ANGICAM H TABLET 15'S

How ANGICAM H TABLET 15'S Works

• ANGICAM H TABLET 15'S is a combination medicine containing Amlodipine and Hydrochlorothiazide. It is primarily used to treat hypertension (high blood pressure). Understanding how each component works is crucial to appreciating the overall effectiveness of this medication.
• **Amlodipine:** Amlodipine belongs to a class of drugs called calcium channel blockers. Calcium channel blockers work by preventing calcium from entering the muscle cells of the heart and blood vessels. This relaxation of the blood vessels allows blood to flow more easily, which lowers blood pressure. Specifically, amlodipine selectively inhibits calcium ion influx across cell membranes, with a greater effect on vascular smooth muscle cells than on cardiac muscle cells. This reduces peripheral vascular resistance, a major determinant of blood pressure. Amlodipine is long-acting, providing sustained blood pressure control over 24 hours with a single daily dose. This helps to reduce the workload on the heart and improves blood flow, reducing the risk of chest pain (angina) and other cardiovascular complications. The drug does not significantly affect heart rate, another major benefit.
• **Hydrochlorothiazide:** Hydrochlorothiazide is a thiazide diuretic, often referred to as a 'water pill.' It works by increasing the excretion of sodium and water from the body through the kidneys. This reduces the volume of blood in the circulation, which in turn lowers blood pressure. Hydrochlorothiazide inhibits the reabsorption of sodium and chloride ions in the distal convoluted tubule of the kidney. By blocking this reabsorption, it promotes the excretion of sodium and water. The diuretic effect also leads to a reduction in extracellular fluid volume, plasma volume, and cardiac output. Over time, hydrochlorothiazide also causes vasodilation, which further contributes to its blood pressure-lowering effects. This diuretic effect also helps reduce edema (swelling) that can occur in people with high blood pressure.
• **Synergistic Action:** The combination of amlodipine and hydrochlorothiazide provides a synergistic effect, meaning that the blood pressure-lowering effect of the two drugs is greater than the sum of their individual effects. Amlodipine's vasodilation complements hydrochlorothiazide's diuretic action, providing comprehensive blood pressure control. The amlodipine helps counteract any fluid retention that might occur because of the hydrochlorothiazide. By using two different mechanisms to lower blood pressure, ANGICAM H TABLET 15'S is effective in a broader range of patients, even those who have not responded adequately to monotherapy (treatment with a single drug). Regular use of this medication, as prescribed by your doctor, is key to managing hypertension and preventing associated health risks such as heart attack, stroke, and kidney damage.

Possible side effects of ANGICAM H Tablet may include: Headache, Dizziness, Fatigue, Nausea, Vomiting, Stomach pain, Diarrhea, Constipation, Flushing (feeling of warmth), Peripheral edema (swelling in the extremities), Palpitations (irregular heartbeat), Hypotension (low blood pressure), Cough, Shortness of breath, Muscle cramps, Increased urination, Changes in liver function tests, Allergic reactions (rash, itching, swelling), Increased risk of bleeding, Elevated blood sugar levels, Electrolyte imbalance, Visual disturbances.

• If you miss a dose of ANGICAM H TABLET, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep ANGICAM H TAB 1X15 away from the reach of children and pets.
• Store ANGICAM H TAB 1X15 at room temperature.

• Take ANGICAM H TABLET 15'S exactly as prescribed by your doctor. Do not alter the dosage or frequency without consulting them. This ensures you receive the optimal benefit from the medication and minimizes potential side effects. Consistent adherence to the prescribed regimen is crucial for managing your condition effectively. If you miss a dose, take it as soon as you remember, unless it's almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
• Inform your doctor about all other medications, supplements, or herbal products you are currently taking before starting ANGICAM H TABLET 15'S. This includes over-the-counter drugs. Some medications can interact with ANGICAM H TABLET 15'S, potentially affecting its effectiveness or increasing the risk of side effects. Your doctor needs a complete picture of your medication profile to make informed decisions about your treatment plan. Be sure to mention any allergies you have to medications or other substances.
• ANGICAM H TABLET 15'S may cause dizziness or lightheadedness, especially when you first start taking it or when the dosage is increased. Avoid driving, operating heavy machinery, or performing other tasks that require alertness until you know how the medication affects you. If dizziness persists or becomes bothersome, consult your doctor. They may recommend strategies to manage this side effect, such as getting up slowly from a sitting or lying position, staying hydrated, or adjusting the dosage.
• Monitor your blood pressure regularly while taking ANGICAM H TABLET 15'S, especially if you are using it to manage hypertension. Keep a record of your blood pressure readings and share them with your doctor during your appointments. This will help your doctor assess the effectiveness of the medication and make any necessary adjustments to your treatment plan. Regular monitoring allows for timely intervention if your blood pressure is not well-controlled.
• Store ANGICAM H TABLET 15'S in a cool, dry place away from direct sunlight and moisture. Keep it out of reach of children and pets. Proper storage ensures the medication remains effective and safe for use. Do not store the medication in the bathroom, as the humidity can affect its stability. Check the expiration date on the packaging and dispose of any expired medication properly. Do not flush medication down the toilet or pour it down the drain, as this can contaminate the water supply.

• ANGICAM H TABLET 15'S generally does not have significant interactions with food. It can be taken with or without food. However, it is advisable to maintain consistency in timing with respect to meals to ensure optimal absorption and effectiveness. If you experience any stomach upset, taking it with food may help.