CLOPISTATUS ASP 75/75MG TABLET 15'S

How CLOPISTATUS ASP 75/75MG TABLET 15'S Works

• CLOPISTATUS ASP 75/75MG TABLET 15'S is a combination medication containing clopidogrel and aspirin, both of which are antiplatelet agents. This means they help prevent blood clots from forming. To understand how CLOPISTATUS ASP works, it's important to understand the role of platelets in the body.
• Platelets are small, disc-shaped cells in your blood that play a crucial role in blood clotting. When a blood vessel is injured, platelets rush to the site of injury and clump together to form a plug. This plug helps to stop the bleeding. However, in certain conditions, such as atherosclerosis (hardening of the arteries), platelets can become overactive and form clots inside blood vessels, leading to serious problems like heart attack or stroke.
• Clopidogrel works by inhibiting the binding of ADP (adenosine diphosphate) to its platelet receptor. ADP is a chemical that stimulates platelet aggregation. By blocking ADP, clopidogrel prevents platelets from sticking together. Specifically, clopidogrel is a prodrug, meaning it needs to be converted into its active form by enzymes in the liver. Once activated, it irreversibly modifies the platelet ADP receptor, called P2Y12. This irreversible modification means that the platelet is affected for its entire lifespan (about 7-10 days). Therefore, even after stopping clopidogrel, it takes several days for platelet function to return to normal.
• Aspirin, on the other hand, works by inhibiting the production of thromboxane A2, a substance that also promotes platelet aggregation. Aspirin achieves this by irreversibly inhibiting an enzyme called cyclooxygenase (COX-1) in platelets. This inhibition reduces the production of thromboxane A2, thereby reducing platelet activation and aggregation. Like clopidogrel, the effect of aspirin on platelets is irreversible for the life of the platelet.
• The combination of clopidogrel and aspirin in CLOPISTATUS ASP provides a dual antiplatelet effect. By inhibiting platelet aggregation through two different mechanisms, this combination is more effective than either drug alone in preventing blood clots. This is particularly important in individuals at high risk of heart attack or stroke, such as those with a history of these events, those with unstable angina, or those who have undergone percutaneous coronary intervention (PCI) like stent placement. The combined effect helps to keep blood flowing smoothly through arteries, reducing the risk of dangerous clots that can block blood flow to the heart or brain.
• In summary, CLOPISTATUS ASP 75/75MG TABLET 15'S works by using two different medications (clopidogrel and aspirin) to make platelets less sticky, thereby preventing harmful blood clots from forming and reducing the risk of heart attack and stroke. It's crucial to take this medication exactly as prescribed by your doctor to achieve the optimal benefit and minimize the risk of side effects.

Common side effects of CLOPISTATUS ASP 75/75MG TABLET may include: * Increased risk of bleeding (e.g., nosebleeds, easy bruising) * Stomach pain * Diarrhea * Indigestion * Heartburn * Nausea Uncommon side effects may include: * Headache * Dizziness * Constipation * Vomiting * Skin rash or itching * Allergic reactions * Tingling or numbness * Serious bleeding (e.g., bleeding in the brain, stomach ulcers) * Thrombotic Thrombocytopenic Purpura (TTP) - a rare but serious blood disorder * Liver problems (indicated by jaundice or dark urine) * Kidney problems **It is important to consult your doctor immediately if you experience any severe or persistent side effects.**

• If you miss a dose of Clopistatus ASP 75/75mg Tablet 15's, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the one you missed.

• Keep CLOPISTATUS ASP 75/75MG TAB 1X15 away from the reach of children and pets.
• Store CLOPISTATUS ASP 75/75MG TAB 1X15 at room temperature.

• **Take Clopistatus ASP as directed by your doctor:** Always follow your doctor's instructions regarding dosage and timing. Do not self-adjust the dose or discontinue the medication without consulting your healthcare provider. This medication is typically prescribed to prevent blood clots after certain heart conditions or procedures.
• **Be aware of bleeding risks:** Clopistatus ASP contains antiplatelet agents, which can increase the risk of bleeding. Inform your doctor about all medications you are taking, including over-the-counter drugs and herbal supplements, as they may interact with Clopistatus ASP and further increase bleeding risks. Report any unusual bleeding or bruising to your doctor immediately.
• **Monitor for gastrointestinal side effects:** Some individuals may experience gastrointestinal side effects such as stomach upset, nausea, or abdominal pain while taking Clopistatus ASP. Taking the medication with food may help reduce these symptoms. If side effects persist or worsen, consult your doctor.
• **Inform healthcare providers before procedures:** Before undergoing any surgical, dental, or medical procedures, inform your healthcare providers that you are taking Clopistatus ASP. They may advise you to temporarily discontinue the medication to minimize bleeding risks during the procedure. Always follow their instructions carefully.
• **Maintain a healthy lifestyle:** While taking Clopistatus ASP, maintaining a healthy lifestyle can further support your cardiovascular health. This includes following a balanced diet low in saturated and trans fats, engaging in regular physical activity, avoiding smoking, and managing stress effectively. Consult your doctor for personalized recommendations.

• It is best to take CLOPISTATUS ASP 75/75MG TABLET 15'S after food to avoid stomach upset. However, consult your doctor for personalized advice.