CILMIKAA TM 50MG TABLET 10'S

How CILMIKAA TM 50MG TABLET 10'S Works

• CILMIKAA TM 50MG TABLET 10'S is a medication primarily used to manage and treat certain types of cancers, particularly advanced renal cell carcinoma (RCC), which is kidney cancer. It contains Temsirolimus as its active ingredient. Temsirolimus belongs to a class of drugs known as mTOR (mammalian target of rapamycin) inhibitors.
• mTOR is a protein kinase that plays a crucial role in cell growth, proliferation, metabolism, and angiogenesis (the formation of new blood vessels). In cancer cells, the mTOR pathway is often overactive, contributing to uncontrolled cell growth and survival. Temsirolimus works by selectively inhibiting mTOR. This inhibition disrupts the signaling pathways that promote cancer cell growth and division.
• By blocking mTOR, Temsirolimus interferes with several key processes essential for cancer progression. First, it reduces the production of proteins involved in cell proliferation, slowing down the rate at which cancer cells multiply. Second, it inhibits angiogenesis, cutting off the blood supply that tumors need to grow and spread. Third, it affects glucose metabolism, depriving cancer cells of the energy they require to thrive.
• Specifically, Temsirolimus binds to an intracellular protein called FKBP12, and the resulting complex then binds to and inhibits the mTOR protein. This action leads to a decrease in the levels of proteins such as HIF-1α (hypoxia-inducible factor 1 alpha) and VEGF (vascular endothelial growth factor), which are involved in angiogenesis and tumor growth. By reducing these factors, Temsirolimus helps to suppress the growth and spread of cancer cells.
• The overall effect of CILMIKAA TM 50MG TABLET 10'S is to slow down the progression of cancer, reduce tumor size, and potentially improve the survival rate in patients with advanced renal cell carcinoma. It is important to note that the drug is usually prescribed as part of a comprehensive treatment plan and under the close supervision of a healthcare professional. Patients should adhere to the prescribed dosage and schedule and report any side effects or concerns to their doctor promptly.

Possible side effects of CILMIKAA TM 50MG TABLET 10'S may include: * **Common:** Nausea, vomiting, diarrhea, headache, dizziness, fatigue, abdominal pain, loss of appetite, skin rash, itching. * **Uncommon:** Insomnia, anxiety, depression, blurred vision, changes in taste, muscle weakness, joint pain, hair loss, liver problems (e.g., jaundice), allergic reactions (e.g., swelling, difficulty breathing), changes in blood cell counts. * **Rare:** Severe skin reactions (e.g., Stevens-Johnson syndrome), seizures, heart problems (e.g., irregular heartbeat), kidney problems.

• If you miss a dose of CILMIKAA TM 50MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep CILMIKAA TM 50MG TAB 1X10 away from the reach of children and pets.
• Store CILMIKAA TM 50MG TAB 1X10 at room temperature.

• CILMIKAA TM 50MG TABLET 10'S is typically prescribed to manage moderate to severe rheumatoid arthritis in adults who haven't responded well to other treatments. It works by selectively inhibiting Janus kinases (JAKs), enzymes involved in inflammation and immune response.
• Take CILMIKAA TM 50MG TABLET 10'S exactly as your doctor prescribes. The usual dose is 50mg once daily, but your doctor may adjust this based on your response and other medications you're taking. Consistency in taking the medication at the same time each day is important for optimal effectiveness.
• Before starting CILMIKAA TM 50MG TABLET 10'S, inform your doctor about all your medical conditions, especially any history of infections (such as tuberculosis, herpes zoster/shingles, or fungal infections), liver or kidney problems, blood clots, heart problems, cancer, or a weakened immune system. Also, disclose all medications, supplements, and herbal products you are taking.
• CILMIKAA TM 50MG TABLET 10'S can weaken your immune system, increasing your risk of infections. Watch for signs of infection, such as fever, cough, chills, sweating, or painful skin rash, and report them to your doctor immediately. Avoid close contact with people who are sick. Your doctor may recommend certain vaccinations before you start treatment, but avoid live vaccines.
• Common side effects of CILMIKAA TM 50MG TABLET 10'S may include nausea, diarrhea, headache, and upper respiratory tract infections. More serious side effects can include blood clots, changes in blood cell counts, elevated cholesterol levels, and liver problems. Contact your doctor promptly if you experience any concerning symptoms.

• CILMIKAA TM 50MG TABLET 10'S can be taken with or without food. However, taking it with food may reduce the risk of stomach upset. Avoid consuming large amounts of grapefruit or grapefruit juice while taking this medicine, as it may increase the level of the drug in your bloodstream.