CARDACE AM 5MG TABLET 15'S

How CARDACE AM 5MG TABLET 15'S Works

• CARDACE AM 5MG TABLET 15'S is a combination medication containing two active ingredients: Ramipril and Amlodipine. These components work synergistically to effectively manage high blood pressure (hypertension) and reduce the risk of cardiovascular events such as heart attack and stroke. Understanding how each ingredient functions is crucial to appreciating the overall therapeutic effect of CARDACE AM.
• Ramipril belongs to a class of drugs called angiotensin-converting enzyme (ACE) inhibitors. ACE is an enzyme in the body that converts angiotensin I to angiotensin II. Angiotensin II is a potent vasoconstrictor, meaning it narrows blood vessels, increasing blood pressure. Ramipril inhibits ACE, thus reducing the production of angiotensin II. This leads to vasodilation (widening of blood vessels), which lowers blood pressure. By decreasing angiotensin II levels, Ramipril also reduces the release of aldosterone, a hormone that causes the kidneys to retain sodium and water. This further contributes to lowering blood volume and blood pressure. In addition to its blood pressure-lowering effects, Ramipril has cardioprotective properties. It can help improve blood vessel function, reduce inflammation, and prevent the remodeling of the heart muscle that can occur in response to high blood pressure or heart failure.
• Amlodipine is a calcium channel blocker. It works by blocking the entry of calcium into the smooth muscle cells of blood vessel walls. Calcium is essential for muscle contraction. By blocking calcium influx, Amlodipine causes the smooth muscles to relax, leading to vasodilation. This widening of blood vessels reduces peripheral vascular resistance, the force against which the heart must pump, thereby lowering blood pressure. Amlodipine primarily affects the arteries and has a minimal effect on the veins. It is particularly effective in reducing systolic blood pressure, the top number in a blood pressure reading. Unlike some other blood pressure medications, Amlodipine does not significantly affect heart rate.
• The combination of Ramipril and Amlodipine in CARDACE AM provides a complementary approach to blood pressure management. Ramipril addresses the hormonal component of blood pressure regulation by inhibiting the renin-angiotensin-aldosterone system (RAAS), while Amlodipine directly relaxes blood vessels by blocking calcium channels. This dual mechanism of action often results in more effective blood pressure control than either medication alone. Furthermore, the combination may help to minimize the side effects associated with higher doses of either individual medication. For instance, Ramipril can sometimes cause a dry cough, and Amlodipine can cause ankle swelling. Using a combination allows for lower doses of each, potentially reducing the incidence and severity of these side effects.
• In summary, CARDACE AM 5MG TABLET 15'S works by combining the ACE-inhibiting action of Ramipril with the calcium channel blocking action of Amlodipine. This results in vasodilation, reduced blood volume, and decreased peripheral vascular resistance, leading to effective blood pressure control and a reduced risk of cardiovascular events. It's essential to take this medication as prescribed by your doctor and to follow their recommendations regarding lifestyle modifications, such as diet and exercise, to maximize its benefits.

Common side effects of Cardace AM 5mg Tablet may include: Dizziness, Headache, Fatigue, Sleepiness, Nausea, Abdominal pain, Constipation, Flushing (sense of warmth in the face, ears, neck and trunk), Palpitations, Ankle swelling. Uncommon side effects may include: Cough, Diarrhea, Indigestion, Muscle cramps, Skin rash, Visual disturbances, Joint pain, Chest pain, Back pain, Increased urination, Mood changes, Dry mouth, Hair loss, Impotence (difficulty in achieving or maintaining an erection), Allergic reactions.

• If you miss a dose of CARDACE AM 5MG TABLET 15'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep CARDACE AM 5MG TAB 1X15 away from the reach of children and pets.
• Store CARDACE AM 5MG TAB 1X15 at room temperature.

• Take CARDACE AM 5MG TABLET 15'S exactly as prescribed by your doctor. Do not change the dose or stop taking the medication without consulting your healthcare provider, as this could lead to uncontrolled blood pressure or other complications. Consistency is key for optimal results.
• CARDACE AM 5MG TABLET 15'S can be taken with or without food. However, it's best to take it at the same time each day to help you remember. Maintaining a routine ensures a steady level of medication in your system.
• Inform your doctor about all other medications, supplements, or herbal remedies you are taking. Certain substances can interact with CARDACE AM 5MG TABLET 15'S, affecting its efficacy or increasing the risk of side effects. This includes over-the-counter medications and natural remedies.
• Monitor your blood pressure regularly while taking CARDACE AM 5MG TABLET 15'S, especially during the initial stages of treatment or after dosage adjustments. Keep a record of your readings to share with your doctor during check-ups. This helps assess the medication's effectiveness and adjust the treatment plan if needed.
• Be aware of potential side effects, such as dizziness, lightheadedness, or swelling in the ankles or feet. If these or any other concerning symptoms occur, contact your doctor promptly. Don't hesitate to seek medical advice for any unusual reactions or concerns.
• Lifestyle modifications can significantly enhance the effectiveness of CARDACE AM 5MG TABLET 15'S. Adopt a heart-healthy diet low in sodium and saturated fats, engage in regular physical activity, maintain a healthy weight, and avoid smoking. These changes work synergistically with the medication to improve cardiovascular health.
• Store CARDACE AM 5MG TABLET 15'S at room temperature, away from moisture and direct sunlight. Keep it out of reach of children and pets. Proper storage ensures the medication remains effective and safe for consumption.

• CARDACE AM 5MG TABLET 15'S can be taken with or without food. However, it is advisable to take it at a fixed time to maintain consistent blood levels. Avoid consuming grapefruit or grapefruit juice while taking this medicine, as it may increase the blood levels of amlodipine and potentially enhance its blood pressure-lowering effect, leading to dizziness or other adverse effects. Consult your doctor if you have any concerns.