AZULIX DM 2MG/10MG/500MG TABLET 10'S

How AZULIX DM 2MG/10MG/500MG TABLET 10'S Works

• AZULIX DM 2MG/10MG/500MG TABLET 10'S is a combination medication designed to manage type 2 diabetes effectively. It combines three active ingredients: glimepiride, teneligliptin, and metformin. Each component works through a different mechanism to lower blood glucose levels, providing comprehensive glycemic control.
• Glimepiride, a sulfonylurea, stimulates the pancreas to release more insulin. Insulin is a hormone that helps glucose enter cells, thereby reducing blood sugar levels. It primarily works by binding to specific receptors on pancreatic beta cells, leading to the closure of potassium channels and subsequent depolarization of the cell membrane. This triggers an influx of calcium ions, which promotes the exocytosis of insulin-containing granules.
• Teneligliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor, enhances the incretin system. Incretins are hormones released by the gut in response to food intake. They stimulate insulin release and suppress glucagon secretion, both of which help to lower blood glucose. Teneligliptin works by inhibiting the DPP-4 enzyme, which normally breaks down incretins. By preventing the breakdown of incretins like GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide), teneligliptin prolongs their action, leading to improved insulin secretion and reduced glucagon levels, particularly after meals.
• Metformin, a biguanide, primarily reduces glucose production in the liver and improves insulin sensitivity in peripheral tissues, such as muscles. It also slightly slows down the absorption of glucose from the intestines. Metformin's precise mechanism of action is complex and not fully understood, but it is known to activate AMPK (AMP-activated protein kinase), an enzyme that plays a crucial role in regulating energy balance at the cellular level. Activation of AMPK leads to decreased hepatic glucose production by inhibiting gluconeogenesis (the synthesis of glucose from non-carbohydrate sources) and glycogenolysis (the breakdown of glycogen into glucose). Additionally, metformin enhances insulin sensitivity by increasing the translocation of GLUT4 glucose transporters to the cell membrane in muscle and adipose tissue, facilitating glucose uptake from the bloodstream.
• In summary, AZULIX DM 2MG/10MG/500MG TABLET 10'S works through a triple-pronged approach: glimepiride stimulates insulin release, teneligliptin enhances the incretin system, and metformin reduces hepatic glucose production and improves insulin sensitivity. This combination helps to maintain stable blood glucose levels throughout the day, especially after meals, and provides a more comprehensive approach to managing type 2 diabetes than any single agent could achieve alone. Always use this medication as prescribed by your healthcare provider.

Possible side effects of Azulix DM (Glimepiride, Metformin) may include: * **Hypoglycemia (low blood sugar):** This is a common side effect, especially when combined with other diabetes medications or if meals are skipped. Symptoms include shakiness, sweating, dizziness, confusion, rapid heartbeat, and hunger. * **Gastrointestinal issues:** Nausea, vomiting, diarrhea, abdominal pain, and loss of appetite are common, especially when starting Metformin. These can often be minimized by taking the medication with food and starting with a low dose, gradually increasing as tolerated. * **Lactic acidosis:** This is a rare but serious side effect of Metformin. Symptoms include feeling very weak or tired, unusual muscle pain, trouble breathing, stomach pain with nausea and vomiting, feeling cold, dizziness or lightheadedness, and a slow or irregular heartbeat. Seek immediate medical attention if you experience these symptoms. * **Metallic taste:** Some people experience a metallic taste in their mouth while taking Metformin. * **Skin reactions:** Rash, itching, redness, or hives may occur. * **Headache:** * **Dizziness:** * **Visual disturbances:** * **Weight gain:** Glimepiride can sometimes cause weight gain. * **Liver problems:** In rare cases, liver problems can occur. Symptoms include yellowing of the skin or eyes (jaundice), dark urine, and abdominal pain. * **Decreased Vitamin B12 levels:** Long-term use of Metformin can lead to decreased Vitamin B12 levels. * **Anemia:** * **Agranulocytosis:** * **Thrombocytopenia:** * **Cholestatic Jaundice:** *It is important to note that this is not an exhaustive list, and you should always consult with your doctor or pharmacist if you experience any unusual or bothersome side effects.*

• If you miss a dose of AZULIX DM 2MG/10MG/500MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep AZULIX DM 2/10/500MG TAB 1X10 away from the reach of children and pets.
• Store AZULIX DM 2/10/500MG TAB 1X10 at room temperature.

• Take AZULIX DM 2MG/10MG/500MG TABLET 10'S as prescribed by your doctor, usually once or twice daily with meals. Consistent timing helps maintain stable blood sugar levels.
• Adhere strictly to your diet and exercise plan while taking AZULIX DM. This medication works best when combined with a healthy lifestyle to manage diabetes effectively. Regular physical activity and a balanced diet are crucial.
• Monitor your blood sugar levels regularly, as directed by your healthcare provider. This helps you understand how AZULIX DM 2MG/10MG/500MG TABLET 10'S is working for you and allows for timely adjustments to your treatment plan.
• Be aware of the symptoms of low blood sugar (hypoglycemia), such as sweating, shaking, dizziness, and confusion. Keep a source of fast-acting sugar (e.g., glucose tablets, fruit juice) readily available to treat episodes of low blood sugar promptly. Inform your family and friends about recognizing and treating hypoglycemia.
• Inform your doctor about all other medications, supplements, and herbal products you are taking. Certain drugs can interact with AZULIX DM 2MG/10MG/500MG TABLET 10'S, affecting its efficacy or increasing the risk of side effects. It's essential to provide a complete medication history for safe and effective treatment.
• Stay hydrated by drinking plenty of water throughout the day. Adequate hydration supports overall health and helps your kidneys function properly while taking AZULIX DM.
• If you experience persistent side effects, such as nausea, diarrhea, or abdominal discomfort, consult your doctor. They can provide guidance on managing these effects or adjust your dosage if necessary.
• Attend all scheduled follow-up appointments with your doctor and undergo regular check-ups, including blood tests and kidney function tests. This allows your healthcare provider to monitor your overall health and ensure the medication is working effectively without causing any adverse effects.
• Store AZULIX DM 2MG/10MG/500MG TABLET 10'S at room temperature, away from moisture and direct sunlight. Keep it out of reach of children to prevent accidental ingestion.
• Do not abruptly stop taking AZULIX DM 2MG/10MG/500MG TABLET 10'S without consulting your doctor. Discontinuing the medication suddenly can lead to uncontrolled blood sugar levels and potential health complications. Always follow your doctor's instructions regarding medication use.

• AZULIX DM 2MG/10MG/500MG TABLET 10'S should be taken orally, preferably with or immediately following a meal. This helps to reduce the risk of stomach upset. Consistent timing with meals is recommended for optimal blood sugar control. Avoid excessive alcohol consumption while taking this medication, as it can increase the risk of hypoglycemia (low blood sugar).
• Inform your doctor about your dietary habits, especially if you are on a special diet. This is important for managing your blood sugar levels effectively.