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JUSTOZA M 5/500MG TABLET 10'S

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JUSTOZA M 5/500MG TABLET 10'S

By MANKIND PHARMA LIMITED

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₹65.45

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About JUSTOZA M 5/500MG TABLET 10'S

  • JUSTOZA M 5/500MG TABLET is a combination medicine used to treat type 2 diabetes mellitus. It improves blood sugar control in adults when used along with diet and exercise. This medication contains two active ingredients: Metformin and Teneligliptin.
  • Metformin is a biguanide that works by decreasing glucose production in the liver and improving insulin sensitivity, allowing the body to use insulin more effectively. It also reduces the amount of glucose absorbed from the intestines.
  • Teneligliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. It works by increasing the release of insulin from the pancreas and decreasing the hormones that raise blood sugar levels. By enhancing insulin secretion and suppressing glucagon, teneligliptin helps to regulate blood glucose levels after meals.
  • JUSTOZA M is typically taken orally, usually once or twice daily, with meals to minimize gastrointestinal side effects. The dosage is determined by your doctor based on your medical condition, blood sugar levels, and response to treatment. It is important to take JUSTOZA M exactly as prescribed by your doctor to achieve the best possible results.
  • Common side effects of JUSTOZA M may include nausea, vomiting, diarrhea, abdominal pain, and loss of appetite. These side effects are usually mild and temporary. However, if you experience any severe or persistent side effects, such as lactic acidosis (a buildup of lactic acid in the blood), it is essential to seek immediate medical attention.
  • Before taking JUSTOZA M, inform your doctor about your medical history, especially if you have kidney or liver disease, heart problems, or a history of pancreatitis. Also, tell your doctor about all the other medications you are taking, including prescription and over-the-counter drugs, vitamins, and herbal supplements. This is to avoid any potential drug interactions.
  • JUSTOZA M is a valuable tool in managing type 2 diabetes, but it should be used in conjunction with a healthy lifestyle, including a balanced diet and regular exercise. Regular monitoring of blood sugar levels is crucial to ensure that the medication is working effectively and to adjust the dosage as needed. Always consult with your healthcare provider for personalized advice and treatment options.

Uses of JUSTOZA M 5/500MG TABLET 10'S

  • Treatment of type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Improving insulin sensitivity
  • Managing insulin resistance associated with polycystic ovary syndrome (PCOS)
  • Reducing the risk of cardiovascular disease in patients with type 2 diabetes
  • Used in combination with diet and exercise
  • May be used in combination with other diabetes medications

How JUSTOZA M 5/500MG TABLET 10'S Works

  • JUSTOZA M 5/500MG TABLET is a combination medication containing Metformin and Sitagliptin, designed to manage blood sugar levels in individuals with type 2 diabetes. It works through complementary mechanisms to achieve optimal glycemic control.
  • Metformin, a biguanide, primarily reduces glucose production in the liver. It achieves this by suppressing hepatic gluconeogenesis, the process by which the liver creates glucose from non-carbohydrate sources. Additionally, Metformin enhances insulin sensitivity in peripheral tissues, such as muscles, allowing them to utilize glucose more effectively. It also slows down the absorption of glucose from the intestines, further contributing to lower blood sugar levels after meals. Metformin's action doesn't typically cause hypoglycemia (low blood sugar) when used alone, but it can when combined with other diabetes medications.
  • Sitagliptin, a DPP-4 inhibitor, works by increasing the levels of incretin hormones in the body. Incretins are naturally produced hormones that stimulate insulin release from the pancreas when blood sugar levels are high and suppress glucagon secretion (a hormone that raises blood sugar) after a meal. By inhibiting DPP-4, an enzyme that breaks down incretins, Sitagliptin prolongs the action of these hormones, leading to improved blood sugar control. Specifically, Sitagliptin helps to increase insulin release in response to elevated blood glucose, while simultaneously reducing glucagon secretion, which further lowers blood sugar levels.
  • The synergistic effect of Metformin and Sitagliptin in JUSTOZA M allows for comprehensive management of blood sugar. Metformin addresses insulin resistance and excessive glucose production, while Sitagliptin enhances the body's natural ability to regulate glucose levels through incretin hormones. Together, they provide a balanced approach to controlling blood sugar in patients with type 2 diabetes, helping to maintain stable glucose levels throughout the day.
  • It is crucial to take JUSTOZA M as prescribed by your doctor and to follow their recommendations regarding diet and exercise. This medication is most effective when combined with a healthy lifestyle. Regular monitoring of blood sugar levels is also important to assess the effectiveness of the treatment and make any necessary adjustments.

Side Effects of JUSTOZA M 5/500MG TABLET 10'SArrow

Possible side effects of JUSTOZA M 5/500MG TABLET may include nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, hypoglycemia (low blood sugar), headache, dizziness, fatigue, weakness, skin rash, itching, and rarely, lactic acidosis. Consult your doctor if you experience any persistent or severe side effects.

Safety Advice for JUSTOZA M 5/500MG TABLET 10'SArrow

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Allergies

Allergies

Caution if you have allergies; consult your doctor.

Dosage of JUSTOZA M 5/500MG TABLET 10'SArrow

  • The recommended dosage of JUSTOZA M 5/500MG TABLET 10'S is typically determined by your physician based on individual needs, blood glucose levels, and response to treatment. It is crucial to adhere strictly to the prescribed dosage and schedule. Generally, it is taken orally, usually once or twice daily, with meals to minimize potential gastrointestinal side effects. The specific dosage may vary depending on whether you are already taking other diabetes medications.
  • For individuals new to this medication, the starting dose may be lower, gradually increasing as needed to achieve optimal glycemic control. Regular monitoring of blood glucose levels is essential to guide dosage adjustments. Your doctor will likely monitor your HbA1c levels periodically to assess long-term blood sugar control and make necessary adjustments to your treatment plan. Do not change the dosage on your own without consulting your healthcare provider.
  • If you miss a dose of JUSTOZA M 5/500MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this can increase the risk of side effects. It's important to maintain consistency in taking the medication at the same time(s) each day to help maintain stable blood glucose levels.
  • Take 'JUSTOZA M 5/500MG TABLET 10'S' only as per the prescription by your physician only. It is important to follow your doctor's instructions precisely and to attend all scheduled follow-up appointments. This will allow your doctor to monitor your progress, assess the effectiveness of the medication, and make any necessary adjustments to your treatment plan. Proper diet and exercise are also essential components of managing diabetes effectively. Discuss your diet and exercise plan with your doctor or a registered dietitian.

What if I miss my dose of JUSTOZA M 5/500MG TABLET 10'S?Arrow

  • If you miss a dose of JUSTOZA M 5/500MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to catch up.

How to store JUSTOZA M 5/500MG TABLET 10'S?Arrow

  • Keep JUSTOZA M 5/500MG TAB 1X10 away from the reach of children and pets.
  • Store JUSTOZA M 5/500MG TAB 1X10 at room temperature.

Benefits of JUSTOZA M 5/500MG TABLET 10'SArrow

  • JUSTOZA M 5/500MG TABLET 10'S is a combination medicine used to effectively manage type 2 diabetes mellitus. It combines two powerful antidiabetic drugs, sitagliptin and metformin, to provide comprehensive glycemic control. By taking JUSTOZA M 5/500MG TABLET 10'S as prescribed by your doctor, you can significantly improve your blood sugar levels and reduce the risk of long-term complications associated with diabetes.
  • Sitagliptin, one of the active ingredients in JUSTOZA M 5/500MG TABLET 10'S, belongs to a class of drugs called DPP-4 inhibitors. It works by increasing the levels of incretin hormones in the body. These hormones help to regulate blood sugar by stimulating the release of insulin after meals and decreasing the amount of glucose produced by the liver. By enhancing the action of incretin hormones, sitagliptin helps to improve insulin sensitivity and lower blood sugar levels, particularly after eating.
  • Metformin, the other key component of JUSTOZA M 5/500MG TABLET 10'S, is a biguanide that works primarily by reducing glucose production in the liver and improving the body's response to insulin. It also helps to decrease the absorption of glucose from the intestines. Metformin is a well-established and widely used medication for type 2 diabetes, known for its effectiveness in lowering blood sugar levels and its potential to promote modest weight loss in some individuals.
  • The combined action of sitagliptin and metformin in JUSTOZA M 5/500MG TABLET 10'S offers several advantages in managing type 2 diabetes. Firstly, it provides a dual mechanism of action, addressing different aspects of glucose regulation. Sitagliptin enhances insulin secretion and reduces glucose production, while metformin reduces hepatic glucose output and improves insulin sensitivity. This synergistic effect can lead to better glycemic control compared to using either drug alone.
  • Secondly, JUSTOZA M 5/500MG TABLET 10'S is convenient to use as it combines two medications into a single tablet, simplifying the treatment regimen and improving patient adherence. This can be particularly beneficial for individuals who are already taking multiple medications for other health conditions.
  • Thirdly, JUSTOZA M 5/500MG TABLET 10'S has been shown to be effective in lowering HbA1c levels, a measure of average blood sugar control over the past 2-3 months. By consistently taking JUSTOZA M 5/500MG TABLET 10'S as directed, you can achieve and maintain better long-term glycemic control, which is crucial for preventing diabetes-related complications such as heart disease, kidney disease, nerve damage, and vision problems.
  • Finally, JUSTOZA M 5/500MG TABLET 10'S is generally well-tolerated, with most side effects being mild and temporary. Common side effects may include nausea, diarrhea, and abdominal discomfort. However, it is important to discuss any concerns or potential side effects with your doctor. In rare cases, metformin can cause a serious side effect called lactic acidosis, so it is important to be aware of the symptoms and seek medical attention immediately if they occur. By working closely with your doctor and following their instructions carefully, you can maximize the benefits of JUSTOZA M 5/500MG TABLET 10'S and effectively manage your type 2 diabetes.

How to use JUSTOZA M 5/500MG TABLET 10'SArrow

  • JUSTOZA M 5/500MG TABLET 10'S is a combination medicine used to treat type 2 diabetes mellitus. It contains Metformin and Sitagliptin as active ingredients. This medication works best when taken consistently as directed by your doctor. Always follow their specific instructions regarding dosage and timing.
  • The usual starting dose is one tablet taken orally once or twice daily, typically with meals. Taking it with food helps to reduce the risk of stomach upset, a common side effect of Metformin. Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet, as this can affect how the medication is released and absorbed into your body.
  • It's crucial to take JUSTOZA M 5/500MG TABLET 10'S at the same time(s) each day to maintain a consistent level of medication in your bloodstream. This helps to control your blood sugar levels more effectively. If you miss a dose, take it as soon as you remember, unless it's almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.
  • Your doctor may adjust your dose of JUSTOZA M 5/500MG TABLET 10'S based on your blood sugar levels and how well you tolerate the medication. It's important to attend all scheduled follow-up appointments with your doctor so they can monitor your progress and make any necessary adjustments to your treatment plan. Do not change your dose or stop taking this medication without consulting your doctor first.
  • In addition to taking JUSTOZA M 5/500MG TABLET 10'S, it's important to follow a healthy diet and exercise regularly. These lifestyle modifications can help to improve your blood sugar control and overall health. Be sure to talk to your doctor or a registered dietitian about creating a diabetes management plan that's right for you.
  • Before starting JUSTOZA M 5/500MG TABLET 10'S, inform your doctor about any other medical conditions you have, especially kidney or liver disease, heart problems, or a history of pancreatitis. Also, tell your doctor about all the medications you are taking, including prescription drugs, over-the-counter medications, and herbal supplements.
  • Regular monitoring of your blood sugar levels is essential while taking this medication. Your doctor may also recommend periodic blood tests to check your kidney function and other parameters. Contact your doctor immediately if you experience any unusual side effects, such as severe abdominal pain, nausea, vomiting, or persistent fatigue.

Quick Tips for JUSTOZA M 5/500MG TABLET 10'SArrow

  • Take JUSTOZA M 5/500MG TABLET 10'S as prescribed by your doctor. Do not self-medicate or change the dosage without consulting your healthcare provider. It's crucial to adhere to their instructions for optimal results and to minimize potential side effects. Always complete the full course of treatment, even if you feel better, to ensure the medication effectively manages your condition and prevents recurrence.
  • To minimize stomach upset, take JUSTOZA M 5/500MG TABLET 10'S with food. This can help reduce nausea, indigestion, or other gastrointestinal discomfort that some individuals may experience. Consuming the tablet with a meal also aids in consistent absorption of the medication into your bloodstream, contributing to its overall effectiveness throughout the day.
  • Monitor your blood sugar levels regularly while taking JUSTOZA M 5/500MG TABLET 10'S, especially if you have diabetes. This medication can impact your blood sugar control, so frequent monitoring helps you and your doctor adjust your treatment plan as needed. Keep a log of your readings to share with your healthcare provider during check-ups, allowing for informed decisions about your health management.
  • Be aware of potential side effects of JUSTOZA M 5/500MG TABLET 10'S, such as hypoglycemia (low blood sugar). Watch out for symptoms like dizziness, sweating, shakiness, or confusion. If you experience any of these, consume a fast-acting source of sugar, like juice or hard candy, and inform your doctor promptly. Understanding potential side effects empowers you to take quick action and prevent complications.
  • Inform your doctor about all other medications, supplements, and herbal products you are taking before starting JUSTOZA M 5/500MG TABLET 10'S. Drug interactions can occur, affecting how the medication works or increasing the risk of side effects. Providing a comprehensive list of everything you're taking ensures your doctor can safely manage your treatment and avoid potential conflicts.
  • Maintain a healthy lifestyle while taking JUSTOZA M 5/500MG TABLET 10'S by following a balanced diet and exercising regularly. These habits can significantly improve your overall health and complement the effects of the medication. Consult with a healthcare professional or registered dietitian for personalized guidance on nutrition and exercise strategies that align with your health needs.
  • Store JUSTOZA M 5/500MG TABLET 10'S in a cool, dry place away from direct sunlight and moisture. Proper storage is essential for maintaining the medication's potency and effectiveness. Keep it out of reach of children and pets to prevent accidental ingestion. Avoid storing it in the bathroom, as the humidity can degrade the medication over time.

Food Interactions with JUSTOZA M 5/500MG TABLET 10'SArrow

  • JUSTOZA M 5/500MG TABLET 10'S can be taken with or without food, but it is generally recommended to take it with food to minimize the risk of gastrointestinal side effects such as nausea or stomach upset. Consistent timing with meals can also help maintain stable blood sugar levels.

FAQs

What is Justoza M 5/500mg Tablet 10'S?Arrow

Justoza M 5/500mg Tablet 10'S is a combination of two medicines: Dapagliflozin and Metformin. It is used to control high blood sugar levels in adults with type 2 diabetes mellitus.

How to use Justoza M 5/500mg Tablet 10'S?Arrow

Take Justoza M 5/500mg Tablet 10'S as prescribed by your doctor. Take it with food and swallow the tablet whole. Do not crush, chew or break it.

What are the common side effects of Justoza M 5/500mg Tablet 10'S?Arrow

The common side effects of Justoza M 5/500mg Tablet 10'S include nausea, vomiting, diarrhea, abdominal pain, and loss of appetite.

Is Justoza M 5/500mg Tablet 10'S safe for kidneys?Arrow

Justoza M 5/500mg Tablet 10'S should be used with caution in patients with kidney disease. Dose adjustment may be needed, so consult your doctor.

How to store Justoza M 5/500mg Tablet 10'S?Arrow

Store Justoza M 5/500mg Tablet 10'S at room temperature, away from direct sunlight and heat. Keep it out of reach of children and pets.

Is Justoza M 5/500mg Tablet 10'S safe during pregnancy?Arrow

The safety of Justoza M 5/500mg Tablet 10'S during pregnancy is not established. Therefore, consult your doctor before using it during pregnancy.

Is Justoza M 5/500mg Tablet 10'S safe for breastfeeding mothers?Arrow

The safety of Justoza M 5/500mg Tablet 10'S for breastfeeding mothers is not established. Therefore, consult your doctor before using it during breastfeeding.

What if I miss a dose of Justoza M 5/500mg Tablet 10'S?Arrow

If you miss a dose of Justoza M 5/500mg Tablet 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose.

Is it safe to drink alcohol with Justoza M 5/500mg Tablet 10'S?Arrow

It is not recommended to drink alcohol with Justoza M 5/500mg Tablet 10'S as it can lower blood sugar levels and cause other side effects.

Does Justoza M 5/500mg Tablet 10'S cause weight loss?Arrow

Justoza M 5/500mg Tablet 10'S may cause weight loss in some patients, but it is not for everyone.

What to do in case of an overdose of Justoza M 5/500mg Tablet 10'S?Arrow

If you think you have taken an overdose of Justoza M 5/500mg Tablet 10'S, contact your doctor or the nearest hospital immediately.

Does Justoza M 5/500mg Tablet 10'S interact with other medications?Arrow

Justoza M 5/500mg Tablet 10'S can interact with certain medications. Therefore, tell your doctor about all the medications you are taking, including prescription and non-prescription drugs, vitamins, and herbal supplements.

Can I take Justoza M 5/500mg Tablet 10'S with other diabetes medications?Arrow

Consult your doctor before taking Justoza M 5/500mg Tablet 10'S with other diabetes medications as it can cause a very low blood sugar level (hypoglycemia).

Are there any special precautions I should take while taking Justoza M 5/500mg Tablet 10'S?Arrow

While taking Justoza M 5/500mg Tablet 10'S, monitor your blood sugar levels regularly, eat a healthy diet, and exercise regularly. Drink plenty of fluids to avoid dehydration.

How long does it take for Justoza M 5/500mg Tablet 10'S to start working?Arrow

It may take a few days for Justoza M 5/500mg Tablet 10'S to start working. Continue to take it as directed to see the maximum benefits.

References

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DrugBank: Metformin and Sitagliptin Combination

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FDA Label: JANUMET (sitagliptin and metformin hydrochloride) tablets

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European Medicines Agency (EMA): Janumet (sitagliptin / metformin)

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National Center for Biotechnology Information (NCBI): Efficacy and safety of sitagliptin added to metformin in Japanese patients with type 2 diabetes

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National Center for Biotechnology Information (NCBI): Sitagliptin/metformin fixed-dose combination: a practical option for the treatment of type 2 diabetes

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JANUMET® (sitagliptin and metformin HCl) Tablets Prescribing Information

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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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