CLOPISTATUS ASP 75/150MG TABLET 15'S

How CLOPISTATUS ASP 75/150MG TABLET 15'S Works

• CLOPISTATUS ASP 75/150MG TABLET 15'S is a combination medication containing Clopidogrel and Aspirin, both of which are antiplatelet agents. This combination is prescribed to prevent blood clots in individuals at high risk of cardiovascular events such as heart attack, stroke, and peripheral artery disease. Understanding how each component works is crucial to appreciating the overall mechanism of action.
• Clopidogrel belongs to a class of drugs called thienopyridines. It works by inhibiting the binding of adenosine diphosphate (ADP) to its platelet receptor, P2Y12. ADP is a chemical messenger that promotes platelet aggregation, the process by which platelets stick together to form blood clots. By blocking ADP from binding, Clopidogrel prevents platelets from becoming activated and clumping together. This reduces the likelihood of a blood clot forming in the arteries, which can block blood flow and lead to serious cardiovascular problems. The effect of Clopidogrel is irreversible, meaning that once a platelet is affected, it remains inhibited for its lifespan (about 7-10 days).
• Aspirin, also known as acetylsalicylic acid (ASA), is a nonsteroidal anti-inflammatory drug (NSAID) with antiplatelet properties. Aspirin inhibits the production of thromboxane A2, a substance that also promotes platelet aggregation and vasoconstriction (narrowing of blood vessels). It achieves this by irreversibly inhibiting cyclooxygenase-1 (COX-1), an enzyme responsible for synthesizing thromboxane A2 in platelets. By suppressing thromboxane A2 production, Aspirin reduces platelet activation and clumping, further contributing to the prevention of blood clot formation. Unlike Clopidogrel, Aspirin affects platelets for their entire lifespan.
• The combination of Clopidogrel and Aspirin provides a dual antiplatelet effect by targeting different pathways involved in platelet activation and aggregation. Clopidogrel blocks the ADP pathway, while Aspirin inhibits the thromboxane A2 pathway. This synergistic action results in a more potent antiplatelet effect compared to either drug alone. This is particularly beneficial in patients at high risk of thrombotic events, such as those with a history of heart attack, stroke, or stent placement. However, because of the increased risk of bleeding, the combination of Clopidogrel and Aspirin is typically reserved for specific clinical situations and should be used under close medical supervision. Your doctor will assess your individual risk factors and determine if this combination therapy is appropriate for you.
• In essence, CLOPISTATUS ASP 75/150MG TABLET 15'S works by making your blood less sticky, reducing the chance of dangerous clots forming in your arteries. This helps to maintain healthy blood flow and reduces the risk of heart attack and stroke. Always take this medication exactly as prescribed by your doctor.

Common side effects of CLOPISTATUS ASP 75/150MG TABLET may include: Increased risk of bleeding (such as nosebleeds, easy bruising), indigestion, abdominal pain, diarrhea. Less common but potentially serious side effects include: Allergic reactions (rash, itching, swelling), severe bleeding (gastrointestinal bleeding, bleeding in the brain), thrombotic thrombocytopenic purpura (TTP - a blood disorder), and liver problems. Other possible side effects are: Headache, dizziness, nausea, vomiting. This is not an exhaustive list, and you should consult your doctor or pharmacist for more information and to report any unexpected side effects.

• If you miss a dose of Clopistatus ASP 75/150mg Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep CLOPISTATUS ASP 75/150MG TAB 1X15 away from the reach of children and pets.
• Store CLOPISTATUS ASP 75/150MG TAB 1X15 at room temperature.

• Take CLOPISTATUS ASP 75/150MG TABLET 15'S exactly as prescribed by your doctor. Do not change the dosage or stop taking it without consulting your healthcare provider, as this can increase your risk of serious cardiovascular events like heart attack or stroke. This medicine is often prescribed after a heart attack or stroke to prevent future events.
• Be aware of potential bleeding risks while taking CLOPISTATUS ASP 75/150MG TABLET 15'S. This medication thins your blood, so you may bleed more easily from cuts or injuries. Inform your doctor if you experience any unusual or prolonged bleeding, such as nosebleeds, bleeding gums, blood in your urine or stool, or excessive bruising. Avoid activities that might cause injury.
• Inform your doctor and dentist that you are taking CLOPISTATUS ASP 75/150MG TABLET 15'S before any surgery, dental procedure, or invasive medical test. They may advise you to stop taking the medication temporarily to reduce the risk of excessive bleeding during the procedure. Follow their instructions carefully.
• CLOPISTATUS ASP 75/150MG TABLET 15'S can interact with other medications, including over-the-counter drugs, herbal supplements, and vitamins. Make sure to tell your doctor about all the medications you are currently taking to avoid potential drug interactions. Specifically, be cautious when taking other blood thinners (like warfarin or heparin), NSAIDs (like ibuprofen or naproxen), or certain antidepressants.
• If you miss a dose of CLOPISTATUS ASP 75/150MG TABLET 15'S, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up. Consistency in taking this medication is crucial for its effectiveness in preventing blood clots.

• CLOPISTATUS ASP 75/150MG TABLET 15'S can be taken with or without food. Food does not significantly affect the absorption or effectiveness of this medication. However, it is advisable to take it at the same time each day to maintain consistent blood levels.