CLOPIVAS AP 75MG TABLET 15'S

How CLOPIVAS AP 75MG TABLET 15'S Works

• CLOPIVAS AP 75MG TABLET 15'S is a combination medication containing two active ingredients: clopidogrel and aspirin. Both components work synergistically to prevent blood clot formation, primarily in individuals at risk of cardiovascular events such as heart attack or stroke.
• Clopidogrel belongs to a class of drugs called antiplatelet agents. Platelets are small blood cells that play a crucial role in blood clotting. When blood vessels are injured, platelets aggregate at the site of injury and initiate the clotting process. Clopidogrel works by inhibiting the binding of adenosine diphosphate (ADP) to its receptor on platelets. ADP is a chemical signal that promotes platelet activation and aggregation. By blocking ADP binding, clopidogrel effectively reduces platelet activation and prevents them from clumping together to form a clot.
• Aspirin, also an antiplatelet agent, has a different mechanism of action. It inhibits the production of thromboxane A2, a substance that promotes platelet aggregation and vasoconstriction (narrowing of blood vessels). Aspirin irreversibly acetylates cyclooxygenase (COX) enzymes, which are responsible for the synthesis of thromboxane A2. By inhibiting COX enzymes, aspirin reduces thromboxane A2 levels, thereby decreasing platelet aggregation and promoting blood vessel dilation.
• The combined action of clopidogrel and aspirin provides a dual antiplatelet effect. Clopidogrel inhibits ADP-mediated platelet activation, while aspirin inhibits thromboxane A2-mediated platelet activation. This dual inhibition significantly reduces the risk of blood clot formation compared to either drug alone. This is particularly beneficial in patients with conditions like acute coronary syndrome (ACS), recent stroke, or peripheral artery disease, where the risk of thrombotic events is elevated.
• CLOPIVAS AP 75MG TABLET 15'S is typically prescribed for long-term use to maintain its antiplatelet effect. It's crucial to take the medication as directed by your healthcare provider and to adhere to the prescribed dosage schedule. Discontinuing the medication without consulting your doctor can increase the risk of blood clot formation and subsequent cardiovascular events. Always inform your doctor about any other medications you are taking, including over-the-counter drugs and herbal supplements, as they may interact with CLOPIVAS AP 75MG TABLET 15'S. It is also important to monitor for any signs of bleeding, such as easy bruising, nosebleeds, or blood in the urine or stool, and to report them to your doctor promptly.

Common side effects of CLOPIVAS AP 75MG TABLET may include: Increased risk of bleeding (e.g., nosebleeds, easy bruising), upset stomach, diarrhea, abdominal pain, indigestion, heartburn. Less common but potentially serious side effects include: Severe allergic reactions (rash, itching/swelling, especially of the face/tongue/throat, severe dizziness, trouble breathing), signs of bleeding problems (e.g., unusual bleeding, blood in the urine/stool, black/tarry stools, coughing up blood), signs of a blood clot (e.g., chest pain, shortness of breath, sudden numbness/weakness on one side of the body), liver problems (e.g., persistent nausea/vomiting, severe abdominal pain, yellowing of the eyes/skin), and Thrombotic Thrombocytopenic Purpura (TTP) - a rare but serious blood disorder.

• If you miss a dose of CLOPIVAS AP 75MG TABLET 15'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the one you missed.

• Keep CLOPIVAS AP 75MG TAB 1X15 away from the reach of children and pets.
• Store CLOPIVAS AP 75MG TAB 1X15 at room temperature.

• **Take CLOPIVAS AP 75MG TABLET as prescribed:** Always follow your doctor's instructions regarding dosage and timing. Do not alter the dosage or stop taking the medication without consulting your healthcare provider, as this can increase your risk of heart attack or stroke. This medication usually taken orally, with or without food.
• **Be aware of bleeding risks:** CLOPIVAS AP 75MG TABLET can increase your risk of bleeding. Avoid activities that may cause injury, such as contact sports or using sharp objects. Inform your doctor and dentist about taking this medication before any surgery or dental procedure. Watch out for signs of bleeding like prolonged bleeding from cuts, nosebleeds, unusual bruising, or blood in your urine or stool.
• **Inform your doctor about other medications:** Before starting CLOPIVAS AP 75MG TABLET, tell your doctor about all the medications, supplements, and herbal products you are taking. Certain medications, such as NSAIDs (e.g., ibuprofen, naproxen), blood thinners (e.g., warfarin), and some antidepressants, can interact with clopidogrel and increase the risk of bleeding. Aspirin is a component of this medicine hence caution is advised.
• **Monitor for side effects:** While CLOPIVAS AP 75MG TABLET is generally safe, it can cause side effects. Common side effects include headache, dizziness, nausea, and diarrhea. Contact your doctor if you experience any severe or persistent side effects, such as severe stomach pain, allergic reactions (rash, itching, swelling), or signs of a blood disorder (e.g., fever, chills, weakness).
• **Maintain a healthy lifestyle:** CLOPIVAS AP 75MG TABLET is more effective when combined with a healthy lifestyle. Follow a balanced diet low in saturated and trans fats, cholesterol, and sodium. Engage in regular physical activity, quit smoking, and manage stress. These lifestyle changes can further reduce your risk of cardiovascular events. Regular monitoring of blood pressure and cholesterol levels is also recommended.

• CLOPIVAS AP 75MG TABLET 15'S can be taken with or without food. Food does not significantly affect the absorption or effectiveness of this medication. However, it is advisable to take it at the same time each day to maintain consistent drug levels in your body.