AMIXIDE H TABLET 10'S

How AMIXIDE H TABLET 10'S Works

• AMIXIDE H TABLET 10'S is a combination medication designed to manage hypertension (high blood pressure). It contains two active ingredients: Amiloride and Hydrochlorothiazide. These components work synergistically through different mechanisms to lower blood pressure effectively.
• Hydrochlorothiazide is a thiazide diuretic, commonly known as a 'water pill.' It acts primarily on the kidneys to increase the excretion of sodium and chloride ions. By promoting sodium excretion, hydrochlorothiazide reduces the amount of water retained in the body. This decrease in fluid volume leads to a reduction in blood volume, which subsequently lowers blood pressure. Hydrochlorothiazide also affects blood vessels, making them more relaxed and contributing to lower blood pressure. Its diuretic effect starts within two hours of taking the medication, reaching its peak in about four hours, and can last for up to twelve hours.
• Amiloride is a potassium-sparing diuretic. Unlike many diuretics that cause potassium loss, amiloride helps the body retain potassium. It works by blocking the epithelial sodium channel (ENaC) in the distal tubules and collecting ducts of the kidneys. This channel is responsible for sodium reabsorption, which is coupled with potassium and hydrogen ion secretion. By blocking this channel, amiloride reduces sodium reabsorption and, consequently, reduces potassium excretion. This mechanism helps to maintain potassium levels in the body, preventing hypokalemia (low potassium levels), a common side effect of many other diuretics. Amiloride begins to work within two hours, with its peak effect occurring between six and ten hours, and can last for up to twenty-four hours.
• The combination of hydrochlorothiazide and amiloride in AMIXIDE H TABLET 10'S is particularly beneficial because it addresses high blood pressure while minimizing the risk of potassium imbalance. Hydrochlorothiazide effectively lowers blood pressure by reducing fluid volume, while amiloride counteracts the potassium-wasting effect of hydrochlorothiazide. This combined action provides a balanced approach to managing hypertension. Patients taking AMIXIDE H TABLET 10'S typically experience a consistent reduction in blood pressure, helping to prevent long-term complications associated with hypertension, such as heart disease, stroke, and kidney damage. It's crucial to take this medication as directed by a healthcare professional and to regularly monitor blood pressure and potassium levels to ensure optimal therapeutic outcomes and minimize potential side effects.

Common side effects of Amixide H Tablet may include headache, dizziness, lightheadedness, fatigue, nausea, vomiting, stomach upset, diarrhea, constipation, muscle cramps, increased urination, dry mouth, and blurred vision. Less common but potentially serious side effects include allergic reactions (rash, itching, swelling), electrolyte imbalances (low potassium, low sodium), changes in blood sugar, gout, increased cholesterol, irregular heartbeat, kidney problems, liver problems, and orthostatic hypotension (sudden drop in blood pressure upon standing). Contact your doctor immediately if you experience any severe or persistent side effects.

• If you miss a dose of Amixide H Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep AMIXIDE H TAB 1X10 away from the reach of children and pets.
• Store AMIXIDE H TAB 1X10 at room temperature.

• Take AMIXIDE H TABLET 10'S exactly as prescribed by your doctor. Do not alter the dosage or frequency without consulting your healthcare provider. Consistent adherence to the prescribed regimen optimizes its effectiveness in managing your blood pressure.
• It's important to monitor your blood pressure regularly while taking AMIXIDE H TABLET 10'S. Keep a record of your readings and share them with your doctor during check-ups. This helps in assessing the medicine's effectiveness and making necessary adjustments.
• AMIXIDE H TABLET 10'S can sometimes cause dizziness or lightheadedness, especially when you first start taking it or when the dosage is increased. Stand up slowly from a sitting or lying position to minimize these effects. If dizziness persists or becomes severe, consult your doctor.
• Inform your doctor about all other medications, supplements, or herbal remedies you are currently taking before starting AMIXIDE H TABLET 10'S. Certain substances can interact with this medicine, potentially affecting its efficacy or increasing the risk of side effects. This includes over-the-counter medications and herbal supplements.
• Lifestyle modifications, such as maintaining a healthy diet, exercising regularly, and limiting alcohol consumption, can complement the effects of AMIXIDE H TABLET 10'S in managing your blood pressure. Discuss suitable lifestyle changes with your doctor or a registered dietitian for personalized recommendations. Avoid smoking while taking this medicine as smoking further increases blood pressure.

• AMIXIDE H TABLET 10'S may be taken with or without food. However, it is important to maintain a consistent diet while taking this medication. Avoid consuming excessive amounts of salt, as this can reduce the effectiveness of the medication. Also, limit your intake of alcohol, as it can increase the risk of side effects such as dizziness and lightheadedness. Consult your doctor or pharmacist if you have any questions about food interactions.