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By INTAS PHARMACEUTICALS LIMITED
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Composition
Content Reviewed By:
Dr. Rajesh Sharma
, (MBBS)
Written By:
Ms. Priyanka Shah
, (B.Pharm)
DEPRAN 10MG TABLET 15'S can cause several side effects, although not everyone experiences them. Common side effects include nausea, dry mouth, difficulty sleeping (insomnia), drowsiness, increased sweating, and sexual dysfunction (decreased libido, ejaculatory problems). Less common side effects may include changes in appetite, weight gain or loss, anxiety, agitation, dizziness, tremor, blurred vision, palpitations, gastrointestinal disturbances (constipation, diarrhea, vomiting), skin rash, itching, and fatigue. Rare but serious side effects can include serotonin syndrome (symptoms include confusion, agitation, muscle twitching, sweating, shivering, diarrhea), seizures, and abnormal heart rhythms. Contact your doctor immediately if you experience any serious or concerning side effects.

Other medical conditions and drug interactions
Use under medical supervisionDepran 10 should be used with caution in patients with a history of seizures, bipolar disorder, suicidal ideation, respiratory disease, myasthenia gravis, or glaucoma, as the combination may exacerbate these conditions.
DEPRAN 10MG TABLET is primarily used to treat depression and anxiety disorders. It can also help manage OCD (Obsessive-Compulsive Disorder), panic disorder, and certain types of phobias.
DEPRAN 10MG TABLET is a selective serotonin reuptake inhibitor (SSRI). It works by increasing the levels of serotonin in the brain, which helps regulate mood.
Common side effects of DEPRAN 10MG TABLET include nausea, insomnia, fatigue, sweating, dry mouth, and changes in sexual function.
DEPRAN 10MG TABLET can be taken with or without food. It is best to take it at the same time each day.
If you miss a dose of DEPRAN 10MG TABLET, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule.
It is not safe to stop taking DEPRAN 10MG TABLET suddenly. This can cause withdrawal symptoms such as dizziness, nausea, anxiety, and flu-like symptoms. Always talk to your doctor about gradually reducing the dosage.
Before taking DEPRAN 10MG TABLET, tell your doctor about all your medical conditions, allergies, and medications you are taking.
Yes, DEPRAN 10MG TABLET can interact with certain other medications. Tell your doctor about all the medications you are taking, especially MAO inhibitors, warfarin, and NSAIDs.
Talk to your doctor before taking DEPRAN 10MG TABLET during pregnancy or breastfeeding. This medication may harm the unborn baby or breastfeeding infant.
Store DEPRAN 10MG TABLET at room temperature, away from heat and moisture. Keep it out of reach of children and pets.
It may take a few weeks for DEPRAN 10MG TABLET to start working. Continue taking it regularly to see the maximum benefit.
DEPRAN 10MG TABLET is not addictive, but stopping it suddenly can cause withdrawal symptoms.
Drinking alcohol while taking DEPRAN 10MG TABLET can increase side effects, so it is best to avoid it.
Weight gain is a possible side effect of DEPRAN 10MG TABLET in some people. Talk to your doctor if you are concerned about this.
Some other brands of Escitalopram include Citalo, Esopram, and Lexapro.
Depran 10 is a prescription medicine containing escitalopram (an SSRI antidepressant) and clonazepam (a benzodiazepine). It is generally used for depressive disorders associated with significant anxiety, generalized anxiety disorder, and other anxiety-related conditions, as assessed by a psychiatrist or physician. The escitalopram component helps improve mood and reduce depressive symptoms over time, while clonazepam provides short- to medium-term relief from anxiety, tension, and agitation. The exact indication for an individual patient should be confirmed with the treating doctor.
Depran 10 works through two complementary mechanisms. Escitalopram selectively inhibits the reuptake of serotonin in the brain, increasing its availability in synapses and helping to stabilize mood, reduce depressive symptoms, and alleviate anxiety over several weeks. Clonazepam enhances the effect of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, by acting on GABA-A receptors. This produces anxiolytic, sedative, and muscle-relaxant effects, leading to quicker relief of anxiety and associated physical symptoms. The combination aims to provide both early symptom relief and longer-term mood stabilization, but it must be used under close medical supervision.
The clonazepam component of Depran 10 usually starts to reduce anxiety, restlessness, and tension within hours to a few days of starting treatment, depending on individual response and the prescribed regimen. The escitalopram component typically requires 1 to 2 weeks for initial improvement in mood and anxiety, and up to 4 to 6 weeks or longer for full therapeutic benefit. Some patients may notice better sleep or reduced worry before mood improves. If there is no meaningful improvement after several weeks, or if symptoms worsen, the patient should consult the prescribing doctor for reassessment.
Yes, the clonazepam component can cause physical dependence, especially if used at higher doses or for prolonged periods. Stopping clonazepam abruptly after long-term use may lead to withdrawal symptoms such as rebound anxiety, insomnia, irritability, tremor, sweating, or, rarely, seizures. For this reason, Depran 10 should be used for the shortest duration necessary, and any discontinuation or dose reduction should be gradual and supervised by a doctor. Escitalopram can also cause discontinuation symptoms if stopped suddenly, including dizziness, sensory disturbances, sleep problems, and mood changes. A slow taper is usually recommended for both components.
Common side effects of Depran 10 may include drowsiness, dizziness, fatigue, slowed reaction time, dry mouth, nausea, indigestion, constipation or diarrhea, increased sweating, headache, and changes in sleep pattern. Some patients may experience decreased libido, delayed ejaculation, or difficulty achieving orgasm due to escitalopram. Clonazepam can cause sedation, muscle weakness, and impaired coordination. Many side effects are mild and may lessen as the body adjusts to treatment, but persistent, troublesome, or severe symptoms should be discussed with the prescribing doctor.
Depran 10 can be prescribed to older adults, but it requires particular caution. Older patients are more sensitive to benzodiazepines like clonazepam and have a higher risk of excessive sedation, confusion, falls, fractures, and cognitive impairment. They may also be more susceptible to hyponatremia and other adverse effects of SSRIs such as escitalopram. Dose selection, treatment duration, and monitoring should be individualized and conservative in this age group. Any new confusion, unsteadiness, memory problems, or sudden change in behavior should be reported promptly to the doctor.
Alcohol should be avoided while taking Depran 10. Both clonazepam and alcohol depress the central nervous system, and their combined effect can lead to excessive drowsiness, impaired coordination, slowed breathing, and increased risk of accidents or falls. Alcohol may also worsen anxiety and depression in the longer term and can interfere with the therapeutic effect of escitalopram. Patients should be advised not to consume alcoholic beverages or use other sedating substances without medical approval during treatment.
The clonazepam component of Depran 10 has a recognized potential for habit formation and dependence, particularly with long-term use, higher doses, or use in individuals with a history of substance misuse. Psychological dependence may also develop if the medicine is used as the primary coping strategy for stress or anxiety. To minimize this risk, Depran 10 is usually prescribed for a limited duration, with regular review of the ongoing need for clonazepam. Patients should not increase the dose, take extra tablets, or continue therapy beyond the prescribed period without consulting their doctor.
Depran 10 should not be stopped suddenly without medical advice, even if you feel better. Abrupt discontinuation of clonazepam can cause withdrawal symptoms such as rebound anxiety, insomnia, irritability, tremor, and, in rare cases, seizures. Stopping escitalopram suddenly can lead to discontinuation symptoms including dizziness, electric shock-like sensations, sleep disturbances, mood swings, and flu-like symptoms. Your doctor will usually recommend a gradual dose reduction over weeks to minimize these risks and monitor for any return or worsening of symptoms.
Depran 10 may be unsuitable for people with known allergy or hypersensitivity to escitalopram, clonazepam, other benzodiazepines, or any excipients in the formulation. It is generally contraindicated in patients with severe respiratory insufficiency, acute narrow-angle glaucoma, severe liver impairment, or myasthenia gravis, and in those taking certain monoamine oxidase inhibitors (MAOIs) or other medicines that strongly interact with escitalopram. It should be used with great caution in individuals with a history of substance use disorder, suicidal behavior, bipolar disorder, or seizure disorders. A full medical history and medication list should be shared with the prescribing doctor before starting therapy.
Use of Depran 10 in children or adolescents is generally not routine and, if considered at all, should be strictly under specialist psychiatric supervision. SSRIs, including escitalopram, have been associated with an increased risk of suicidal thoughts and behavior in children, adolescents, and young adults, particularly at the start of treatment or after dose changes. Benzodiazepines like clonazepam can also cause paradoxical reactions such as increased agitation or irritability in younger patients. Any use in this age group requires careful risk–benefit assessment, close monitoring, and informed discussion with caregivers.
Depran 10MG Tablet 15's is used for certain seizure disorders; panic disorder; some movement disorders — under specialist direction; and major depressive disorder; generalised anxiety disorder; panic disorder; some other anxiety conditions. Depran 10MG Tablet 15's contains Clonazepam 0.5 MG + Escitalopram Oxalate 10 MG. Always use Depran 10MG Tablet 15's as advised by your doctor.
Depran 10MG Tablet 15's contains Clonazepam 0.5 MG + Escitalopram Oxalate 10 MG. It is a benzodiazepine anticonvulsant/anxiolytic; and SSRI antidepressant.
Commonly reported side effects of Depran 10MG Tablet 15's include drowsiness, fatigue, unsteadiness, poor coordination, memory and concentration problems, behavioural changes; and nausea, sleep disturbance, drowsiness, sweating, sexual dysfunction, dry mouth, reduced appetite. Not everyone gets side effects. Tell your doctor or pharmacist if any effect persists or worries you.
Depran 10MG Tablet 15's is listed at Rs. 237.06 on Medkart. Prices can change — check the product page for the current price and pack size.
Prescription-only and controlled; and Increased suicidal thinking in children, adolescents and young adults — close monitoring early in treatment and after dose changes. Tell your doctor about all other medicines you take before starting Depran 10MG Tablet 15's.
The dose of Depran 10MG Tablet 15's depends on your condition, age, weight and other medicines you take, so it must be decided by your doctor. Follow the dose and duration on your prescription and do not change it on your own.
A generic medicine is one with the same active composition as the branded product — for Depran 10MG Tablet 15's that is Clonazepam 0.5 MG + Escitalopram Oxalate 10 MG. Medkart lists generic options by composition so you can compare. Ask your doctor or pharmacist before switching from Depran 10MG Tablet 15's.
Depran 10MG Tablet 15's contains Clonazepam 0.5 MG + Escitalopram Oxalate 10 MG, a benzodiazepine anticonvulsant/anxiolytic; and SSRI antidepressant. It is used for certain seizure disorders.
Yes. Depran 10MG Tablet 15's requires a valid doctor's prescription.
Depran 10MG Tablet 15's is manufactured by Intas Pharmaceuticals Limited.
Depran 10MG Tablet 15's is supplied as a tablet and is taken by the oral route.
Depran 10MG Tablet 15's contains Clonazepam 0.5 MG + Escitalopram Oxalate 10 MG. It is used for certain seizure disorders; panic disorder; some movement disorders — under specialist direction; and major depressive disorder; generalised anxiety disorder; panic disorder; some other anxiety conditions. The benefit you get depends on the condition your doctor prescribed Depran 10MG Tablet 15's for.
Whether Depran 10MG Tablet 15's can be taken daily, and for how long, depends on your condition and must be decided by your doctor. Do not start, extend or repeat a course of Depran 10MG Tablet 15's on your own.
The timing of Depran 10MG Tablet 15's depends on the dose your doctor prescribes and on the other medicines you take. Follow the timing on your prescription or ask your pharmacist.
No. Depran 10MG Tablet 15's is a prescription medicine and should only be taken on a doctor's advice.
Do not take Depran 10MG Tablet 15's during pregnancy or while breastfeeding without asking your doctor. Safety depends on the medicine, the stage of pregnancy and your own health.
Check with your doctor before drinking alcohol while taking Depran 10MG Tablet 15's. Alcohol can add to side effects such as drowsiness and can affect how some medicines work.
Store Depran 10MG Tablet 15's in its original pack, below 25°C unless the pack states otherwise, away from direct sunlight and moisture, and out of the reach of children. Do not use it after the expiry date on the pack.
Often get medicines at a cheaper rate. Almost 50% cheaper
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Reviewed on 10-06-2023
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Good discount available on Generic medicines and supportive staff. Thank you.
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Reviewed on 08-01-2024
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Genuine product....
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Reviewed on 11-01-2024
(5/5)
Good for generic medicine, quality medicine with affordable rate
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Reviewed on 03-02-2024
(5/5)
Best and cheapest medicine.
Shubham Jain
•
Reviewed on 23-11-2022
(5/5)
INTAS PHARMACEUTICALS LIMITED
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India

MRP
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278.9
₹237.06
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