DAPLO M 5MG TABLET 10'S
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DAPLO M 5MG TABLET 10'SDAPLO M 5MG TABLET 10'SDAPLO M 5MG TABLET 10'S
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DAPLO M 5MG TABLET 10'S

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DAPLO M 5MG TABLET 10'S

By DR REDDY'S LABORATORIES LIMITED

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169.25

₹143.86

15 % OFF

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About DAPLO M 5MG TABLET 10'S

  • DAPLO M 5MG TABLET 10'S is a combination medicine used to treat type 2 diabetes mellitus. It combines two powerful medications, Dapagliflozin and Metformin, to effectively control blood sugar levels. This medication is typically prescribed when diet and exercise alone are not sufficient to manage blood glucose effectively.
  • Dapagliflozin belongs to a class of drugs known as SGLT2 inhibitors (sodium-glucose cotransporter 2 inhibitors). It works by preventing the kidneys from reabsorbing glucose back into the blood. Instead, the excess glucose is eliminated from the body through urine, thereby lowering blood sugar levels. This mechanism also offers the added benefit of potential weight loss and blood pressure reduction.
  • Metformin, on the other hand, is a biguanide. It primarily works by decreasing glucose production in the liver and improving the body's sensitivity to insulin. Insulin is a hormone that helps glucose get from the blood into cells for energy. By making the body more responsive to insulin, metformin allows cells to utilize glucose more effectively, thus lowering blood sugar levels.
  • The combination of Dapagliflozin and Metformin in DAPLO M 5MG TABLET 10'S provides a dual approach to managing blood sugar. It addresses both the excess glucose production and impaired insulin sensitivity that are characteristic of type 2 diabetes. This synergistic effect often leads to better glycemic control compared to using either medication alone.
  • DAPLO M 5MG TABLET 10'S is usually taken once or twice daily with meals to minimize gastrointestinal side effects. Your doctor will determine the appropriate dosage based on your individual needs and response to treatment. It is crucial to follow your doctor's instructions carefully and to monitor your blood sugar levels regularly while taking this medication. Common side effects may include nausea, diarrhea, and abdominal discomfort. In rare cases, more serious side effects such as lactic acidosis (a buildup of lactic acid in the blood) can occur, especially in individuals with kidney problems. It's important to discuss any pre-existing medical conditions with your doctor before starting this medication.

Uses of DAPLO M 5MG TABLET 10'S

  • Treatment of type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Reducing the risk of heart disease (in diabetic patients)
  • Slowing the progression of kidney disease (in diabetic patients)
  • Assistance in weight management (in some patients)

How DAPLO M 5MG TABLET 10'S Works

  • DAPLO M 5MG TABLET 10'S is a combination medication containing Dapagliflozin and Metformin. It is primarily used to manage blood sugar levels in adults with type 2 diabetes mellitus, especially when diet and exercise alone are not sufficient. Each component of DAPLO M contributes uniquely to its overall effectiveness.
  • Dapagliflozin belongs to a class of drugs called Sodium-Glucose Co-Transporter 2 (SGLT2) inhibitors. SGLT2 is a protein in the kidneys that is responsible for reabsorbing glucose back into the bloodstream. Dapagliflozin works by blocking SGLT2, which reduces the reabsorption of glucose. As a result, excess glucose is excreted through the urine, thereby lowering blood sugar levels. This mechanism is dependent on kidney function and is more effective when kidney function is adequate. Additionally, the excretion of glucose through urine also leads to a slight caloric loss, which can contribute to weight loss in some individuals.
  • Metformin, on the other hand, is a biguanide and works through several different mechanisms. Primarily, it reduces glucose production in the liver by suppressing hepatic gluconeogenesis (the production of glucose from non-carbohydrate sources). Secondly, Metformin enhances insulin sensitivity in peripheral tissues such as muscle and fat, allowing cells to utilize glucose more effectively. This means that the body's cells are better able to respond to insulin and take up glucose from the bloodstream. Thirdly, Metformin slows down the absorption of glucose from the intestines after a meal, preventing sharp spikes in blood sugar levels.
  • The combination of Dapagliflozin and Metformin in DAPLO M provides a dual approach to managing blood sugar. Dapagliflozin helps to remove excess glucose from the body via the kidneys, while Metformin reduces glucose production in the liver and improves insulin sensitivity. This synergistic action results in more effective blood sugar control compared to using either medication alone. Patients taking DAPLO M typically experience improved HbA1c levels (a measure of long-term blood sugar control) and may also see benefits in terms of weight management and cardiovascular health.
  • It's important to note that DAPLO M is most effective when used in conjunction with a healthy diet and regular exercise. Patients should follow their doctor's recommendations regarding diet, exercise, and other lifestyle modifications to achieve the best possible outcomes. Regular monitoring of blood sugar levels and kidney function is also crucial while taking this medication to ensure safety and effectiveness.

Side Effects of DAPLO M 5MG TABLET 10'SArrow

Common side effects of DAPLO M 5MG TABLET may include: Nausea, Vomiting, Diarrhea, Abdominal pain, Loss of appetite, Metallic taste, Hypoglycemia (low blood sugar), Headache, Tremors, Dizziness, Weakness, Fatigue, Skin rash, Itching, Upper respiratory tract infection, Urinary tract infection, Increased thirst, Increased urination, Genital infections (in both men and women). Uncommon side effects may include: Ketoacidosis, Pancreatitis, Liver problems, Kidney problems, Dehydration, Angioedema (swelling under the skin).

Safety Advice for DAPLO M 5MG TABLET 10'SArrow

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Allergies

Allergies

Do not use DAPLO M 5MG TABLET 10'S if you are allergic to it.

Dosage of DAPLO M 5MG TABLET 10'SArrow

  • The recommended dosage of DAPLO M 5MG TABLET 10'S' varies depending on the individual's condition, renal function, and other medications they may be taking. It's crucial to adhere to your doctor's specific instructions regarding dosage and timing. Generally, the starting dose is typically one tablet daily, taken orally. Your doctor may adjust the dosage based on your response to the treatment and tolerance of the medication. It can be taken with or without food, but it is recommended to take it at the same time each day to maintain consistent blood levels of the medication.
  • If you miss a dose of DAPLO M 5MG TABLET 10'S', take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. This medication is most effective when taken consistently as prescribed. Changes to your diet or exercise regimen can also affect the medication's effectiveness, so maintaining a stable lifestyle is advisable. Regular monitoring of blood sugar levels and kidney function may be necessary while taking DAPLO M 5MG TABLET 10'S'.
  • It is very important to follow all the instructions of your health care provider. Do not change the dosage yourself. Take 'DAPLO M 5MG TABLET 10'S' only as per the prescription by your physician only.

What if I miss my dose of DAPLO M 5MG TABLET 10'S?Arrow

  • If you miss a dose of DAPLO M 5MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

How to store DAPLO M 5MG TABLET 10'S?Arrow

  • Keep DAPLO M 5MG TAB 1X10 away from the reach of children and pets.
  • Store DAPLO M 5MG TAB 1X10 at room temperature.

Benefits of DAPLO M 5MG TABLET 10'SArrow

  • DAPLO M 5MG TABLET 10'S is a combination medicine used to treat type 2 diabetes mellitus. It combines dapagliflozin and metformin to effectively control blood sugar levels. Dapagliflozin belongs to a class of drugs called sodium-glucose co-transporter 2 (SGLT2) inhibitors, while metformin is a biguanide. This dual action helps manage diabetes through different mechanisms.
  • One of the primary benefits of DAPLO M 5MG TABLET 10'S is its ability to lower blood sugar levels. Dapagliflozin works by preventing the kidneys from reabsorbing glucose back into the blood. Instead, the excess glucose is excreted through urine, thus reducing blood sugar levels. Metformin, on the other hand, reduces glucose production in the liver and improves insulin sensitivity, allowing the body to use insulin more effectively.
  • Improved glycemic control offered by DAPLO M 5MG TABLET 10'S can lead to a reduced risk of diabetes-related complications. High blood sugar levels over a prolonged period can damage various organs, leading to heart disease, kidney disease, nerve damage (neuropathy), and eye damage (retinopathy). By effectively managing blood sugar, this medication helps protect against these long-term complications, improving overall health and quality of life.
  • DAPLO M 5MG TABLET 10'S may also contribute to weight loss. Dapagliflozin's mechanism of action involves excreting excess glucose through urine, which results in a loss of calories. This can lead to modest weight loss in some individuals, which is particularly beneficial for those with type 2 diabetes who are often overweight or obese. Weight management is an important aspect of diabetes control, as it can improve insulin sensitivity and reduce the risk of cardiovascular problems.
  • Furthermore, DAPLO M 5MG TABLET 10'S has shown cardiovascular benefits in clinical trials. Dapagliflozin has been found to reduce the risk of heart failure and cardiovascular death in patients with type 2 diabetes who have established cardiovascular disease or multiple cardiovascular risk factors. This makes it a valuable option for individuals who are at high risk of heart problems.
  • DAPLO M 5MG TABLET 10'S can also improve blood pressure. Studies have shown that dapagliflozin can lead to a slight reduction in blood pressure, which is an added benefit for individuals with diabetes who often have co-existing hypertension. Managing blood pressure is crucial in reducing the risk of cardiovascular events.
  • Another significant advantage of DAPLO M 5MG TABLET 10'S is its convenience. As a combination medicine, it simplifies the treatment regimen by combining two medications into a single tablet. This can improve adherence to the prescribed treatment plan, as patients only need to take one pill instead of multiple ones. Improved adherence leads to better blood sugar control and overall health outcomes.
  • In addition to its direct effects on blood sugar and cardiovascular health, DAPLO M 5MG TABLET 10'S can also have a positive impact on kidney health. Dapagliflozin has been shown to slow the progression of kidney disease in individuals with type 2 diabetes and kidney problems. This protective effect on the kidneys is particularly important, as diabetes is a leading cause of chronic kidney disease.
  • DAPLO M 5MG TABLET 10'S offers a comprehensive approach to managing type 2 diabetes by addressing multiple aspects of the disease. It not only controls blood sugar levels but also provides cardiovascular and renal benefits, contributing to a healthier and longer life for individuals with diabetes.

How to use DAPLO M 5MG TABLET 10'SArrow

  • DAPLO M 5MG TABLET 10'S is an oral medication primarily prescribed for individuals managing type 2 diabetes. To maximize its effectiveness and minimize potential side effects, it's crucial to adhere to your doctor's instructions regarding dosage and timing. Typically, it is recommended to take DAPLO M once daily, preferably in the morning with food. This helps to reduce the likelihood of stomach upset and also aligns with the body's natural metabolic processes throughout the day.
  • Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this can affect how the medication is released into your system. Consistency is key when taking DAPLO M. Try to take it at the same time each day to maintain a steady level of medication in your bloodstream. If you miss a dose, take it as soon as you remember, unless it's almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
  • DAPLO M works best when combined with a healthy diet and regular exercise. Continue to follow any dietary and exercise recommendations provided by your healthcare provider. It's also important to monitor your blood sugar levels regularly, as directed by your doctor. This will help you track how well the medication is working and make any necessary adjustments to your treatment plan. Keep all your scheduled appointments with your doctor and lab for regular check-ups and monitoring. Inform your doctor about any other medications, supplements, or herbal products you are taking, as they may interact with DAPLO M. Be aware of potential side effects, such as nausea, diarrhea, or headache, and report any persistent or severe side effects to your doctor promptly.
  • Store DAPLO M at room temperature, away from moisture and heat. Keep it out of reach of children. Always consult your doctor or pharmacist if you have any questions or concerns about taking DAPLO M.

Quick Tips for DAPLO M 5MG TABLET 10'SArrow

  • Take DAPLO M 5MG TABLET 10'S exactly as prescribed by your doctor. Do not change the dosage or stop taking the medication without consulting them. This helps maintain consistent blood sugar control and avoids potential complications.
  • It is best to take DAPLO M 5MG TABLET 10'S at the same time each day, preferably with your first main meal. This routine helps you remember to take it and ensures optimal absorption and effectiveness throughout the day. Consistency is key for managing your blood sugar levels effectively.
  • DAPLO M 5MG TABLET 10'S works best when combined with a healthy diet and regular exercise. Focus on incorporating balanced meals, low in sugars and saturated fats, along with at least 30 minutes of moderate-intensity exercise most days of the week. This lifestyle approach significantly improves blood sugar control and overall health.
  • Monitor your blood sugar levels regularly as directed by your healthcare provider while taking DAPLO M 5MG TABLET 10'S. Keeping track of your blood sugar readings helps you and your doctor assess how well the medication is working and make any necessary adjustments to your treatment plan. It also helps you identify any potential issues early on.
  • Stay well-hydrated by drinking plenty of water throughout the day. Adequate hydration supports kidney function and can help prevent complications associated with diabetes. Aim for at least 8 glasses of water daily, unless your doctor advises otherwise.
  • Be aware of the symptoms of low blood sugar (hypoglycemia), such as sweating, shaking, dizziness, and confusion. If you experience these symptoms, consume a quick source of sugar, such as glucose tablets or fruit juice, and inform your doctor immediately. Carry a readily available source of sugar with you at all times.
  • Inform your doctor about all other medications, supplements, and herbal remedies you are taking before starting DAPLO M 5MG TABLET 10'S. Some medications can interact with this medicine, affecting its effectiveness or increasing the risk of side effects. A complete medication list ensures your doctor can make informed decisions about your treatment.
  • Attend all scheduled doctor's appointments and lab tests. Regular check-ups and blood tests are crucial for monitoring your overall health and the effectiveness of DAPLO M 5MG TABLET 10'S. These appointments allow your doctor to identify any potential problems early and adjust your treatment plan accordingly.
  • Store DAPLO M 5MG TABLET 10'S in a cool, dry place away from direct sunlight and moisture. Proper storage ensures the medication remains effective and safe to use. Keep it out of reach of children and pets.
  • If you experience any persistent or bothersome side effects while taking DAPLO M 5MG TABLET 10'S, such as nausea, diarrhea, or skin rash, contact your doctor promptly. They can assess the situation and provide appropriate guidance or adjust your treatment plan if necessary.

FAQs

What is DAPLO M 5MG TABLET 10'S?Arrow

DAPLO M 5MG TABLET 10'S is a combination of two medicines: Dapagliflozin and Metformin. It is used to treat type 2 diabetes mellitus.

What is DAPLO M 5MG TABLET 10'S used for?Arrow

DAPLO M 5MG TABLET 10'S is used to control blood sugar levels in adults with type 2 diabetes mellitus when diet and exercise are not enough.

How does DAPLO M 5MG TABLET 10'S work?Arrow

Dapagliflozin works by reducing the reabsorption of glucose from the kidneys, leading to more glucose being excreted in the urine. Metformin works by decreasing the amount of glucose produced by the liver and improving the body's sensitivity to insulin.

What are the common side effects of DAPLO M 5MG TABLET 10'S?Arrow

Common side effects of DAPLO M 5MG TABLET 10'S include nausea, vomiting, diarrhea, abdominal pain, and headache.

Is DAPLO M 5MG TABLET 10'S harmful to the kidneys?Arrow

DAPLO M 5MG TABLET 10'S can worsen kidney problems in people with existing kidney issues. It is not recommended for use in people with severe kidney disease.

Does DAPLO M 5MG TABLET 10'S cause weight loss?Arrow

DAPLO M 5MG TABLET 10'S may cause weight loss in some people, but this is not its primary use.

Is DAPLO M 5MG TABLET 10'S safe?Arrow

DAPLO M 5MG TABLET 10'S is safe for most people when taken as prescribed by a doctor. Talk to your doctor if you have any concerns.

How to store DAPLO M 5MG TABLET 10'S?Arrow

Store DAPLO M 5MG TABLET 10'S at room temperature, away from direct sunlight and moisture.

Should DAPLO M 5MG TABLET 10'S be taken with food?Arrow

DAPLO M 5MG TABLET 10'S can be taken with or without food, but it is best to take it at the same time each day.

What happens if I miss a dose of DAPLO M 5MG TABLET 10'S?Arrow

If you miss a dose of DAPLO M 5MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Is DAPLO M 5MG TABLET 10'S safe during pregnancy?Arrow

The safety of DAPLO M 5MG TABLET 10'S during pregnancy has not been established. It should only be used if clearly needed and directed by a doctor.

Is DAPLO M 5MG TABLET 10'S safe during breastfeeding?Arrow

It is not known whether DAPLO M 5MG TABLET 10'S passes into breast milk. Consult your doctor before using it while breastfeeding.

Can I drink alcohol with DAPLO M 5MG TABLET 10'S?Arrow

It is not recommended to consume alcohol while taking DAPLO M 5MG TABLET 10'S, as it can increase the risk of low blood sugar (hypoglycemia).

What happens if I overdose on DAPLO M 5MG TABLET 10'S?Arrow

If you overdose on DAPLO M 5MG TABLET 10'S, seek immediate medical attention. Symptoms of an overdose may include nausea, vomiting, abdominal pain, and weakness.

Does DAPLO M 5MG TABLET 10'S interact with other medications?Arrow

DAPLO M 5MG TABLET 10'S can interact with certain other medications, such as insulin and certain diuretics. Tell your doctor about all medications you are taking.

References

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FDA - FARXIGA (dapagliflozin) tablets, for oral use. Full prescribing information including warnings, contraindications, adverse reactions, and dosage/administration.

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DrugBank - Dapagliflozin: Comprehensive information including mechanism of action, metabolism, and drug interactions.

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PubMed Central - Dapagliflozin: A review of its pharmacology, therapeutic use and safety

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European Medicines Agency (EMA) - Farxiga: European public assessment report.

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UpToDate - Dapagliflozin: Drug information (requires subscription).

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ScienceDirect - Dapagliflozin - an overview of its pharmacology and clinical applications.

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Journal of the American Heart Association - Dapagliflozin and Cardiovascular Outcomes in Type 2 Diabetes

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Diabetes Care - Dapagliflozin in Patients with Type 2 Diabetes Mellitus Treated With Insulin: Effects on Glycemic Control and Insulin Dose

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Sodium-glucose co-transporter 2 (SGLT2) inhibitors: potential benefits and risks

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