Blood infection
  • Severe allergic reaction
  • Breathlessness, intense chest pain or cough with bloody sputum
  • Reduced neutrophil granulocytes (white blood cells)
  • Kidney failure
  • Pharyngitis (a sore throat)
  • Abnormal liver function
  • Fatigue
  • Nausea, vomiting, diarrhea
  • Redness, swelling or sores in the mouth
  • Loss of appetite, sensation
  • Reduced hemoglobin level
  • Increased skin pigmentation
  • Watery and inflamed eyes, taste change
  • Fever
  • Muscle weakness
  • Dehydration
  • Constipation
  • Skin rash
  • Hair loss

Safety Advice for PEMEXAR 500 INJECTIONArrow

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Pregnancy

UNSAFE

Do not take PEMEXAR 500 INJECTION if you are pregnant because it may cause harm to the unborn baby. Consult your doctor before starting the treatment.

Dosage of PEMEXAR 500 INJECTIONArrow

  • PEMEXAR 500 INJECTION is administered directly into a vein through an intravenous infusion. This means the medication is delivered slowly and steadily into your bloodstream. If your doctor has determined that this injection is the appropriate treatment for you, it will be administered by a trained healthcare professional in a clinical setting. It is crucial not to attempt to self-administer this medication.
  • The dosage of PEMEXAR 500 INJECTION, as well as the frequency of its administration, will be determined by your physician. These factors are carefully considered based on your specific medical condition, its severity, and your individual response to the treatment. Because each person's situation is unique, the dosage regimen will be tailored to your needs. It is essential to adhere to your doctor's instructions precisely regarding the dosage and schedule of infusions to achieve the best possible therapeutic outcome.
  • Your doctor will monitor your progress throughout the treatment period and make any necessary adjustments to the dosage or frequency of administration based on your response and tolerance to the medication. Regular check-ups and open communication with your healthcare provider are vital to ensure the safe and effective use of PEMEXAR 500 INJECTION.

How to store PEMEXAR 500 INJECTION?Arrow

  • Keep PEMEXAR 500MG INJ away from the reach of children and pets.
  • Store PEMEXAR 500MG INJ at room temperature.

Benefits of PEMEXAR 500 INJECTIONArrow

  • PEMEXAR 500 INJECTION works by disrupting the crucial processes that cancer cells need to divide and multiply. Specifically, it targets and inhibits certain enzymes that are essential for folate metabolism, a process vital for cell replication. Folate is necessary for the synthesis of DNA and RNA, the building blocks of cells. By interfering with folate metabolism, PEMEXAR 500 INJECTION effectively blocks the synthesis of these critical components, thus preventing the cancer cells from replicating their DNA and dividing into new cells. This action ultimately leads to the slowing or stopping of cancer growth.
  • The medication's mechanism centers on blocking specific enzymes directly involved in DNA synthesis. Cancer cells are characterized by their rapid and uncontrolled growth, which demands a high rate of DNA replication. By inhibiting these key enzymes, PEMEXAR 500 INJECTION effectively shuts down the machinery that allows cancer cells to create new DNA. Without the ability to replicate their genetic material, cancer cells cannot divide and proliferate, leading to a reduction in tumor size and spread.
  • Furthermore, the targeted approach of PEMEXAR 500 INJECTION helps to minimize damage to healthy cells. While it's impossible to completely avoid affecting normal cells during chemotherapy, the drug's specific action on folate metabolism and DNA synthesis reduces the impact on non-cancerous tissues compared to some other chemotherapy agents. This can lead to fewer side effects and a better quality of life for patients undergoing treatment. It's important to note that this is a simplified explanation, and the precise mechanism of action can be complex.

How to use PEMEXAR 500 INJECTIONArrow

  • PEMEXAR 500 INJECTION is administered directly into a vein through intravenous infusion. This means it is delivered slowly over a period of time, allowing your body to properly absorb the medication.
  • It's crucial that this injection is administered by a qualified healthcare professional. Please do not attempt to self-administer PEMEXAR 500 INJECTION. Healthcare professionals are trained to administer injections safely and effectively, and they can monitor you for any potential side effects during the infusion.
  • The dosage and frequency of PEMEXAR 500 INJECTION will be determined by your physician based on your specific medical condition, its severity, and your response to treatment. Because each individual is unique, the dosage schedule is personalized to achieve the best possible outcome. It's essential to adhere to the schedule prescribed by your doctor.
  • During the infusion, the healthcare provider will closely monitor you for any signs of adverse reactions. This ensures that any potential problems are addressed immediately. They will also be able to answer any questions you may have about the medication or the infusion process. If you experience any discomfort or have any concerns during the infusion, be sure to let your healthcare provider know right away.

FAQs

What should I tell my doctor before starting PEMEXAR 500 INJECTION?Arrow

Before starting PEMEXAR 500 INJECTION, you should tell your doctor about any medical conditions you have, especially kidney or liver problems, as well as any medications you are taking, including over-the-counter drugs and supplements.

Can children or adults take PEMEXAR 500 INJECTION?Arrow

No, PEMEXAR 500 INJECTION is not recommended for children or adults under 18 years. Talk with your doctor for more information.

How often do I need to have blood tests while on PEMEXAR 500 INJECTION?Arrow

You will need to have regular blood tests while taking PEMEXAR 500 INJECTION to monitor your blood cell counts, blood uric acid level, and kidney function.

How much physical activity can I do while taking PEMEXAR 500 INJECTION?Arrow

It depends on your circumstances and how you feel. You should discuss your activities and any concerns with your healthcare provider while under the treatment of PEMEXAR 500 INJECTION.

How is PEMEXAR 500 INJECTION administered?Arrow

A healthcare provider gives PEMEXAR 500 INJECTION as an intravenous (IV) injection. The dose and frequency of the injections will depend on the patient's condition and other factors.

Why do I feel nauseous while taking PEMEXAR 500 INJECTION?Arrow

Nausea is a common side effect of chemotherapy drugs, including PEMEXAR 500 INJECTION. This happens because chemotherapy drugs can affect the lining of the stomach, leading to nausea and vomiting.

Does PEMEXAR 500 INJECTION interact with other drugs?Arrow

There are no known interactions of PEMEXAR 500 INJECTION with other drugs.

What advice should I seek from the doctor for PEMEXAR 500 INJECTION?Arrow

Discuss your fertility problem with the doctor since, in men, it is advised not to father a child during and after the 3 months of treatment. So it is advised to get suggestions about fertility concerns. Avoid planning for the pregnancy. If you experience any symptoms mentioned as a side effect, consult your doctor immediately. Notify your doctor immediately if you have undergone any radiotherapy or taken any vaccines and other medications before starting with Pemexar 500mg because it might reduce the effectiveness of this medicine and may cause side effects. Inform your doctor if you have or had any history of heart disease, kidney problems,s or liver problems.

What is Pemetrexed and how does it relate to PEMEXAR 500 INJECTION?Arrow

PEMETREXED is the molecule/combination used for making PEMEXAR 500 INJECTION.

What is the use of PEMEXAR 500 INJECTION in Oncology?Arrow

PEMEXAR 500 INJECTION is a medication used in Oncology.

References

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Eagle Pharmaceuticals, US Food and Drug Administration,

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Seacross Pharmaceuticals Ltd, Electronic medicines compendium (emc),

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Reviewed on 05-11-2022

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Reviewed on 08-01-2024

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Marketer / Manufacturer Details

RPG LIFE SCIENCES LIMITED

Country of Origin -

India

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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