AJADUO 25/5MG TABLET 10'S

How AJADUO 25/5MG TABLET 10'S Works

• AJADUO 25/5MG TABLET 10'S is a combination medicine containing two active ingredients: dapagliflozin and sitagliptin. These medications work through different mechanisms to lower blood sugar levels in individuals with type 2 diabetes. Dapagliflozin belongs to a class of drugs called sodium-glucose co-transporter 2 (SGLT2) inhibitors, while sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor.
• Dapagliflozin works primarily in the kidneys. In healthy individuals, the kidneys filter glucose from the blood, and then reabsorb it back into the bloodstream. Dapagliflozin blocks the action of SGLT2 in the kidneys. SGLT2 is responsible for reabsorbing glucose. By inhibiting SGLT2, dapagliflozin reduces the reabsorption of glucose, causing excess glucose to be excreted in the urine. This process lowers blood glucose levels. Because it works independently of insulin, dapagliflozin carries a lower risk of hypoglycemia (low blood sugar) compared to some other diabetes medications. In addition to lowering blood sugar, dapagliflozin can also lead to modest weight loss and blood pressure reduction in some individuals.
• Sitagliptin, on the other hand, works by enhancing the body's own ability to lower blood sugar. It belongs to a class of medications called DPP-4 inhibitors. DPP-4 is an enzyme that breaks down incretin hormones in the body. Incretin hormones, such as GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide), are released from the gut after a meal. These hormones stimulate the release of insulin from the pancreas and decrease the secretion of glucagon from the liver. Glucagon is a hormone that raises blood sugar levels. By inhibiting DPP-4, sitagliptin increases the levels of active incretin hormones in the body. This leads to increased insulin release and decreased glucagon secretion in response to elevated blood sugar levels after a meal. The overall effect is improved blood sugar control.
• In summary, AJADUO 25/5MG TABLET 10'S works through a dual mechanism. Dapagliflozin reduces glucose reabsorption in the kidneys, leading to glucose excretion in the urine. Sitagliptin enhances the action of incretin hormones, resulting in increased insulin release and decreased glucagon secretion. By targeting different pathways, these two medications work together to effectively lower blood sugar levels in people with type 2 diabetes. It's important to use this medication as part of a holistic diabetes management plan that includes lifestyle changes, like diet and exercise.

Possible side effects of AJADUO 25/5MG TABLET 10'S may include: Nausea, Vomiting, Diarrhea, Abdominal pain, Loss of appetite, Headache, Dizziness, Fatigue, Weakness, Muscle pain, Joint pain, Back pain, Skin rash, Itching, Upper respiratory tract infection, Sore throat, Runny nose, Cough, Increased blood pressure, Increased heart rate, Peripheral edema (swelling in the hands and feet), Hypoglycemia (low blood sugar), Hyperglycemia (high blood sugar), Urinary tract infection, Blurred vision, Changes in taste, Constipation, Flatulence, Indigestion, Weight gain, Anxiety, Insomnia, Depression. This is not an exhaustive list, and other side effects may occur. Contact your doctor if you experience any unusual or severe symptoms.

• If you miss a dose of AJADUO 25/5MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep AJADUO 25/5MG TAB 1X10 away from the reach of children and pets.
• Store AJADUO 25/5MG TAB 1X10 at room temperature.

• Take AJADUO 25/5MG TABLET 10'S exactly as prescribed by your doctor. Do not change the dosage or stop taking the medication without consulting your healthcare provider. Consistency is key for optimal blood sugar control. This ensures that the medication works effectively throughout the day to manage your blood glucose levels.
• AJADUO 25/5MG TABLET 10'S is typically taken once or twice daily with meals. Taking it with food helps to reduce the risk of stomach upset and also aids in the absorption of the medication. Follow your doctor's instructions regarding the timing of your doses in relation to your meals. This timed intake is crucial for preventing drastic spikes or drops in blood sugar levels.
• Monitor your blood sugar levels regularly, as directed by your doctor. Keeping a log of your blood sugar readings can help you and your healthcare provider assess how well AJADUO 25/5MG TABLET 10'S is working for you. This data is essential for making any necessary adjustments to your treatment plan. Discuss these readings with your doctor during your check-ups.
• Be aware of the potential side effects of AJADUO 25/5MG TABLET 10'S, such as nausea, diarrhea, or headache. If you experience any persistent or bothersome side effects, inform your doctor promptly. They can provide guidance on how to manage these side effects or adjust your medication if necessary. Do not ignore persistent symptoms; addressing them early can prevent complications.
• Maintain a healthy lifestyle while taking AJADUO 25/5MG TABLET 10'S. This includes eating a balanced diet, exercising regularly, and maintaining a healthy weight. These lifestyle modifications can significantly improve your blood sugar control and overall health. AJADUO works best when combined with a proactive approach to wellness and consistent lifestyle modifications.

• AJADUO 25/5MG TABLET 10'S can be taken with or without food. However, it is advisable to take it at a fixed time to maintain consistent levels of the medication in your body.
• Avoid excessive alcohol consumption while taking this medication, as it may increase the risk of side effects.