CLAVIX AS 150MG TABLET 15'S

How CLAVIX AS 150MG TABLET 15'S Works

• CLAVIX AS 150MG TABLET 15'S is a combination medication designed to prevent blood clots, primarily used in patients at risk of heart attack, stroke, or those with peripheral vascular disease. It combines two active ingredients: Clopidogrel and Aspirin, each working through different mechanisms to achieve this antiplatelet effect.
• Clopidogrel, a thienopyridine derivative, functions as a platelet aggregation inhibitor. Platelets are small blood cells that play a crucial role in forming blood clots. When blood vessels are damaged, platelets are activated and begin to stick together, initiating the clotting process. Clopidogrel inhibits this process by selectively and irreversibly blocking the binding of adenosine diphosphate (ADP) to its platelet P2Y12 receptor. ADP is a chemical signal that promotes platelet activation and aggregation. By blocking this receptor, Clopidogrel prevents ADP from activating platelets, thereby reducing their ability to clump together and form clots. This effect lasts for the lifespan of the platelet (approximately 7-10 days). Because the inhibition is irreversible, the platelet's function is impaired until new platelets are produced.
• Aspirin, also known as acetylsalicylic acid, is a nonsteroidal anti-inflammatory drug (NSAID) that possesses antiplatelet properties. Aspirin inhibits the production of thromboxane A2, a prostaglandin that stimulates platelet aggregation and vasoconstriction. It achieves this by irreversibly acetylating cyclooxygenase-1 (COX-1), an enzyme responsible for synthesizing thromboxane A2. By inhibiting COX-1, Aspirin reduces the production of thromboxane A2, thereby reducing platelet activation and aggregation. The antiplatelet effect of Aspirin is also irreversible, lasting for the lifespan of the platelet.
• The combination of Clopidogrel and Aspirin provides a synergistic antiplatelet effect. Clopidogrel blocks ADP-mediated platelet activation, while Aspirin inhibits thromboxane A2 production. By targeting two different pathways involved in platelet activation, CLAVIX AS 150MG TABLET 15'S provides more effective platelet inhibition than either drug alone. This enhanced antiplatelet activity helps to prevent the formation of dangerous blood clots that can lead to heart attack, stroke, and other cardiovascular events. The 150mg dosage typically refers to the Aspirin component; the Clopidogrel dosage may vary and should be confirmed with the prescribing information.
• In summary, CLAVIX AS 150MG TABLET 15'S works by using Clopidogrel to block ADP-mediated platelet activation and Aspirin to inhibit thromboxane A2 production. This dual mechanism reduces the ability of platelets to clump together, thus preventing the formation of blood clots and reducing the risk of cardiovascular events.

Like all medicines, CLAVIX AS 150MG TABLET 15'S can cause side effects, although not everybody gets them. The most commonly reported side effects are: * Increased bleeding tendency (e.g., nosebleeds, easy bruising) * Gastrointestinal issues (e.g., stomach pain, diarrhea, indigestion, nausea) Less common but potentially serious side effects include: * Severe allergic reactions (e.g., skin rash, itching, swelling of the face, lips, tongue, or throat, difficulty breathing) * Thrombotic Thrombocytopenic Purpura (TTP) – a rare disorder involving blood clots in small blood vessels * Intracranial hemorrhage (bleeding in the brain) * Agranulocytosis (severe reduction in white blood cells, increasing the risk of infection) * Liver problems (e.g., jaundice, hepatitis) * Kidney problems Other possible side effects: * Headache * Dizziness * Skin rashes, eczema, itching * Constipation * Vomiting * Flatulence * Ulcers * Arthralgia (joint pain) * Myalgia (muscle pain) * Fever * Changes in taste This is not an exhaustive list. If you experience any unusual symptoms while taking CLAVIX AS 150MG TABLET 15'S, consult your doctor immediately.

• If you miss a dose of CLAVIX AS 150MG TABLET 15'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

• Keep CLAVIX AS 150MG TAB 1X15 away from the reach of children and pets.
• Store CLAVIX AS 150MG TAB 1X15 at room temperature.

• Take CLAVIX AS 150MG TABLET 15'S exactly as prescribed by your doctor. Do not change the dosage or stop taking it without consulting your healthcare provider. This medication is usually taken once daily, with or without food. Consistent timing helps maintain stable blood levels of the drugs, improving its effectiveness.
• CLAVIX AS 150MG TABLET 15'S contains a combination of antiplatelet medications (aspirin and clopidogrel) which increases your risk of bleeding. Be cautious when performing activities that may cause injury, such as shaving, using sharp objects, or participating in contact sports. Inform your doctor and dentist that you are taking this medicine before any surgery or dental procedure.
• Inform your doctor about all other medications, supplements, and herbal products you are currently taking before starting CLAVIX AS 150MG TABLET 15'S. Certain medications can interact with clopidogrel and aspirin, increasing the risk of side effects or reducing their effectiveness. Especially important are other blood thinners, NSAIDs (like ibuprofen or naproxen), and certain antidepressants.
• Be aware of the potential side effects of CLAVIX AS 150MG TABLET 15'S. Common side effects include bruising, nosebleeds, and prolonged bleeding from cuts. If you experience any unusual or severe bleeding, such as blood in your stool or urine, black or tarry stools, coughing up blood, or severe headaches, seek immediate medical attention.
• Store CLAVIX AS 150MG TABLET 15'S at room temperature, away from moisture and heat. Keep it out of reach of children. If you miss a dose, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up. Adhering to these instructions ensures optimal efficacy and safety.

• Clavix AS 150mg Tablet can be taken with or without food. Food does not significantly affect the absorption of the medication. However, it is advisable to take the tablet at the same time each day to maintain consistent blood levels.