BIGGABA NT 10/75MG TABLET 10'S
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BIGGABA NT 10/75MG TABLET 10'S
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BIGGABA NT 10/75MG TABLET 10'S

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BIGGABA NT 10/75MG TABLET 10'S

By MANKIND PHARMA LIMITED

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197.89

₹168.21

15 % OFF

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About BIGGABA NT 10/75MG TABLET 10'S

  • BIGGABA NT 10/75MG TABLET is a combination medicine used to treat neuropathic pain. Neuropathic pain is caused by damage to the nerves. This results in abnormal signals being sent to the brain, leading to chronic, often debilitating pain. BIGGABA NT contains two active ingredients: Nortriptyline and Gabapentin. Gabapentin is an anticonvulsant that works by modulating calcium channels in the nerve cells, reducing the release of neurotransmitters that send pain signals. Nortriptyline is a tricyclic antidepressant that increases the levels of chemical messengers (serotonin and norepinephrine) in the brain that stop the movement of pain signals.
  • BIGGABA NT 10/75MG TABLET is effective in relieving neuropathic pain associated with diabetic neuropathy, post-herpetic neuralgia (shingles), and other nerve-related conditions. By targeting different pathways involved in pain transmission, BIGGABA NT provides comprehensive pain relief. It's crucial to use this medication under the guidance of a healthcare professional, as dosage and duration will depend on the individual's condition and response to treatment. Common side effects may include drowsiness, dry mouth, blurred vision, constipation, and weight gain. Patients should report any persistent or bothersome side effects to their doctor.
  • This medication is usually taken orally, with or without food, as directed by your doctor. It's important to take BIGGABA NT at the same time each day to maintain a consistent level of medication in your body. Do not stop taking this medication abruptly, as this may lead to withdrawal symptoms. Your doctor will gradually reduce the dose before stopping it completely. Before starting BIGGABA NT, inform your doctor about any pre-existing medical conditions, especially heart problems, liver problems, kidney problems, or mental health disorders. Also, disclose all other medications you are currently taking, including over-the-counter drugs and herbal supplements, to avoid potential drug interactions. BIGGABA NT offers a valuable option for managing neuropathic pain and improving the quality of life for individuals suffering from this chronic condition.

Uses of BIGGABA NT 10/75MG TABLET 10'S

  • Treatment of Peripheral Neuropathic Pain
  • Treatment of Fibromyalgia
  • Treatment of Post-Herpetic Neuralgia
  • Treatment of Diabetic Neuropathy
  • Treatment of Neuropathic Pain due to Spinal Cord Injury

How BIGGABA NT 10/75MG TABLET 10'S Works

  • BIGGABA NT 10/75MG TABLET 10'S is a combination medication containing Nortriptyline and Gabapentin, designed to manage neuropathic pain. Neuropathic pain arises from nerve damage or dysfunction, leading to abnormal pain signals. This medication works through complementary mechanisms to alleviate this type of pain.
  • Gabapentin, an anticonvulsant, plays a crucial role in reducing the intensity of pain signals transmitted by the nerves. It primarily acts by binding to the α2δ subunit of voltage-gated calcium channels in the central nervous system. By binding to this subunit, gabapentin modulates the influx of calcium ions into nerve terminals. This modulation subsequently reduces the release of excitatory neurotransmitters, such as glutamate, which are involved in the transmission of pain signals. Essentially, Gabapentin calms down the overactive nerves that are sending pain signals.
  • Nortriptyline, a tricyclic antidepressant (TCA), enhances the effects of gabapentin by addressing the emotional and psychological components of chronic pain. It primarily functions by inhibiting the reuptake of neurotransmitters like serotonin and norepinephrine in the brain. By blocking the reuptake, nortriptyline increases the concentration of these neurotransmitters in the synaptic cleft, the space between nerve cells. Elevated levels of serotonin and norepinephrine can improve mood, reduce anxiety, and promote a sense of well-being, which is particularly beneficial for individuals experiencing chronic pain conditions. Nortriptyline also has some analgesic properties of its own, independent of its antidepressant effects. It can help modulate pain pathways and reduce the perception of pain.
  • The synergistic action of Gabapentin and Nortriptyline results in comprehensive pain management. Gabapentin directly targets the nerve signals, reducing the intensity of pain, while Nortriptyline addresses the emotional and psychological aspects, improving overall well-being and contributing to pain relief. The combined effect allows for a more effective and holistic approach to managing neuropathic pain, improving the patient's quality of life. It is essential to take this medication as prescribed by your doctor to achieve optimal results and minimize potential side effects.

Side Effects of BIGGABA NT 10/75MG TABLET 10'SArrow

Common side effects of BIGGABA NT may include: Dizziness, sleepiness, headache, fatigue, uncoordinated body movements, blurred vision, dry mouth, difficulty in passing urine, constipation, increased appetite, weight gain, swelling of extremities, orthostatic hypotension (sudden lowering of blood pressure on standing), memory impairment, difficulty in concentration, irritability, confusion, tremor, and peripheral neuropathy. Uncommon side effects may include: Changes in mood or behavior, anxiety, depression, suicidal thoughts, muscle pain or weakness, sexual dysfunction, decreased libido, visual disturbances, gastrointestinal disturbances (nausea, vomiting, diarrhea), skin rash, itching, and allergic reactions.

Safety Advice for BIGGABA NT 10/75MG TABLET 10'SArrow

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Allergies

Caution

Use with caution if you are allergic to BIGGABA NT 10/75MG TABLET 10'S.

Dosage of BIGGABA NT 10/75MG TABLET 10'SArrow

  • The recommended dosage of 'BIGGABA NT 10/75MG TABLET 10'S' varies significantly depending on individual patient factors, including the severity of neuropathic pain or anxiety, kidney function, other existing medical conditions, and response to treatment. It's crucial to adhere strictly to your physician's prescribed dosage and schedule. Self-adjusting the dosage can lead to adverse effects or reduced effectiveness.
  • Typically, treatment begins with a low dose, which is gradually increased over several weeks to minimize side effects and find the most effective dose. For example, a common starting dose might be one tablet at night, with increases every 3-7 days as tolerated. The dosage increases should be done under strict medical supervision.
  • The maintenance dose will depend on the patient's response. If the pain or anxiety reduces, then your physician will ask you to continue with this dosage or can even reduce it further to the minimum effective dose.
  • If you have kidney problems, your doctor may need to adjust your dose. It's vital to inform your doctor about any kidney-related conditions before starting 'BIGGABA NT 10/75MG TABLET 10'S'.
  • If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.
  • Sudden discontinuation of 'BIGGABA NT 10/75MG TABLET 10'S' can lead to withdrawal symptoms. Always consult your doctor before stopping the medication; they will guide you on how to gradually reduce the dosage to minimize any potential discomfort. Take 'BIGGABA NT 10/75MG TABLET 10'S' only as per the prescription by your physician only

What if I miss my dose of BIGGABA NT 10/75MG TABLET 10'S?Arrow

  • If you miss a dose of BIGGABA NT 10/75MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double the dose to catch up.

How to store BIGGABA NT 10/75MG TABLET 10'S?Arrow

  • Keep BIGGABA NT 10/75MG TAB 1X10 away from the reach of children and pets.
  • Store BIGGABA NT 10/75MG TAB 1X10 at room temperature.

Benefits of BIGGABA NT 10/75MG TABLET 10'SArrow

  • BIGGABA NT 10/75MG TABLET 10'S is a combination medicine used to treat neuropathic pain. Neuropathic pain is a chronic pain condition that arises from nerve damage or dysfunction. It's different from the pain caused by injuries like cuts or breaks because it originates from the nervous system itself. This medication works by modulating nerve signals in the brain, thereby reducing pain sensations.
  • The primary benefit of BIGGABA NT 10/75MG TABLET 10'S is its ability to alleviate neuropathic pain, significantly improving the quality of life for individuals suffering from conditions such as diabetic neuropathy (nerve damage due to diabetes), postherpetic neuralgia (nerve pain after shingles), and other nerve-related pain syndromes. By reducing the intensity of pain, it enables patients to engage in daily activities with greater ease and comfort.
  • This medication contains two active ingredients: Pregabalin and Nortriptyline. Pregabalin is an anticonvulsant and analgesic. It works by binding to certain sites on nerve cells in the spinal cord and brain, which reduces the release of neurotransmitters that transmit pain signals. Nortriptyline is a tricyclic antidepressant. It works by increasing the levels of certain chemical messengers (serotonin and norepinephrine) in the brain that help regulate mood and pain pathways.
  • The combination of these two drugs provides a synergistic effect, meaning that they work together to provide more effective pain relief than either drug could achieve alone. This synergistic effect is particularly beneficial for patients who have not found adequate relief from pain with other medications.
  • BIGGABA NT 10/75MG TABLET 10'S helps in relieving associated symptoms like burning, shooting, stabbing pain and numbness, which often accompany neuropathic pain, offering more comprehensive relief. It also aids in improving sleep disturbances caused by chronic pain. By alleviating pain, patients often experience better sleep quality, contributing to overall well-being.
  • Moreover, BIGGABA NT 10/75MG TABLET 10'S can lead to improved mood and reduced anxiety in some patients with neuropathic pain. Chronic pain can often lead to or exacerbate mood disorders, and by reducing pain, this medication can indirectly improve mental health. However, it is essential to note that the antidepressant component (Nortriptyline) may take several weeks to exert its full effect on mood.
  • BIGGABA NT 10/75MG TABLET 10'S can provide a valuable therapeutic option for individuals struggling with neuropathic pain and its related symptoms. However, it's crucial to use this medication under the guidance of a healthcare professional. They can assess individual patient needs, monitor for potential side effects, and adjust the dosage as necessary to optimize treatment outcomes. Regular follow-up appointments are essential to ensure the safe and effective use of this medication.

How to use BIGGABA NT 10/75MG TABLET 10'SArrow

  • BIGGABA NT 10/75MG TABLET 10'S should be taken orally, exactly as prescribed by your doctor. It is typically prescribed to manage neuropathic pain and certain types of seizures. Do not crush, chew, or break the tablet; swallow it whole with a full glass of water. This helps ensure that the medication is released properly and absorbed effectively.
  • The dosage and frequency of BIGGABA NT 10/75MG TABLET 10'S will depend on your individual medical condition and response to treatment. Your doctor will determine the appropriate dose for you. It is crucial to follow their instructions precisely and not to adjust the dosage yourself, even if you feel better or worse. Taking more than the prescribed dose can increase the risk of side effects, while taking less may not provide adequate relief.
  • Consistency is key to the effectiveness of BIGGABA NT 10/75MG TABLET 10'S. Try to take the medicine at the same time each day to maintain a steady level of the medication in your bloodstream. This will help to control your symptoms more effectively. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for a missed one.
  • It's important to discuss any other medications, supplements, or herbal remedies you are taking with your doctor before starting BIGGABA NT 10/75MG TABLET 10'S. Certain substances can interact with this medication, potentially affecting its effectiveness or increasing the risk of side effects. Alcohol should be avoided while taking this medicine, as it can worsen side effects such as drowsiness and dizziness.
  • Do not stop taking BIGGABA NT 10/75MG TABLET 10'S suddenly without consulting your doctor. Abruptly discontinuing the medication can lead to withdrawal symptoms or a worsening of your condition. Your doctor will gradually reduce the dosage over time to minimize these risks. Regular follow-up appointments with your doctor are essential to monitor your progress and adjust your treatment plan as needed.

Quick Tips for BIGGABA NT 10/75MG TABLET 10'SArrow

  • Take BIGGABA NT 10/75MG TABLET 10'S exactly as prescribed by your doctor. Do not alter the dosage or frequency without consulting them, as this medication affects nerve function and requires careful management.
  • Be consistent with your dosing schedule. Taking BIGGABA NT 10/75MG TABLET 10'S at the same time each day helps maintain a steady level of medication in your body, maximizing its effectiveness in managing nerve pain and improving your overall well-being. Missing doses can lead to a return of symptoms.
  • Inform your doctor about all other medications, supplements, and herbal remedies you are currently taking. BIGGABA NT 10/75MG TABLET 10'S can interact with other substances, potentially reducing its effectiveness or increasing the risk of side effects. This includes over-the-counter medications and even certain foods.
  • Be aware of potential side effects and discuss them with your doctor. Common side effects may include drowsiness, dizziness, dry mouth, and blurred vision. Avoid activities requiring alertness, such as driving or operating heavy machinery, until you know how BIGGABA NT 10/75MG TABLET 10'S affects you. Report any severe or persistent side effects immediately.
  • Store BIGGABA NT 10/75MG TABLET 10'S in a safe place, away from direct sunlight, heat, and moisture. Keep it out of reach of children and pets. Proper storage helps maintain the medication's potency and prevents accidental ingestion. Also, it's important to safely dispose of any unused medication as per guidelines from your pharmacy or healthcare provider.
  • If you experience any improvement in your symptoms, do not stop taking BIGGABA NT 10/75MG TABLET 10'S abruptly without consulting your doctor. Sudden discontinuation can lead to withdrawal symptoms or a worsening of your condition. Your doctor will gradually reduce the dosage if necessary.
  • Maintain a healthy lifestyle to complement the effects of BIGGABA NT 10/75MG TABLET 10'S. This includes eating a balanced diet, engaging in regular exercise, and managing stress levels. These lifestyle factors can positively impact nerve health and contribute to overall pain management. Talk to your healthcare provider or a registered dietitian for more tailored guidance.

Food Interactions with BIGGABA NT 10/75MG TABLET 10'SArrow

  • BIGGABA NT 10/75MG TABLET 10'S can be taken with or without food, but it's best to take it at a consistent time each day to help you remember. Avoid alcohol while taking this medicine as it can increase drowsiness and other side effects.
  • Taking BIGGABA NT 10/75MG TABLET 10'S with food might help reduce stomach upset. However, the absorption of the medicine might be affected slightly depending on the type of food consumed. Consult your doctor or pharmacist for personalized advice regarding food interactions.

FAQs

What is BIGGABA NT 10/75MG TABLET 10'S used for?Arrow

BIGGABA NT 10/75MG TABLET 10'S is primarily used to treat peripheral neuropathic pain, which is pain caused by nerve damage due to conditions like diabetes or shingles.

How does BIGGABA NT 10/75MG TABLET 10'S work?Arrow

This medication works as a combination of Gabapentin and Nortriptyline. Gabapentin helps reduce pain signals, while Nortriptyline helps in reducing nerve pain.

What are the common side effects of BIGGABA NT 10/75MG TABLET 10'S?Arrow

Common side effects may include dizziness, sleepiness, dry mouth, constipation, and weight gain.

Is BIGGABA NT 10/75MG TABLET 10'S habit-forming?Arrow

This medication is not habit-forming, but it should only be taken as per the dosage and duration prescribed by the doctor.

Can BIGGABA NT 10/75MG TABLET 10'S be taken with or without food?Arrow

It can be taken with or without food, but it is better to take it with food to avoid stomach upset.

Should BIGGABA NT 10/75MG TABLET 10'S be stopped abruptly?Arrow

No, this medication should not be stopped abruptly. The dosage should be reduced gradually, as directed by the doctor.

Is BIGGABA NT 10/75MG TABLET 10'S safe for pregnant women?Arrow

This medication should only be used during pregnancy if clearly needed and prescribed by the doctor. It is important to discuss the risks and benefits.

Is BIGGABA NT 10/75MG TABLET 10'S safe for breastfeeding women?Arrow

Breastfeeding women should consult a doctor before using this medication, as it may pass into breast milk and affect the infant.

What are the symptoms of an overdose of BIGGABA NT 10/75MG TABLET 10'S?Arrow

Symptoms of an overdose may include extreme sleepiness, confusion, blurred vision, difficulty speaking, and trouble breathing.

Can BIGGABA NT 10/75MG TABLET 10'S interact with other medications?Arrow

Yes, this medication can interact with certain other medications, such as opioid pain relievers, antidepressants, and antihistamines. It is important to inform the doctor about all medications being taken.

How should BIGGABA NT 10/75MG TABLET 10'S be stored?Arrow

This medication should be stored at room temperature, away from direct sunlight and moisture. Keep it out of reach of children.

What should I do if I miss a dose of BIGGABA NT 10/75MG TABLET 10'S?Arrow

If you miss a dose, take it as soon as possible. If it is almost time for the next dose, skip the missed dose and continue with your regular schedule.

Is it safe to drink alcohol while taking BIGGABA NT 10/75MG TABLET 10'S?Arrow

Drinking alcohol while taking BIGGABA NT 10/75MG TABLET 10'S can increase side effects such as dizziness and sleepiness, so it should be avoided.

What other brands of Gabapentin are available?Arrow

Gabapentin is available under various brand names such as Gabica, Neurontin, and Pentagaba.

Can BIGGABA NT 10/75MG TABLET 10'S cause weight gain?Arrow

Yes, BIGGABA NT 10/75MG TABLET 10'S can cause weight gain in some people. Consult a doctor if this is a concern.

References

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Pregabalin: A Review of Its Pharmacology and Use in the Treatment of Neuropathic Pain

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Pregabalin DrugBank Online

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FDA Label for Pregabalin

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Nortriptyline - StatPearls - NCBI Bookshelf

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Nortriptyline DrugBank Online

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FDA Label for Nortriptyline

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MANKIND PHARMA LIMITED

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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