CILNY O 20MG TABLET 10'S

How CILNY O 20MG TABLET 10'S Works

• CILNY O 20MG TABLET 10'S is a combination medication designed to effectively manage hypertension (high blood pressure) and related cardiovascular conditions. It brings together the synergistic effects of two active ingredients: Cilnidipine and Olmesartan Medoxomil. Each component plays a distinct role in lowering blood pressure through complementary mechanisms.
• Cilnidipine, a dihydropyridine calcium channel blocker (DHP CCB), primarily targets L-type calcium channels found in arterial smooth muscle cells. These channels are crucial for regulating calcium influx, which triggers muscle contraction and vasoconstriction (narrowing of blood vessels). By selectively blocking these calcium channels, Cilnidipine reduces the entry of calcium into the smooth muscle cells. This relaxation of the arterial walls leads to vasodilation, effectively reducing peripheral vascular resistance and, consequently, lowering blood pressure. Cilnidipine's unique feature is its dual action; it also acts on N-type calcium channels found in sympathetic nerve terminals. By blocking these N-type calcium channels, Cilnidipine inhibits the release of norepinephrine, a neurotransmitter responsible for increasing heart rate and blood pressure. This dual blockade helps to prevent reflex tachycardia (a rapid increase in heart rate) that can sometimes occur with other DHP CCBs, offering a more balanced approach to blood pressure control.
• Olmesartan Medoxomil, on the other hand, is an angiotensin II receptor blocker (ARB). Angiotensin II is a potent vasoconstrictor hormone that plays a key role in the renin-angiotensin-aldosterone system (RAAS), a hormonal system that regulates blood pressure and fluid balance. Angiotensin II binds to AT1 receptors in blood vessels, causing vasoconstriction and increasing blood pressure. It also stimulates the release of aldosterone, which promotes sodium and water retention by the kidneys, further increasing blood volume and blood pressure. Olmesartan Medoxomil works by selectively blocking the AT1 receptors, preventing angiotensin II from binding and exerting its vasoconstrictive and aldosterone-releasing effects. By blocking the action of angiotensin II, Olmesartan Medoxomil promotes vasodilation, reduces sodium and water retention, and ultimately lowers blood pressure.
• The combination of Cilnidipine and Olmesartan Medoxomil in CILNY O 20MG TABLET 10'S provides a comprehensive approach to blood pressure management. Cilnidipine reduces vascular resistance through calcium channel blockade, while Olmesartan Medoxomil blocks the effects of angiotensin II. This dual mechanism addresses different pathways involved in blood pressure regulation, resulting in a more effective and sustained reduction in blood pressure compared to either drug used alone. The reduced likelihood of reflex tachycardia with Cilnidipine further enhances the tolerability and efficacy of the combination.
• In summary, CILNY O 20MG TABLET 10'S works by combining a calcium channel blocker (Cilnidipine) that relaxes blood vessels and an angiotensin II receptor blocker (Olmesartan Medoxomil) that prevents the constricting action of angiotensin II. This dual action helps to lower blood pressure effectively and protect against cardiovascular complications.

Common side effects of CILNY O 20MG TABLET may include headache, dizziness, flushing (feeling of warmth), nausea, vomiting, stomach pain, indigestion, diarrhea, constipation, weakness, swelling of ankles or feet, palpitations, and low blood pressure. Less common but potentially serious side effects include allergic reactions (rash, itching, swelling), chest pain, irregular heartbeat, and changes in liver function. Rarely, CILNY O 20MG TABLET can cause more severe reactions. Consult your doctor immediately if you experience any troublesome or persistent side effects.

• If you miss a dose of CILNY O 20MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

• Keep CILNY O 20MG TAB 1X10 away from the reach of children and pets.
• Store CILNY O 20MG TAB 1X10 at room temperature.

• **Take CILNY O 20MG TABLET 10'S as prescribed:** Always follow your doctor's instructions regarding dosage and timing. Do not adjust the dose yourself without consulting your healthcare provider. Consistency is key for optimal results.
• **Be mindful of potential side effects:** Common side effects may include headache, flushing, dizziness, and ankle swelling. If these side effects are bothersome or persistent, inform your doctor. Serious side effects are rare but require immediate medical attention.
• **CILNY O 20MG TABLET 10'S can be taken with or without food:** While it's not strictly necessary to take this medication with food, doing so might help reduce the chance of stomach upset in some individuals. Choose the method that works best for you and stick to it consistently.
• **Avoid grapefruit and grapefruit juice:** Grapefruit can interact with CILNY O 20MG TABLET 10'S, potentially increasing the drug's levels in your bloodstream and raising the risk of side effects. It's best to avoid grapefruit products while taking this medication.
• **Inform your doctor about all other medications:** Before starting CILNY O 20MG TABLET 10'S, tell your doctor about all other medications you are taking, including prescription drugs, over-the-counter medications, vitamins, and herbal supplements. This will help prevent potential drug interactions.
• **Monitor your blood pressure regularly:** Cilnidipine, the active ingredient in CILNY O 20MG TABLET 10'S, lowers blood pressure. Regular monitoring at home can help you and your doctor assess how well the medication is working and make adjustments if needed. Keep a record of your readings.
• **Stay hydrated:** Drinking plenty of water can help prevent dizziness and other side effects associated with blood pressure medications. Aim for at least eight glasses of water per day, unless your doctor advises otherwise.
• **Avoid alcohol:** Alcohol can lower blood pressure and may increase the risk of side effects such as dizziness and lightheadedness when taken with CILNY O 20MG TABLET 10'S. It's best to avoid alcohol or limit your intake while on this medication.
• **Store CILNY O 20MG TABLET 10'S properly:** Store the medication in a cool, dry place away from direct sunlight and moisture. Keep it out of reach of children and pets. Check the expiration date and discard any expired medication properly.
• **Do not stop taking CILNY O 20MG TABLET 10'S abruptly:** Even if you feel well, continue taking CILNY O 20MG TABLET 10'S as prescribed by your doctor. Suddenly stopping the medication can cause a rapid increase in blood pressure, which can be dangerous. If you need to stop the medication, your doctor will gradually reduce the dose.

• CILNY O 20MG TABLET 10'S can be taken with or without food. However, it is best to take it at a consistent time each day to maintain a steady level of medication in your body.
• Avoid consuming large amounts of grapefruit or grapefruit juice while taking CILNY O 20MG TABLET 10'S, as it may increase the levels of the medication in your blood and potentially increase side effects.
• If you experience any stomach upset, taking the medication with a small meal may help.