DICORATE ER 125MG TABLET 10'S
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DICORATE ER 125MG TABLET 10'SDICORATE ER 125MG TABLET 10'SDICORATE ER 125MG TABLET 10'S
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DICORATE ER 125MG TABLET 10'S

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DICORATE ER 125MG TABLET 10'S

By SUN PHARMACEUTICAL INDUSTRIES LTD

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₹52.7

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About DICORATE ER 125MG TABLET 10'S

  • DICORATE ER 125MG TABLET 10'S is a medication primarily used in the treatment of epilepsy and bipolar disorder. It contains valproic acid as its active ingredient, which is a mood stabilizer and an anticonvulsant. This extended-release formulation ensures a sustained release of the medication, providing a consistent therapeutic effect over a longer period.
  • Valproic acid works by increasing the levels of gamma-aminobutyric acid (GABA) in the brain, a neurotransmitter that reduces neuronal excitability. By enhancing GABA activity, DICORATE ER helps to stabilize mood and prevent seizures. It is effective in managing various types of seizures, including absence seizures, myoclonic seizures, and tonic-clonic seizures.
  • Besides epilepsy, DICORATE ER is also prescribed for the maintenance treatment of bipolar disorder, helping to prevent manic episodes. It works by modulating the balance of certain brain chemicals, reducing the extreme mood swings associated with this condition. This helps patients maintain a more stable emotional state, improving their overall quality of life.
  • The extended-release formulation of DICORATE ER 125MG offers several advantages. It reduces the frequency of dosing, improving patient compliance and convenience. The sustained release also minimizes fluctuations in drug levels, reducing the risk of side effects associated with peak concentrations. It is generally recommended to take this medicine as directed by your healthcare provider, usually once or twice daily, with or without food. Regular monitoring of liver function and blood counts may be necessary during treatment to ensure safety and efficacy.
  • This medication is generally well-tolerated, but some common side effects may include nausea, vomiting, diarrhea, tremor, and weight gain. It is important to discuss any concerns or existing medical conditions with your doctor before starting DICORATE ER. Pregnant women should exercise caution, as valproic acid can pose risks to the developing fetus. Overall, DICORATE ER 125MG TABLET 10'S is a valuable medication for managing epilepsy and bipolar disorder, providing patients with a more stable and improved quality of life.

Uses of DICORATE ER 125MG TABLET 10'S

  • Control of epileptic seizures
  • Mood stabilization in bipolar disorder
  • Migraine prevention
  • Management of neuropathic pain
  • Treatment of psychiatric disorders

How DICORATE ER 125MG TABLET 10'S Works

  • DICORATE ER 125MG TABLET 10'S contains Sodium Valproate, a mood-stabilizing medication primarily used in the treatment of epilepsy and bipolar disorder. It functions through several mechanisms within the brain to achieve its therapeutic effects. One of the primary ways Sodium Valproate works is by increasing the levels of gamma-aminobutyric acid (GABA) in the brain. GABA is an inhibitory neurotransmitter, meaning it reduces the excitability of neurons. By boosting GABA levels, Sodium Valproate helps to calm overactive nerve cells, which is particularly beneficial in controlling seizures associated with epilepsy.
  • Furthermore, Sodium Valproate affects voltage-gated sodium channels. These channels are crucial for the transmission of electrical signals along nerve cells. The medication slows the recovery of these sodium channels from their inactive state. This action reduces the sustained high-frequency firing of neurons, which is often seen during seizures. By stabilizing the neuronal membrane, DICORATE ER 125MG TABLET 10'S helps to prevent the spread of abnormal electrical activity in the brain.
  • In addition to its effects on GABA and sodium channels, Sodium Valproate also influences other neurotransmitter systems. It is believed to modulate the activity of glutamate, an excitatory neurotransmitter. By reducing glutamate's activity, Sodium Valproate further contributes to the overall calming effect on the brain. The extended-release (ER) formulation of DICORATE ER 125MG TABLET 10'S ensures a gradual release of the medication into the bloodstream. This helps to maintain a consistent level of the drug in the body throughout the day, reducing fluctuations that can lead to breakthrough symptoms or side effects. This consistent release aids in better seizure control and mood stabilization with a reduced dosing frequency.

Side Effects of DICORATE ER 125MG TABLET 10'SArrow

Common side effects of Dicorate ER 125mg Tablet may include nausea, vomiting, stomach pain, diarrhea, constipation, loss of appetite, headache, dizziness, drowsiness, blurred vision, double vision, hair loss, weight gain, tremor, and difficulty in coordination. Less common but potentially serious side effects include liver problems (such as jaundice), pancreatitis, low blood cell counts, severe skin reactions, and allergic reactions. Mood changes, depression, anxiety, and suicidal thoughts are also possible. If you experience any unusual or severe symptoms, consult your doctor immediately.

Safety Advice for DICORATE ER 125MG TABLET 10'SArrow

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Allergies

Allergies

Do not use DICORATE ER 125MG TABLET 10'S if you are allergic to it or any of its ingredients.

Dosage of DICORATE ER 125MG TABLET 10'SArrow

  • The recommended dosage of DICORATE ER 125MG TABLET 10'S varies significantly depending on the individual's condition, age, and response to treatment. It is crucial to adhere strictly to the dosage prescribed by your physician. Typically, the initial dosage for adults might range from 250mg to 500mg daily, divided into multiple doses. The extended-release formulation of DICORATE ER allows for once-daily or twice-daily administration, simplifying the dosing schedule and improving patient compliance. The physician will gradually increase the dosage until the desired therapeutic effect is achieved, while closely monitoring for any potential side effects.
  • For children, the dosage is determined based on their weight and the severity of the condition. Accurate weight measurement is essential for calculating the correct dose. The physician will provide specific instructions regarding the dose and frequency of administration. It is important to note that DICORATE ER 125MG TABLET 10'S should be swallowed whole and not crushed or chewed, as this can affect the extended-release mechanism and lead to unpredictable drug release. If swallowing the tablet is difficult, consult your physician for alternative formulations or methods of administration.
  • Regular monitoring of blood levels of valproic acid, the active ingredient in DICORATE ER, is often necessary to ensure that the drug concentration remains within the therapeutic range. This helps to optimize the treatment and minimize the risk of adverse effects. It's very important not to adjust your dosage without consulting your doctor. If you miss a dose, take it as soon as you remember unless it is almost time for your next scheduled dose. In that case, skip the missed dose and resume your regular dosing schedule. Do not double up on doses to compensate for the missed one. Take 'DICORATE ER 125MG TABLET 10'S' only as per the prescription by your physician only.

What if I miss my dose of DICORATE ER 125MG TABLET 10'S?Arrow

  • If you miss a dose of DICORATE ER 125MG TABLET 10'S, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

How to store DICORATE ER 125MG TABLET 10'S?Arrow

  • Keep DICORATE ER 125MG TAB 1X10 away from the reach of children and pets.
  • Store DICORATE ER 125MG TAB 1X10 at room temperature.

Benefits of DICORATE ER 125MG TABLET 10'SArrow

  • DICORATE ER 125MG TABLET 10'S is a medication primarily used in the treatment of epilepsy and bipolar disorder. Its extended-release formulation ensures a steady release of the active ingredient, valproic acid, over a longer period, which helps in maintaining consistent blood levels and reducing the frequency of seizures or mood swings. In epilepsy, DICORATE ER 125MG TABLET 10'S works by increasing the levels of a calming chemical in the brain called gamma-aminobutyric acid (GABA). GABA helps to reduce the excitability of nerve cells, thus preventing seizures. It is effective in controlling various types of seizures, including generalized tonic-clonic seizures, absence seizures, and partial seizures.
  • In bipolar disorder, DICORATE ER 125MG TABLET 10'S acts as a mood stabilizer. It helps to balance the levels of neurotransmitters in the brain, which are responsible for regulating mood. By stabilizing these neurotransmitters, DICORATE ER 125MG TABLET 10'S can reduce the severity and frequency of manic and depressive episodes associated with bipolar disorder. This can lead to improved mood, better sleep, and increased overall functioning in individuals with bipolar disorder.
  • Another significant benefit of DICORATE ER 125MG TABLET 10'S is its ability to prevent migraine headaches. While the exact mechanism is not fully understood, valproic acid is believed to influence neurotransmitters and reduce inflammation in the brain, thereby preventing the onset of migraines. For individuals who experience frequent or severe migraines, DICORATE ER 125MG TABLET 10'S can significantly improve their quality of life by reducing the frequency and intensity of headaches.
  • The extended-release formulation of DICORATE ER 125MG TABLET 10'S offers several advantages over immediate-release formulations. It reduces the need for multiple daily doses, improving patient compliance and convenience. The steady release of valproic acid also minimizes fluctuations in blood levels, which can reduce the risk of side effects and improve the overall effectiveness of the medication. This is particularly beneficial for individuals who require long-term treatment for epilepsy or bipolar disorder.
  • Furthermore, DICORATE ER 125MG TABLET 10'S can improve the overall quality of life for individuals suffering from these conditions. By effectively controlling seizures, mood swings, and migraines, it allows individuals to lead more normal and productive lives. Patients may experience improved cognitive function, better social interactions, and increased ability to participate in daily activities. The use of DICORATE ER 125MG TABLET 10'S should always be under the guidance and supervision of a healthcare professional to ensure appropriate dosage and monitoring for potential side effects. Regular check-ups and blood tests may be necessary to monitor liver function and valproic acid levels in the blood.

How to use DICORATE ER 125MG TABLET 10'SArrow

  • DICORATE ER 125MG TABLET 10'S is an extended-release formulation of divalproex sodium, a mood stabilizer and anticonvulsant medication. It is primarily prescribed for the treatment of epilepsy, bipolar disorder, and migraine headaches. Always adhere to your doctor's instructions regarding dosage and duration.
  • Swallow the tablet whole with a glass of water. Do not crush, chew, or break the tablet, as this can affect the extended-release mechanism and potentially lead to a rapid release of the drug, increasing the risk of side effects or reducing the medication's effectiveness. Take DICORATE ER 125MG TABLET 10'S at the same time(s) each day to maintain a consistent level of medication in your bloodstream. This regularity helps to optimize its therapeutic effects.
  • DICORATE ER 125MG TABLET 10'S can be taken with or without food. If you experience stomach upset, taking it with food may help. However, consistency is key, so try to take it the same way each day.
  • If you miss a dose of DICORATE ER 125MG TABLET 10'S, take it as soon as you remember, unless it is almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule. Do not double your dose to make up for a missed one.
  • Long-term use of DICORATE ER 125MG TABLET 10'S requires regular monitoring by your doctor. This may include blood tests to check liver function, platelet count, and valproic acid levels in your blood. Follow your doctor's recommendations and attend all scheduled appointments.
  • Do not abruptly stop taking DICORATE ER 125MG TABLET 10'S, as this can increase the risk of seizures or mood destabilization. Your doctor will guide you on how to safely and gradually reduce the dose if discontinuation is necessary. Discuss any concerns or side effects you experience with your doctor.

Quick Tips for DICORATE ER 125MG TABLET 10'SArrow

  • Take DICORATE ER 125MG TABLET 10'S exactly as prescribed by your doctor. Do not change the dose or stop taking it without consulting your healthcare provider, as this could lead to a worsening of your condition or withdrawal symptoms. Consistency is key for optimal results; take it at the same time each day to maintain a steady level of medication in your body. This helps in better management of your symptoms, whether you are taking it for epilepsy, bipolar disorder, or migraine prevention.
  • Be aware of potential side effects. Common side effects may include nausea, vomiting, headache, drowsiness, dizziness, and changes in appetite or weight. If these side effects persist or become bothersome, inform your doctor. More serious side effects, such as liver problems, pancreatitis, or allergic reactions (rash, itching, swelling), require immediate medical attention. Regularly monitor your health and report any unusual symptoms to your healthcare provider.
  • Inform your doctor about all other medications, supplements, and herbal products you are taking. DICORATE ER 125MG TABLET 10'S can interact with other drugs, potentially altering their effects or increasing the risk of side effects. This includes over-the-counter medications, vitamins, and herbal remedies. A complete medication history helps your doctor make informed decisions about your treatment plan and avoid potential drug interactions.
  • If you are a woman of childbearing age, discuss the risks and benefits of taking DICORATE ER 125MG TABLET 10'S with your doctor. Valproate, the active ingredient in this medication, can cause birth defects if taken during pregnancy. Effective contraception is essential if you are sexually active and not planning to become pregnant. Explore alternative treatment options with your doctor if you are planning a pregnancy or become pregnant while taking this medication.
  • Store DICORATE ER 125MG TABLET 10'S properly, away from moisture and heat, and out of reach of children and pets. Keep the medication in its original container, tightly closed. Do not store it in the bathroom, as the humidity can affect its efficacy. Check the expiration date regularly, and dispose of any expired medication safely, following your local guidelines for medication disposal. Proper storage ensures the medication remains effective and prevents accidental ingestion.

Food Interactions with DICORATE ER 125MG TABLET 10'SArrow

  • DICORATE ER 125MG TABLET 10'S may be taken with or without food, but it is important to take it consistently with respect to meals. Taking it with food may help reduce stomach upset. Avoid alcohol consumption while taking this medicine, as it may increase the risk of side effects.

FAQs

What is Dicorate ER 125mg Tablet 10's?Arrow

Dicorate ER 125mg Tablet 10's is a medicine used to treat epilepsy, bipolar disorder, and migraine.

What is Dicorate ER 125mg Tablet 10's used for?Arrow

It is used to treat epilepsy, bipolar disorder, and migraine.

How does Dicorate ER 125mg Tablet 10's work?Arrow

It works by decreasing the abnormal and excessive activity of the nerve cells in the brain.

What are the common side effects of Dicorate ER 125mg Tablet 10's?Arrow

Common side effects include nausea, vomiting, diarrhea, stomach pain, loss of appetite, weight gain, and hair loss.

Is Dicorate ER 125mg Tablet 10's safe for pregnant women?Arrow

Using Dicorate ER 125mg Tablet 10's during pregnancy can increase the risk of birth defects. Therefore, pregnant women should consult a doctor before using it.

What is the dosage of Dicorate ER 125mg Tablet 10's?Arrow

The dosage is determined by the doctor. It depends on the severity of the condition and the patient's response.

Can Dicorate ER 125mg Tablet 10's be taken with or without food?Arrow

It is recommended to take it with food.

How to store Dicorate ER 125mg Tablet 10's?Arrow

Store it at room temperature, away from direct sunlight and moisture.

Is Dicorate ER 125mg Tablet 10's addictive?Arrow

No, this medicine is not habit-forming.

What happens if I miss a dose of Dicorate ER 125mg Tablet 10's?Arrow

If you miss a dose, take it as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and continue with your regular schedule.

Can Dicorate ER 125mg Tablet 10's cause weight gain?Arrow

Yes, weight gain is a common side effect in some patients.

What is the active ingredient in Dicorate ER 125mg Tablet 10's?Arrow

The active ingredient in Dicorate ER 125mg Tablet 10's is Sodium Valproate.

Can Dicorate ER 125mg Tablet 10's be stopped suddenly?Arrow

No, Dicorate ER 125mg Tablet 10's should not be stopped suddenly as it can increase the risk of seizures. It should always be stopped gradually as per the doctor's advice.

Can Dicorate ER 125mg Tablet 10's interact with other medications?Arrow

Yes, Dicorate ER 125mg Tablet 10's can interact with some other medications. Therefore, it is important to tell your doctor about all the medications you are taking.

What are the alternatives to Dicorate ER 125mg Tablet 10's?Arrow

Alternatives to Dicorate ER 125mg Tablet 10's include Valproic Acid, Lamotrigine, Topiramate, and Carbamazepine.

References

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DrugBank: Valproic Acid. This entry provides comprehensive information on valproic acid, including its mechanism of action, uses, and pharmacokinetics.

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FDA Prescribing Information: Depakote ER (divalproex sodium extended-release tablets). This is the official prescribing information for a related extended-release divalproex sodium product, detailing usage, dosage, and potential side effects.

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PubChem: Valproic Acid. This entry provides chemical properties, structure, and related information for valproic acid.

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NCBI Bookshelf: Valproate. This resource offers a detailed overview of valproate, covering aspects from its pharmacology to clinical applications and adverse effects.

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European Medicines Agency: Valproate medicines: reminder of restrictions and measures to avoid use in pregnancy. Provides safety information and usage restrictions, particularly regarding pregnancy.

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