AMLOZAAR TABLET 10'S

How AMLOZAAR TABLET 10'S Works

• AMLOZAAR TABLET 10'S is a combination medication containing amlodipine and losartan, designed to manage hypertension (high blood pressure) effectively. Amlodipine is a calcium channel blocker, while losartan is an angiotensin II receptor blocker (ARB). Understanding how each component works is crucial to appreciating the overall therapeutic effect of AMLOZAAR.
• Amlodipine functions by inhibiting the entry of calcium ions into vascular smooth muscle cells and cardiac muscle cells. Calcium ions are essential for muscle contraction. By blocking calcium channels, amlodipine causes the smooth muscles in the walls of blood vessels to relax. This relaxation leads to vasodilation, meaning the blood vessels widen. As the blood vessels widen, the resistance to blood flow decreases, resulting in a reduction in blood pressure. Amlodipine primarily affects arterial smooth muscle, which helps lower systolic and diastolic blood pressure.
• Losartan, on the other hand, works through a different mechanism. Angiotensin II is a potent vasoconstrictor, meaning it narrows blood vessels and increases blood pressure. It also stimulates the release of aldosterone, a hormone that causes the kidneys to retain sodium and water, further increasing blood volume and blood pressure. Losartan selectively blocks the binding of angiotensin II to its receptors, particularly the AT1 receptor, found in various tissues including blood vessels and the adrenal gland. By blocking angiotensin II, losartan prevents vasoconstriction and reduces aldosterone release. This leads to vasodilation, reduced sodium and water retention, and consequently, lower blood pressure.
• The synergistic effect of amlodipine and losartan provides a comprehensive approach to blood pressure management. Amlodipine directly relaxes blood vessels, while losartan counteracts the effects of angiotensin II, a key hormone in blood pressure regulation. Together, they offer a more effective and balanced reduction in blood pressure than either medication could achieve alone. This combination helps to reduce the risk of cardiovascular events such as heart attack, stroke, and kidney damage associated with uncontrolled hypertension. The dual mechanism of action ensures that multiple pathways contributing to high blood pressure are addressed, leading to better overall control and improved patient outcomes. It is important to take AMLOZAAR TABLET 10'S exactly as prescribed by your healthcare provider to achieve the best results.
• Furthermore, the combination helps mitigate some of the side effects that might occur if either drug were used alone at higher doses. For instance, amlodipine can sometimes cause peripheral edema (swelling in the ankles and feet), while losartan can affect potassium levels. The combination, when appropriately dosed, can minimize these risks while still providing effective blood pressure control.

Possible side effects of AMLOZAAR TABLET may include: Common side effects: Dizziness, headache, fatigue, edema (swelling) in ankles or feet, flushing (redness of face), palpitations (rapid heartbeat), nausea, abdominal pain, and diarrhea. Uncommon side effects: Insomnia, mood changes, anxiety, depression, tremor, visual disturbances, tinnitus (ringing in the ears), hypotension (low blood pressure), dyspnea (difficulty breathing), vomiting, constipation, dry mouth, skin rash, itching, hair loss, muscle cramps, back pain, increased urination, and impotence. Rare side effects: Confusion, peripheral neuropathy (numbness, tingling in hands and feet), hepatitis (liver inflammation), and allergic reactions.

• If you miss a dose of Amlozaar Tablet 10's, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep AMLOZAAR TAB 1X10 away from the reach of children and pets.
• Store AMLOZAAR TAB 1X10 at room temperature.

• Take Amlozaar Tablet 10'S exactly as prescribed by your doctor. Do not alter the dosage or frequency without consulting your physician, as this medication is designed to manage your condition based on a specific treatment plan. Consistent adherence ensures optimal results.
• Monitor your blood pressure regularly while taking Amlozaar Tablet 10'S. Keep a record of your readings and share them with your doctor during follow-up appointments. This helps in assessing the effectiveness of the medication and making necessary adjustments to your treatment plan.
• Be aware of potential side effects of Amlozaar Tablet 10'S, such as dizziness, swelling, or headache. If you experience any persistent or severe side effects, contact your doctor promptly. Do not drive or operate heavy machinery if you feel dizzy or lightheaded.
• Maintain a healthy lifestyle while taking Amlozaar Tablet 10'S. This includes following a balanced diet low in sodium and saturated fats, engaging in regular physical activity, and avoiding smoking and excessive alcohol consumption. These lifestyle changes can complement the effects of the medication.
• Store Amlozaar Tablet 10'S in a cool, dry place away from direct sunlight and moisture. Keep the medication out of reach of children and pets. Do not use the medication if it has expired or if the packaging is damaged. Always consult your pharmacist or doctor if you have any questions about storage or disposal.

• AMLOZAAR TABLET 10'S can be taken with or without food. However, it is advisable to take it at a fixed time to maintain consistent blood levels. Avoid consuming large amounts of grapefruit or grapefruit juice while taking this medicine, as it can increase the levels of amlodipine in your blood.