DAXIGA VM 1000 TABLET 10'S
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DAXIGA VM 1000 TABLET 10'S
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DAXIGA VM 1000 TABLET 10'S

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DAXIGA VM 1000 TABLET 10'S

By ACMEDIX PHARMA LLP

MRP

99

₹84.15

15 % OFF

₹8.42 Only /

Tablet

10

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About DAXIGA VM 1000 TABLET 10'S

  • DAXIGA VM 1000 TABLET 10'S is a combination medicine specifically formulated to manage blood sugar levels in adults with type 2 diabetes. It combines two powerful active ingredients: Dapagliflozin and Vildagliptin, along with Metformin. This triple combination approach helps to control blood sugar through multiple mechanisms, offering a comprehensive approach to diabetes management.
  • Dapagliflozin belongs to a class of medications called SGLT2 inhibitors. It works by preventing the kidneys from reabsorbing glucose back into the blood. Instead, the excess glucose is excreted through urine, effectively lowering blood sugar levels. Vildagliptin, on the other hand, is a DPP-4 inhibitor. It enhances the levels of incretin hormones in the body. These hormones stimulate the release of insulin after meals and reduce the secretion of glucagon, a hormone that raises blood sugar levels. Metformin is a biguanide which decreases hepatic glucose production, decreases intestinal absorption of glucose, and improves insulin sensitivity by increasing peripheral glucose uptake and utilization.
  • By combining these three medications, DAXIGA VM 1000 offers a synergistic effect, providing better blood sugar control than any single medication alone. This can lead to improved HbA1c levels, a key indicator of long-term blood sugar management. It is typically prescribed when diet, exercise, and single or dual therapy with other diabetes medications are not sufficient to achieve adequate glycemic control.
  • DAXIGA VM 1000 is usually taken once or twice daily with meals, as directed by your doctor. It's crucial to follow your doctor's instructions regarding dosage and timing. Common side effects may include nausea, diarrhea, headache, and urinary tract infections. It's important to discuss any existing kidney or liver problems with your doctor before starting DAXIGA VM 1000, as dosage adjustments may be necessary. Regular monitoring of kidney function is also recommended during treatment.

Uses of DAXIGA VM 1000 TABLET 10'S

  • Treatment of type 2 diabetes mellitus
  • Lowering high blood sugar levels
  • Reducing cardiovascular risk (in patients with type 2 diabetes)
  • Slowing the progression of kidney disease (in patients with type 2 diabetes)
  • Management of obesity (in some cases)

How DAXIGA VM 1000 TABLET 10'S Works

  • DAXIGA VM 1000 Tablet 10'S is a combination medication designed to manage blood sugar levels in individuals with type 2 diabetes while also addressing certain nutritional deficiencies. Its effectiveness stems from the synergistic action of its key components: Dapagliflozin and Vildagliptin, alongside Methylcobalamin.
  • Dapagliflozin belongs to a class of drugs known as Sodium-Glucose Co-Transporter 2 (SGLT2) inhibitors. SGLT2 is a protein in the kidneys responsible for reabsorbing glucose back into the bloodstream. Dapagliflozin works by selectively blocking SGLT2. By inhibiting this protein, the drug reduces the reabsorption of glucose, leading to excess glucose being excreted through urine. This process lowers blood glucose levels and can also contribute to modest weight loss due to the calorie loss associated with glucose excretion. The mechanism is insulin-independent, which means it works even if the body's insulin production or sensitivity is impaired.
  • Vildagliptin, on the other hand, is a dipeptidyl peptidase-4 (DPP-4) inhibitor. DPP-4 is an enzyme that breaks down incretin hormones, such as glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). These incretin hormones play a crucial role in regulating blood sugar levels by stimulating insulin release from the pancreas and reducing glucagon secretion from the liver, both of which occur in a glucose-dependent manner. Vildagliptin inhibits DPP-4, thereby increasing the levels of active incretin hormones in the body. This results in enhanced insulin secretion when blood glucose levels are high and reduced glucagon secretion when blood glucose levels are low, leading to improved glycemic control.
  • Methylcobalamin is a form of vitamin B12. It plays a vital role in nerve health and function. In diabetic patients, nerve damage, known as diabetic neuropathy, is a common complication. Methylcobalamin helps in the regeneration of damaged nerves and improves nerve conduction. It acts as a cofactor in various enzymatic reactions essential for nerve cell metabolism and myelin sheath formation, thus reducing neuropathic symptoms such as pain, numbness, and tingling.
  • In summary, DAXIGA VM 1000 Tablet 10'S works through multiple pathways: Dapagliflozin lowers blood sugar by increasing glucose excretion through the kidneys. Vildagliptin enhances insulin secretion and reduces glucagon secretion by increasing incretin hormone levels. Methylcobalamin supports nerve health and helps alleviate neuropathic symptoms. This combination provides a comprehensive approach to managing type 2 diabetes and associated nerve damage.

Side Effects of DAXIGA VM 1000 TABLET 10'SArrow

Possible side effects of DAXIGA VM 1000 Tablet may include: Common side effects: Genital infections (both men and women), Urinary tract infections (UTIs), Increased urination, Thirst, Nausea, Constipation. Uncommon side effects: Fungal infections, Dehydration, Dizziness, Changes in cholesterol levels, Kidney problems. Rare side effects: Diabetic ketoacidosis (DKA). Very rare side effects: Severe allergic reaction. Other side effects: Vitamin B12 deficiency, Joint pain. This is not an exhaustive list, and it's important to consult with your doctor or pharmacist for a complete list and to report any unusual symptoms.

Safety Advice for DAXIGA VM 1000 TABLET 10'SArrow

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Allergies

Allergies

Do not use DAXIGA VM 1000 TABLET if you are allergic to it.

Dosage of DAXIGA VM 1000 TABLET 10'SArrow

  • The recommended dosage of DAXIGA VM 1000 Tablet 10'S is individualized and depends on several factors, including your blood sugar levels, kidney function, and other medications you may be taking. Your doctor will determine the appropriate dose for you.
  • Generally, DAXIGA VM 1000 Tablet 10'S is taken once daily, preferably in the morning with food. This helps to minimize potential stomach upset and also coincides with the body's natural circadian rhythm for glucose metabolism. The 'VM 1000' indicates the tablet contains a specific dosage of two active ingredients; Vildagliptin and Metformin. It is crucial not to exceed the prescribed dosage.
  • Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet, as this can affect how the medication is released and absorbed in your body. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for a missed one.
  • Regular monitoring of your blood sugar levels is essential while taking DAXIGA VM 1000 Tablet 10'S. This will help your doctor assess how well the medication is working and adjust your dosage accordingly. It's important to follow your doctor's instructions carefully and attend all scheduled appointments. Your doctor may also advise you on lifestyle modifications, such as diet and exercise, to further improve your blood sugar control.
  • Take 'DAXIGA VM 1000 TABLET 10'S' only as per the prescription by your physician only.

What if I miss my dose of DAXIGA VM 1000 TABLET 10'S?Arrow

  • If you miss a dose of DAXIGA VM 1000 TABLET 10'S, take it as soon as you remember, unless it is almost time for your next dose.
  • Do not double the dose to catch up.

How to store DAXIGA VM 1000 TABLET 10'S?Arrow

  • Keep DAXIGA VM 1000MG TAB 1X10 away from the reach of children and pets.
  • Store DAXIGA VM 1000MG TAB 1X10 at room temperature.

Benefits of DAXIGA VM 1000 TABLET 10'SArrow

  • DAXIGA VM 1000 Tablet 10'S is a combination medication formulated to manage blood sugar levels in individuals with type 2 diabetes mellitus. It combines the power of two active ingredients: Dapagliflozin and Vildagliptin, working synergistically to improve glycemic control.
  • One of the primary benefits of DAXIGA VM 1000 Tablet 10'S is its ability to lower blood sugar levels effectively. Dapagliflozin, an SGLT2 inhibitor, works by preventing the kidneys from reabsorbing glucose back into the bloodstream. Instead, excess glucose is eliminated through urine, thereby reducing blood sugar levels. Vildagliptin, a DPP-4 inhibitor, enhances the incretin system, increasing insulin release and decreasing glucagon secretion, both of which contribute to better blood sugar regulation.
  • DAXIGA VM 1000 Tablet 10'S offers a dual-action approach to managing type 2 diabetes. It helps to improve insulin sensitivity and reduce insulin resistance. This can lead to better utilization of glucose by the body's cells, ultimately lowering blood sugar levels and improving overall metabolic control.
  • Beyond blood sugar control, DAXIGA VM 1000 Tablet 10'S may also contribute to weight management. Dapagliflozin's mechanism of action, which involves the removal of excess glucose through urine, can lead to a modest calorie loss. This, combined with a healthy diet and exercise, may aid in weight management for some individuals.
  • Cardiovascular benefits have been observed with Dapagliflozin, one of the components of DAXIGA VM 1000 Tablet 10'S. Studies have shown that Dapagliflozin can reduce the risk of cardiovascular events, such as heart attack and stroke, in individuals with type 2 diabetes who also have established cardiovascular disease or multiple cardiovascular risk factors.
  • DAXIGA VM 1000 Tablet 10'S can improve HbA1c levels, which is a measure of average blood sugar control over the past 2-3 months. By effectively lowering blood sugar levels, this medication can help individuals achieve and maintain target HbA1c levels, indicating better long-term diabetes management.
  • DAXIGA VM 1000 Tablet 10'S offers the convenience of a once-daily oral medication. This can improve adherence to treatment and make it easier for individuals to incorporate the medication into their daily routine.
  • Improved beta-cell function: Vildagliptin, a component of DAXIGA VM 1000, helps to improve the function of beta cells in the pancreas, which are responsible for producing insulin. This can lead to increased insulin secretion and better blood sugar control.
  • DAXIGA VM 1000 Tablet 10'S, by effectively managing blood sugar, helps in reducing the risk of long-term complications associated with diabetes, such as nerve damage (neuropathy), kidney damage (nephropathy), eye damage (retinopathy), and cardiovascular problems.

How to use DAXIGA VM 1000 TABLET 10'SArrow

  • DAXIGA VM 1000 TABLET 10'S is an oral medication and should be taken exactly as prescribed by your doctor. Typically, it is taken once daily, preferably in the morning to coincide with your body's natural rhythms. Swallow the tablet whole with a full glass of water. Do not crush, chew, or break the tablet, as this can affect how the medication is released and absorbed.
  • It's important to take DAXIGA VM 1000 TABLET 10'S at the same time each day to maintain a consistent level of medication in your body. This helps ensure the medication works effectively. If you miss a dose, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for a missed one.
  • DAXIGA VM 1000 TABLET 10'S can be taken with or without food. However, taking it with food may help reduce the risk of stomach upset. Follow your doctor's instructions regarding dietary considerations while taking this medication. It's crucial to inform your doctor about all other medications, supplements, and herbal remedies you are currently taking, as they may interact with DAXIGA VM 1000 TABLET 10'S.
  • Continue taking DAXIGA VM 1000 TABLET 10'S for the full duration of treatment, even if you feel better. Do not stop taking the medication without consulting your doctor, as abruptly stopping it may lead to a worsening of your condition. Regular monitoring by your doctor is essential while taking DAXIGA VM 1000 TABLET 10'S to assess its effectiveness and to check for any potential side effects. Attend all scheduled appointments and report any unusual symptoms or concerns to your doctor promptly.
  • Store DAXIGA VM 1000 TABLET 10'S at room temperature, away from moisture and heat. Keep the medication out of reach of children and pets. Dispose of any unused medication properly, following your local regulations. Do not flush medication down the toilet or pour it into a drain unless instructed to do so. Consult your pharmacist for proper disposal methods.

Quick Tips for DAXIGA VM 1000 TABLET 10'SArrow

  • Take DAXIGA VM 1000 Tablet exactly as prescribed by your doctor. Do not change the dosage or stop taking the medication without consulting them, as this could affect your blood sugar levels and overall health.
  • DAXIGA VM 1000 Tablet is most effective when taken with meals. This helps to regulate blood sugar levels after eating and reduces the risk of gastrointestinal side effects. Follow your doctor's instructions on whether to take it with breakfast, lunch, or dinner.
  • Stay hydrated by drinking plenty of water throughout the day. DAXIGA VM 1000 Tablet can sometimes lead to dehydration, so it's important to maintain adequate fluid intake. Aim for at least 8 glasses of water daily, unless your doctor advises otherwise.
  • Monitor your blood sugar levels regularly as directed by your healthcare provider. This will help you understand how DAXIGA VM 1000 Tablet is working for you and allow your doctor to make any necessary adjustments to your treatment plan. Keep a record of your readings to share with your doctor.
  • Be aware of the symptoms of low blood sugar (hypoglycemia), such as shakiness, sweating, dizziness, and confusion. Carry a source of fast-acting sugar, like glucose tablets or fruit juice, with you at all times to treat hypoglycemia promptly. Contact your doctor if you experience frequent episodes of low blood sugar.
  • Inform your doctor about all other medications, supplements, and herbal remedies you are taking. Some medications can interact with DAXIGA VM 1000 Tablet and affect its effectiveness or increase the risk of side effects. This includes over-the-counter medications.
  • Maintain a healthy lifestyle by following a balanced diet and engaging in regular physical activity. DAXIGA VM 1000 Tablet works best when combined with lifestyle modifications to manage your diabetes effectively. Aim for at least 30 minutes of moderate-intensity exercise most days of the week.
  • Pay attention to your foot care. People with diabetes are at higher risk of foot problems. Inspect your feet daily for cuts, blisters, or sores, and wash and dry them thoroughly. Wear comfortable shoes and socks, and see a podiatrist regularly for foot exams.
  • If you are scheduled for any surgery or medical procedure, inform your doctor that you are taking DAXIGA VM 1000 Tablet. You may need to temporarily discontinue the medication before the procedure to prevent complications.
  • Store DAXIGA VM 1000 Tablet in a cool, dry place away from direct sunlight and moisture. Keep it out of reach of children and pets. Check the expiration date before taking the medication and discard any expired tablets properly.

FAQs

What is DAXIGA VM 1000 TABLET 10'S?Arrow

DAXIGA VM 1000 TABLET 10'S is a combination medicine used to control high blood sugar levels in adults with type 2 diabetes mellitus.

How does DAXIGA VM 1000 TABLET 10'S work?Arrow

DAXIGA VM 1000 TABLET 10'S is a combination of two medicines, Dapagliflozin and Metformin. Dapagliflozin works by preventing the kidneys from reabsorbing sugar (glucose) back into your blood and instead excretes it through your urine. Metformin works by decreasing glucose production in your liver and improving your body's sensitivity to insulin.

What are the common side effects of DAXIGA VM 1000 TABLET 10'S?Arrow

Common side effects of DAXIGA VM 1000 TABLET 10'S include nausea, vomiting, diarrhea, abdominal pain, and loss of appetite.

Is DAXIGA VM 1000 TABLET 10'S safe for patients with kidney disease?Arrow

DAXIGA VM 1000 TABLET 10'S should be used with caution in patients with kidney disease. Dosage adjustments may be necessary. Please consult your doctor.

Is DAXIGA VM 1000 TABLET 10'S safe for pregnant women?Arrow

DAXIGA VM 1000 TABLET 10'S is not recommended during pregnancy. Inform your doctor if you are pregnant or planning to become pregnant.

Is DAXIGA VM 1000 TABLET 10'S safe for breastfeeding women?Arrow

It is not known whether DAXIGA VM 1000 TABLET 10'S is excreted in breast milk. Consult your doctor before using it while breastfeeding.

How should I take DAXIGA VM 1000 TABLET 10'S?Arrow

Take DAXIGA VM 1000 TABLET 10'S exactly as prescribed by your doctor. Take it with food and drink plenty of water.

What happens if I miss a dose of DAXIGA VM 1000 TABLET 10'S?Arrow

If you miss a dose of DAXIGA VM 1000 TABLET 10'S, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose.

Can DAXIGA VM 1000 TABLET 10'S interact with other medications?Arrow

DAXIGA VM 1000 TABLET 10'S can interact with certain other medications, such as insulin, sulfonylureas, and diuretics. Tell your doctor about all the medications you are taking.

How should I store DAXIGA VM 1000 TABLET 10'S?Arrow

Store DAXIGA VM 1000 TABLET 10'S at room temperature, away from heat and moisture. Keep out of reach of children.

What are the symptoms of an overdose of DAXIGA VM 1000 TABLET 10'S?Arrow

Symptoms of an overdose of DAXIGA VM 1000 TABLET 10'S may include nausea, vomiting, diarrhea, abdominal pain, dizziness, and weakness. Seek immediate medical attention if you suspect you have taken an overdose.

Does DAXIGA VM 1000 TABLET 10'S cause weight gain?Arrow

DAXIGA VM 1000 TABLET 10'S does not typically cause weight gain. In fact, some people may experience weight loss with it.

Can I drink alcohol while taking DAXIGA VM 1000 TABLET 10'S?Arrow

Drinking alcohol while taking DAXIGA VM 1000 TABLET 10'S is not recommended, as it can increase the risk of lactic acidosis, a serious side effect.

What should I tell my doctor before taking DAXIGA VM 1000 TABLET 10'S?Arrow

Before taking DAXIGA VM 1000 TABLET 10'S, tell your doctor about all your medical conditions, especially if you have kidney disease, liver disease, heart problems, or pancreatitis. Also, tell your doctor about all the medications you are taking.

Can DAXIGA VM 1000 TABLET 10'S cause fatigue?Arrow

Some people may experience fatigue while taking DAXIGA VM 1000 TABLET 10'S. Talk to your doctor if you experience fatigue.

References

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European Medicines Agency (EMA) - Forxiga (dapagliflozin) EPAR. Provides detailed scientific information and assessment reports on dapagliflozin.

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FDA - FARXIGA (dapagliflozin) tablets prescribing information. Provides comprehensive prescribing information, including clinical pharmacology, indications, dosage, and safety.

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PubMed - A service of the National Library of Medicine, includes millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Search for 'dapagliflozin' or 'metformin' to find relevant research articles.

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ScienceDirect - A leading source for scientific, technical, and medical research. Search for 'dapagliflozin' and 'metformin' for peer-reviewed articles and studies.

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UpToDate - Drug information for Dapagliflozin. Note: Subscription may be required. Provides detailed information, including clinical use, dosing, and adverse effects.

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DrugBank - Dapagliflozin. Provides detailed drug data including mechanism of action, pharmacology, and interactions.

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DrugBank - Metformin. Provides detailed drug data including mechanism of action, pharmacology, and interactions.

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