DAPEFY 10MG TABLET 14'S
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DAPEFY 10MG TABLET 14'S
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DAPEFY 10MG TABLET 14'S

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DAPEFY 10MG TABLET 14'S

By SUN PHARMACEUTICAL INDUSTRIES LTD

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223.13

₹189.66

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10

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Product DetailsArrow

Content Reviewed By:

Dr. Sanjay Mehta

, (MBBS)

Written By:

Ms. Kavita Desai

, (B.Pharm)

About DAPEFY 10MG TABLET 14'S

  • Dapefy 10 is a prescription medicine that contains dapagliflozin 10 mg, a sodium-glucose co-transporter 2 (SGLT2) inhibitor used in the management of type 2 diabetes mellitus and, in some patients, heart failure or chronic kidney disease, as directed by a doctor. It works primarily in the kidneys by blocking the SGLT2 protein in the proximal renal tubules, which reduces glucose reabsorption and increases the amount of glucose excreted in the urine. This helps lower blood sugar levels independently of insulin and can also lead to modest weight loss and a reduction in blood pressure in many patients. Dapefy 10 is usually prescribed as part of a comprehensive treatment plan that includes diet control, regular physical activity, and routine blood sugar monitoring. It may be used alone or in combination with other antidiabetic medicines such as metformin, DPP-4 inhibitors, GLP-1 receptor agonists, or insulin, depending on individual clinical needs. The choice of combination and timing of administration should always be determined by a qualified healthcare professional after assessing kidney function, cardiovascular risk, and other comorbidities. Common side effects associated with dapagliflozin-containing products include increased urination, genital fungal infections (such as yeast infections in both men and women), urinary tract infections, thirst, and mild dehydration. Because the medicine increases glucose in the urine, it can create a favorable environment for fungal and some bacterial growth in the genital and urinary tract areas. Good personal hygiene, adequate fluid intake (unless otherwise restricted), and early reporting of symptoms like burning during urination, unusual discharge, or genital itching are important. In some patients, SGLT2 inhibitors have been associated with rare but serious adverse effects such as diabetic ketoacidosis (DKA), even when blood sugar levels are not extremely high. Symptoms may include nausea, vomiting, abdominal pain, difficulty breathing, confusion, and unusual fatigue. Patients should be educated about these warning signs and instructed to seek urgent medical attention if they occur. The medicine may need to be temporarily stopped before major surgery, during severe illness, or in situations of reduced oral intake, as advised by the treating physician. Kidney function must be assessed before starting Dapefy 10 and monitored regularly, because the effectiveness and safety of dapagliflozin depend on adequate renal function. In patients with significantly reduced kidney function, the glucose-lowering effect may be diminished, and the risk–benefit balance may change. The medicine is not intended for the treatment of type 1 diabetes or diabetic ketoacidosis. It should not be used in children unless specifically recommended by a specialist, as safety and efficacy data may be limited in certain age groups. Always follow your doctor’s instructions and do not adjust or discontinue the medicine on your own.

Uses of DAPEFY 10MG TABLET 14'S

  • Type 2 diabetes mellitus: This medication helps manage blood sugar levels in individuals with type 2 diabetes mellitus, contributing to better health outcomes.
  • Heart Failure: DAPEFY 10MG TABLET 14'S is used to treat heart failure, helping to improve heart function and alleviate symptoms.

How DAPEFY 10MG TABLET 14'S Works

  • DAPEFY 10MG TABLET 14'S works by inhibiting a protein in the kidneys called sodium-glucose cotransporter 2 (SGLT2).
  • SGLT2 is responsible for reabsorbing glucose back into the bloodstream as it is filtered through the kidneys, so by inhibiting this protein, DAPEFY 10MG TABLET 14'S allows the excess glucose to be excreted in the urine instead.
  • By increasing the excretion of glucose in the urine, DAPEFY 10MG TABLET 14'S lowers the amount of glucose in the bloodstream, which can help improve glycemic control in people with type 2 diabetes. This mechanism of action is independent of insulin, and DAPEFY 10MG TABLET 14'S can be used alone or in combination with other medications for the treatment of type 2 diabetes.
  • In addition to lowering blood glucose levels, DAPEFY 10MG TABLET 14'S can also help reduce body weight and blood pressure in people with type 2 diabetes.

Side Effects of DAPEFY 10MG TABLET 14'SArrow

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. DAPEFY 10MG TABLET 14'S can cause side effects, but not everyone experiences them.

  • Diabetic ketoacidosis
  • Urinary tract infection
  • Angioedema
  • Necrotizing fasciitis of the perineum
  • Genital infection (thrush) of your penis or vagina (signs may include irritation, itching, unusual discharge, or odor)
  • Back pain
  • Dizziness
  • Rash
  • Urgency in urination
  • Excessive thirst

Safety Advice for DAPEFY 10MG TABLET 14'SArrow

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Allergies

Contraindicated in known allergy

Do not take Dapefy 10 if you have a known allergy to dapagliflozin or any of the excipients in the formulation.

Dosage of DAPEFY 10MG TABLET 14'SArrow

  • Take DAPEFY 10MG TABLET 14'S exactly as your doctor prescribes. It's crucial to adhere to their instructions regarding dosage and timing for the best possible outcome. Avoid crushing or chewing the tablet; swallow it whole with a glass of water. This medication is most effective when taken consistently, so try to take it at the same time each day to help you remember.
  • The optimal dosage and treatment duration will be determined by your physician, considering factors like your age, body weight, and the specific nature of your condition. Do not alter the dosage yourself without consulting your doctor. Self-adjusting the medication can be harmful and may not yield the desired results. If you have any concerns or questions about the dosage, always seek clarification from your healthcare provider.
  • It's important not to discontinue DAPEFY 10MG TABLET 14'S without your doctor's explicit guidance. Suddenly stopping the medication can lead to unwanted side effects or a recurrence of your symptoms. Your doctor will gradually reduce the dosage if it's necessary to stop the medication, ensuring a safe and controlled transition. Always follow their recommendations for the safe and effective use of this medicine.

How to store DAPEFY 10MG TABLET 14'S?Arrow

  • Keep DAPEFY 10MG TAB 1X14 away from the reach of children and pets.
  • Store DAPEFY 10MG TAB 1X14 at room temperature.

Benefits of DAPEFY 10MG TABLET 14'SArrow

  • DAPEFY 10MG TABLET 14'S is designed to help manage blood sugar levels by targeting glucose reabsorption in the kidneys. It works by inhibiting the sodium-glucose cotransporter 2 (SGLT2), a protein responsible for reabsorbing glucose back into the bloodstream. By blocking this protein, DAPEFY 10MG TABLET 14'S reduces the amount of glucose that is reabsorbed, allowing excess sugar to be eliminated from the body through urine. This process effectively lowers the renal threshold for glucose, meaning that glucose starts to be excreted in the urine at lower blood sugar levels.
  • This mechanism not only helps to lower blood glucose levels but also offers additional benefits, such as potential weight loss and blood pressure reduction. The elimination of excess glucose through urine results in a calorie deficit, which can contribute to weight loss. Moreover, the reduced glucose reabsorption can have a positive impact on kidney function and overall cardiovascular health. Consult your healthcare provider to determine if DAPEFY 10MG TABLET 14'S is the right choice for managing your blood sugar and improving your overall well-being.
  • In essence, DAPEFY 10MG TABLET 14'S assists in maintaining healthy blood sugar levels by facilitating the removal of surplus glucose from the body via urine, thereby playing a crucial role in managing diabetes and promoting better metabolic health.

How to use DAPEFY 10MG TABLET 14'SArrow

  • Always adhere to your doctor's instructions when taking DAPEFY 10MG TABLET 14'S. It's crucial to follow their guidance for optimal results and to minimize potential side effects. Swallow the tablet whole; avoid crushing, chewing, or breaking it, as this could affect how the medication is released and absorbed into your system.
  • Your doctor will determine the most appropriate dosage and treatment duration based on individual factors such as your age, body weight, and the specific nature of your health condition. It's essential to attend all scheduled follow-up appointments so your doctor can monitor your progress and make any necessary adjustments to your treatment plan.
  • Consistency is key when taking DAPEFY 10MG TABLET 14'S. Try to take it at the same time each day to help maintain a steady level of medication in your body. This can improve its effectiveness and reduce the likelihood of missed doses.
  • Do not discontinue taking DAPEFY 10MG TABLET 14'S without first consulting your doctor, even if you start feeling better. Abruptly stopping the medication can lead to unwanted side effects or a worsening of your condition. If your doctor decides it's safe for you to stop taking the medication, they will provide instructions on how to gradually reduce the dosage to minimize any potential withdrawal symptoms.
  • If you have any questions or concerns about taking DAPEFY 10MG TABLET 14'S, don't hesitate to reach out to your doctor or pharmacist. They can provide personalized advice and address any worries you may have.

FAQs

Can DAPEFY 10MG TABLET 14'S cause weight loss?Arrow

Yes, DAPEFY 10MG TABLET 14'S can cause weight loss in some individuals. One of the effects of DAPEFY 10MG TABLET 14'S is the excretion of excess glucose in the urine. It leads to a loss of calories and can contribute to weight reduction.

How does DAPEFY 10MG TABLET 14'S work?Arrow

DAPEFY 10MG TABLET 14'S reduces glucose reabsorption and lowers the renal threshold for glucose. It works by removing excess glucose from your body via your urine and lowering the sugar in your blood.

Is DAPEFY 10MG TABLET 14'S used for type 1 diabetes?Arrow

DAPEFY 10MG TABLET 14'S is not approved for use in type 1 diabetes. It is specifically indicated for the treatment of type 2 diabetes mellitus.

Can you take DAPEFY 10MG TABLET 14'S twice a day?Arrow

Your doctor will decide the medicine's dose, strength, and frequency based on your blood sugar levels and other factors. Take DAPEFY 10MG TABLET 14'S as prescribed by your doctor.

How does DAPEFY 10MG TABLET 14'S help control blood sugar levels?Arrow

DAPEFY 10MG TABLET 14'S works by inhibiting glucose reabsorption in the kidneys, increasing glucose excretion in the urine, and lowering blood sugar levels. It helps to improve glycemic control in people with type 2 diabetes.

Can DAPEFY 10MG TABLET 14'S be used in people with kidney problems?Arrow

DAPEFY 10MG TABLET 14'S should be used with caution in individuals with kidney problems. The dose adjustments can be made based on kidney function. It is important to inform your physician about any existing kidney issues or changes in kidney function before taking this drug.

Does DAPEFY 10MG TABLET 14'S interact with other drugs?Arrow

No known interactions of DAPEFY 10MG TABLET 14'S with other drugs.

What advice should be followed while taking DAPEFY 10MG TABLET 14'S?Arrow

DAPEFY 10MG TABLET 14'S can increase urination, possibly leading to dehydration if not compensated for by adequate fluid intake. Drink plenty of water often to stay well hydrated. This drug causes genital yeast infections in both males and females. Practice good hygiene, including regular washing and cleaning of the genital area, to reduce the risk of infections. Limit the intake of sugary foods, processed snacks, and high-fat meals.

Which molecule/combination is used for making DAPEFY 10MG TABLET 14'S?Arrow

Dapagliflozin is the molecule/combination used for making DAPEFY 10MG TABLET 14'S.

For what ailments/diseases/conditions is DAPEFY 10MG TABLET 14'S prescribed?Arrow

DAPEFY 10MG TABLET 14'S is prescribed for the treatment of diabetes.

What is Dapefy 10 used for?Arrow

Dapefy 10 contains dapagliflozin 10 mg, an SGLT2 inhibitor used mainly to help control blood sugar levels in adults with type 2 diabetes mellitus, as part of a comprehensive treatment plan that includes diet and exercise. In some patients, dapagliflozin-based products may also be prescribed to reduce the risk of hospitalization for heart failure or to slow the progression of certain forms of chronic kidney disease, according to current clinical guidelines and the doctor’s judgment.

How does Dapefy 10 work in the body?Arrow

Dapefy 10 works by selectively blocking the SGLT2 protein in the kidneys, which is responsible for reabsorbing a large portion of filtered glucose back into the bloodstream. By inhibiting this transporter, more glucose is excreted in the urine, leading to a reduction in blood sugar levels. This mechanism is largely independent of insulin, which can be beneficial in patients with insulin resistance. The medicine may also contribute to modest weight loss and a small reduction in blood pressure in many patients.

Can Dapefy 10 be used in patients with liver problems?Arrow

In patients with mild to moderate liver impairment, dapagliflozin-containing medicines like Dapefy 10 may be used with caution, but the decision must be individualized by the treating physician. In severe liver disease, the safety profile is less well established, and alternative options may be preferred. Liver function tests and overall clinical status should be reviewed before starting therapy, and any symptoms such as persistent fatigue, loss of appetite, dark urine, or yellowing of the skin or eyes should be reported promptly.

Is Dapefy 10 safe for people with kidney disease?Arrow

Because Dapefy 10 acts on the kidneys, assessment of kidney function is essential before starting and during treatment. In patients with mild to moderate chronic kidney disease, dapagliflozin may still be used and can even provide renal and cardiovascular benefits in selected cases, according to evolving evidence and product labeling. However, in advanced kidney impairment or end-stage renal disease, the glucose-lowering effect is reduced and the medicine may not be appropriate. Only a doctor can decide whether it is suitable based on estimated glomerular filtration rate (eGFR) and overall clinical status.

Can I take Dapefy 10 during pregnancy?Arrow

Dapefy 10 is generally not recommended during pregnancy because data on the safety of dapagliflozin in pregnant women are limited, and animal studies have raised concerns about potential effects on kidney development in the fetus when exposure occurs during later stages of pregnancy. Women who are pregnant, planning to become pregnant, or who suspect they may be pregnant should inform their doctor before starting or continuing Dapefy 10. The doctor may switch to an alternative antidiabetic medicine with a better-established safety profile in pregnancy, such as insulin.

Is Dapefy 10 safe while breastfeeding?Arrow

The use of Dapefy 10 during breastfeeding is generally not advised because it is not known whether dapagliflozin passes into human breast milk, and there is a theoretical risk of affecting kidney development in a nursing infant. If blood sugar control is needed during lactation, the doctor will usually recommend alternative treatments with more established safety data. Mothers should discuss the risks and benefits with their healthcare provider and should not start or continue Dapefy 10 while breastfeeding without medical guidance.

Can I drive or operate machines while taking Dapefy 10?Arrow

Dapefy 10 itself does not usually cause drowsiness or directly impair concentration, so many patients can drive or operate machinery safely. However, when used in combination with other antidiabetic medicines that can cause low blood sugar, such as insulin or sulfonylureas, there is a risk of hypoglycemia, which may affect reaction time and alertness. Symptoms like dizziness, sweating, confusion, or blurred vision should be taken seriously. Patients should learn to recognize signs of low blood sugar and avoid driving if they feel unwell or if their blood glucose is very low.

Can I drink alcohol while taking Dapefy 10?Arrow

Moderate alcohol intake may be permissible for some patients on Dapefy 10, but it should be discussed with a healthcare professional. Excessive alcohol consumption can increase the risk of dehydration, low blood sugar (especially when combined with certain other diabetes medicines), and in rare cases may contribute to conditions like ketoacidosis. Because dapagliflozin increases urine output and can predispose to volume depletion, combining it with heavy alcohol use may increase the risk of dizziness, fainting, or kidney stress. Patients with liver disease, pancreatitis, or a history of alcohol misuse should be particularly cautious.

What should I do if I have allergies or had a reaction to similar medicines?Arrow

If you have a known allergy to dapagliflozin or any of the excipients in Dapefy 10, you should not take this medicine. Signs of an allergic reaction may include rash, itching, swelling of the face, lips, tongue, or throat, severe dizziness, or difficulty breathing. These symptoms require immediate medical attention. Before starting Dapefy 10, inform your doctor about any previous allergic reactions to SGLT2 inhibitors or other medicines, as well as any history of severe skin reactions or angioedema, so that an appropriate and safe treatment plan can be chosen.

Does Dapefy 10 cause low blood sugar (hypoglycemia)?Arrow

When used alone, Dapefy 10 has a relatively low risk of causing hypoglycemia because it works independently of insulin. However, the risk of low blood sugar increases when it is combined with other antidiabetic medicines that directly lower glucose, such as insulin or sulfonylureas. Symptoms of hypoglycemia include sweating, shakiness, hunger, palpitations, confusion, and in severe cases, loss of consciousness. Patients should follow their doctor’s instructions on blood sugar monitoring and may need dose adjustments of other diabetes medicines to reduce the risk of hypoglycemia.

What general precautions should I follow while taking Dapefy 10?Arrow

While taking Dapefy 10, maintain adequate hydration unless your doctor has advised fluid restriction, and monitor for signs of genital or urinary tract infections, such as itching, unusual discharge, pain, or burning during urination. Inform your doctor if you experience severe or persistent abdominal pain, nausea, vomiting, difficulty breathing, or extreme tiredness, as these could be signs of ketoacidosis or other serious conditions. Kidney function and, when appropriate, liver function should be checked periodically. Do not change the dose, stop the medicine, or start new medicines or herbal supplements without consulting your healthcare provider.

References

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AstraZeneca UK Limited, Electronic medicines compendium (EMC)

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Dapefy 10mg tablet- food and drug administration (FDA)

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AstraZeneca AB, European Medicines Agency (EMA)

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