AMLOKIND L TABLET 10'S

How AMLOKIND L TABLET 10'S Works

• AMLOKIND L Tablet is a combination medication containing Amlodipine and Lisinopril. These two drugs work together to effectively lower blood pressure and improve cardiovascular health.
• Amlodipine is a calcium channel blocker. It works by relaxing and widening the blood vessels, allowing blood to flow more easily. Specifically, Amlodipine inhibits the influx of calcium ions into vascular smooth muscle and cardiac muscle. By blocking calcium entry, Amlodipine reduces the contraction of these muscles. In blood vessels, this relaxation leads to vasodilation (widening of blood vessels), which decreases peripheral vascular resistance and lowers blood pressure. In the heart, Amlodipine's effect is less pronounced in terms of reducing heart rate, but it does help to improve blood flow to the heart muscle, reducing the workload on the heart.
• Lisinopril is an angiotensin-converting enzyme (ACE) inhibitor. ACE is an enzyme in the body that converts angiotensin I to angiotensin II. Angiotensin II is a potent vasoconstrictor (a substance that narrows blood vessels) and also stimulates the release of aldosterone, a hormone that causes the kidneys to retain sodium and water. By inhibiting ACE, Lisinopril reduces the production of angiotensin II, leading to vasodilation (widening of blood vessels) and decreased aldosterone levels. This results in reduced blood pressure due to decreased vascular resistance and reduced sodium and water retention.
• The combined effect of Amlodipine and Lisinopril provides a synergistic effect in lowering blood pressure. Amlodipine's vasodilation complements Lisinopril's reduction of angiotensin II and aldosterone, resulting in a more effective and sustained reduction in blood pressure compared to either drug used alone. This combination helps to reduce the risk of cardiovascular events such as heart attack, stroke, and kidney problems associated with hypertension.
• In summary, AMLOKIND L Tablet works by Amlodipine relaxing and widening blood vessels and Lisinopril preventing the formation of a substance that narrows blood vessels and causes salt and water retention. This dual mechanism effectively lowers blood pressure and protects the cardiovascular system.

Common side effects of AMLOKIND L TABLET may include: Dizziness, Headache, Fatigue, Sleepiness, Nausea, Flushing (sense of warmth in the face, ears, neck and trunk), Palpitations, Edema (swelling), Abdominal pain, Orthostatic hypotension (sudden lowering of blood pressure on standing), Visual disturbance. Uncommon side effects may include: Anxiety, Depression, Insomnia, Peripheral neuropathy, Tremor, Vertigo, Tinnitus (ringing in the ears), Arrhythmia, Chest pain, Hypotension, Vomiting, Diarrhea, Constipation, Dry mouth, Dyspepsia (indigestion), Increased sweating, Skin rash, Muscle cramps, Joint pain, Back pain, Increased frequency of urination, Sexual dysfunction, Gynecomastia (enlargement of breasts in men), Weight gain, Weight loss, Malaise.

• If you miss a dose of AMLOKIND L TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep AMLOKIND L TAB 1X10 away from the reach of children and pets.
• Store AMLOKIND L TAB 1X10 at room temperature.

• Take AMLOKIND L exactly as your doctor prescribes. Consistency is key to managing your blood pressure effectively. Set a daily reminder if needed to help you remember.
• Be patient! It may take several weeks for AMLOKIND L to lower your blood pressure to the target level. Continue taking the medication even if you feel well.
• Lifestyle changes can significantly enhance the effects of AMLOKIND L. Adopt a low-sodium diet, exercise regularly, maintain a healthy weight, and limit alcohol consumption.
• Inform your doctor about all other medications, supplements, and herbal products you are taking. Some substances can interact with AMLOKIND L, affecting its efficacy or increasing the risk of side effects.
• Monitor your blood pressure regularly at home and keep a record to share with your doctor during follow-up appointments. This helps your doctor assess how well the medication is working and make any necessary adjustments.
• If you experience bothersome side effects such as dizziness, swelling, or persistent headache, consult your doctor. Do not discontinue AMLOKIND L without their guidance, as abruptly stopping the medication can cause a sudden rise in blood pressure.
• Store AMLOKIND L in a cool, dry place away from direct sunlight and moisture. Keep it out of reach of children and pets to prevent accidental ingestion.

• AMLOKIND L TABLET 10'S does not typically have significant interactions with food. It can be taken with or without food. However, it is generally recommended to maintain a consistent approach (either always with food or always without) to ensure consistent absorption of the medication.
• Grapefruit and grapefruit juice may interact with amlodipine, potentially increasing the levels of the drug in your bloodstream. This could lead to an increased risk of side effects such as low blood pressure, dizziness, and headache. It's best to avoid consuming large quantities of grapefruit or grapefruit juice while taking AMLOKIND L TABLET 10'S.