SITAMAX GM 1 FORTE TABLET 10'S

How SITAMAX GM 1 FORTE TABLET 10'S Works

• SITAMAX GM 1 FORTE is a combination medication designed to manage blood sugar levels in individuals with type 2 diabetes. It combines the power of three active ingredients: Sitagliptin, Gliclazide, and Metformin, each working through different mechanisms to achieve optimal glycemic control.
• Sitagliptin belongs to a class of drugs called DPP-4 inhibitors (dipeptidyl peptidase-4 inhibitors). DPP-4 is an enzyme that inactivates incretin hormones. Incretin hormones, such as GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide), are released by the intestine in response to food intake. These hormones stimulate insulin release from the pancreas and decrease glucagon secretion from the liver, both of which help lower blood sugar levels. By inhibiting DPP-4, Sitagliptin increases the levels of active incretin hormones in the body, thereby enhancing insulin secretion and reducing glucagon secretion in a glucose-dependent manner. This means it works when blood sugar is high and has a lower risk of causing hypoglycemia (low blood sugar) compared to some other diabetes medications.
• Gliclazide is a sulfonylurea, a class of drugs that directly stimulates the pancreas to release more insulin. It works by binding to specific receptors on the pancreatic beta cells, which triggers a cascade of events leading to the release of insulin. Gliclazide is effective in lowering blood sugar levels, especially in individuals whose pancreas still has some capacity to produce insulin. However, it is important to note that sulfonylureas like Gliclazide can cause hypoglycemia, especially if meals are skipped or delayed.
• Metformin is a biguanide, and it works primarily by reducing glucose production in the liver. The liver is a major source of glucose in the body, and in individuals with type 2 diabetes, the liver often produces too much glucose. Metformin inhibits hepatic glucose production by activating an enzyme called AMPK (AMP-activated protein kinase). Additionally, Metformin improves insulin sensitivity in peripheral tissues, such as muscles, allowing them to utilize glucose more effectively. It also modestly slows down the absorption of glucose from the intestine. Unlike sulfonylureas, Metformin does not directly stimulate insulin release and therefore carries a lower risk of hypoglycemia when used alone.
• In essence, SITAMAX GM 1 FORTE leverages the complementary actions of Sitagliptin, Gliclazide, and Metformin to provide comprehensive blood sugar control. Sitagliptin enhances incretin hormone activity, Gliclazide stimulates insulin release, and Metformin reduces hepatic glucose production and improves insulin sensitivity. This triple-action approach can lead to better glycemic control compared to using any of these medications alone. However, it's crucial to use this medication under the guidance of a healthcare professional, as it may not be suitable for everyone and requires careful monitoring of blood sugar levels and potential side effects.

Possible side effects of SITAMAX GM 1 FORTE TABLET may include: Common: Nausea, Vomiting, Diarrhea, Abdominal pain, Loss of appetite, Metallic taste. Less Common: Headache, Dizziness, Hypoglycemia (low blood sugar), Skin rash, Itching, Urticaria, Edema. Rare: Liver problems, Changes in blood counts, Allergic reactions. This is not an exhaustive list. Consult your doctor if you experience any unusual symptoms.

• If you miss a dose of SITAMAX GM 1 FORTE TABLET, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep SITAMAX GM 1 FORTE TAB 1X10 away from the reach of children and pets.
• Store SITAMAX GM 1 FORTE TAB 1X10 at room temperature.

• **Take SITAMAX GM 1 FORTE TABLET 10'S as prescribed by your doctor.** Adhere strictly to the dosage and duration advised. Do not self-medicate or alter the dosage without consulting your healthcare provider to maintain stable blood sugar levels and avoid potential complications. This ensures the medication works effectively and safely for you.
• **Administer the medicine before meals**: Take SITAMAX GM 1 FORTE TABLET 10'S before your main meals (breakfast, lunch, dinner). This helps the medicine to work in sync with your body's natural insulin response to food intake. Consistent timing enhances its glucose-lowering effect and minimizes the risk of hypoglycemia, ensuring better control over your diabetes.
• **Monitor your blood sugar regularly:** While taking SITAMAX GM 1 FORTE TABLET 10'S, diligently monitor your blood sugar levels as instructed by your doctor. Keep a record of your readings to share with them during appointments. Regular monitoring is crucial to assess the medication's effectiveness and make necessary adjustments to your treatment plan for optimal blood sugar control.
• **Be aware of Hypoglycemia (low blood sugar) symptoms:** Learn to recognize the signs of hypoglycemia, such as shakiness, sweating, dizziness, and confusion. Always carry a source of fast-acting sugar like glucose tablets or fruit juice with you. If you experience these symptoms, consume the sugar source immediately and inform your doctor, as dosage adjustments may be needed. This proactive approach helps prevent and manage hypoglycemic episodes effectively.
• **Maintain a healthy lifestyle:** Optimize the benefits of SITAMAX GM 1 FORTE TABLET 10'S by adopting a healthy lifestyle. Follow a balanced diet, engage in regular physical activity, and manage stress effectively. These lifestyle modifications complement the medication's effects, leading to improved blood sugar control, overall health, and a reduced risk of diabetes-related complications. Always consult your healthcare provider before making significant changes to your diet or exercise routine.