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Content Reviewed By:
Dr. Manoj Shah
, (MBBS)
Written By:
Ms. Priyanka Shah
, (B.Pharm)
Like all medicines, AMOXYCLAV 1.2GM INJECTION 10 ML can cause side effects, although not everybody gets them. **Common Side Effects (may affect up to 1 in 10 people):** * Diarrhea * Nausea (feeling sick) * Vomiting * Skin rash **Uncommon Side Effects (may affect up to 1 in 100 people):** * Indigestion * Dizziness * Headache * Urticaria (hives) * Increase in some substances (enzymes) in the blood produced by the liver * Thrush (a yeast infection of the vagina, mouth or skin folds) **Rare Side Effects (may affect up to 1 in 1,000 people):** * Reversible leucopenia (decrease in the number of white blood cells) and thrombocytopenia (decrease in the number of platelets) * Erythema multiforme (red spots that look like small targets with rings around them) **Very Rare Side Effects (may affect up to 1 in 10,000 people):** * Allergic reactions (which can be serious, such as anaphylaxis) * Drug-induced aseptic meningitis * Convulsions (seizures) * Antibiotic-associated colitis * Black hairy tongue * Hepatitis (inflammation of the liver) * Cholestatic jaundice (a condition where bile is trapped in the liver) * Stevens-Johnson syndrome * Toxic epidermal necrolysis * Bullous exfoliative dermatitis * Crystalluria (presence of crystals in urine) **Other Possible Side Effects:** * Flu-like symptoms with a rash, fever, swollen glands, and increased levels of white blood cells (eosinophilia).

Gastrointestinal conditions
Use with cautionAmoxyclav injection can disturb normal gut flora and may cause diarrhea, which is usually mild and self‑limiting.
AMOXYCLAV 1.2GM INJECTION 10 ML is an antibiotic medication used to treat various bacterial infections.
It treats various bacterial infections including pneumonia, bronchitis, sinus infections, urinary tract infections, skin and soft tissue infections, and bone infections.
It is typically administered as an injection into a vein by a healthcare professional.
Common side effects may include nausea, vomiting, diarrhea, and reactions at the injection site.
It's important to consult a doctor before using AMOXYCLAV 1.2GM INJECTION 10 ML during pregnancy.
It's important to consult a doctor before using AMOXYCLAV 1.2GM INJECTION 10 ML during breastfeeding.
AMOXYCLAV 1.2GM INJECTION 10 ML can interact with certain medications, such as warfarin and probenecid. It's important to inform your doctor about all medications you are taking.
Store it at room temperature, away from heat and moisture.
Yes, AMOXYCLAV 1.2GM INJECTION 10 ML can cause allergic reactions in some people. Seek immediate medical attention if you experience symptoms of an allergic reaction such as rash, itching, swelling, or difficulty breathing.
AMOXYCLAV 1.2GM INJECTION 10 ML can be used in children, but the dosage will vary based on the child's weight and the severity of the infection.
It is not recommended to drink alcohol with AMOXYCLAV 1.2GM INJECTION 10 ML, as it may increase the risk of side effects such as nausea, vomiting, and dizziness.
The dosage will vary depending on the severity of the infection and your kidney function. Your doctor will determine the correct dosage for you.
If you miss a dose, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose.
Tell your doctor before taking AMOXYCLAV 1.2GM INJECTION 10 ML if you are allergic to penicillin or cephalosporin antibiotics. Also, tell your doctor if you have kidney disease, liver disease, or mononucleosis.
Yes, AMOXYCLAV 1.2GM INJECTION 10 ML can cause diarrhea. Tell your doctor if you experience severe diarrhea.
Amoxyclav injection is used to treat moderate to severe bacterial infections caused by susceptible organisms. These may include infections of the lower and upper respiratory tract (such as pneumonia and severe bronchitis), urinary tract, skin and soft tissues, bones and joints, intra‑abdominal and pelvic infections, and certain postoperative or hospital‑acquired infections. It is also sometimes used as peri‑operative prophylaxis in selected surgical procedures according to local guidelines. The decision to use this medicine is made by a doctor based on the type and severity of infection and local resistance patterns.
Amoxyclav injection contains two active components: amoxicillin and clavulanic acid. Amoxicillin is a beta‑lactam antibiotic that kills bacteria by inhibiting the synthesis of their cell wall, which is essential for bacterial survival. Some bacteria produce beta‑lactamase enzymes that can break down amoxicillin and make it ineffective. Clavulanic acid inhibits many of these beta‑lactamase enzymes, protecting amoxicillin from degradation and extending its spectrum of activity against beta‑lactamase–producing bacteria. Together, they provide broader and more reliable antibacterial coverage than amoxicillin alone.
Amoxyclav injection is administered only by healthcare professionals, usually in a hospital or clinical setting. It is given either as an intravenous injection, intravenous infusion, or intramuscular injection, depending on the specific product, clinical situation, and local protocols. The powder is reconstituted with an appropriate diluent before administration. The exact dose, frequency, and duration of treatment are determined by the doctor based on the patient’s age, body weight, kidney and liver function, type and severity of infection, and relevant treatment guidelines. Patients should not attempt to self‑inject or adjust their dose.
Common side effects of Amoxyclav injection include pain, redness, or swelling at the injection site, diarrhea, loose stools, nausea, vomiting, abdominal discomfort, and mild skin rash. Some patients may experience headache, dizziness, or mild increases in liver enzymes on blood tests. These effects are often mild and transient. However, if side effects are severe, persistent, or worsening, or if there are signs of an allergic reaction such as rash with itching, swelling of the face or throat, or difficulty breathing, medical attention should be sought immediately.
Yes, Amoxyclav injection can cause allergic reactions, particularly in individuals who are allergic to penicillins, cephalosporins, or other beta‑lactam antibiotics. Reactions may range from mild skin rashes and itching to severe, potentially life‑threatening anaphylaxis. Symptoms of a serious allergic reaction include sudden rash, hives, swelling of the lips, tongue, face, or throat, difficulty breathing, wheezing, and dizziness or fainting. If any of these occur, the injection should be stopped and emergency medical care must be sought immediately. Patients should always inform their doctor about any previous drug allergies before starting treatment.
Amoxyclav injection has been used during pregnancy when clearly needed, and available data do not suggest a high risk of major birth defects. However, as with all medicines, it should be used in pregnancy only if the potential benefit justifies any potential risk to the mother and fetus. The prescribing doctor will carefully assess the severity of the infection, alternative options, and the stage of pregnancy before recommending this medicine. Pregnant patients should not start or stop the injection on their own and should discuss any concerns with their obstetrician or treating physician.
Both amoxicillin and clavulanic acid pass into breast milk in small amounts. In most cases, they are considered compatible with breastfeeding, but there is a possibility of diarrhea, candidiasis (thrush), or rash in the breastfed infant. If Amoxyclav injection is required for the mother, the benefits of treatment are usually considered to outweigh the potential risks, especially for short courses. The infant should be monitored for gastrointestinal disturbances, rash, or signs of allergy. Any unusual symptoms in the baby should be reported to a pediatrician. The decision to continue breastfeeding while on therapy should be made in consultation with the treating doctor.
Yes, patients with impaired kidney or liver function may require dose adjustment or modified dosing intervals of Amoxyclav injection. In kidney impairment, accumulation of the drug can increase the risk of side effects, so the doctor will usually adjust the regimen based on kidney function tests. In liver disease, the medicine should be used with caution because it can occasionally cause liver‑related adverse effects such as cholestatic jaundice or hepatitis. Liver function tests may be monitored during treatment, especially with prolonged use. Patients should never change their dose on their own and must inform their doctor about any known kidney or liver problems before starting therapy.
Before and during treatment with Amoxyclav injection, inform your doctor about any history of allergy to penicillins, cephalosporins, or other medicines; any previous severe skin reactions to antibiotics; and any history of liver disease, kidney disease, or antibiotic‑associated colitis. Provide a complete list of all medicines, supplements, and herbal products you are taking, as some may interact with this antibiotic. Report symptoms such as persistent or severe diarrhea, abdominal cramps, yellowing of the skin or eyes, dark urine, unusual bruising or bleeding, or rash with blisters immediately. Do not skip doses or stop treatment early unless advised by your doctor, even if you feel better.
No, Amoxyclav injection is an antibiotic that is effective only against bacterial infections. It does not work against viruses that cause the common cold, influenza, or most cases of sore throat. Using antibiotics when they are not needed does not improve symptoms, may cause side effects, and contributes to the development of antibiotic resistance. The decision to use Amoxyclav injection should be based on a clinical assessment by a doctor, who may use examination findings and, when appropriate, laboratory tests to determine whether a bacterial infection is present.
Severe, persistent, or bloody diarrhea during or after treatment with Amoxyclav injection may indicate antibiotic‑associated colitis, including Clostridioides difficile–associated diarrhea, which can be serious. If you experience watery or bloody stools, abdominal cramps, or fever, you should contact your doctor immediately. Do not take anti‑diarrheal medicines on your own unless advised by a healthcare professional, as some can worsen the condition. Your doctor will assess the severity, may order tests, and decide whether to stop the antibiotic and start specific treatment for the colitis.
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