AZULIX SM IR 50/1/1000 TABLET 10'S
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AZULIX SM IR 50/1/1000 TABLET 10'S
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AZULIX SM IR 50/1/1000 TABLET 10'S

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AZULIX SM IR 50/1/1000 TABLET 10'S

By TORRENT PHARMACEUTICALS LIMITED

MRP

153.85

₹130.77

15 % OFF

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About AZULIX SM IR 50/1/1000 TABLET 10'S

  • AZULIX SM IR 50/1/1000 Tablet is a combination medication designed to help adults manage type 2 diabetes. It combines three active ingredients: glimepiride, metformin, and voglibose, each working through different mechanisms to control blood sugar levels effectively.
  • Glimepiride belongs to a class of drugs called sulfonylureas. It stimulates the pancreas to release more insulin, helping to lower blood glucose levels. Metformin, a biguanide, works by decreasing glucose production in the liver and improving insulin sensitivity, allowing the body to use insulin more effectively. Voglibose is an alpha-glucosidase inhibitor that slows down the absorption of carbohydrates from the intestine, preventing rapid spikes in blood sugar after meals.
  • This triple combination therapy is particularly useful for individuals whose blood sugar levels are not adequately controlled with diet, exercise, and other oral antidiabetic medications alone. AZULIX SM IR 50/1/1000 Tablet helps to maintain stable blood sugar levels throughout the day, reducing the risk of diabetes-related complications such as kidney damage, nerve problems, vision loss, and heart disease.
  • It is important to take AZULIX SM IR 50/1/1000 Tablet as prescribed by your doctor, usually once or twice daily with meals. Regular monitoring of blood sugar levels is crucial to ensure the medication is working effectively and to adjust the dosage if needed. Common side effects may include nausea, diarrhea, abdominal pain, and hypoglycemia (low blood sugar). Inform your doctor about any other medications you are taking and any pre-existing medical conditions before starting this medication.
  • AZULIX SM IR 50/1/1000 Tablet is a prescription medication and should only be used under the guidance of a healthcare professional. Always follow your doctor's instructions and seek medical advice if you experience any unusual or severe side effects.

Uses of AZULIX SM IR 50/1/1000 TABLET 10'S

  • Treatment of type 2 diabetes mellitus
  • Controls high blood sugar levels
  • Improves insulin sensitivity
  • Lowers post-meal blood sugar levels
  • Management of insulin resistance in polycystic ovary syndrome (PCOS) (off-label use)

How AZULIX SM IR 50/1/1000 TABLET 10'S Works

  • AZULIX SM IR 50/1/1000 Tablet is a combination medication designed to manage type 2 diabetes mellitus effectively. It combines three active ingredients: Gliclazide, Metformin, and Voglibose, each working through different mechanisms to lower blood glucose levels.
  • Gliclazide, a sulfonylurea, primarily stimulates the pancreas to release more insulin. Insulin is a hormone that helps glucose move from the blood into the body's cells, where it is used for energy. By increasing insulin secretion, Gliclazide helps lower blood sugar levels, especially after meals. It achieves this by binding to specific receptors on pancreatic beta cells, leading to the closure of potassium channels and subsequent influx of calcium ions. This cascade of events triggers the release of insulin from the beta cells.
  • Metformin, a biguanide, works mainly by reducing glucose production in the liver and improving the body's sensitivity to insulin. It inhibits hepatic gluconeogenesis, the process by which the liver produces glucose from non-carbohydrate sources. Additionally, Metformin increases glucose uptake and utilization in peripheral tissues, such as muscles, making them more responsive to insulin's signals. It may also slow down the absorption of glucose from the intestines. Metformin's action on insulin sensitivity helps to lower insulin resistance, a common feature in type 2 diabetes.
  • Voglibose, an alpha-glucosidase inhibitor, delays the absorption of carbohydrates from the small intestine. It works by inhibiting the enzymes (alpha-glucosidases) that break down complex carbohydrates into simpler sugars like glucose. By slowing down carbohydrate digestion, Voglibose reduces the postprandial (after-meal) spike in blood glucose levels. This mechanism is particularly helpful in controlling blood sugar after eating, preventing rapid fluctuations that can be harmful.
  • In summary, AZULIX SM IR 50/1/1000 Tablet provides a comprehensive approach to managing blood sugar by increasing insulin secretion (Gliclazide), reducing glucose production and improving insulin sensitivity (Metformin), and delaying carbohydrate absorption (Voglibose). This triple-action mechanism helps maintain stable blood glucose levels throughout the day, reducing the risk of diabetes-related complications. It is crucial to take this medication as prescribed by your doctor and to follow a healthy diet and exercise plan to maximize its benefits.

Side Effects of AZULIX SM IR 50/1/1000 TABLET 10'SArrow

Common side effects of AZULIX SM IR 50/1/1000 TABLET may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, and hypoglycemia (low blood sugar). Less common but potentially serious side effects include lactic acidosis, allergic reactions (rash, itching, swelling), liver problems (jaundice, dark urine), and blood disorders (anemia, leukopenia, thrombocytopenia). Other possible side effects are headache, dizziness, weakness, constipation, heartburn and blurred vision. This is not an exhaustive list, and it is important to consult with your doctor or pharmacist if you experience any unusual or concerning symptoms while taking this medication.

Safety Advice for AZULIX SM IR 50/1/1000 TABLET 10'SArrow

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Allergies

Allergies

Do not use this medicine if you are allergic to it or any of its ingredients.

Dosage of AZULIX SM IR 50/1/1000 TABLET 10'SArrow

  • The dosage of AZULIX SM IR 50/1/1000 TABLET 10'S is highly individualized and should be determined by your physician based on your specific needs, blood glucose levels, and response to treatment. It is typically taken once or twice daily, preferably with meals to minimize gastrointestinal side effects.
  • The starting dose is usually low, and your doctor may gradually increase it over several weeks to achieve optimal blood glucose control. It's crucial to follow your doctor's instructions carefully and not to adjust the dosage on your own. Self-adjusting the dosage can lead to hypoglycemia (low blood sugar) or hyperglycemia (high blood sugar), both of which can be dangerous.
  • The maximum recommended daily dose depends on individual patient characteristics and the specific formulation. Your doctor will determine the most appropriate dose based on your individual needs and tolerance. Factors such as age, kidney function, and other medical conditions may influence the dosage.
  • It is essential to monitor your blood glucose levels regularly as directed by your doctor. This will help determine if the medication is working effectively and whether any dosage adjustments are needed. Do not skip doses, and take the medication at the same time(s) each day to maintain consistent blood glucose levels.
  • If you miss a dose, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up. Always consult your physician or pharmacist if you have any questions or concerns about your dosage.
  • Take 'AZULIX SM IR 50/1/1000 TABLET 10'S' only as per the prescription by your physician only

What if I miss my dose of AZULIX SM IR 50/1/1000 TABLET 10'S?Arrow

  • If you miss a dose of AZULIX SM IR 50/1/1000 TABLET, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

How to store AZULIX SM IR 50/1/1000 TABLET 10'S?Arrow

  • Keep AZULIX SM 50/1/1000MG TAB 1X10 away from the reach of children and pets.
  • Store AZULIX SM 50/1/1000MG TAB 1X10 at room temperature.

Benefits of AZULIX SM IR 50/1/1000 TABLET 10'SArrow

  • AZULIX SM IR 50/1/1000 TABLET 10'S is a combination medicine specifically formulated to manage type 2 diabetes mellitus effectively. This medication brings together three active ingredients – Gliclazide, Metformin, and Pioglitazone – each playing a crucial role in controlling blood sugar levels through different mechanisms. This comprehensive approach ensures better glycemic control compared to using a single drug.
  • Gliclazide belongs to the sulfonylurea class of drugs. It primarily works by stimulating the pancreas to release more insulin. Insulin is vital as it helps the body's cells absorb glucose from the blood, thereby lowering blood sugar levels. This component is particularly effective in managing post-meal blood sugar spikes, providing a more stable glucose level throughout the day.
  • Metformin is a biguanide and functions by reducing the amount of glucose produced by the liver. It also enhances the body's sensitivity to insulin, allowing cells to use insulin more effectively. This dual action helps lower both fasting and post-meal blood sugar levels. Metformin is often the first-line treatment for type 2 diabetes due to its effectiveness and safety profile.
  • Pioglitazone is a thiazolidinedione (TZD) that improves insulin sensitivity in muscle and fat tissues. It helps the body utilize insulin more efficiently, which lowers blood sugar levels. Pioglitazone also has the benefit of reducing triglycerides and increasing high-density lipoprotein (HDL) cholesterol, contributing to better cardiovascular health.
  • By combining these three medications, AZULIX SM IR offers several advantages. It targets multiple pathways involved in glucose metabolism, resulting in superior blood sugar control. This is particularly beneficial for individuals who haven't achieved adequate control with single or dual therapy. The combination also helps in reducing the risk of long-term complications associated with diabetes, such as cardiovascular disease, nerve damage (neuropathy), kidney damage (nephropathy), and eye damage (retinopathy).
  • Moreover, AZULIX SM IR simplifies the treatment regimen by providing three medications in a single tablet, which can improve adherence and convenience for patients. Improved adherence leads to better blood sugar control and overall health outcomes. This combination is particularly useful for patients who require intensive glucose control to prevent complications and maintain a good quality of life.
  • AZULIX SM IR 50/1/1000 TABLET 10'S is typically prescribed as part of a comprehensive diabetes management plan that includes diet and exercise. It is important to follow your doctor's instructions carefully and monitor blood sugar levels regularly to ensure the medication is working effectively and to adjust the dosage if necessary. Regular check-ups with your healthcare provider are essential to monitor kidney and liver function, as well as to assess for any potential side effects.
  • In summary, AZULIX SM IR 50/1/1000 TABLET 10'S offers a comprehensive and convenient approach to managing type 2 diabetes by combining three effective medications that target different aspects of glucose metabolism. This results in better blood sugar control, reduced risk of long-term complications, and improved adherence to treatment, ultimately enhancing the quality of life for individuals with type 2 diabetes.

How to use AZULIX SM IR 50/1/1000 TABLET 10'SArrow

  • AZULIX SM IR 50/1/1000 Tablet 10'S is a combination medicine used to treat type 2 diabetes mellitus. It is crucial to use this medication as directed by your doctor to manage your blood sugar levels effectively. Typically, it is taken orally, once or twice daily, preferably with meals to minimize the risk of stomach upset.
  • Swallow the tablet whole with a glass of water; do not crush, chew, or break it. Consistency is key, so try to take it at the same time(s) each day to maintain a steady level of medication in your bloodstream. Your doctor will determine the appropriate dosage based on your individual needs and response to treatment. It's important to adhere to this dosage and not exceed it without consulting your healthcare provider.
  • While taking AZULIX SM IR 50/1/1000 Tablet 10'S, it's essential to monitor your blood sugar levels regularly, as directed by your doctor or diabetes educator. This will help you and your doctor track how well the medication is working and make any necessary adjustments to your treatment plan. Lifestyle modifications, such as a healthy diet and regular exercise, are also crucial for managing diabetes effectively and should be followed in conjunction with taking this medication. Inform your doctor about all other medications, supplements, or herbal products you are currently taking, as they may interact with AZULIX SM IR 50/1/1000 Tablet 10'S. If you experience any unusual side effects, such as hypoglycemia (low blood sugar), nausea, or stomach pain, contact your doctor immediately.

Quick Tips for AZULIX SM IR 50/1/1000 TABLET 10'SArrow

  • Take AZULIX SM IR 50/1/1000 exactly as prescribed by your doctor. Do not alter the dosage or stop taking the medication without consulting your healthcare provider. Consistency is key for optimal blood sugar control.
  • It's crucial to take AZULIX SM IR 50/1/1000 with or immediately after a meal. This helps to minimize the risk of stomach upset and ensures better absorption of the medication, maximizing its effectiveness in managing your blood sugar levels.
  • Regularly monitor your blood sugar levels as directed by your doctor while taking AZULIX SM IR 50/1/1000. Keeping a log of your readings will help you and your healthcare provider assess how well the medication is working and make any necessary adjustments to your treatment plan.
  • Inform your doctor about all other medications, supplements, and herbal products you are currently taking. Drug interactions can affect how AZULIX SM IR 50/1/1000 works and potentially lead to unwanted side effects. A complete medication history ensures your safety and the effectiveness of your treatment.
  • Maintain a healthy lifestyle by following a balanced diet and engaging in regular physical activity. These lifestyle modifications, combined with AZULIX SM IR 50/1/1000, can significantly improve your blood sugar control and overall health. Aim for at least 30 minutes of moderate-intensity exercise most days of the week.
  • Be aware of the symptoms of low blood sugar (hypoglycemia), such as sweating, shaking, rapid heartbeat, and confusion. Carry a source of fast-acting sugar, like glucose tablets or fruit juice, with you at all times in case your blood sugar drops too low. Prompt treatment can prevent serious complications.
  • Stay hydrated by drinking plenty of water throughout the day. Adequate hydration is essential for overall health and can help your body process medications more effectively. Dehydration can also affect blood sugar levels, so it's important to maintain proper fluid intake.
  • Attend all scheduled follow-up appointments with your doctor and other healthcare providers. Regular check-ups allow your doctor to monitor your progress, assess for any potential side effects, and make any necessary adjustments to your medication or treatment plan. These appointments are crucial for long-term diabetes management.

Food Interactions with AZULIX SM IR 50/1/1000 TABLET 10'SArrow

  • AZULIX SM IR 50/1/1000 TABLET 10'S should be taken orally, preferably with or immediately following a meal to minimize the risk of gastrointestinal side effects. Consistent timing with meals each day is recommended.
  • Avoid excessive alcohol consumption while taking this medication, as it can increase the risk of hypoglycemia (low blood sugar) and other adverse effects.

FAQs

What is AZULIX SM IR 50/1/1000 TABLET used for?Arrow

AZULIX SM IR 50/1/1000 TABLET is used to treat type 2 diabetes mellitus when diet and exercise alone are not enough to control blood sugar levels.

What are the active ingredients in AZULIX SM IR 50/1/1000 TABLET?Arrow

AZULIX SM IR 50/1/1000 TABLET contains Glimepiride, Metformin, and Sitagliptin as active ingredients.

Are there any common side effects of AZULIX SM IR 50/1/1000 TABLET?Arrow

Common side effects of AZULIX SM IR 50/1/1000 TABLET may include nausea, vomiting, diarrhea, abdominal pain, and headache. Consult a doctor if side effects persist or become severe.

How should I store AZULIX SM IR 50/1/1000 TABLET?Arrow

Store AZULIX SM IR 50/1/1000 TABLET at room temperature, away from direct sunlight and moisture. Keep it out of reach of children and pets.

Should AZULIX SM IR 50/1/1000 TABLET be taken with food?Arrow

AZULIX SM IR 50/1/1000 TABLET is generally recommended to be taken with or immediately after food to minimize the possibility of stomach upset.

What happens if I miss a dose of AZULIX SM IR 50/1/1000 TABLET?Arrow

If you miss a dose of AZULIX SM IR 50/1/1000 TABLET, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Can AZULIX SM IR 50/1/1000 TABLET interact with other medications?Arrow

Yes, AZULIX SM IR 50/1/1000 TABLET can interact with certain medications. Inform your doctor about all the medications, supplements, and herbal products you are taking.

Is AZULIX SM IR 50/1/1000 TABLET safe during pregnancy?Arrow

The safety of AZULIX SM IR 50/1/1000 TABLET during pregnancy has not been established. Consult your doctor if you are pregnant or planning to become pregnant.

Is AZULIX SM IR 50/1/1000 TABLET safe during breastfeeding?Arrow

It is not known whether AZULIX SM IR 50/1/1000 TABLET is excreted in breast milk. Consult your doctor before breastfeeding.

What are the symptoms of an overdose of AZULIX SM IR 50/1/1000 TABLET?Arrow

Symptoms of an overdose of AZULIX SM IR 50/1/1000 TABLET may include hypoglycemia (low blood sugar), nausea, vomiting, and abdominal pain. Seek immediate medical attention if you suspect an overdose.

Can AZULIX SM IR 50/1/1000 TABLET cause dizziness?Arrow

Yes, AZULIX SM IR 50/1/1000 TABLET can cause dizziness in some patients. Avoid driving or operating machinery if you feel dizzy.

Is AZULIX SM IR 50/1/1000 TABLET safe for patients with kidney disease?Arrow

AZULIX SM IR 50/1/1000 TABLET should be used with caution in patients with kidney disease. Your doctor may adjust the dosage based on your kidney function.

Can AZULIX SM IR 50/1/1000 TABLET cause weight gain?Arrow

AZULIX SM IR 50/1/1000 TABLET can cause weight gain in some patients. Monitor your weight and report any significant changes to your doctor.

How long does it take for AZULIX SM IR 50/1/1000 TABLET to start working?Arrow

It may take a few weeks for AZULIX SM IR 50/1/1000 TABLET to start lowering blood sugar levels. It is important to monitor your blood sugar levels regularly and follow your doctor's instructions.

Can AZULIX SM IR 50/1/1000 TABLET be taken with other diabetes medications?Arrow

AZULIX SM IR 50/1/1000 TABLET can be taken with other diabetes medications, but only under the guidance of your doctor. They may adjust the dosage based on your specific needs.

References

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DrugBank: Metformin hydrochloride and glimepiride combination product. This entry provides chemical structures, mechanisms of action, and therapeutic indications for Metformin and Glimepiride.

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FDA Label: Amaryl (glimepiride) tablets prescribing information. Provides details on Glimepiride's clinical pharmacology, indications, dosages, and warnings.

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National Institutes of Health (NIH): Glimepiride versus other insulin secretagogues for type 2 diabetes mellitus: a systematic review and meta-analysis. Discusses the efficacy and safety profile of Glimepiride compared to other similar drugs.

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National Institutes of Health (NIH): Sustained release metformin improves glycemic control in patients with type 2 diabetes mellitus. Studies the benefit of sustained release Metformin in type 2 diabetes.

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European Medicines Agency (EMA): Glimepiride. Provides regulatory information and scientific assessment reports on Glimepiride.

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ScienceDirect: Glimepiride. Provides an overview of Glimepiride, its mechanism of action, pharmacokinetics, and clinical applications.

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Marketer / Manufacturer Details

TORRENT PHARMACEUTICALS LIMITED

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AZULIX SM IR 50/1/1000 TABLET 10'S

AZULIX SM IR 50/1/1000 TABLET 10'S

MRP

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₹130.77

15 % OFF

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