CRINAC SP TABLET 10'S

How CRINAC SP TABLET 10'S Works

• CRINAC SP TABLET 10'S is a combination medication designed to alleviate pain and inflammation. It leverages the synergistic effects of its three active ingredients: Aceclofenac, Paracetamol, and Serratiopeptidase, each targeting different aspects of the pain and inflammation cascade.
• Aceclofenac, a non-steroidal anti-inflammatory drug (NSAID), inhibits the production of prostaglandins, which are hormone-like substances that contribute to pain, inflammation, and fever. It achieves this by blocking the cyclooxygenase (COX) enzymes, specifically COX-1 and COX-2. By reducing prostaglandin synthesis, Aceclofenac effectively diminishes pain and swelling.
• Paracetamol, also known as Acetaminophen, is an analgesic and antipyretic (fever reducer). While its exact mechanism of action is not fully understood, it's believed that Paracetamol primarily works by inhibiting prostaglandin synthesis in the central nervous system (brain and spinal cord). This action reduces pain signals and lowers body temperature. Paracetamol's effect is more pronounced in reducing fever and pain than in reducing inflammation.
• Serratiopeptidase is a proteolytic enzyme, meaning it breaks down proteins. It helps in reducing inflammation by breaking down bradykinin, a peptide that induces pain and inflammation. Serratiopeptidase also enhances the action of antibiotics by facilitating their penetration into the site of infection through degradation of extracellular matrix and breakdown of biofilm. Furthermore, Serratiopeptidase has fibrinolytic, anti-edemic (prevents swelling) and anti-inflammatory activity.
• In combination, Aceclofenac addresses pain and inflammation at the site of injury, Paracetamol manages pain and fever centrally, and Serratiopeptidase further reduces inflammation and promotes healing. This multi-pronged approach makes CRINAC SP TABLET 10'S effective in managing various painful conditions, including musculoskeletal pain, post-operative pain, and pain associated with inflammation.

Common side effects of Crinac SP Tablet may include nausea, vomiting, stomach pain, heartburn, diarrhea, loss of appetite, and skin rash. Less common but potentially serious side effects include allergic reactions (such as swelling of the face, lips, tongue, or throat; difficulty breathing; hives), gastrointestinal bleeding (indicated by black, tarry stools or vomiting blood), liver problems (indicated by jaundice, dark urine, fatigue), kidney problems (indicated by changes in urine output, swelling), increased risk of bleeding or bruising, and severe skin reactions (such as Stevens-Johnson syndrome or toxic epidermal necrolysis). Other possible side effects are headache, dizziness, drowsiness, insomnia, anxiety, blurred vision, increased sweating, and changes in blood pressure.

• If you miss a dose of Crinac SP Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

• Keep CRINAC SP TAB 1X10 away from the reach of children and pets.
• Store CRINAC SP TAB 1X10 at room temperature.

• Take CRINAC SP TABLET 10'S as prescribed by your doctor. Adhere strictly to the prescribed dosage and duration to maximize its benefits in reducing pain and inflammation.
• It is best to take CRINAC SP TABLET 10'S after meals to minimize potential stomach upset. If you experience persistent gastrointestinal issues, consult your doctor for advice on managing side effects or alternative medications.
• Inform your doctor about any pre-existing medical conditions, especially liver or kidney disease, heart problems, or bleeding disorders, before starting CRINAC SP TABLET 10'S. This ensures the medication is safe and appropriate for you.
• Avoid combining CRINAC SP TABLET 10'S with other pain relievers, particularly NSAIDs, unless specifically directed by your doctor. Combining medications can increase the risk of adverse effects and complications.
• If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using CRINAC SP TABLET 10'S. The medication's safety during pregnancy and breastfeeding has not been fully established, and medical advice is essential.
• Be aware of potential side effects such as nausea, vomiting, diarrhea, or allergic reactions. If you experience severe or persistent side effects, seek immediate medical attention.
• Store CRINAC SP TABLET 10'S in a cool, dry place, away from direct sunlight and moisture. Keep it out of reach of children to prevent accidental ingestion.

• It is recommended to take CRINAC SP TABLET 10'S with or without food to avoid stomach upset.
• However, if you experience persistent stomach irritation, taking it with food may help.
• Avoid consuming large amounts of fatty foods immediately before or after taking this medicine, as it may affect absorption.