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Composition
Content Reviewed By:
Dr. Sanjay Mehta
, (MBBS)
Written By:
Ms. Kavita Desai
, (B.Pharm)
Common side effects of Nexito Forte Tablet may include nausea, vomiting, diarrhea, constipation, dry mouth, increased sweating, changes in appetite, weight changes, dizziness, drowsiness, headache, insomnia (difficulty sleeping), fatigue, blurred vision, sexual dysfunction (decreased libido, erectile dysfunction, ejaculatory problems), and anxiety. Less common side effects can include restlessness, agitation, panic attacks, confusion, memory problems, difficulty concentrating, abnormal dreams, tremor, muscle stiffness, movement disorders, changes in blood pressure, heart palpitations, skin rash, itching, hair loss, and changes in menstruation. Rare but serious side effects include serotonin syndrome (symptoms may include high fever, agitation, confusion, tremors, and rapid heart rate), angle-closure glaucoma, seizures, and suicidal thoughts or behaviors. It is important to consult your doctor if you experience any of these side effects or any other unusual symptoms.

Allergies
CONTRAINDICATEDDo not take Nexito Forte if you are allergic to escitalopram, clonazepam, other SSRIs, benzodiazepines, or any ingredient in the formulation.
NEXITO FORTE TABLET 10'S is a medication used to treat depression and anxiety disorders. It contains a combination of escitalopram and clonazepam.
NEXITO FORTE TABLET 10'S works by increasing the levels of chemical messengers in the brain that help to improve mood and reduce anxiety.
Common side effects of NEXITO FORTE TABLET 10'S include nausea, vomiting, diarrhea, constipation, fatigue, dizziness, and decreased sexual desire.
NEXITO FORTE TABLET 10'S contains clonazepam, which can be habit-forming. Take it only as prescribed by your doctor.
If you miss a dose of NEXITO FORTE TABLET 10'S, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose.
Avoid drinking alcohol while taking NEXITO FORTE TABLET 10'S, as it can increase the side effects.
Store NEXITO FORTE TABLET 10'S at room temperature, away from heat and moisture. Keep it out of reach of children.
Consult your doctor before taking NEXITO FORTE TABLET 10'S during pregnancy. It may harm the fetus.
Consult your doctor before taking NEXITO FORTE TABLET 10'S during breastfeeding. It may pass into breast milk and harm the baby.
NEXITO FORTE TABLET 10'S can interact with certain other medications. Tell your doctor about all the medications you are taking, including over-the-counter drugs and herbal supplements.
If you overdose on NEXITO FORTE TABLET 10'S, seek immediate medical attention. Symptoms of an overdose may include drowsiness, confusion, difficulty breathing, and coma.
Do not stop taking NEXITO FORTE TABLET 10'S abruptly. It can cause withdrawal symptoms. Talk to your doctor before stopping the medication.
Weight gain is a possible side effect of NEXITO FORTE TABLET 10'S in some people. Talk to your doctor if you are concerned about this.
Other medications that contain a combination of escitalopram and clonazepam include Escitap C and Clopinex Plus. Always consult your doctor.
NEXITO FORTE TABLET 10'S can be taken with or without food, but it is best to take it at the same time each day.
Nexito Forte is mainly used to treat depression and various anxiety disorders, such as generalized anxiety disorder and panic disorder. It helps improve mood, reduce excessive worry, and relieve physical symptoms of anxiety like restlessness, palpitations, and sleep disturbance. The exact indication for you will depend on your doctor’s assessment of your symptoms and medical history.
Nexito Forte usually contains escitalopram, an SSRI, and clonazepam, a benzodiazepine. Escitalopram increases serotonin levels in the brain, which helps stabilize mood and reduce depressive symptoms. Clonazepam enhances the effect of gamma-aminobutyric acid (GABA), a calming neurotransmitter, thereby reducing anxiety, tension, and panic. Together, they provide both antidepressant and anti-anxiety effects.
The benzodiazepine component (clonazepam) can cause dependence if used for a long time or at higher than prescribed doses. This means you may experience withdrawal symptoms such as anxiety, irritability, tremors, or sleep problems if the medicine is stopped abruptly. To minimize this risk, Nexito Forte should be used only as prescribed, for the shortest duration necessary, and discontinued gradually under medical supervision.
Alcohol should be avoided while taking Nexito Forte. Both alcohol and the benzodiazepine component depress the central nervous system, which can lead to excessive drowsiness, poor coordination, slowed breathing, and impaired judgment. Alcohol can also worsen anxiety and depression over time, reducing the overall benefit of treatment.
Nexito Forte is generally not considered a first-choice medicine in pregnancy. SSRIs and benzodiazepines may carry risks such as withdrawal symptoms or breathing difficulties in the newborn if used in late pregnancy, and there may be other potential effects on fetal development. Your doctor will weigh the benefits of treating severe anxiety or depression against these risks. Never start or stop Nexito Forte during pregnancy without consulting your doctor.
Both escitalopram and clonazepam can pass into breast milk in varying amounts. This may cause drowsiness, poor feeding, or irritability in the breastfed baby, especially with higher doses or prolonged use. Nexito Forte is usually avoided or used with great caution during breastfeeding. If your doctor decides it is necessary, your baby should be closely monitored for any unusual symptoms.
People with liver or kidney impairment may not clear escitalopram and clonazepam from the body as efficiently, leading to higher blood levels and increased side effects such as drowsiness or confusion. In such cases, doctors may choose a lower strength, adjust the dosing schedule, or select an alternative medicine. Always inform your doctor about any history of liver disease, hepatitis, cirrhosis, or kidney problems before starting Nexito Forte.
Yes. Nexito Forte can cause drowsiness, dizziness, blurred vision, and slowed reaction time, especially when you first start treatment or when the dose is changed. These effects can impair your ability to drive, ride a bike, or operate machinery safely. Do not drive or perform tasks that require full alertness until you know how the medicine affects you and your doctor confirms it is safe.
If you have ever had an allergic reaction to escitalopram, clonazepam, other SSRIs, benzodiazepines, or any inactive ingredient in the tablet, you must inform your doctor before taking Nexito Forte. Signs of an allergic reaction include rash, itching, swelling of the face or throat, severe dizziness, or difficulty breathing. If any of these occur after taking the medicine, seek emergency medical help and do not take further doses.
Nexito Forte should not be stopped suddenly without medical advice. Abrupt discontinuation can cause withdrawal symptoms such as anxiety, irritability, mood swings, sleep problems, headache, nausea, or, in the case of benzodiazepines, even seizures in susceptible individuals. Your doctor will usually reduce the dose gradually over weeks to minimize these effects and monitor for any return of symptoms.
Some relief in anxiety may be noticed within a few days due to the benzodiazepine component, but the full antidepressant effect of escitalopram typically takes 2 to 4 weeks or longer. It is important to continue taking the medicine as prescribed even if you do not feel better immediately. Regular follow-up with your doctor is essential to assess response and adjust treatment if needed.
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