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DARB-ESA 40 INJECTION
DARB-ESA 40 INJECTION
By SEPTALYST LIFESCIENCES PVT LTD
MRP
₹
2499
₹2124.15
15 % OFF
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Composition
Product Details
About DARB-ESA 40 INJECTION
- DARB-ESA 40 INJECTION is an antineoplastic medication that belongs to a class of drugs known as hematopoietic growth factors. It contains the active compound Darbepoetin Alfa. It is used to treat anemia in people with chronic kidney disease and anemia caused by chemotherapy in people with certain types of cancer. DARB-ESA 40 INJECTION stimulates the bone marrow to produce more red blood cells, helping to alleviate the symptoms of anemia such as fatigue and weakness. This medication is often prescribed when the body is not producing enough red blood cells on its own, ensuring adequate oxygen delivery to tissues and organs.
- It is not recommended to take Darbepoetin alfa if you are allergic to active compounds or any other ingredients of this medicine. It is recommended to monitor complete blood count before starting the therapy. It is not recommended for use in patients who have uncontrolled blood pressure. It is not recommended for use in patients who receive cancer treatment with hormonal drugs and radiotherapy. It is not advised to be used in place of red blood cell transfusions in individuals in need of immediate anemia correction. Inform your physician if you have high blood pressure, anemia, a history of seizures, epilepsy, liver disease, or allergy to latex or hepatitis C. Inform your physician if you are pregnant or breastfeeding.
- Before initiating the treatment, inform your physician if you have fever, blood clots, any infections, kidney, heart or liver problems. Your doctor will monitor your haemoglobin levels to ensure they stay within a specified range. High haemoglobin concentrations can increase your chance of developing heart or blood vessel problems. It is necessary to inform your physician about all the medicines, over the counter drugs, vitamin and herbal supplements you are taking before the start of therapy. Regular monitoring by your healthcare provider is crucial to ensure the effectiveness and safety of the treatment. They will adjust the dosage as needed based on your individual response and overall health condition. Adhering to your doctor's instructions and attending all scheduled appointments are essential for optimal outcomes.
Uses of DARB-ESA 40 INJECTION
- To manage anemia associated with chronic kidney failure by stimulating red blood cell production.
- To address anemia resulting from chemotherapy treatments by boosting red blood cell levels.
Side Effects of DARB-ESA 40 INJECTION
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them.
- Swelling in the face and body
- Low blood pressure
- Abdominal pain
- Shortness of breath
- cough
- Heart problems
- Severe skin reactions
- Anemia
- Seizure attack
- Lung problems
Safety Advice for DARB-ESA 40 INJECTION

Pregnancy
CONSULT YOUR DOCTORThere are no adequate and well-controlled studies on the use of DARB-ESA 40 INJECTION in pregnant women. Inform your physician if you are pregnant, suspecting, or planning for pregnancy during the treatment.
Dosage of DARB-ESA 40 INJECTION
- DARB-ESA 40 INJECTION is administered subcutaneously, meaning it's injected beneath the skin. Your healthcare provider will give you detailed instructions on how to use the pre-filled pen for self-injection. It's crucial to receive proper training before attempting to self-inject. If you're not adequately trained, please do not attempt the injection.
- Never administer this medication intravenously (directly into a vein). If you require assistance with administering DARB-ESA 40 INJECTION, please visit your local hospital or clinic. A healthcare professional can ensure the injection is given correctly and safely.
- The dosage and frequency of DARB-ESA 40 INJECTION depend on several factors, including your age, weight, overall health, and the specific condition being treated. It is essential to strictly adhere to the dosage instructions provided by your doctor or healthcare provider. Do not alter the dosage or frequency of injections without first consulting with them.
- Missing a dose of DARB-ESA 40 INJECTION should be addressed promptly. If you miss a dose, administer it as soon as you remember, unless it's within 6 hours of your next scheduled dose. If it's close to your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to compensate for the missed injection.
- Proper storage of DARB-ESA 40 INJECTION is crucial to maintain its effectiveness. Store the pre-filled pens in the refrigerator, protected from light. Do not freeze. Before injecting, allow the pen to reach room temperature as instructed by your healthcare provider. Always check the expiration date before use, and discard any expired medication properly, following local regulations.
How to store DARB-ESA 40 INJECTION?
- Keep DARB-ESA 40MCG INJ 0.4ML away from the reach of children and pets.
- Store DARB-ESA 40MCG INJ 0.4ML in a refrigerator (2 - 8°C). Do not freeze.
Benefits of DARB-ESA 40 INJECTION
- DARB-ESA 40 INJECTION is a synthetically produced erythropoiesis-stimulating agent (ESA). It is created using recombinant DNA technology to mimic the action of erythropoietin, a natural hormone produced by the kidneys. This medication plays a vital role in managing anemia, particularly in patients with chronic kidney disease or those undergoing chemotherapy. When DARB-ESA 40 INJECTION enters the body, it seeks out and binds to erythropoietin receptors located on the surface of erythroid progenitor cells within the bone marrow. This binding triggers a cascade of intracellular signals.
- This signaling cascade is crucial for the survival, proliferation, and differentiation of these erythroid progenitor cells. Essentially, DARB-ESA 40 INJECTION enhances the bone marrow's ability to produce red blood cells. By increasing the number of red blood cells, the medication helps to improve oxygen delivery throughout the body, alleviating the symptoms of anemia such as fatigue and shortness of breath.
- The activation of erythropoietin receptors stimulates the development of red blood cells, leading to an overall increase in red blood cell production. This mechanism is particularly beneficial for individuals whose bodies are not producing enough erythropoietin naturally, such as those with kidney disease. DARB-ESA 40 INJECTION is, therefore, a key medication for managing anemia and improving the quality of life for affected individuals.
How to use DARB-ESA 40 INJECTION
- DARB-ESA 40 INJECTION is administered subcutaneously, meaning it's injected beneath the skin. Your doctor or a trained healthcare professional will demonstrate the proper technique for using the pre-filled pen for self-injection. It is crucial to receive thorough training before attempting to self-administer this medication. If you are not adequately trained, please do not attempt to inject yourself.
- Never inject DARB-ESA 40 INJECTION intravenously (directly into a vein). This can lead to serious complications. If you require assistance with administering the medication, or if you have any concerns about the injection process, it is essential to visit your local hospital or clinic for professional help. Do not hesitate to seek guidance to ensure safe and effective administration.
- The appropriate dosage and frequency of DARB-ESA 40 INJECTION will be determined by your doctor based on your individual needs. Factors such as your age, weight, overall health, and the specific condition being treated will all be considered. Adhere strictly to the dosing instructions provided by your healthcare provider. Do not alter the dosage or frequency of injections without consulting with your doctor first.
- If you happen to miss a dose of DARB-ESA 40 INJECTION, administer it as soon as you remember, unless it is within 6 hours of your next scheduled dose. In that case, skip the missed dose entirely and resume your regular dosing schedule. Avoid doubling up on doses to compensate for the missed one. If you have questions on what to do in case you miss a dose, please consult your doctor.
FAQs
Can DARB-ESA 40 INJECTION be used in patients with kidney failure who are undergoing dialysis?

Yes, DARB-ESA 40 INJECTION is commonly used in patients with kidney failure who are undergoing dialysis to manage anemia.
Can DARB-ESA 40 INJECTION be used in patients with a history of heart disease?

DARB-ESA 40 INJECTION should be used with caution in patients with a history of heart disease, as it may increase the risk of certain cardiovascular events. It is crucial to discuss the potential risks and benefits with a healthcare provider before initiating treatment.
Can DARB-ESA 40 INJECTION be used to treat anemia caused by nutritional deficiencies?

DARB-ESA 40 INJECTION is not typically used to treat anemia caused by nutritional deficiencies. It is primarily used for anemia related to chronic kidney disease, cancer chemotherapy, and other specific conditions. Nutritional deficiencies require appropriate dietary changes and/or supplementation.
Can DARB-ESA 40 INJECTION be used to treat anemia in patients undergoing radiation therapy?

DARB-ESA 40 INJECTION is used to treat anemia in patients undergoing chemotherapy, depending on the specific circumstances and the healthcare provider's recommendation. The anemia is typically managed through a comprehensive treatment plan determined by the oncology team.
Can DARB-ESA 40 INJECTION interact with other medications?

DARB-ESA 40 INJECTION may interact with certain medications, such as blood thinners or immunosuppressants. It is important to inform the healthcare provider about all medications, including over-the-counter drugs and supplements, to avoid potential interactions or adverse effects.
Does DARB-ESA 40 INJECTION interact with other drugs?

DARB-ESA 40 INJECTION can interact with certain medications. It is important to tell your doctor about all your medications to avoid potential interactions.
How do I administer DARB-ESA 40 INJECTION at home?

You will be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to. Do not shake the vial or syringe. You will be shown the body areas where this shot can be given. Use a different body area each time you give yourself a shot. Keep track of where you give each shot to make sure you rotate body areas. You should stay well-hydrated, maintain a healthy diet rich in iron and other nutrients, and avoid activities that may increase your risk of injury or bleeding. It is recommended to monitor your blood counts at regular intervals. Eat less foods that contain high-sodium such as packaged snacks, canned soups, processed meats, and fast food, as too much salt can cause hypertension and fluid retention. Remember to attend all scheduled appointments and follow-up visits with your healthcare provider to ensure your treatment is effective and any side effects are managed appropriately.
What molecule/combination is used for making DARB-ESA 40 INJECTION?

DARBEPOETIN ALFA is the molecule/combination used for making DARB-ESA 40 INJECTION.
For what conditions is DARB-ESA 40 INJECTION prescribed?

DARB-ESA 40 INJECTION is prescribed for Kidney Disease.
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Reviewed on 19-01-2024
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Reviewed on 05-11-2022
(5/5)
Marketer / Manufacturer Details
SEPTALYST LIFESCIENCES PVT LTD
Country of Origin -
India
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Medkart's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, medicines, generic alternatives, all possible side effects, drug interactions, warnings, alerts, lab tests, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
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