CLONIL 25MG TABLET 15'S
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CLONIL 25MG TABLET 15'SCLONIL 25MG TABLET 15'SCLONIL 25MG TABLET 15'S
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CLONIL 25MG TABLET 15'S

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CLONIL 25MG TABLET 15'S

By INTAS PHARMACEUTICALS LIMITED

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99.69

₹84.74

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Product DetailsArrow

Content Reviewed By:

Dr. Sanjay Mehta

, (MBBS)

Written By:

Ms. Kavita Desai

, (B.Pharm)

About CLONIL 25MG TABLET 15'S

  • Clonil 25 is a branded formulation of clomipramine hydrochloride, a tricyclic antidepressant (TCA). It is most commonly prescribed for obsessive–compulsive disorder (OCD), and may also be used in certain anxiety disorders, depressive disorders, and other conditions as judged appropriate by a specialist. The medicine acts primarily by inhibiting the reuptake of serotonin and, to a lesser extent, norepinephrine in the brain, thereby increasing the availability of these neurotransmitters at synaptic sites. This modulation of neurotransmitters helps reduce intrusive thoughts, compulsive behaviors, and depressive symptoms over time. Clonil 25 is usually taken by mouth and is intended for use under close medical supervision, especially at the start of therapy and during dose adjustments. The exact dose, frequency, and duration of treatment must be determined individually by a qualified physician based on the patient’s age, diagnosis, severity of symptoms, response to treatment, and coexisting medical conditions. Patients should not start, stop, or change the dose on their own, as abrupt changes can lead to withdrawal symptoms, symptom rebound, or other complications. Commonly reported side effects include dry mouth, constipation, blurred vision, dizziness, drowsiness, increased sweating, weight changes, and tremor. Some people may experience palpitations, changes in blood pressure, or sexual dysfunction. Many side effects are dose related and may lessen as the body adjusts to the medicine, but persistent or troublesome symptoms should be discussed with the prescribing doctor. Serious but less common adverse effects can include cardiac rhythm disturbances, seizures, severe allergic reactions, and significant mood or behavior changes, including emergence or worsening of suicidal thoughts, particularly in younger patients. Clonil 25 may not be suitable for everyone. It is generally used with caution or avoided in people with certain heart diseases (such as recent heart attack, significant arrhythmias, or conduction abnormalities), uncontrolled epilepsy, severe liver impairment, untreated narrow‑angle glaucoma, or urinary retention due to prostate enlargement. It can interact with many other medicines, including monoamine oxidase inhibitors (MAOIs), certain antidepressants, antipsychotics, antiarrhythmics, and drugs that affect heart rhythm or serotonin levels. Because of the risk of serotonin syndrome, it should not be combined with other serotonergic agents without careful monitoring. The onset of therapeutic benefit in OCD and depression is usually gradual. Patients may need several weeks of continuous treatment before noticing clear improvement. It is important to continue taking Clonil 25 as prescribed even if symptoms do not improve immediately, unless a doctor advises otherwise. Regular follow‑up visits allow the clinician to monitor efficacy, side effects, blood pressure, heart rate, and, when indicated, electrocardiogram (ECG) or laboratory parameters. Clonil 25 can cause drowsiness, impaired concentration, and blurred vision, which may affect the ability to drive or operate machinery. Alcohol and other central nervous system depressants can enhance these effects and are generally discouraged. In older adults, the medicine is used cautiously because of increased sensitivity to side effects such as confusion, falls, and cardiac events. In children and adolescents, use is typically restricted to specialist care with close monitoring for behavioral changes. Patients should inform their doctor about all current medications, over‑the‑counter products, herbal supplements, and pre‑existing conditions before starting Clonil 25. Any sudden mood changes, suicidal thoughts, chest pain, severe dizziness, fainting, seizures, or signs of allergic reaction (such as rash, swelling of the face or tongue, or difficulty breathing) require urgent medical attention. Long‑term treatment should be reviewed periodically to confirm ongoing need, and any decision to discontinue should involve a gradual taper under medical supervision to minimize withdrawal symptoms and relapse risk.

Uses of CLONIL 25MG TABLET 15'S

  • Feelings of persistent sadness and loss of interest, impacting daily life.
  • Characterized by persistent, intrusive thoughts and repetitive behaviors performed to reduce anxiety.
  • Managing Narcolepsy, a chronic sleep disorder causing overwhelming daytime drowsiness and sudden sleep attacks.

How CLONIL 25MG TABLET 15'S Works

  • CLONIL 25MG TABLET 15'S is classified as a tricyclic antidepressant, a medication primarily used to treat depression and obsessive-compulsive disorder (OCD). It functions by influencing the balance of certain naturally occurring chemicals within the brain, specifically neurotransmitters.
  • These neurotransmitters, such as serotonin and norepinephrine, play a crucial role in regulating mood, behavior, and overall mental well-being. In individuals with depression or OCD, the levels of these neurotransmitters may be imbalanced, leading to symptoms like persistent sadness, loss of interest, intrusive thoughts, and repetitive behaviors.
  • CLONIL 25MG TABLET 15'S works by inhibiting the reuptake of serotonin and norepinephrine in the brain. Reuptake is the process where neurotransmitters are reabsorbed by the nerve cells after they have transmitted a signal. By blocking this reuptake, CLONIL 25MG TABLET 15'S effectively increases the concentration of these neurotransmitters in the synaptic cleft, the space between nerve cells.
  • This increased availability of serotonin and norepinephrine helps to improve mood, reduce anxiety, and alleviate the symptoms of depression and OCD. It's important to note that the effects of CLONIL 25MG TABLET 15'S, like other antidepressants, may not be immediately noticeable, and it can take several weeks of consistent use to experience the full therapeutic benefits. Regular monitoring by a healthcare professional is essential to ensure the medication is working effectively and to manage any potential side effects.

Side Effects of CLONIL 25MG TABLET 15'SArrow

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them. CLONIL 25MG TABLET 15'S can cause several side effects.

  • Constipation
  • Nausea
  • Altered libido
  • Dizziness
  • Fatigue
  • Increased appetite
  • Sweating
  • Drowsiness
  • Urinary incontinence
  • Tremors
  • Weight gain
  • Aggravation of depression
  • Agitation
  • Anxiety
  • Blurred vision
  • Delirium (acute confusional state)
  • ECG changes
  • Headache
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Ringing in ear
  • Sleep disorder
  • Confusion
  • Hallucination
  • Mania
  • Micturition disorders
  • Altered blood sugar level

Safety Advice for CLONIL 25MG TABLET 15'SArrow

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Heart and Blood Pressure

Use with caution

Clonil 25 can affect heart rhythm and blood pressure due to its tricyclic antidepressant properties.

How to store CLONIL 25MG TABLET 15'S?Arrow

  • Keep CLONIL 25MG TAB 1X15 away from the reach of children and pets.
  • Store CLONIL 25MG TAB 1X15 at room temperature.

Benefits of CLONIL 25MG TABLET 15'SArrow

  • **Depression:** CLONIL 25MG TABLET 15'S is believed to work by influencing the balance of specific brain chemicals, notably serotonin. This can lead to improvements in mood, increased feelings of well-being, reduced anxiety and tension, better sleep quality, and enhanced energy levels. It's often prescribed for depression that hasn't responded to other treatments. Consistent, regular use as prescribed is key for optimal effectiveness, and abrupt cessation should be avoided. Because CLONIL 25MG TABLET 15'S helps balance chemicals in the brain it improves overall mental health.
  • **Obsessive-Compulsive Disorder (OCD):** OCD is a mental health condition characterized by a cycle of obsessions (unwanted, repetitive thoughts, images, or urges) and compulsions. CLONIL 25MG TABLET 15'S can alleviate OCD symptoms by increasing serotonin levels in the brain. Compared to other medications, it generally has fewer side effects and is typically taken once daily. It is important to continue taking it until your doctor advises you to stop. This helps to manage the distressing feelings associated with OCD.
  • **Treatment of Narcolepsy (Uncontrollable Daytime Sleepiness):** Narcolepsy is a sleep disorder marked by excessive daytime drowsiness, potentially accompanied by sleep paralysis, hallucinations, and cataplexy (sudden loss of muscle control). CLONIL 25MG TABLET 15'S stimulates the brain, promoting wakefulness. Furthermore, it addresses the associated symptoms and regulates the sleep-wake cycle. This can restore normal sleep patterns and improve overall quality of life, leading to increased energy and enhanced performance in daily activities. With improved sleep quality, focus and concentration gets better.

How to use CLONIL 25MG TABLET 15'SArrow

  • Always take CLONIL 25MG TABLET 15'S exactly as your doctor has instructed. It is crucial to follow their dosage and timing recommendations for the best results.
  • This medication is intended to be swallowed whole with a glass of water. Avoid chewing, crushing, or breaking the tablet, as this could affect how the medicine is absorbed and works in your body. Doing so can also lead to unwanted side effects.
  • For optimal absorption and to minimize potential stomach upset, it is best to take CLONIL 25MG TABLET 15'S with food. This helps to ensure a consistent level of the medication in your bloodstream.
  • If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for a missed one.
  • It's important to continue taking CLONIL 25MG TABLET 15'S for the full duration prescribed by your doctor, even if you start to feel better. Stopping the medication prematurely could cause your symptoms to return or worsen.
  • If you have any questions or concerns about how to take CLONIL 25MG TABLET 15'S, or if you experience any unusual side effects, consult with your doctor or pharmacist for further guidance.

Quick Tips for CLONIL 25MG TABLET 15'SArrow

  • CLONIL 25MG TABLET 15'S may require 4 to 6 weeks to demonstrate noticeable effects. It is crucial to adhere to the prescribed dosage and continue the medication as directed by your healthcare provider, even if you don't experience immediate relief. Consistency is key to achieving the desired therapeutic outcome.
  • This medication can induce drowsiness. For optimal safety, take CLONIL 25MG TABLET 15'S at bedtime. Refrain from operating machinery or engaging in activities that demand heightened alertness until you are fully aware of how the medicine affects you. Prioritize caution and avoid situations where impaired concentration could pose a risk.
  • It is strongly advised to avoid alcohol consumption while taking CLONIL 25MG TABLET 15'S, as the combination can significantly amplify drowsiness and potentially lead to adverse effects. Alcohol can interact with the medication, intensifying its sedative properties and increasing the risk of impaired coordination and judgment.
  • Regularly monitor your weight throughout the treatment period, as CLONIL 25MG TABLET 15'S may contribute to weight gain and an increased appetite. Implementing a balanced diet and engaging in regular physical activity can help manage these potential side effects. Consult your doctor or a registered dietitian for personalized guidance on maintaining a healthy weight.
  • Promptly communicate with your doctor if you experience sudden mood changes or develop suicidal thoughts. These symptoms require immediate medical attention. Do not hesitate to seek professional help if you find yourself struggling with your mental health.
  • To maximize the effectiveness of CLONIL 25MG TABLET 15'S, maintain open communication with your healthcare provider regarding any other medications or supplements you are taking. This helps to avoid potential drug interactions that could compromise the medication's efficacy or lead to undesirable side effects. Your doctor needs a complete picture of your health profile to provide the best possible care.

FAQs

<h3 class=bodySemiBold>Can CLONIL 25MG TABLET 15'S cause impotence?</h3>Arrow

Yes, CLONIL 25MG TABLET 15'S can cause impotence. Both men and women may experience decreased sexual desire and inability to have an organsm. In males, difficulty in maintaining erection (impotence) or painful ejaculation may be observed. You should consult your doctor immediately if you face any such problems while taking CLONIL 25MG TABLET 15'S.

<h3 class=bodySemiBold>Is CLONIL 25MG TABLET 15'S safe?</h3>Arrow

Yes, CLONIL 25MG TABLET 15'S is safe to use if taken in the dose and duration prescribed by the doctor. CLONIL 25MG TABLET 15'S is a medicine that treats Obsessive-Compulsive Disorder (OCD), stabilises mood and behavior. It restores the chemical imbalance in the brain and creates a feeling of well being.

<h3 class=bodySemiBold>What are the side effects of CLONIL 25MG TABLET 15'S?</h3>Arrow

CLONIL 25MG TABLET 15'S may cause side effects like difficulty or inability to pass urine, altered libido, constipation, dryness in mouth, ejaculation disorder, indigestion and sleepiness. Please consult your doctor if these side effects worry you. The doctor may suggest ways to treat or prevent them.

<h3 class=bodySemiBold>What happens if I take an overdose of CLONIL 25MG TABLET 15'S?</h3>Arrow

If you have taken an overdose of CLONIL 25MG TABLET 15'S, you may experience symptoms such as drowsiness, restlessness, agitation and delirium (disturbed state of mind with restlessness and mental confusion). You may also experience severe sweating, fast heartbeat, feeling of faint, seizures (fits), and you may even go into a state of coma. Immediately consult your doctor and seek medical help if you think you have taken too much of this medicine.

<h3 class=bodySemiBold>If I am feeling better, can I stop taking CLONIL 25MG TABLET 15'S?</h3>Arrow

No, do not stop taking CLONIL 25MG TABLET 15'S suddenly even if you are feeling better as it may worsen your condition and also cause withdrawal symptoms such as dizziness, nausea, vomiting, headache, weakness, sleep problems, fever, and irritability. Continue taking CLONIL 25MG TABLET 15'S for the duration as prescribed by your doctor to get maximum benefit. If any of the side effects are bothering you, consult your doctor. In case you have completed your course of treatment, your doctor will reduce your dose gradually before taking you off this medicine completely.

What is Clonil 25 and what is it used for?Arrow

Clonil 25 is a brand of clomipramine, a tricyclic antidepressant. It is primarily used to treat obsessive–compulsive disorder (OCD), where it helps reduce intrusive thoughts and repetitive behaviors. It may also be prescribed for certain depressive disorders, panic disorder, and other anxiety‑related conditions, depending on a specialist’s judgment. The decision to use Clonil 25 is based on an assessment of symptoms, medical history, and response to previous treatments.

How does Clonil 25 work in the body?Arrow

Clonil 25 contains clomipramine, which works mainly by inhibiting the reuptake of serotonin and, to a lesser extent, norepinephrine in the brain. By blocking their reuptake into nerve cells, it increases the levels of these neurotransmitters in the synaptic cleft, enhancing neurotransmission in pathways involved in mood and anxiety regulation. This mechanism is thought to underlie its benefits in OCD and depression, although the full therapeutic effect typically appears only after several weeks of continuous use.

How long does it take for Clonil 25 to start working?Arrow

The onset of benefit with Clonil 25 is gradual. Some people may notice mild improvement in sleep or anxiety within 1 to 2 weeks, but significant reduction in obsessive thoughts, compulsions, or depressive symptoms often requires 3 to 6 weeks or longer of regular treatment. The exact timeframe varies between individuals. It is important not to stop the medicine prematurely because of delayed response; any concerns about lack of improvement should be discussed with the prescribing doctor.

Can I stop taking Clonil 25 suddenly if I feel better?Arrow

Clonil 25 should not be stopped abruptly unless a doctor specifically instructs you to do so for safety reasons. Sudden discontinuation can lead to withdrawal‑like symptoms such as nausea, headache, dizziness, irritability, sleep disturbance, and a rapid return or worsening of the underlying condition. When treatment needs to be stopped, the dose is usually reduced gradually over days to weeks under medical supervision to minimize these risks.

What are the common side effects of Clonil 25?Arrow

Common side effects of Clonil 25 include dry mouth, constipation, blurred vision, drowsiness, dizziness, increased sweating, tremor, and changes in appetite or weight. Some people may experience palpitations, mild changes in blood pressure, or sexual dysfunction such as decreased libido or difficulty with orgasm. Many of these effects are related to the anticholinergic and sedative properties of clomipramine and may lessen as the body adapts. Persistent, severe, or distressing side effects should be reported to a healthcare professional.

Are there serious risks associated with Clonil 25?Arrow

Yes, although serious adverse effects are less common, they can occur and require prompt medical attention. These include significant changes in heart rhythm, chest pain, severe dizziness or fainting, seizures, marked confusion, severe constipation with abdominal pain, difficulty urinating, and signs of allergic reaction such as rash, swelling of the face or tongue, or breathing difficulty. Mood or behavior changes, including new or worsening suicidal thoughts, agitation, or unusual aggression, particularly in younger patients, also warrant urgent evaluation.

Can Clonil 25 be taken with other antidepressants or psychiatric medicines?Arrow

Clonil 25 can interact with several other psychiatric medicines, and combinations must be carefully managed by a specialist. It should not be used with monoamine oxidase inhibitors (MAOIs) or within a specified washout period because of the risk of serious reactions. Combining clomipramine with other serotonergic drugs, such as certain SSRIs, SNRIs, or triptans, can increase the risk of serotonin syndrome, a potentially life‑threatening condition. It may also interact with antipsychotics, mood stabilizers, and medicines that affect heart rhythm. Always inform your doctor about all medicines you are taking before starting Clonil 25.

Is Clonil 25 habit forming or addictive?Arrow

Clonil 25 is not considered addictive in the way that substances of abuse are, and it does not typically produce craving or drug‑seeking behavior. However, the body can become accustomed to its presence, and abrupt discontinuation may lead to withdrawal‑like symptoms and symptom rebound. For this reason, it should be taken exactly as prescribed and tapered gradually when it is time to stop, under medical guidance.

Can I drink alcohol while taking Clonil 25?Arrow

Alcohol is generally discouraged while taking Clonil 25. Both alcohol and clomipramine depress the central nervous system and can increase drowsiness, dizziness, impaired coordination, and judgment. This combination may raise the risk of accidents, falls, and other adverse events. In some individuals, alcohol can also worsen mood or anxiety symptoms and interfere with the therapeutic effect of the medicine. If you consume alcohol, discuss this with your doctor for individualized advice.

What should I do if I miss a dose of Clonil 25?Arrow

If you miss a dose of Clonil 25, take it as soon as you remember, unless it is almost time for your next scheduled dose. If it is close to the next dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to make up for a missed one, as this may increase the risk of side effects such as excessive drowsiness, heart rhythm changes, or other adverse reactions. If you frequently forget doses, speak with your healthcare provider about strategies to improve adherence.

Is Clonil 25 safe for older adults?Arrow

Clonil 25 can be used in older adults, but it requires particular caution. Older patients are more sensitive to side effects such as confusion, dizziness, low blood pressure on standing, urinary retention, constipation, and heart rhythm disturbances. They also have a higher risk of falls and fractures. Doses are often started lower and adjusted more slowly, with close monitoring of blood pressure, heart function, and overall tolerability. Any sudden change in mental status, balance, or urinary habits should be reported promptly.

References

Book Icon

Clomipramine hydrochloride. Whitby, Ontario, Canada: Patheon Inc.; [revised Jun. 2014]. (online) Available from:

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Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. (online) Available from:

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Central Drugs Standard Control Organisation (CDSCO). (online) Available from:

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Clomipramine Hydrochlorid [Drug Label]. Hazelwood, MO: Mallinckrodt Inc.; 2007. (online) Available from:

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